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Search results 1201 to 1300 out of 1376 for Mycn

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Type Details Score
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Allele
Tg(Th-MYCN)41Waw | MGI:3039395
Name: transgene insertion 41, William A Weiss
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
27769070 | J:339434
First Author: Fielitz K
Year: 2016
Journal: Oncotarget
Title: Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells.
Volume: 7
Issue: 46
Pages: 74415-74426
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Publication
12880978 | J:85004
First Author: Hogarty MD
Year: 2003
Journal: Cancer Lett
Title: The requirement for evasion of programmed cell death in neuroblastomas with MYCN amplification.
Volume: 197
Issue: 1-2
Pages: 173-9
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HT Experiment
E-MTAB-5671 | RNA-seq of E10.5 limb mesenchymal cells from mice with mutations in Mycn and mir17-92
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
17449239 | J:122306
First Author: Cheng AJ
Year: 2007
Journal: Eur J Cancer
Title: Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma.
Volume: 43
Issue: 9
Pages: 1467-75
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Publication
38001143 | J:343065
First Author: Schoof M
Year: 2023
Journal: Nat Commun
Title: Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures.
Volume: 14
Issue: 1
Pages: 7717
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Publication
19608868 | J:150780
First Author: Alam G
Year: 2009
Journal: Am J Pathol
Title: MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development.
Volume: 175
Issue: 2
Pages: 856-66
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Publication
19047152 | J:142092
First Author: Hogarty MD
Year: 2008
Journal: Cancer Res
Title: ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma.
Volume: 68
Issue: 23
Pages: 9735-45
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Publication
17710228 | J:127480
First Author: Song L
Year: 2007
Journal: J Clin Invest
Title: Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma.
Volume: 117
Issue: 9
Pages: 2702-12
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Publication
26068589 | J:258951
First Author: Petroni M
Year: 2016
Journal: Cell Death Differ
Title: The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress.
Volume: 23
Issue: 2
Pages: 197-206
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Publication
28574509 | J:268301
First Author: Delaidelli A
Year: 2017
Journal: Cell Death Differ
Title: MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation.
Volume: 24
Issue: 9
Pages: 1564-1576
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Publication
8174136 | J:18224
First Author: Ferrandis E
Year: 1994
Journal: Cancer Res
Title: Coactivation of the MDR1 and MYCN genes in human neuroblastoma cells during the metastatic process in the nude mouse.
Volume: 54
Issue: 8
Pages: 2256-61
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Publication
36869047 | J:333935
First Author: Mainwaring OJ
Year: 2023
Journal: Nat Commun
Title: ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors.
Volume: 14
Issue: 1
Pages: 1221
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Transgene
MGI:2673317 | Tg(Th-MYCN)41Waw
Type: transgene
Organism: mouse, laboratory
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Publication
22907398 | J:193509
First Author: Schramm A
Year: 2013
Journal: Int J Cancer
Title: Next-generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in MYCN-amplified neuroblastoma.
Volume: 132
Issue: 3
Pages: E106-15
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Publication
24391509 | J:226671
First Author: Suenaga Y
Year: 2014
Journal: PLoS Genet
Title: NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas.
Volume: 10
Issue: 1
Pages: e1003996
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GXD Expression
GXD Expression
Probe: MGI:6403207
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6403266
Age: embryonic day 10.5
Image: 2G
Note: Same as the wild-type, indicating the staining was not due to cross-reaction with Mycn and nonspecificity of unknown origin.
Specimen Label: 2G
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6403207
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6403266
Age: embryonic day 10.5
Image: S1A/B Mycn-cKO
Note: Same as the wild-type, indicating the staining was not due to cross-reaction with Mycn and nonspecificity of unknown origin.
Specimen Label: S1A/B Mycn-cKO
Detected: true
Specimen Num: 4
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Publication
11861392 | -
First Author: Shohet JM
Year: 2002
Journal: Cancer Res
Title: Minichromosome maintenance protein MCM7 is a direct target of the MYCN transcription factor in neuroblastoma.
Volume: 62
Issue: 4
Pages: 1123-8
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Publication
10882752 | -
First Author: Frühwald MC
Year: 2000
Journal: J Med Genet
Title: Gene amplification in PNETs/medulloblastomas: mapping of a novel amplified gene within the MYCN amplicon.
Volume: 37
Issue: 7
Pages: 501-9
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Publication
9516855 | -
First Author: Ross RA
Year: 1997
Journal: Eur J Cancer
Title: HuD, a neuronal-specific RNA-binding protein, is a potential regulator of MYCN expression in human neuroblastoma cells.
Volume: 33
Issue: 12
Pages: 2071-4
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Allele
Mycn<tm1Smoc> | MGI:7291203
Name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tg(tetO-MYCN,-luc)#Waw | MGI:5570746
Name: transgene insertion, William A Weiss
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence, Reporter
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Strain
MGI:6770965 | C57BL/6JSmoc-Mycn<tm1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Col1a1<tm6.1(tetO-Mycn,-mCherry)Yasu> | MGI:7509704
Name: collagen, type I, alpha 1; targeted mutation 6.1, Yasuhiro Yamada
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence, Reporter
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Publication
25174395 | J:222527
First Author: Althoff K
Year: 2015
Journal: Oncogene
Title: A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies.
Volume: 34
Issue: 26
Pages: 3357-68
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Publication
25533335 | J:218831
First Author: Hill RM
Year: 2015
Journal: Cancer Cell
Title: Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease.
Volume: 27
Issue: 1
Pages: 72-84
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Publication
25294817 | J:317516
First Author: Beckers A
Year: 2015
Journal: Oncotarget
Title: MYCN-targeting miRNAs are predominantly downregulated during MYCN‑driven neuroblastoma tumor formation.
Volume: 6
Issue: 7
Pages: 5204-16
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Allele
Gt(ROSA)26Sor<tm1(CAG-MYCN,-luc)Jhsc> | MGI:6196127
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Johannes H Schulte
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter, RMCE-ready
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Publication
35508126 | J:325007
First Author: Trieu KG
Year: 2022
Journal: Cell Rep
Title: Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease.
Volume: 39
Issue: 5
Pages: 110779
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Publication
34099734 | J:307910
First Author: Brady NJ
Year: 2021
Journal: Nat Commun
Title: Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.
Volume: 12
Issue: 1
Pages: 3372
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Allele
Myc<tm39Mnz> | MGI:3720515
Name: myelocytomatosis oncogene; targeted mutation 39, Michel C Nussenzweig
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Tg(Slc1a2-tTA)#Waw/? Tg(tetO-MYCN,-luc)#Waw/?
Background: involves: FVB/NJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Slc1a2-tTA)#Waw/? Tg(tetO-MYCN,-luc)#Waw/Tg(tetO-MYCN,-luc)#Waw
Background: involves: FVB/NJ
Zygosity: cx
Has Mutant Allele: true
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Publication
26766585 | J:231324
First Author: Mathsyaraja H
Year: 2016
Journal: Cancer Cell
Title: Parsing Myc Paralogs in Oncogenesis.
Volume: 29
Issue: 1
Pages: 1-2
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Publication
38636893 | J:350799
 
First Author: Zhuo R
Year: 2024
Journal: Cancer Lett
Title: CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma.
Volume: 591
Pages: 216882
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Dbh-icre)1Gsc/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
23475876 | J:198393
First Author: Schnepp RW
Year: 2013
Journal: Cancer Discov
Title: Targeting MYCN: a good BET for improving neuroblastoma therapy?
Volume: 3
Issue: 3
Pages: 255-7
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HT Experiment
GSE162238 | Single cell RNA seq of the developing murine adrenal gland reveals correlation of Schwann cell precursor signature to neuroblastoma phenotype.
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Strain
MGI:5655321 | B6(Cg)-Myc<tm39Mnz>/J
Attribute String: targeted mutation, mutant strain, coisogenic
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Publication
36219398 | J:332175
First Author: Borgenvik A
Year: 2022
Journal: Cancer Res
Title: Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma.
Volume: 82
Issue: 24
Pages: 4586-4603
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Genotype
Genotype
Symbol: Myc/Myc<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
22340591 | J:181462
First Author: Kawauchi D
Year: 2012
Journal: Cancer Cell
Title: A mouse model of the most aggressive subgroup of human medulloblastoma.
Volume: 21
Issue: 2
Pages: 168-80
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Publication
27050099 | J:231826
First Author: Lee JK
Year: 2016
Journal: Cancer Cell
Title: N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells.
Volume: 29
Issue: 4
Pages: 536-547
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Publication
27396325 | J:238681
First Author: Ribeiro D
Year: 2016
Journal: Cell Rep
Title: Regulation of Nuclear Hormone Receptors by MYCN-Driven miRNAs Impacts Neural Differentiation and Survival in Neuroblastoma Patients.
Volume: 16
Issue: 4
Pages: 979-993
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Publication
26766587 | J:231323
First Author: Vo BT
Year: 2016
Journal: Cancer Cell
Title: The Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup Identity.
Volume: 29
Issue: 1
Pages: 5-16
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Publication
38016952 | J:360598
First Author: Ji Y
Year: 2023
Journal: Nat Commun
Title: The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer.
Volume: 14
Issue: 1
Pages: 7794
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Publication
30315164 | J:267604
First Author: Singh BN
Year: 2018
Journal: Nat Commun
Title: A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human.
Volume: 9
Issue: 1
Pages: 4237
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Publication
28637693 | J:245948
First Author: Fell SM
Year: 2017
Journal: Genes Dev
Title: Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.
Volume: 31
Issue: 10
Pages: 1036-1053
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Publication
15743832 | J:97664
First Author: Cardone M
Year: 2005
Journal: Mol Cell Biol
Title: The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis.
Volume: 25
Issue: 6
Pages: 2395-405
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Publication
24465765 | J:212335
First Author: Smith S
Year: 2014
Journal: PLoS One
Title: LIM domain only-2 (LMO2) induces T-cell leukemia by two distinct pathways.
Volume: 9
Issue: 1
Pages: e85883
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Publication
26537256 | J:234050
First Author: Carter DR
Year: 2015
Journal: Sci Transl Med
Title: Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma.
Volume: 7
Issue: 312
Pages: 312ra176
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Publication
23243020 | J:194367
First Author: Kishida S
Year: 2013
Journal: Cancer Res
Title: Midkine promotes neuroblastoma through Notch2 signaling.
Volume: 73
Issue: 4
Pages: 1318-27
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Publication
28739902 | J:244650
First Author: Dyberg C
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Rho-associated kinase is a therapeutic target in neuroblastoma.
Volume: 114
Issue: 32
Pages: E6603-E6612
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Publication
23792191 | J:199151
First Author: Brockmann M
Year: 2013
Journal: Cancer Cell
Title: Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma.
Volume: 24
Issue: 1
Pages: 75-89
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Publication
33768209 | J:313873
First Author: Roeschert I
Year: 2021
Journal: Nat Cancer
Title: Combined inhibition of Aurora-A and ATR kinase results in regression of MYCN-amplified neuroblastoma.
Volume: 2
Issue: 3
Pages: 312-326
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Publication
37696947 | J:341095
First Author: Collignon E
Year: 2023
Journal: Nat Cell Biol
Title: m(6)A RNA methylation orchestrates transcriptional dormancy during paused pluripotency.
Volume: 25
Issue: 9
Pages: 1279-1289
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Publication
26597947 | J:233968
First Author: Borriello L
Year: 2016
Journal: Cancer Lett
Title: More than the genes, the tumor microenvironment in neuroblastoma.
Volume: 380
Issue: 1
Pages: 304-14
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Publication
31375684 | J:279483
First Author: Dammert MA
Year: 2019
Journal: Nat Commun
Title: MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer.
Volume: 10
Issue: 1
Pages: 3485
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Publication
38992040 | J:351291
First Author: Murray JE
Year: 2024
Journal: Nat Commun
Title: The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis.
Volume: 15
Issue: 1
Pages: 5585
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Genotype
Genotype
Symbol: Aicda/Aicda<+> Igh/Igh<+> Myc/Myc<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Rb1/Rb1 Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Rb1/Rb1<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Publication
29492199 | J:320562
First Author: De Wilde B
Year: 2018
Journal: Oncotarget
Title: The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease.
Volume: 9
Issue: 9
Pages: 8334-8349
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Protein Coding Gene
MGI:1332242 | Mycs
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0035501 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035479 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035412 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1332242 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035999 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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