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Search results 1201 to 1300 out of 1661 for Stat1

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Type Details Score
Publication
16118227 | -
First Author: Sun XJ
Year: 2005
Journal: J Biol Chem
Title: Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase.
Volume: 280
Issue: 42
Pages: 35261-71
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Protein Domain
IPR042294 | SETD2_animal
Type: Family
Description: SETD2 is a histone methyltransferase that specifically trimethylates 'Lys-36' of histone H3 (H3K36me3) using dimethylated 'Lys-36' (H3K36me2) as substrate [, ]. It is required for DNA double-strand break repair and activation of the p53-mediated checkpoint []. SETD2-inactivation has been linked to tumour development []. SETD2 also methylates alpha-tubulin at lysine 40, the same lysine that is marked by acetylation on microtubules. Methylation of microtubules occurs during mitosis and cytokinesis and can be ablated by SETD2 deletion, which causes mitotic spindle and cytokinesis defects, micronuclei, and polyploidy []. Moreover, SETD2 is also involved in interferon-alpha-induced antiviral defense by mediating both monomethylation of STAT1 at 'Lys-525' and catalyzing H3K36me3 on promoters of some interferon-stimulated genes (ISGs) to activate gene transcription [].
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Publication
23986597 | J:203928
First Author: Hua L
Year: 2013
Journal: J Virol
Title: Cytokine-dependent induction of CD4+ T cells with cytotoxic potential during influenza virus infection.
Volume: 87
Issue: 21
Pages: 11884-93
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GO Term
GO:0042532 | negative regulation of tyrosine phosphorylation of STAT protein
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Publication
27518565 | J:236080
First Author: Park IY
Year: 2016
Journal: Cell
Title: Dual Chromatin and Cytoskeletal Remodeling by SETD2.
Volume: 166
Issue: 4
Pages: 950-962
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Publication
19141475 | J:200392
First Author: Yoh SM
Year: 2008
Journal: Genes Dev
Title: The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation.
Volume: 22
Issue: 24
Pages: 3422-34
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Publication
24843002 | -
 
First Author: Carvalho S
Year: 2014
Journal: Elife
Title: SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint.
Volume: 3
Pages: e02482
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Publication
27191891 | -
First Author: Li J
Year: 2016
Journal: Oncotarget
Title: SETD2: an epigenetic modifier with tumor suppressor functionality.
Volume: 7
Issue: 31
Pages: 50719-50734
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Publication
8848048 | -
First Author: Bhattacharya S
Year: 1996
Journal: Nature
Title: Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha.
Volume: 383
Issue: 6598
Pages: 344-7
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Publication
22914091 | -
First Author: Venkatesh S
Year: 2012
Journal: Nature
Title: Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes.
Volume: 489
Issue: 7416
Pages: 452-5
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Publication
28256625 | -
 
First Author: Zhang Y
Year: 2017
Journal: Sci Rep
Title: Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation.
Volume: 7
Pages: 43906
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Publication
27317772 | -
First Author: Tlemsani C
Year: 2016
Journal: J Med Genet
Title: SETD2 and DNMT3A screen in the Sotos-like syndrome French cohort.
Volume: 53
Issue: 11
Pages: 743-751
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Publication
24509477 | J:258985
First Author: Zhu X
Year: 2014
Journal: Nat Genet
Title: Identification of functional cooperative mutations of SETD2 in human acute leukemia.
Volume: 46
Issue: 3
Pages: 287-93
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Publication
24662245 | -
 
First Author: Mar BG
Year: 2014
Journal: Nat Commun
Title: Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia.
Volume: 5
Pages: 3469
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Publication
20054297 | -
First Author: Dalgliesh GL
Year: 2010
Journal: Nature
Title: Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.
Volume: 463
Issue: 7279
Pages: 360-3
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Publication
19915673 | -
First Author: Grini PE
Year: 2009
Journal: PLoS One
Title: The ASH1 HOMOLOG 2 (ASHH2) histone H3 methyltransferase is required for ovule and anther development in Arabidopsis.
Volume: 4
Issue: 11
Pages: e7817
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Protein Domain
IPR035854 | STAT2_SH2
Type: Domain
Description: STAT2 is a member of the STAT protein family. In response to interferon, STAT2 forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly []. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with STAT2, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus []. This entry represents the SH2 domain of STAT2.STAT proteins have a dual function: signal transduction and activation of transcription. When cytokines are bound to cell surface receptors, the associated Janus kinases (JAKs) are activated, leading to tyrosine phosphorylation of the given STAT proteins []. Phosphorylated STATs form dimers, translocate to the nucleus, and bind specific response elements to activate transcription of target genes []. STAT proteins contain an N-terminal domain (NTD), a coiled-coil domain (CCD), a DNA-binding domain (DBD), an α-helical linker domain (LD), an SH2 domain, and a transactivation domain (TAD). The SH2 domain is necessary for receptor association and tyrosine phosphodimer formation. There are seven mammalian STAT family members which have been identified: STAT1, STAT2, STAT3, STAT4, STAT5 (STAT5A and STAT5B), and STAT6 [].
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Protein Domain
IPR044437 | SETD2/Set2_SET
Type: Domain
Description: This entry represents the SET domain found in SETD2 from animals, ASHH2 from plants and Set2 from fungi. Proteins containing this domain are a group of histone methyltransferases that methylates histone H3 to form H3K36me [, ].Yeast Set2 is involved in transcription elongation as well as in transcription repression []. The methyltransferase activity of budding yeast Set2 requires the recruitment to the RNA polymerase II, which is CTK1 dependent [, , , , , , ]. Plant ASHH2 is required for the correct expression of genes essential to reproductive development [].SETD2 acts as histone-lysine N-methyltransferase that specifically trimethylates 'Lys-36' of histone H3 (H3K36me3) using demethylated 'Lys-36' (H3K36me2) as substrate [, ]. SETD2 is also required for DNA double-strand break repair and activation of the p53-mediated checkpoint []. SETD2-inactivation has been linked to tumour development []. SETD2 also methylates alpha-tubulin at lysine 40, the same lysine that is marked by acetylation on microtubules. Methylation of microtubules occurs during mitosis and cytokinesis and can be ablated by SETD2 deletion, which causes mitotic spindle and cytokinesis defects, micronuclei, and polyploidy []. Moreover, SETD2 is also involved in interferon-alpha-induced antiviral defense by mediating both monomethylation of STAT1 at 'Lys-525' and catalyzing H3K36me3 on promoters of some interferon-stimulated genes (ISGs) to activate gene transcription [].SETD2 has been linked to several human diseases, including Renal cell carcinoma (RCC) [], Luscan-Lumish syndrome (LLS) [], Leukemia, acute lymphoblastic (ALL) []and Leukemia, acute myelogenous (AML) [, ].
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GO Term
GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein
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Publication
29746837 | J:261503
First Author: Gorman MJ
Year: 2018
Journal: Cell Host Microbe
Title: An Immunocompetent Mouse Model of Zika Virus Infection.
Volume: 23
Issue: 5
Pages: 672-685.e6
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Publication
30517866 | J:269925
First Author: Uccellini MB
Year: 2018
Journal: Cell Rep
Title: ISRE-Reporter Mouse Reveals High Basal and Induced Type I IFN Responses in Inflammatory Monocytes.
Volume: 25
Issue: 10
Pages: 2784-2796.e3
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Publication
33125053 | J:307787
 
First Author: Zhang L
Year: 2021
Journal: J Exp Med
Title: Type I interferon signaling mediates Mycobacterium tuberculosis-induced macrophage death.
Volume: 218
Issue: 2
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Publication
16537510 | J:107585
First Author: Goenka S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Selective potentiation of Stat-dependent gene expression by collaborator of Stat6 (CoaSt6), a transcriptional cofactor.
Volume: 103
Issue: 11
Pages: 4210-5
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Publication
9388184 | J:52872
First Author: Chung CD
Year: 1997
Journal: Science
Title: Specific inhibition of Stat3 signal transduction by PIAS3.
Volume: 278
Issue: 5344
Pages: 1803-5
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Publication
12600939 | J:119425
First Author: Malakhova OA
Year: 2003
Journal: Genes Dev
Title: Protein ISGylation modulates the JAK-STAT signaling pathway.
Volume: 17
Issue: 4
Pages: 455-60
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Publication
9240457 | J:41984
First Author: Piekorz RP
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Members of the family of IL-6-type cytokines activate Stat5a in various cell types.
Volume: 236
Issue: 2
Pages: 438-43
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Publication
18292493 | J:131731
First Author: Batten M
Year: 2008
Journal: J Immunol
Title: Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells.
Volume: 180
Issue: 5
Pages: 2752-6
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Publication
25972481 | J:323841
First Author: Yamashita-Kanemaru Y
Year: 2015
Journal: J Immunol
Title: CD155 (PVR/Necl5) mediates a costimulatory signal in CD4+ T cells and regulates allergic inflammation.
Volume: 194
Issue: 12
Pages: 5644-53
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Publication
27701741 | J:252157
First Author: Jiang L
Year: 2016
Journal: Eur J Immunol
Title: Type I IFN signaling facilitates the development of IL-10-producing effector CD8+ T cells during murine influenza virus infection.
Volume: 46
Issue: 12
Pages: 2778-2788
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Publication
37884352 | J:342113
     
First Author: Chiriac MT
Year: 2023
Journal: Gut
Title: IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling.
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Publication
16906166 | J:112649
First Author: Stumhofer JS
Year: 2006
Journal: Nat Immunol
Title: Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system.
Volume: 7
Issue: 9
Pages: 937-45
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Publication
12754505 | J:83645
First Author: Croker BA
Year: 2003
Journal: Nat Immunol
Title: SOCS3 negatively regulates IL-6 signaling in vivo.
Volume: 4
Issue: 6
Pages: 540-5
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Publication
25848864 | J:231858
First Author: Ramirez-Ortiz ZG
Year: 2015
Journal: Nat Immunol
Title: The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity.
Volume: 16
Issue: 5
Pages: 495-504
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Publication
39168127 | J:353957
     
First Author: Cordeiro B
Year: 2024
Journal: Cell Metab
Title: Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females.
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Publication
37355989 | J:337913
First Author: Xiao Z
Year: 2023
Journal: Cell Rep
Title: METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells.
Volume: 42
Issue: 7
Pages: 112684
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Publication
38833371 | J:352683
First Author: Purbey PK
Year: 2024
Journal: Cell Rep
Title: Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity.
Volume: 43
Issue: 6
Pages: 114289
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Publication
27043411 | J:259593
First Author: Xing Y
Year: 2016
Journal: Nat Immunol
Title: Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signaling.
Volume: 17
Issue: 5
Pages: 565-73
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Publication
18178806 | J:130953
First Author: Mayer KD
Year: 2008
Journal: J Immunol
Title: Cutting edge: T-bet and IL-27R are critical for in vivo IFN-gamma production by CD8 T cells during infection.
Volume: 180
Issue: 2
Pages: 693-7
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Publication
16311601 | J:112593
First Author: Fenner JE
Year: 2006
Journal: Nat Immunol
Title: Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity.
Volume: 7
Issue: 1
Pages: 33-9
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Publication
24412616 | J:209391
First Author: Fielding CA
Year: 2014
Journal: Immunity
Title: Interleukin-6 signaling drives fibrosis in unresolved inflammation.
Volume: 40
Issue: 1
Pages: 40-50
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Publication
23542035 | J:197246
First Author: Pattison MJ
Year: 2013
Journal: FEBS Lett
Title: IFNβ autocrine feedback is required to sustain TLR induced production of MCP-1 in macrophages.
Volume: 587
Issue: 10
Pages: 1496-503
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Publication
24973819 | J:259007
First Author: Végran F
Year: 2014
Journal: Nat Immunol
Title: The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells.
Volume: 15
Issue: 8
Pages: 758-66
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Publication
31471108 | J:283546
First Author: Forero A
Year: 2019
Journal: Immunity
Title: Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and Type III Interferons.
Volume: 51
Issue: 3
Pages: 451-464.e6
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Publication
18549798 | J:137735
First Author: Shi M
Year: 2008
Journal: Immunity
Title: Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation.
Volume: 28
Issue: 6
Pages: 763-73
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Publication
23999498 | J:202844
First Author: Kreutzfeldt M
Year: 2013
Journal: J Exp Med
Title: Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss.
Volume: 210
Issue: 10
Pages: 2087-103
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Publication
36917954 | J:335714
First Author: Klement JD
Year: 2023
Journal: Cancer Cell
Title: Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment.
Volume: 41
Issue: 3
Pages: 620-636.e9
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Publication
20693420 | J:163843
First Author: Richer E
Year: 2010
Journal: J Immunol
Title: N-ethyl-N-nitrosourea-induced mutation in ubiquitin-specific peptidase 18 causes hyperactivation of IFN-αß signaling and suppresses STAT4-induced IFN-γ production, resulting in increased susceptibility to Salmonella typhimurium.
Volume: 185
Issue: 6
Pages: 3593-601
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Publication
37352855 | J:338214
First Author: Lei Y
Year: 2023
Journal: Cell
Title: Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Volume: 186
Issue: 14
Pages: 3013-3032.e22
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27216180 | J:232703
First Author: Su X
Year: 2016
Journal: Cancer Res
Title: Antagonizing Integrin β3 Increases Immunosuppression in Cancer.
Volume: 76
Issue: 12
Pages: 3484-95
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Publication
30355616 | J:269099
First Author: Disson O
Year: 2018
Journal: J Exp Med
Title: Peyer's patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion.
Volume: 215
Issue: 11
Pages: 2936-2954
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Publication
24726362 | J:211814
First Author: Forys JT
Year: 2014
Journal: Cell Rep
Title: ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis.
Volume: 7
Issue: 2
Pages: 514-26
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Publication
25896511 | J:222614
First Author: Goldmann T
Year: 2015
Journal: EMBO J
Title: USP18 lack in microglia causes destructive interferonopathy of the mouse brain.
Volume: 34
Issue: 12
Pages: 1612-29
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25440058 | J:218789
First Author: Gordts PL
Year: 2014
Journal: Cell Metab
Title: Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling.
Volume: 20
Issue: 5
Pages: 813-26
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Publication
20041412 | J:174474
First Author: Wang H
Year: 2010
Journal: Hepatology
Title: Interplay of hepatic and myeloid signal transducer and activator of transcription 3 in facilitating liver regeneration via tempering innate immunity.
Volume: 51
Issue: 4
Pages: 1354-62
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Publication
38489266 | J:348601
First Author: Pitter MR
Year: 2024
Journal: Cell Rep
Title: PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages.
Volume: 43
Issue: 3
Pages: 113942
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Publication
35081346 | J:332371
First Author: Yang L
Year: 2022
Journal: Cell Rep
Title: Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription.
Volume: 38
Issue: 4
Pages: 110302
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Publication
31720043 | J:283295
First Author: Kim D
Year: 2019
Journal: Immune Netw
Title: Ubiquitin E3 Ligase Pellino-1 Inhibits IL-10-mediated M2c Polarization of Macrophages, Thereby Suppressing Tumor Growth.
Volume: 19
Issue: 5
Pages: e32
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31732720 | J:290132
First Author: Austin RJ
Year: 2020
Journal: Leukemia
Title: Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations.
Volume: 34
Issue: 4
Pages: 1075-1089
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28408410 | J:242006
First Author: Fujita Y
Year: 2017
Journal: J Exp Med
Title: Decreased cohesin in the brain leads to defective synapse development and anxiety-related behavior.
Volume: 214
Issue: 5
Pages: 1431-1452
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Publication
31532798 | J:279962
First Author: Yue L
Year: 2019
Journal: PLoS One
Title: PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils.
Volume: 14
Issue: 9
Pages: e0222753
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19474293 | J:150081
First Author: Heinonen KM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-gamma signaling.
Volume: 106
Issue: 23
Pages: 9368-72
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Publication
35981499 | J:346640
First Author: Wang J
Year: 2022
Journal: Blood
Title: Leukemia inhibitory factor protects against graft-versus-host disease while preserving graft-versus-leukemia activity.
Volume: 140
Issue: 19
Pages: 2076-2090
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Publication
23021953 | J:188562
First Author: Li S
Year: 2012
Journal: Immunity
Title: The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells.
Volume: 37
Issue: 4
Pages: 685-96
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8700208 | J:34060
First Author: Thierfelder WE
Year: 1996
Journal: Nature
Title: Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells.
Volume: 382
Issue: 6587
Pages: 171-4
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22252317 | J:183707
First Author: Farlik M
Year: 2012
Journal: Mol Cell Biol
Title: Contribution of a TANK-binding kinase 1-interferon (IFN) regulatory factor 7 pathway to IFN-γ-induced gene expression.
Volume: 32
Issue: 6
Pages: 1032-43
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Publication
27966526 | J:243233
 
First Author: Huang B
Year: 2016
Journal: Nat Commun
Title: Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone.
Volume: 7
Pages: 13885
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Publication
35963236 | J:328359
First Author: Ryu S
Year: 2022
Journal: Immunity
Title: The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging.
Volume: 55
Issue: 9
Pages: 1609-1626.e7
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Publication
18390731 | J:134253
First Author: Zhao W
Year: 2008
Journal: J Immunol
Title: A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs.
Volume: 180
Issue: 8
Pages: 5483-9
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11278899 | J:69604
First Author: Tibbles HE
Year: 2001
Journal: J Biol Chem
Title: Role of a JAK3-dependent biochemical signaling pathway in platelet activation and aggregation.
Volume: 276
Issue: 21
Pages: 17815-22
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Publication
32503978 | J:291910
First Author: Swaminathan S
Year: 2020
Journal: Nat Commun
Title: MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies.
Volume: 11
Issue: 1
Pages: 2860
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Publication
15311277 | J:92167
First Author: Liu B
Year: 2004
Journal: Nat Immunol
Title: PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity.
Volume: 5
Issue: 9
Pages: 891-8
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Publication
23603793 | J:197354
First Author: Gracias DT
Year: 2013
Journal: Nat Immunol
Title: The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling.
Volume: 14
Issue: 6
Pages: 593-602
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Publication
37002214 | J:335316
First Author: Benvie AM
Year: 2023
Journal: Nat Commun
Title: Age-dependent Pdgfrβ signaling drives adipocyte progenitor dysfunction to alter the beige adipogenic niche in male mice.
Volume: 14
Issue: 1
Pages: 1806
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Publication
35093191 | J:328582
First Author: Meijer M
Year: 2022
Journal: Neuron
Title: Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility.
Volume: 110
Issue: 7
Pages: 1193-1210.e13
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Publication
31495563 | J:281559
First Author: Steinparzer I
Year: 2019
Journal: Mol Cell
Title: Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions.
Volume: 76
Issue: 3
Pages: 485-499.e8
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Publication
20226532 | J:160639
First Author: Dimitrova P
Year: 2010
Journal: Mol Immunol
Title: The role of properdin in murine zymosan-induced arthritis.
Volume: 47
Issue: 7-8
Pages: 1458-66
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Publication
30687322 | J:294746
 
First Author: Piedra-Quintero ZL
Year: 2018
Journal: Front Immunol
Title: Myosin 1F Regulates M1-Polarization by Stimulating Intercellular Adhesion in Macrophages.
Volume: 9
Pages: 3118
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Publication
35882956 | J:342306
First Author: Rios FJ
Year: 2022
Journal: Commun Biol
Title: TRPM7 deficiency exacerbates cardiovascular and renal damage induced by aldosterone-salt.
Volume: 5
Issue: 1
Pages: 746
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Publication
33400688 | J:347955
 
First Author: Kawashima K
Year: 2021
Journal: JCI Insight
Title: Restoration of type I interferon signaling in intrahepatically primed CD8+ T cells promotes functional differentiation.
Volume: 6
Issue: 3
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•
Publication
- | J:321879
     
First Author: Liu Y
Year: 2022
Journal: bioRxiv
Title: A live-attenuated sarS-CoV-2 vaccine candidate with accessory protein deletions.
•
•
•
•
•
Publication
36918560 | J:339798
First Author: Du J
Year: 2023
Journal: Nat Commun
Title: BRD9-mediated chromatin remodeling suppresses osteoclastogenesis through negative feedback mechanism.
Volume: 14
Issue: 1
Pages: 1413
•
•
•
•
•
Publication
37688915 | J:340827
First Author: Ge H
Year: 2023
Journal: Int Immunopharmacol
Title: Stress aggravates imiquimod-induced psoriasiform inflammation by promoting M1 macrophage polarization.
Volume: 124
Issue: Pt A
Pages: 110899
•
•
•
•
•
Publication
32286295 | J:287143
First Author: Ma J
Year: 2020
Journal: Nat Commun
Title: Glycogen metabolism regulates macrophage-mediated acute inflammatory responses.
Volume: 11
Issue: 1
Pages: 1769
•
•
•
•
•
Publication
35476975 | J:325263
First Author: Jhala G
Year: 2022
Journal: Cell Rep
Title: Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse.
Volume: 39
Issue: 4
Pages: 110747
•
•
•
•
•
Publication
10675904 | J:60416
First Author: Chatterjee-Kishore M
Year: 2000
Journal: Trends Cell Biol
Title: Association of STATs with relatives and friends.
Volume: 10
Issue: 3
Pages: 106-11
•
•
•
•
•
Publication
8990168 | J:37540
First Author: Weihua X
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Interferon gamma-induced transcription of the murine ISGF3gamma (p48) gene is mediated by novel factors.
Volume: 94
Issue: 1
Pages: 103-8
•
•
•
•
•
Publication
10210773 | J:55985
First Author: Demoulin JB
Year: 1999
Journal: Eur Cytokine Netw
Title: Ly-6A/E induction by interleukin-6 and interleukin-9 in T cells.
Volume: 10
Issue: 1
Pages: 49-56
•
•
•
•
•
Publication
15148408 | J:90656
First Author: Sizemore N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Inhibitor of kappaB kinase is required to activate a subset of interferon gamma-stimulated genes.
Volume: 101
Issue: 21
Pages: 7994-8
•
•
•
•
•
Publication
16365452 | J:126611
First Author: Han SH
Year: 2006
Journal: J Immunol
Title: Lipoteichoic acid-induced nitric oxide production depends on the activation of platelet-activating factor receptor and Jak2.
Volume: 176
Issue: 1
Pages: 573-9
•
•
•
•
•
Publication
19124715 | J:143503
First Author: Quirion MR
Year: 2009
Journal: J Immunol
Title: Cutting edge: Ikaros is a regulator of Th2 cell differentiation.
Volume: 182
Issue: 2
Pages: 741-5
•
•
•
•
•
Publication
18950753 | J:145046
First Author: Yamana J
Year: 2009
Journal: Cell Immunol
Title: Enhanced induction of LPS-induced fibroblast MCP-1 by interferon-gamma: involvement of JNK and MAPK phosphatase-1.
Volume: 255
Issue: 1-2
Pages: 26-32
•
•
•
•
•
Publication
19361784 | J:149493
First Author: Hirata N
Year: 2009
Journal: Cell Immunol
Title: Selective regulation of interleukin-10 production via Janus kinase pathway in murine conventional dendritic cells.
Volume: 258
Issue: 1
Pages: 9-17
•
•
•
•
•
Publication
26553978 | J:228067
First Author: Mertens C
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Mutations in the linker domain affect phospho-STAT3 function and suggest targets for interrupting STAT3 activity.
Volume: 112
Issue: 48
Pages: 14811-6
•
•
•
•
•
Publication
29618525 | J:261485
First Author: Nabekura T
Year: 2018
Journal: J Immunol
Title: Crk Adaptor Proteins Regulate NK Cell Expansion and Differentiation during Mouse Cytomegalovirus Infection.
Volume: 200
Issue: 10
Pages: 3420-3428
•
•
•
•
•
Publication
32358509 | J:292350
First Author: Liu XD
Year: 2020
Journal: Nat Commun
Title: PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma.
Volume: 11
Issue: 1
Pages: 2135
•
•
•
•
•
Publication
31924749 | J:297868
First Author: Li P
Year: 2020
Journal: Cell Death Dis
Title: Loss of PARP-1 attenuates diabetic arteriosclerotic calcification via Stat1/Runx2 axis.
Volume: 11
Issue: 1
Pages: 22
•
•
•
•
•
Publication
32803171 | J:304434
First Author: Thibaut R
Year: 2020
Journal: Nat Cancer
Title: Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment.
Volume: 1
Issue: 3
Pages: 302-314
•
•
•
•
•
Publication
33852830 | J:305806
First Author: Saxton RA
Year: 2021
Journal: Immunity
Title: The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design.
Volume: 54
Issue: 4
Pages: 660-672.e9
•
•
•
•
•
Publication
34878838 | J:320018
First Author: Wu Y
Year: 2021
Journal: Sci Adv
Title: TREM-2 is a sensor and activator of T cell response in SARS-CoV-2 infection.
Volume: 7
Issue: 50
Pages: eabi6802
•
•
•
•
•
Publication
28405614 | J:319264
First Author: Yuan Y
Year: 2017
Journal: JCI Insight
Title: IL-21 is required for CD4 memory formation in response to viral infection.
Volume: 2
Issue: 7
Pages: e90652
•
•
•
•
•




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