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Search results 1201 to 1300 out of 1843 for Pomc

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Type Details Score
Publication
32747560 | J:293753
First Author: Zhang Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Hypothalamic extended synaptotagmin-3 contributes to the development of dietary obesity and related metabolic disorders.
Volume: 117
Issue: 33
Pages: 20149-20158
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Publication
31494175 | J:282888
 
First Author: Quaresma PGF
Year: 2019
Journal: Mol Cell Endocrinol
Title: Growth hormone/STAT5 signaling in proopiomelanocortin neurons regulates glucoprivic hyperphagia.
Volume: 498
Pages: 110574
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Transgene
MGI:4367778 | Tg(Pomc-cre)5Brn
Type: transgene
Organism: mouse, laboratory
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Publication
36442744 | J:334308
 
First Author: Qiu J
Year: 2022
Journal: Mol Metab
Title: CRISPR/SaCas9 mutagenesis of stromal interaction molecule 1 in proopiomelanocortin neurons increases glutamatergic excitability and protects against diet-induced obesity.
Volume: 66
Pages: 101645
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Publication
34153315 | J:312546
 
First Author: Leyrer-Jackson JM
Year: 2021
Journal: Neuropharmacology
Title: Alcohol consumption preferentially activates a subset of pro-opiomelanocortin (POMC) producing neurons targeting the amygdala.
Volume: 195
Pages: 108674
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Publication
30445039 | J:268003
First Author: Brandt C
Year: 2018
Journal: Cell
Title: Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation.
Volume: 175
Issue: 5
Pages: 1321-1335.e20
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Publication
32206712 | J:289901
First Author: Lee EJ
Year: 2020
Journal: Sci Adv
Title: A psychological stressor conveyed by appetite-linked neurons.
Volume: 6
Issue: 12
Pages: eaay5366
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Publication
27211900 | J:251958
First Author: Kuperman Y
Year: 2016
Journal: Cell Metab
Title: CRFR1 in AgRP Neurons Modulates Sympathetic Nervous System Activity to Adapt to Cold Stress and Fasting.
Volume: 23
Issue: 6
Pages: 1185-1199
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Publication
23529161 | J:210125
First Author: Dubinion JH
Year: 2013
Journal: Hypertension
Title: Role of proopiomelanocortin neuron Stat3 in regulating arterial pressure and mediating the chronic effects of leptin.
Volume: 61
Issue: 5
Pages: 1066-74
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Publication
33293550 | J:300977
First Author: Kwon E
Year: 2020
Journal: Nat Commun
Title: Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production.
Volume: 11
Issue: 1
Pages: 6295
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Publication
24177424 | J:207704
First Author: Berglund ED
Year: 2013
Journal: J Clin Invest
Title: Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis.
Volume: 123
Issue: 12
Pages: 5061-70
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Publication
22761160 | J:189527
First Author: De Jonghe BC
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency.
Volume: 303
Issue: 5
Pages: E644-51
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Publication
24155320 | J:204670
First Author: Ito Y
Year: 2013
Journal: J Neurosci
Title: GABA type B receptor signaling in proopiomelanocortin neurons protects against obesity, insulin resistance, and hypothalamic inflammation in male mice on a high-fat diet.
Volume: 33
Issue: 43
Pages: 17166-73
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Publication
35490865 | J:325651
 
First Author: Ma Y
Year: 2022
Journal: Mol Metab
Title: Neuronal miR-29a protects from obesity in adult mice.
Volume: 61
Pages: 101507
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Publication
27199455 | J:242422
First Author: Stump M
Year: 2016
Journal: Physiol Genomics
Title: Effect of selective expression of dominant-negative PPARγ in pro-opiomelanocortin neurons on the control of energy balance.
Volume: 48
Issue: 7
Pages: 491-501
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Publication
23785158 | J:199640
First Author: Schmid T
Year: 2013
Journal: J Neurosci
Title: Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity.
Volume: 33
Issue: 25
Pages: 10459-70
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Publication
34504172 | J:313887
First Author: Moura-Assis A
Year: 2021
Journal: Sci Rep
Title: TLR4-interactor with leucine-rich repeats (TRIL) is involved in diet-induced hypothalamic inflammation.
Volume: 11
Issue: 1
Pages: 18015
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Publication
33255553 | J:304994
 
First Author: Chaves FM
Year: 2020
Journal: Int J Mol Sci
Title: Tumor Necrosis Factor α and Interleukin-1β Acutely Inhibit AgRP Neurons in the Arcuate Nucleus of the Hypothalamus.
Volume: 21
Issue: 23
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Publication
24374551 | J:209418
First Author: Sasaki T
Year: 2014
Journal: Diabetologia
Title: Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice.
Volume: 57
Issue: 4
Pages: 819-31
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Publication
31863824 | J:336891
 
First Author: Nogueira G
Year: 2020
Journal: Brain Behav Immun
Title: Interleukin-17 acts in the hypothalamus reducing food intake.
Volume: 87
Pages: 272-285
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Publication
29791746 | J:341544
     
First Author: Calarco CA
Year: 2018
Journal: Eur J Neurosci
Title: Molecular and cellular characterization of nicotinic acetylcholine receptor subtypes in the arcuate nucleus of the mouse hypothalamus.
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Publication
26318021 | J:226412
First Author: Biehl MJ
Year: 2015
Journal: Dev Biol
Title: Rbpj-κ mediated Notch signaling plays a critical role in development of hypothalamic Kisspeptin neurons.
Volume: 406
Issue: 2
Pages: 235-46
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Publication
26375425 | J:232752
First Author: Zhu L
Year: 2015
Journal: Endocrinology
Title: The ERα-PI3K Cascade in Proopiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice.
Volume: 156
Issue: 12
Pages: 4474-91
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Publication
22941110 | J:204885
First Author: Huang H
Year: 2012
Journal: Nat Neurosci
Title: Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.
Volume: 15
Issue: 10
Pages: 1391-8
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Publication
22285542 | J:182297
First Author: Coupé B
Year: 2012
Journal: Cell Metab
Title: Loss of autophagy in pro-opiomelanocortin neurons perturbs axon growth and causes metabolic dysregulation.
Volume: 15
Issue: 2
Pages: 247-55
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Publication
19767734 | J:154300
First Author: Plum L
Year: 2009
Journal: Nat Med
Title: The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake.
Volume: 15
Issue: 10
Pages: 1195-201
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Publication
23119079 | J:192274
First Author: Marino JS
Year: 2012
Journal: PLoS One
Title: Adipocyte dysfunction in a mouse model of polycystic ovary syndrome (PCOS): evidence of adipocyte hypertrophy and tissue-specific inflammation.
Volume: 7
Issue: 10
Pages: e48643
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Publication
21642975 | J:174009
First Author: Klöckener T
Year: 2011
Journal: Nat Neurosci
Title: High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.
Volume: 14
Issue: 7
Pages: 911-8
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Publication
26910012 | J:231078
 
First Author: Vernia S
Year: 2016
Journal: Elife
Title: Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress.
Volume: 5
Pages: e10031
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Publication
30310864 | J:268184
 
First Author: Stincic TL
Year: 2018
Journal: eNeuro
Title: Estradiol Drives the Anorexigenic Activity of Proopiomelanocortin Neurons in Female Mice.
Volume: 5
Issue: 4
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Publication
28166221 | J:243793
First Author: Campbell JN
Year: 2017
Journal: Nat Neurosci
Title: A molecular census of arcuate hypothalamus and median eminence cell types.
Volume: 20
Issue: 3
Pages: 484-496
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Publication
36889283 | J:334320
First Author: González-García I
Year: 2023
Journal: Cell Metab
Title: Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1.
Volume: 35
Issue: 3
Pages: 438-455.e7
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Publication
21187319 | J:176858
First Author: Yadav VK
Year: 2011
Journal: J Exp Med
Title: Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications.
Volume: 208
Issue: 1
Pages: 41-52
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Publication
24229711 | J:206734
First Author: Zhao H
Year: 2013
Journal: Cancer Cell
Title: Skp2 deletion unmasks a p27 safeguard that blocks tumorigenesis in the absence of pRb and p53 tumor suppressors.
Volume: 24
Issue: 5
Pages: 645-59
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Publication
19966802 | J:155967
First Author: Wang H
Year: 2010
Journal: Nat Genet
Title: Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice.
Volume: 42
Issue: 1
Pages: 83-8
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Publication
24632684 | J:210319
 
First Author: Lu Z
Year: 2014
Journal: Nat Commun
Title: Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity.
Volume: 5
Pages: 3463
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Publication
34400471 | J:316939
 
First Author: Chang CC
Year: 2021
Journal: eNeuro
Title: Laser Capture Microdissection of Single Neurons with Morphological Visualization Using Fluorescent Proteins Fused to Transmembrane Proteins.
Volume: 8
Issue: 5
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Publication
18160639 | J:130955
First Author: Gao X
Year: 2007
Journal: J Neurosci
Title: Conditional knock-out of beta-catenin in postnatal-born dentate gyrus granule neurons results in dendritic malformation.
Volume: 27
Issue: 52
Pages: 14317-25
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Publication
19014937 | J:144750
First Author: Gao X
Year: 2009
Journal: Exp Neurol
Title: Impaired dendritic development and synaptic formation of postnatal-born dentate gyrus granular neurons in the absence of brain-derived neurotrophic factor signaling.
Volume: 215
Issue: 1
Pages: 178-90
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Publication
16423694 | J:105327
First Author: Dhillon H
Year: 2006
Journal: Neuron
Title: Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis.
Volume: 49
Issue: 2
Pages: 191-203
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Publication
35873003 | J:359025
 
First Author: Murgia N
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: In Vivo Reductionist Approach Identifies miR-15a Protecting Mice From Obesity.
Volume: 13
Pages: 867929
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Publication
34233196 | J:330752
First Author: Uemura M
Year: 2021
Journal: Cell Rep
Title: A neurogenic microenvironment defined by excitatory-inhibitory neuronal circuits in adult dentate gyrus.
Volume: 36
Issue: 1
Pages: 109324
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Publication
30143607 | J:266387
First Author: Quiñones M
Year: 2018
Journal: Nat Commun
Title: p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1.
Volume: 9
Issue: 1
Pages: 3432
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Publication
30507615 | J:270522
First Author: Zhou QG
Year: 2019
Journal: J Clin Invest
Title: Chemogenetic silencing of hippocampal neurons suppresses epileptic neural circuits.
Volume: 129
Issue: 1
Pages: 310-323
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Publication
21048120 | J:166702
First Author: Xu Y
Year: 2010
Journal: J Neurosci
Title: A serotonin and melanocortin circuit mediates D-fenfluramine anorexia.
Volume: 30
Issue: 44
Pages: 14630-4
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Publication
35091292 | J:339270
 
First Author: Brix LM
Year: 2022
Journal: Psychoneuroendocrinology
Title: The co-chaperone FKBP51 modulates HPA axis activity and age-related maladaptation of the stress system in pituitary proopiomelanocortin cells.
Volume: 138
Pages: 105670
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Publication
34031591 | J:321274
First Author: Perino A
Year: 2021
Journal: Nat Metab
Title: Central anorexigenic actions of bile acids are mediated by TGR5.
Volume: 3
Issue: 5
Pages: 595-603
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Publication
31277924 | J:284545
First Author: Alhadeff AL
Year: 2019
Journal: Neuron
Title: Natural and Drug Rewards Engage Distinct Pathways that Converge on Coordinated Hypothalamic and Reward Circuits.
Volume: 103
Issue: 5
Pages: 891-908.e6
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Publication
32678476 | J:317450
First Author: Barbier M
Year: 2021
Journal: J Comp Neurol
Title: Projections from the dorsomedial division of the bed nucleus of the stria terminalis to hypothalamic nuclei in the mouse.
Volume: 529
Issue: 5
Pages: 929-956
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Publication
29915194 | J:264637
First Author: Hunt DL
Year: 2018
Journal: Nat Neurosci
Title: A novel pyramidal cell type promotes sharp-wave synchronization in the hippocampus.
Volume: 21
Issue: 7
Pages: 985-995
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Publication
30728336 | J:309339
 
First Author: Wang L
Year: 2019
Journal: JCI Insight
Title: Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development.
Volume: 4
Issue: 3
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Publication
24813890 | J:211797
First Author: Gonçalves GH
Year: 2014
Journal: Cell Rep
Title: Hypothalamic agouti-related peptide neurons and the central melanocortin system are crucial mediators of leptin's antidiabetic actions.
Volume: 7
Issue: 4
Pages: 1093-103
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Publication
29024666 | J:253249
First Author: Beutler LR
Year: 2017
Journal: Neuron
Title: Dynamics of Gut-Brain Communication Underlying Hunger.
Volume: 96
Issue: 2
Pages: 461-475.e5
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Publication
24011077 | J:203813
First Author: Fujikawa T
Year: 2013
Journal: Cell Metab
Title: Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin.
Volume: 18
Issue: 3
Pages: 431-44
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Publication
28135190 | J:240945
   
First Author: Adlaf EW
Year: 2017
Journal: Elife
Title: Adult-born neurons modify excitatory synaptic transmission to existing neurons.
Volume: 6
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Publication
30593498 | J:272984
First Author: Carver CM
Year: 2019
Journal: J Neurosci
Title: Gq-Coupled Muscarinic Receptor Enhancement of KCNQ2/3 Channels and Activation of TRPC Channels in Multimodal Control of Excitability in Dentate Gyrus Granule Cells.
Volume: 39
Issue: 9
Pages: 1566-1587
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Publication
35489647 | J:324814
 
First Author: Nogueira PAS
Year: 2022
Journal: Neurosci Lett
Title: The orphan receptor GPR68 is expressed in the hypothalamus and is involved in the regulation of feeding.
Volume: 781
Pages: 136660
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Publication
29914853 | J:264547
     
First Author: Rupp AC
Year: 2018
Journal: Mol Metab
Title: Specific subpopulations of hypothalamic leptin receptor-expressing neurons mediate the effects of early developmental leptin receptor deletion on energy balance.
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Publication
25187366 | J:247022
First Author: Ren H
Year: 2015
Journal: Diabetes
Title: Anorexia and impaired glucose metabolism in mice with hypothalamic ablation of Glut4 neurons.
Volume: 64
Issue: 2
Pages: 405-17
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Publication
35055102 | J:333669
 
First Author: Gönczi M
Year: 2022
Journal: Int J Mol Sci
Title: Astaxanthin Exerts Anabolic Effects via Pleiotropic Modulation of the Excitable Tissue.
Volume: 23
Issue: 2
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Publication
22325203 | J:182290
First Author: Liu T
Year: 2012
Journal: Neuron
Title: Fasting activation of AgRP neurons requires NMDA receptors and involves spinogenesis and increased excitatory tone.
Volume: 73
Issue: 3
Pages: 511-22
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Publication
22522563 | J:183754
First Author: Leshan RL
Year: 2012
Journal: Nat Med
Title: Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balance.
Volume: 18
Issue: 5
Pages: 820-3
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Publication
29940007 | J:262913
First Author: Assali DR
Year: 2018
Journal: PLoS One
Title: Food anticipatory activity on a calorie-restricted diet is independent of Sirt1.
Volume: 13
Issue: 6
Pages: e0199586
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Publication
37844254 | J:347259
First Author: Yamaguchi Y
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: An intact pituitary vasopressin system is critical for building a robust circadian clock in the suprachiasmatic nucleus.
Volume: 120
Issue: 43
Pages: e2308489120
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Publication
30635563 | J:270155
First Author: Herber CB
Year: 2019
Journal: Nat Commun
Title: Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones.
Volume: 10
Issue: 1
Pages: 163
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Publication
37468558 | J:352794
First Author: Kim SK
Year: 2023
Journal: Nat Commun
Title: Mitochondria-derived peptide SHLP2 regulates energy homeostasis through the activation of hypothalamic neurons.
Volume: 14
Issue: 1
Pages: 4321
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Publication
27015310 | J:234407
First Author: Steculorum SM
Year: 2016
Journal: Cell
Title: AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue.
Volume: 165
Issue: 1
Pages: 125-138
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Publication
35963866 | J:328782
First Author: Meier DT
Year: 2022
Journal: Nat Commun
Title: Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing.
Volume: 13
Issue: 1
Pages: 4761
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Publication
24411735 | J:220411
First Author: Wu H
Year: 2014
Journal: Neuron
Title: Cellular resolution maps of X chromosome inactivation: implications for neural development, function, and disease.
Volume: 81
Issue: 1
Pages: 103-19
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Publication
39627537 | J:361479
First Author: Wang H
Year: 2025
Journal: Nat Neurosci
Title: Parallel gut-to-brain pathways orchestrate feeding behaviors.
Volume: 28
Issue: 2
Pages: 320-335
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HT Experiment
GSE68177 | Cell type transcriptomics of hypothalamic energy-sensing neuron responses to fasting
Series Id: E-GEOD-68177
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
37031230 | J:352454
First Author: Park JW
Year: 2023
Journal: Nat Commun
Title: Circulating blood eNAMPT drives the circadian rhythms in locomotor activity and energy expenditure.
Volume: 14
Issue: 1
Pages: 1994
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Publication
32386544 | J:347445
First Author: Wang Q
Year: 2020
Journal: Cell
Title: The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas.
Volume: 181
Issue: 4
Pages: 936-953.e20
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Transgene
MGI:3640615 | Tg(Pomc1-cre)16Lowl
Type: transgene
Organism: mouse, laboratory
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Publication
36323255 | J:333430
First Author: Ju SH
Year: 2022
Journal: Cell Rep
Title: Melanocortin-4 receptors activate sympathetic preganglionic neurons and elevate blood pressure via TRPV1.
Volume: 41
Issue: 5
Pages: 111579
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HT Experiment
GSE208355 | HypoMap - a unified single cell gene expression atlas of the murine hypothalamus
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
24990862 | -
First Author: Guan X
Year: 2014
Journal: Am J Physiol Regul Integr Comp Physiol
Title: The CNS glucagon-like peptide-2 receptor in the control of energy balance and glucose homeostasis.
Volume: 307
Issue: 6
Pages: R585-96
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Publication
16401478 | -
First Author: Guan X
Year: 2006
Journal: Gastroenterology
Title: GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow.
Volume: 130
Issue: 1
Pages: 150-64
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Publication
10982769 | -
First Author: Yusta B
Year: 2000
Journal: Gastroenterology
Title: Enteroendocrine localization of GLP-2 receptor expression in humans and rodents.
Volume: 119
Issue: 3
Pages: 744-55
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Publication
19920220 | -
First Author: Wang Y
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: GLP-2 potentiates L-type Ca2+ channel activity associated with stimulated glucose uptake in hippocampal neurons.
Volume: 298
Issue: 2
Pages: E156-66
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Protein Domain
IPR039125 | GLP2R
Type: Family
Description: Glucagon-like peptide 2 (GLP2) acts through G protein-coupled receptor GLP2R and plays a physiological role in the control of food intake and glucose homeostasis. It promotes intestinal epithelial homeostasis and function, enhances intestinal nutrient absorption and blood flow and assists gut immune defense []. GLP2R is not only expressed in nutrient-sensing endocrine cells (such as enteroendocrine cells and pancreatic alpha-cells), but also in neurons [, , ]. GLP2R in hypothalamic POMC neurons is required for promoting hepatic insulin sensitivity and glycemic control. Through GLP2R-p85alpha interaction, GLP2 activates PI3K-Akt-FoxO1 signaling in POMC neurons [].
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Allele
Tg(Pomc-rtTA)1Rck | MGI:3785562
Name: transgene insertion 1, Jeffrey M Friedman
Allele Type: Transgenic
Attribute String: Transactivator
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Allele
Tg(Rr594-EGFP)#Mrub | MGI:7852716
Name: transgene insertion, Marcelo Rubinstein
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Publication
34676208 | J:312487
 
First Author: Zhang X
Year: 2021
Journal: Front Cell Dev Biol
Title: Trilogy Development of Proopiomelanocortin Neurons From Embryonic to Adult Stages in the Mice Retina.
Volume: 9
Pages: 718851
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Publication
21211522 | J:175590
First Author: de Souza FS
Year: 2011
Journal: Eur J Pharmacol
Title: The estrogen receptor α colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2.
Volume: 660
Issue: 1
Pages: 181-7
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Publication
15056704 | J:256831
First Author: Overstreet LS
Year: 2004
Journal: J Neurosci
Title: A transgenic marker for newly born granule cells in dentate gyrus.
Volume: 24
Issue: 13
Pages: 3251-9
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Publication
31301366 | J:282993
 
First Author: Wei K
Year: 2019
Journal: Neuroscience
Title: Defining the Vulnerability Window of Anesthesia-Induced Neuroapoptosis in Developing Dentate Gyrus Granule Cells - A Transgenic Approach Utilizing POMC-EGFP Mice.
Volume: 415
Pages: 59-69
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Publication
35902579 | J:327119
First Author: Ávalos Y
Year: 2022
Journal: Cell Death Dis
Title: Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism.
Volume: 13
Issue: 7
Pages: 659
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Publication
29165691 | J:255597
First Author: Qiu J
Year: 2018
Journal: Endocrinology
Title: Estradiol Protects Proopiomelanocortin Neurons Against Insulin Resistance.
Volume: 159
Issue: 2
Pages: 647-664
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Publication
34177455 | J:353229
 
First Author: Perissinotti PP
Year: 2021
Journal: Front Neurosci
Title: TRPC1/5-Ca (V) 3 Complex Mediates Leptin-Induced Excitability in Hypothalamic Neurons.
Volume: 15
Pages: 679078
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HT Experiment
E-GEOD-38672 | Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to neurodegeneration and development of obesity
Series Id: GSE38672
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Tg(Pomc-EGFP)1Low | MGI:3776091
Name: transgene insertion 1, Malcolm J Low
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:3785812 | FVB-Tg(Pomc-rtTA)1Rck/J
Attribute String: coisogenic, transgenic
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Strain
MGI:3785838 | FVB-Tg(Pomc-rtTA)1Rck
Attribute String: transgenic
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Allele
Tg(Eno2-Pomc)1Mobb | MGI:4420545
Name: transgene insertion 1, Charles V Mobbs
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Pomc*-cre)#Jdr | MGI:6201724
Name: transgene insertion, Jaques Drouin
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Rr279<tm1.1Low> | MGI:7853955
Name: regulatory region 279; targeted mutation 1.1, Malcolm J Low
Allele Type: Targeted
Attribute String: Modified regulatory region
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Allele
Rr280<tm1.1Low> | MGI:7853956
Name: regulatory region 280; targeted mutation 1.1, Malcolm J Low
Allele Type: Targeted
Attribute String: Modified regulatory region
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Genotype
Genotype
Symbol: Tg(Pomc-rtTA)1Rck/?
Background: FVB-Tg(Pomc-rtTA)1Rck
Zygosity: ot
Has Mutant Allele: true
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Publication
25926624 | J:223804
First Author: Pravdivyi I
Year: 2015
Journal: Hum Mol Genet
Title: Progressive postnatal decline in leptin sensitivity of arcuate hypothalamic neurons in the Magel2-null mouse model of Prader-Willi syndrome.
Volume: 24
Issue: 15
Pages: 4276-83
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