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Search results 1201 to 1300 out of 1389 for Nr5a1

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Hits by Strain

Type Details Score
Allele
Nr5a1<em2Smoc> | MGI:7291402
Name: nuclear receptor subfamily 5, group A, member 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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DO Term
DOID:0111772 | 46,XY sex reversal 3
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Strain
MGI:3708180 | FVB-Tg(Nr5a1-cre)2Lowl/J
Attribute String: transgenic, mutant strain, coisogenic
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Strain
MGI:4437688 | STOCK Tg(Nr5a1-cre)7Lowl/J
Attribute String: transgenic
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Strain
MGI:6303606 | B6J.FVB(129)-Tg(Nr5a1-cre)7Lowl/RujfJ
Attribute String: congenic, mutant strain, transgenic
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Publication
33879780 | J:312119
First Author: Lee ML
Year: 2021
Journal: Nat Commun
Title: Prostaglandin in the ventromedial hypothalamus regulates peripheral glucose metabolism.
Volume: 12
Issue: 1
Pages: 2330
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Publication
38161999 | J:344164
 
First Author: Shao J
Year: 2023
Journal: Front Cell Neurosci
Title: Ventromedial hypothalamus relays chronic stress inputs and exerts bidirectional regulation on anxiety state and related sympathetic activity.
Volume: 17
Pages: 1281919
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Publication
28673934 | J:247917
First Author: Coutinho EA
Year: 2017
Journal: Diabetes
Title: Activation of SF1 Neurons in the Ventromedial Hypothalamus by DREADD Technology Increases Insulin Sensitivity in Peripheral Tissues.
Volume: 66
Issue: 9
Pages: 2372-2386
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Allele
Tg(Nr5a1-cre)#Lowl | MGI:4440636
Name: transgene insertion, Bradford B Lowell
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:6771005 | C57BL/6JSmoc-Nr5a1<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Rr401<em1Yushi> | MGI:7448545
Name: regulatory region 401; endonuclease-mediated mutation 1, Yuichi Shima
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Genotype
Genotype
Symbol: Tg(Nr5a1-cre)2Lowl/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
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Allele
Tg(Nr5a1-cre)5Asc | MGI:3041879
Name: transgene insertion 5, Andreas Schedl
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
25754823 | J:221125
First Author: Wang L
Year: 2015
Journal: Neuron
Title: Collateral pathways from the ventromedial hypothalamus mediate defensive behaviors.
Volume: 85
Issue: 6
Pages: 1344-58
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Publication
25748136 | J:220696
   
First Author: Kunwar PS
Year: 2015
Journal: Elife
Title: Ventromedial hypothalamic neurons control a defensive emotion state.
Volume: 4
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Allele
Nr5a1<em1Smoc> | MGI:7291401
Name: nuclear receptor subfamily 5, group A, member 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
36713379 | J:355402
 
First Author: Wu CH
Year: 2022
Journal: Front Immunol
Title: Relative adrenal insufficiency is a risk factor and endotype of sepsis - A proof-of-concept study to support a precision medicine approach to guide glucocorticoid therapy for sepsis.
Volume: 13
Pages: 1110516
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Publication
33021968 | J:299977
 
First Author: Sun JS
Year: 2021
Journal: J Clin Invest
Title: Ventromedial hypothalamic primary cilia control energy and skeletal homeostasis.
Volume: 131
Issue: 1
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Publication
31314542 | J:279262
First Author: Senn SS
Year: 2019
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Unsilencing of native LepRs in hypothalamic SF1 neurons does not rescue obese phenotype in LepR-deficient mice.
Volume: 317
Issue: 3
Pages: R451-R460
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Genotype
Genotype
Symbol: Rr401/Rr401
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr401/Rr401<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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HT Experiment
GSE216420 | Role of steroidogenic factor 1 in the regulation of the ovarian reserve
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
36928253 | J:339170
First Author: Leng L
Year: 2023
Journal: PLoS Biol
Title: Hypothalamic Menin regulates systemic aging and cognitive decline.
Volume: 21
Issue: 3
Pages: e3002033
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Publication
28987511 | J:249768
 
First Author: Ramos-Lobo AM
Year: 2017
Journal: Neuroscience
Title: SOCS3 ablation in SF1 cells causes modest metabolic effects during pregnancy and lactation.
Volume: 365
Pages: 114-124
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Publication
27422385 | J:247100
First Author: Steinbusch LK
Year: 2016
Journal: Diabetes
Title: Sex-Specific Control of Fat Mass and Counterregulation by Hypothalamic Glucokinase.
Volume: 65
Issue: 10
Pages: 2920-31
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Allele
Tg(Nr5a1-EGFP)NB184Gsat | MGI:4940673
Name: transgene insertion NB184, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Nr5a1-cre)SB15Gsat | MGI:5311726
Name: transgene insertion SB15, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Nr5a1-cre)SB4Gsat | MGI:5311757
Name: transgene insertion SB4, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Gt(ROSA)26Sor<tm2(CAG-Nr5a1)Fjd> | MGI:6275547
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Franco J DeMayo
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Strain
MGI:6771004 | C57BL/6JSmoc-Nr5a1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Rr403-lacZ)#Kmor | MGI:7448939
Name: transgene insertion, Ken-ichirou Morohashi
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr402-lacZ)#Kmor | MGI:7448930
Name: transgene insertion, Ken-ichirou Morohashi
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr401-EGFP)4Kmor | MGI:7448534
Name: transgene insertion 4, Ken-ichirou Morohashi
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr61430-EGFP)#Kmor | MGI:7448539
Name: transgene insertion, Ken-ichirou Morohashi
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Lepr/Lepr Tg(Nr5a1-cre)2Lowl/?
Background: involves: 129 * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lepr/Lepr Tg(Nr5a1-cre)7Lowl/?
Background: involves: 129 * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mc3r/Mc3r Tg(Nr5a1-cre)2Lowl/?
Background: involves: C57BL/6J * FVB/NJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdh1/Cdh1 Tg(Nr5a1-cre)7Lowl/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxo1/Foxo1 Tg(Nr5a1-cre)#Lowl/?
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkx2-1/Nkx2-1 Tg(Nr5a1-cre)7Lowl/?
Background: involves: 129X1/SvJ * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17 Tg(Nr5a1-cre)2Lowl/?
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE171746 | Bulk RNA-seq of fetal and adult murine Leydig cells
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE156176 | Single-cell RNA-seq profiling of early murine adrenogonadal development
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
37633515 | J:340328
 
First Author: Yoshida T
Year: 2023
Journal: Mol Metab
Title: VMHdm/c(SF-1) neuronal circuits regulate skeletal muscle PGC1-α via the sympathoadrenal drive.
Volume: 77
Pages: 101792
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Publication
35119382 | J:325976
First Author: Piprek RP
Year: 2022
Journal: Reproduction
Title: Desmoplakin (Dsp) conditional knockout in NR5A1+ somatic cells affects germ cell survival in developing mouse gonads.
Volume: 163
Issue: 4
Pages: 199-207
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Publication
26988598 | J:259565
 
First Author: Saito K
Year: 2016
Journal: Sci Rep
Title: PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice.
Volume: 6
Pages: 23459
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Publication
28811293 | J:257891
First Author: Burmeister MA
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: The glucagon-like peptide-1 receptor in the ventromedial hypothalamus reduces short-term food intake in male mice by regulating nutrient sensor activity.
Volume: 313
Issue: 6
Pages: E651-E662
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Publication
32337532 | J:292651
 
First Author: Felsted JA
Year: 2020
Journal: Endocrinology
Title: Sex-specific Effects of α2δ-1 in the Ventromedial Hypothalamus of Female Mice Controlling Glucose and Lipid Balance.
Volume: 161
Issue: 7
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Publication
30104247 | J:265904
First Author: Seoane-Collazo P
Year: 2018
Journal: Diabetes
Title: SF1-Specific AMPKα1 Deletion Protects Against Diet-Induced Obesity.
Volume: 67
Issue: 11
Pages: 2213-2226
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Publication
31028248 | J:300208
First Author: Fujikawa T
Year: 2019
Journal: Exp Mol Med
Title: P110β in the ventromedial hypothalamus regulates glucose and energy metabolism.
Volume: 51
Issue: 4
Pages: 1-9
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Strain
MGI:5004309 | STOCK Tg(Nr5a1-EGFP)NB184Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Strain
MGI:5312995 | STOCK Tg(Nr5a1-cre)SB15Gsat/Mmucd
Attribute String: transgenic, mutant stock
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Strain
MGI:5313026 | STOCK Tg(Nr5a1-cre)SB4Gsat/Mmucd
Attribute String: transgenic, mutant stock
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Allele
Tg(Nr5a1-EGFP)#Kmor | MGI:7448551
Name: transgene insertion, Ken-ichirou Morohashi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Allele
Tg(Rr61430-EGFP)LBmutKmor | MGI:7448555
Name: transgene insertion LBmut, Ken-ichirou Morohashi
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr61430-mCherry)LBmutKmor | MGI:7448557
Name: transgene insertion LBmut, Ken-ichirou Morohashi
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Sox9/Sox9<+> Tg(Nr5a1-cre)5Asc/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox9/Sox9 Tg(Nr5a1-cre)5Asc/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nr2c2/Nr2c2 Tg(Nr5a1-cre)#Lowl/?
Background: involves: FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rai1/Rai1 Tg(Nr5a1-cre)7Lowl/?
Background: either: (involves: 129S1/Sv * C57BL/6 * FVB) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB)
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rai1/Rai1<+> Tg(Nr5a1-cre)7Lowl/?
Background: either: (involves: 129S1/Sv * C57BL/6 * FVB) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB)
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dsp/Dsp Tg(Nr5a1-cre)7Lowl/?
Background: involves: 129 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Nr5a1-cre)2Lowl/?
Background: involves: 129X1/SvJ * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata6/Gata6 Tg(Nr5a1-cre)2Lowl/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
19940178 | J:158472
First Author: Hawke Z
Year: 2009
Journal: J Neurosci
Title: PACAP neurons in the hypothalamic ventromedial nucleus are targets of central leptin signaling.
Volume: 29
Issue: 47
Pages: 14828-35
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Publication
32839348 | J:300713
First Author: Quenneville S
Year: 2020
Journal: Diabetes
Title: Hypoglycemia-Sensing Neurons of the Ventromedial Hypothalamus Require AMPK-Induced Txn2 Expression but Are Dispensable for Physiological Counterregulation.
Volume: 69
Issue: 11
Pages: 2253-2266
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Publication
30343141 | J:270369
First Author: Fan J
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Nr5a1-Cre-mediated Tspo conditional knockout mice with low growth rate and prediabetes symptoms - A mouse model of stress diabetes.
Volume: 1865
Issue: 1
Pages: 56-62
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Publication
29085897 | J:247512
 
First Author: Tomorsky J
Year: 2017
Journal: eNeuro
Title: TU-Tagging: A Method for Identifying Layer-Enriched Neuronal Genes in Developing Mouse Visual Cortex.
Volume: 4
Issue: 5
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Publication
33048320 | J:306981
First Author: Khawar MB
Year: 2021
Journal: Protein Cell
Title: Sirt1 regulates testosterone biosynthesis in Leydig cells via modulating autophagy.
Volume: 12
Issue: 1
Pages: 67-75
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Publication
36405866 | J:355065
First Author: Abou Nader N
Year: 2022
Journal: J Endocr Soc
Title: Effect of Inactivation of Mst1 and Mst2 in the Mouse Adrenal Cortex.
Volume: 7
Issue: 1
Pages: bvac143
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Publication
32243503 | J:289490
 
First Author: Ménard A
Year: 2020
Journal: Endocrinology
Title: Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate.
Volume: 161
Issue: 5
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Publication
28938438 | J:249889
First Author: Levasseur A
Year: 2017
Journal: Endocrinology
Title: Targeted Disruption of YAP and TAZ Impairs the Maintenance of the Adrenal Cortex.
Volume: 158
Issue: 11
Pages: 3738-3753
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Publication
25763637 | J:222087
First Author: Orozco-Solis R
Year: 2015
Journal: Endocrinology
Title: SIRT1 Relays Nutritional Inputs to the Circadian Clock Through the Sf1 Neurons of the Ventromedial Hypothalamus.
Volume: 156
Issue: 6
Pages: 2174-84
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Publication
33303759 | J:300990
First Author: Zhang J
Year: 2020
Journal: Nat Commun
Title: An excitatory ventromedial hypothalamus to paraventricular thalamus circuit that suppresses food intake.
Volume: 11
Issue: 1
Pages: 6326
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Genotype
Genotype
Symbol: Lepr/Lepr Tg(Nr5a1-cre)2Lowl/? Tg(Pomc1-cre)16Lowl/?
Background: involves: 129 * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sirt1/Sirt1 Tg(Nr5a1-cre)#Lowl/?
Background: involves: 129S6/SvEvTac * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Nr5a1-cre)7Lowl/?
Background: involves: FVB
Zygosity: cn
Has Mutant Allele: true
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Publication
31100714 | J:285721
First Author: Piprek RP
Year: 2019
Journal: Reproduction
Title: Tissue-specific knockout of E-cadherin (Cdh1) in developing mouse gonads causes germ cells loss.
Volume: 158
Issue: 2
Pages: 147-157
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Publication
29262334 | J:255693
First Author: Viskaitis P
Year: 2017
Journal: Cell Rep
Title: Modulation of SF1 Neuron Activity Coordinately Regulates Both Feeding Behavior and Associated Emotional States.
Volume: 21
Issue: 12
Pages: 3559-3572
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Publication
37261917 | J:345310
 
First Author: Tu L
Year: 2023
Journal: J Clin Invest
Title: Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia.
Volume: 133
Issue: 14
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Publication
20620998 | J:163161
First Author: Xu Y
Year: 2010
Journal: Cell Metab
Title: PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis.
Volume: 12
Issue: 1
Pages: 88-95
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Publication
26959185 | J:233003
First Author: Orozco-Solis R
Year: 2016
Journal: Cell Metab
Title: The Circadian Clock in the Ventromedial Hypothalamus Controls Cyclic Energy Expenditure.
Volume: 23
Issue: 3
Pages: 467-78
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Allele
Tg(Nr5a1/EGFP)1Klp | MGI:5493455
Name: transgene insertion 1, Keith L Parker
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Sox8/Sox8<+> Sox9/Sox9 Tg(Nr5a1-cre)5Asc/?
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox8/Sox8 Sox9/Sox9 Tg(Nr5a1-cre)5Asc/?
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Rspo1/Rspo1 Tg(Nr5a1-cre)5Asc/?
Background: involves: 129/Sv * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Bgeo/GFP)21Lbe/? Tg(Nr5a1-cre)2Lowl/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Bgeo/GFP)21Lbe/? Tg(Nr5a1-cre)2Lowl/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Bgeo/GFP)21Lbe/? Tg(Nr5a1-cre)7Lowl/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Nr5a1-cre)2Lowl/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Publication
21505076 | J:172807
First Author: Bouhali K
Year: 2011
Journal: Hum Mol Genet
Title: Allelic reduction of Dlx5 and Dlx6 results in early follicular depletion: a new mouse model of primary ovarian insufficiency.
Volume: 20
Issue: 13
Pages: 2642-50
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Publication
23536856 | J:199495
First Author: Fortin J
Year: 2013
Journal: PLoS One
Title: NR5A2 regulates Lhb and Fshb transcription in gonadotrope-like cells in vitro, but is dispensable for gonadotropin synthesis and fertility in vivo.
Volume: 8
Issue: 3
Pages: e59058
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Publication
38467682 | J:346611
First Author: Banik J
Year: 2024
Journal: Sci Rep
Title: The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs.
Volume: 14
Issue: 1
Pages: 5918
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