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Search results 1201 to 1300 out of 1588 for Sftpc

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Type Details Score
Allele
Tg(Sftpc-Nmyc1/EGFP)1Blh | MGI:3574950
Name: transgene insertion 1, Brigid L Hogan
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Sftpc<em1(cre/ERT2)Smoc> | MGI:6758051
Name: surfactant associated protein C; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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Allele
Sftpc<em3Smoc> | MGI:7266381
Name: surfactant associated protein C; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6354510 | C57BL/6JSmoc-Sftpc<em1(cre/ERT2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Sftpc<em2Smoc> | MGI:7266380
Name: surfactant associated protein C; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Epitope tag, Reporter
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Strain
MGI:6355175 | C57BL/6JSmoc-Sftpc<em2Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6476252 | C57BL/6JSmoc-Sftpc<em3Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Tg(Sftpc-Nmyc1/EGFP)1Blh/?
Background: involves: C57BL/6 * DBA
Zygosity: ot
Has Mutant Allele: true
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Publication
21670280 | J:173548
First Author: Lawson WE
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs.
Volume: 108
Issue: 26
Pages: 10562-7
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Allele
Tg(SFTPC-TAg)5.1Jaw | MGI:3040278
Name: transgene insertion 5.1, Jeffrey A Whitsett
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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HT Experiment
GSE155814 | Expression of a surfactant protein C mutation links postnatal type 2 cell dysfunction with adult disease
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
24213573 | J:216273
First Author: Wang IC
Year: 2014
Journal: Oncogene
Title: Foxm1 transcription factor is required for the initiation of lung tumorigenesis by oncogenic Kras(G12D.).
Volume: 33
Issue: 46
Pages: 5391-6
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Allele
Tg(SFTPC-TGFA)1Kor | MGI:2389218
Name: transgene insertion 1, Thomas R Korfhagen
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(SFTPC-RAF1)87Urr | MGI:2447566
Name: transgene insertion 87, Ulf R Rapp
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
1394139 | J:70783
First Author: Wikenheiser KA
Year: 1992
Journal: Cancer Res
Title: Simian virus 40 large T antigen directed by transcriptional elements of the human surfactant protein C gene produces pulmonary adenocarcinomas in transgenic mice.
Volume: 52
Issue: 19
Pages: 5342-52
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Publication
9191473 | J:41560
First Author: Wikenheiser KA
Year: 1997
Journal: Am J Respir Cell Mol Biol
Title: Tumor progression and cellular differentiation of pulmonary adenocarcinomas in SV40 large T antigen transgenic mice.
Volume: 16
Issue: 6
Pages: 713-23
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Allele
Tg(Sftpc-cre)1Blh | MGI:3574949
Name: transgene insertion 1, Brigid L Hogan
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(SFTPC-ITGB6)1Des | MGI:3832271
Name: transgene insertion 1, Dean Sheppard
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Sftpc<tm1.1(cre/ERT2)Ptch> | MGI:5485991
Name: surfactant associated protein C; targeted mutation 1.1, Pao-Tien Chuang
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Protein
Q8R2N0
Organism: Mus musculus/domesticus
Length: 240  
Fragment?: false
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Publication
12882447 | -
First Author: Yang MC
Year: 2003
Journal: Eur Respir J
Title: BR22, a 26 kDa thyroid transcription factor-1 associated protein (TAP26), is expressed in human lung cells.
Volume: 22
Issue: 1
Pages: 28-34
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Publication
16630564 | -
First Author: Yang MC
Year: 2006
Journal: Biochem Biophys Res Commun
Title: The TTF-1/TAP26 complex differentially modulates surfactant protein-B (SP-B) and -C (SP-C) promoters in lung cells.
Volume: 344
Issue: 2
Pages: 484-90
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Protein Domain
IPR013730 | Fyv7/TAP26
Type: Family
Description: This entry include proteins from the FYV7 and the TAP26 families []. FYV7 is involved in the processing of 20S pre-rRNA during the maturation of SSU-rRNA from tricistronic RNA transcripts (SSU-rRNA, 5.8S rRNA, LSU-rRNA). The SSU (small subunit) processome is required for production of the small ribosomal subunit RNA, the 18S rRNA []. Fyv7 may also be required for survival upon K1 Killer toxin exposure.Thyroid transcription factor 1-associated protein 26 (TAP26, also known as BR22) is a component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC). It enhances homeobox protein Nkx-2.1-activated SFTPB and SFTPC promoter activities [, ].
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Publication
33740186 | J:335291
First Author: Pang Q
Year: 2022
Journal: Sci China Life Sci
Title: GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.
Volume: 65
Issue: 1
Pages: 193-205
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Publication
8163670 | J:79837
First Author: Korfhagen TR
Year: 1994
Journal: J Clin Invest
Title: Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice.
Volume: 93
Issue: 4
Pages: 1691-9
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Publication
11597899 | J:72565
First Author: Hardie WD
Year: 2001
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Dose-dependent lung remodeling in transgenic mice expressing transforming growth factor-alpha.
Volume: 281
Issue: 5
Pages: L1088-94
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Publication
12896876 | J:86541
First Author: Le Cras TD
Year: 2003
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Disrupted pulmonary vascular development and pulmonary hypertension in transgenic mice overexpressing transforming growth factor-alpha.
Volume: 285
Issue: 5
Pages: L1046-54
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Publication
11717240 | J:135119
First Author: Pillow JJ
Year: 2001
Journal: J Appl Physiol (1985)
Title: Overexpression of TGF-alpha increases lung tissue hysteresivity in transgenic mice.
Volume: 91
Issue: 6
Pages: 2730-4
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Publication
9327741 | J:80004
First Author: Hardie WD
Year: 1997
Journal: Am J Pathol
Title: Postnatal lung function and morphology in transgenic mice expressing transforming growth factor-alpha.
Volume: 151
Issue: 4
Pages: 1075-83
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Allele
Tg(SFTPC-MST1R)71Mhw | MGI:2446031
Name: transgene insertion 71, Ming-Hai Wang
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(SFTPC-rtTA)5Jaw | MGI:2445716
Name: transgene insertion 5, Jeffrey A Whitsett
Allele Type: Transgenic
Attribute String: Transactivator
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Publication
22815814 | J:189615
First Author: Londhe KB
Year: 2012
Journal: PLoS One
Title: A cross-platform comparison of genome-wide expression changes of laser microdissected lung tissue of C-Raf transgenic mice using 3'IVT and exon array.
Volume: 7
Issue: 7
Pages: e40778
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Allele
Tg(SFTPC-EML4/ALK)502-4Hima | MGI:3834680
Name: transgene insertion 502-4, Hiroyuki Mano
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(SFTPC-cre)#Mliu | MGI:4440739
Name: transgene insertion, Mingyao Liu
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(SFTPC-TGFA)28Kor | MGI:4819387
Name: transgene insertion 28, Thomas R Korfhagen
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(SFTPC-rtTA)2Jaw | MGI:5000438
Name: transgene insertion 2, Jeffrey A Whitsett
Allele Type: Transgenic
Attribute String: Transactivator
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Allele
Tg(SFTPC-Fstl1)2Ning | MGI:6188877
Name: transgene insertion 2, Wen Ning
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Sftpc<tm1(dre/ERT2)Bzsh> | MGI:6357171
Name: surfactant associated protein C; targeted mutation 1, Bin Zhou
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Allele
Tg(SFTPC-SFTPA1*)T2Jflo | MGI:7365194
Name: transgene insertion T2, Joanna Floros
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(SFTPC-SFTPA2*)T1Jflo | MGI:7365225
Name: transgene insertion T1, Joanna Floros
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(SFTPC-SFTPA1*)T1Jflo | MGI:7365197
Name: transgene insertion T1, Joanna Floros
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(SFTPC-SFTPA2*)T10Jflo | MGI:7365216
Name: transgene insertion T10, Joanna Floros
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(SFTPC-SFTPA2*)T4Jflo | MGI:7493599
Name: transgene insertion T4, Joanna Floros
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(SFTPC-SFTPA1*)T4Jflo | MGI:7493645
Name: transgene insertion T4, Joanna Floros
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(SFTPC-SFTPA1*)T3Jflo | MGI:7493729
Name: transgene insertion T3, Joanna Floros
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(SFTPC-RAF1)87Urr/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(SFTPC-ITGB6)1Des/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Sftpc-cre)1Blh/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Publication
26869074 | J:231302
First Author: Ustiyan V
Year: 2016
Journal: Dev Dyn
Title: β-catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesis.
Volume: 245
Issue: 5
Pages: 590-604
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Publication
23867472 | J:204282
First Author: Yin Y
Year: 2013
Journal: Cancer Res
Title: Rapid induction of lung adenocarcinoma by fibroblast growth factor 9 signaling through FGF receptor 3.
Volume: 73
Issue: 18
Pages: 5730-41
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Publication
16055670 | J:132772
First Author: Perl AK
Year: 2005
Journal: Am J Respir Cell Mol Biol
Title: Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli.
Volume: 33
Issue: 5
Pages: 455-62
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Publication
9761761 | J:51592
First Author: Huang X
Year: 1998
Journal: Am J Respir Cell Mol Biol
Title: Expression of the human integrin beta6 subunit in alveolar type II cells and bronchiolar epithelial cells reverses lung inflammation in beta6 knockout mice.
Volume: 19
Issue: 4
Pages: 636-42
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Publication
11954676 | J:76106
 
First Author: Leikauf GD
Year: 2001
Journal: Res Rep Health Eff Inst
Title: Pathogenomic mechanisms for particulate matter induction of acute lung injury and inflammation in mice.
Issue: 105
Pages: 5-58; discussion 59-71
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Allele
Tg(SFTPC-FGFR2)1Lwi | MGI:2385682
Name: transgene insertion 1, Lewis Williams
Allele Type: Transgenic
Attribute String: Dominant negative, Inserted expressed sequence
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Publication
12214279 | J:79080
First Author: Chen YQ
Year: 2002
Journal: Oncogene
Title: Targeted expression of the receptor tyrosine kinase RON in distal lung epithelial cells results in multiple tumor formation: oncogenic potential of RON in vivo.
Volume: 21
Issue: 41
Pages: 6382-6
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Strain
MGI:3767668 | B6.Cg-Tg(SFTPC-rtTA)5Jaw/J
Attribute String: mutant strain, transgenic
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Strain
MGI:3654755 | FVB.Cg-Tg(SFTPC-rtTA)5Jaw/J
Attribute String: transgenic, mutant strain, congenic
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Strain
MGI:3760165 | C.Cg-Tg(SFTPC-rtTA)5Jaw/J
Attribute String: congenic, mutant strain, transgenic
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Publication
22298531 | J:191907
First Author: Huang Y
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Hypoxia-inducible factor 2α plays a critical role in the formation of alveoli and surfactant.
Volume: 46
Issue: 2
Pages: 224-32
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Publication
25210856 | J:222520
First Author: Kapere Ochieng J
Year: 2014
Journal: PLoS One
Title: Differentiated type II pneumocytes can be reprogrammed by ectopic Sox2 expression.
Volume: 9
Issue: 9
Pages: e107248
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Publication
21189286 | J:169183
First Author: Ikeda H
Year: 2011
Journal: Mol Cell Biol
Title: Increased Akt-mTOR signaling in lung epithelium is associated with respiratory distress syndrome in mice.
Volume: 31
Issue: 5
Pages: 1054-65
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Publication
22094019 | J:180152
First Author: Bridges JP
Year: 2012
Journal: Dev Biol
Title: Conditional hypoxia inducible factor-1α induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis.
Volume: 362
Issue: 1
Pages: 24-41
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Publication
24669837 | J:232238
First Author: Ochieng JK
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: Sox2 regulates the emergence of lung basal cells by directly activating the transcription of Trp63.
Volume: 51
Issue: 2
Pages: 311-22
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Publication
25904058 | J:223330
First Author: Londhe VA
Year: 2015
Journal: Dev Dyn
Title: Overexpression of LINCR in the developing mouse lung epithelium inhibits distal differentiation and induces cystic changes.
Volume: 244
Issue: 7
Pages: 827-38
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Publication
18635814 | J:155786
First Author: Minowada G
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: Overexpression of Sprouty 2 in mouse lung epithelium inhibits urethane-induced tumorigenesis.
Volume: 40
Issue: 1
Pages: 31-7
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Publication
26545899 | J:233195
First Author: Winters CJ
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: CaMKII inhibition in type II pneumocytes protects from bleomycin-induced pulmonary fibrosis by preventing Ca2+-dependent apoptosis.
Volume: 310
Issue: 1
Pages: L86-94
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Publication
16239640 | J:120191
First Author: Park KS
Year: 2006
Journal: Am J Respir Cell Mol Biol
Title: Transdifferentiation of ciliated cells during repair of the respiratory epithelium.
Volume: 34
Issue: 2
Pages: 151-7
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Publication
17018522 | J:117640
First Author: Xu J
Year: 2006
Journal: J Biol Chem
Title: Stage-specific effects of cAMP signaling during distal lung epithelial development.
Volume: 281
Issue: 50
Pages: 38894-904
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Allele
Tg(SFTPC-RAF1-BxB)1Urr | MGI:2447567
Name: transgene insertion 1, Ulf R Rapp
Allele Type: Transgenic
Attribute String: Constitutively active, Humanized sequence, Inserted expressed sequence
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Publication
29109255 | J:254318
First Author: Magnani ND
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.
Volume: 114
Issue: 47
Pages: E10178-E10186
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Publication
35935956 | J:327602
 
First Author: Wang J
Year: 2022
Journal: Front Immunol
Title: Type II alveolar epithelial cell aryl hydrocarbon receptor protects against allergic airway inflammation through controlling cell autophagy.
Volume: 13
Pages: 964575
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Publication
33187989 | J:317163
 
First Author: Kellar GG
Year: 2021
Journal: J Biol Chem
Title: Loss of versican and production of hyaluronan in lung epithelial cells are associated with airway inflammation during RSV infection.
Volume: 296
Pages: 100076
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Publication
19064915 | J:142679
First Author: Soda M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A mouse model for EML4-ALK-positive lung cancer.
Volume: 105
Issue: 50
Pages: 19893-7
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Publication
29775614 | J:272477
First Author: Kotani N
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Tumor-dependent secretion of close homolog of L1 results in elevation of its circulating level in mouse model for human lung tumor.
Volume: 501
Issue: 4
Pages: 982-987
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Publication
11919079 | J:133163
First Author: Hardie WD
Year: 2002
Journal: Am J Respir Cell Mol Biol
Title: Dose-related protection from nickel-induced lung injury in transgenic mice expressing human transforming growth factor-alpha.
Volume: 26
Issue: 4
Pages: 430-7
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Strain
MGI:5301893 | STOCK Tg(SFTPC-rtTA)2Jaw/J
Attribute String: mutant stock, transgenic
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Allele
Tg(Sftpc-rtTA,Nudt18-tetO-cre)1Ptch | MGI:5486022
Name: transgene insertion 1, Pao-Tien Chuang
Allele Type: Transgenic
Attribute String: Inducible, Recombinase, Transactivator
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Allele
Tg(SFTPC-Tnf)2Pva | MGI:5644302
Name: transgene insertion 2, Pierre Vassalli
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6194210 | B6.Cg-Tg(SFTPC-Tnf)2Pva/LzuoJ
Attribute String: congenic, mutant strain, transgenic
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Publication
7542280 | J:28120
First Author: Miyazaki Y
Year: 1995
Journal: J Clin Invest
Title: Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis.
Volume: 96
Issue: 1
Pages: 250-9
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Publication
27875656 | J:257657
First Author: Eurlings IM
Year: 2017
Journal: Am J Respir Cell Mol Biol
Title: Involvement of c-Jun N-Terminal Kinase in TNF-α-Driven Remodeling.
Volume: 56
Issue: 3
Pages: 393-401
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Publication
25106431 | J:222067
First Author: Eurlings IM
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.
Volume: 307
Issue: 7
Pages: L557-65
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Publication
31426531 | J:290336
 
First Author: Yamaoka T
Year: 2019
Journal: Int J Mol Sci
Title: Blockade of EGFR Activation Promotes TNF-Induced Lung Epithelial Cell Apoptosis and Pulmonary Injury.
Volume: 20
Issue: 16
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Allele
Tg(Sftpc,-EGFP)1Dobb | MGI:5696989
Name: transgene insertion 1, Leland Dobbs
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:7606178 | STOCK Sftpc<tm1(dre/ERT2)Bzsh>/J
Attribute String: targeted mutation, mutant stock
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Allele
Sftpc<tm1.1(Nicre)Thbr> | MGI:7263083
Name: surfactant associated protein C; targeted mutation 1.1, Thomas Braun
Allele Type: Targeted
Attribute String: Epitope tag, Recombinase, Reporter
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Allele
Sftpc<tm2.1(NtTA)Thbr> | MGI:7263085
Name: surfactant associated protein C; targeted mutation 2.1, Thomas Braun
Allele Type: Targeted
Attribute String: Epitope tag, Reporter, Transactivator
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Genotype
Genotype
Symbol: Tg(SFTPC-MST1R)71Mhw/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Itgb6/Itgb6 Tg(SFTPC-ITGB6)1Des/?
Background: involves: 129S4/SvJae * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(SFTPC-EML4/ALK)502-4Hima/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr2/Fgfr2 Tg(Sftpc-cre)1Blh/?
Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(SFTPC-rtTA)5Jaw/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(SFTPC-Tnf)2Pva/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Adora2b/Adora2b Tg(Sftpc-cre)1Blh/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hspa5/Hspa5 Tg(Sftpc-cre)1Blh/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hspa5/Hspa5 Tg(Sftpc-cre)1Blh/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * ICR
Zygosity: cn
Has Mutant Allele: true
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Publication
19497281 | J:149822
First Author: Rawlins EL
Year: 2009
Journal: Cell Stem Cell
Title: The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium.
Volume: 4
Issue: 6
Pages: 525-34
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Publication
29464089 | J:309220
First Author: Thakur C
Year: 2018
Journal: Oncotarget
Title: Cysts mark the early stage of metastatic tumor development in non-small cell lung cancer.
Volume: 9
Issue: 5
Pages: 6518-6535
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Publication
12242301 | -
First Author: Wehner KA
Year: 2002
Journal: Mol Cell Biol
Title: Components of an interdependent unit within the SSU processome regulate and mediate its activity.
Volume: 22
Issue: 20
Pages: 7258-67
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Publication
18192501 | J:149718
First Author: Quinton LJ
Year: 2008
Journal: Am J Respir Cell Mol Biol
Title: Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during Escherichia coli pneumonia.
Volume: 38
Issue: 6
Pages: 699-706
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