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Search results 1201 to 1300 out of 2796 for Thy1

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Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Tg(Thy1-APPSw)10Jiri/? Tg(Thy1-PSEN1*M146V)#Jiri/?
Background: B6.Cg-Tg(Thy1-APPSw)10Jiri Tg(Thy1-PSEN1*M146V)#Jiri
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-DCTN1*G59S)M2Pcw/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-MAPT*L266V*G272V)13Ema/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-SNCA*E57K)16Ema/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dctn1/Dctn1 Tg(Thy1-cre)1Vln/?
Background: involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-DCTN1*G71A)#Ytsu/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APP)3Somm/?
Background: involves: C57BL/6 * C57BL/6J * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lamp5/Lamp5<+> Tg(Thy1-APP)3Somm/?
Background: involves: C57BL/6 * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lamp5/Lamp5 Tg(Thy1-APP)3Somm/?
Background: involves: C57BL/6 * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(Thy1-cre)1Vln/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bace1/Bace1 Tg(Thy1-cre)1Vln/?
Background: B6.Cg-Bace1 Tg(Thy1-cre)1Vln
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-GFP*)1Hadj/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Publication
21272100 | J:174647
First Author: Prasad K
Year: 2011
Journal: Eur J Neurosci
Title: Biochemical and morphological consequences of human α-synuclein expression in a mouse α-synuclein null background.
Volume: 33
Issue: 4
Pages: 642-56
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Publication
12009758 | J:76482
First Author: Richfield EK
Year: 2002
Journal: Exp Neurol
Title: Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice.
Volume: 175
Issue: 1
Pages: 35-48
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Publication
16713278 | J:111193
First Author: Chen L
Year: 2006
Journal: Neurobiol Dis
Title: Proteasome dysfunction in aged human alpha-synuclein transgenic mice.
Volume: 23
Issue: 1
Pages: 120-6
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Publication
21333719 | J:173693
 
First Author: Peneder TM
Year: 2011
Journal: Neuroscience
Title: Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice.
Volume: 180
Pages: 280-92
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Publication
15009131 | J:96494
First Author: Thiruchelvam MJ
Year: 2004
Journal: Eur J Neurosci
Title: Risk factors for dopaminergic neuron loss in human alpha-synuclein transgenic mice.
Volume: 19
Issue: 4
Pages: 845-54
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Strain
MGI:3784588 | C57BL/6J-Tg(Th-SNCA*A30P*A53T)39Eric/J
Attribute String: transgenic, coisogenic
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Publication
38351057 | J:352009
 
First Author: Keomanivong C
Year: 2024
Journal: eNeuro
Title: Mice Expressing A53T/A30P Mutant Alpha-Synuclein in Dopamine Neurons Do Not Display Behavioral Deficits.
Volume: 11
Issue: 2
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Publication
33805843 | J:310935
 
First Author: Pavia-Collado R
Year: 2021
Journal: Int J Mol Sci
Title: Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
Volume: 22
Issue: 6
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Publication
29571747 | J:266606
First Author: Zhang Q
Year: 2018
Journal: Biochim Biophys Acta Gen Subj
Title: Cdk5 suppression blocks SIRT1 degradation via the ubiquitin-proteasome pathway in Parkinson's disease models.
Volume: 1862
Issue: 6
Pages: 1443-1451
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Publication
31758049 | J:287103
First Author: Kilpeläinen T
Year: 2019
Journal: Sci Rep
Title: Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease.
Volume: 9
Issue: 1
Pages: 17382
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Publication
36351818 | J:332059
 
First Author: Paul S
Year: 2022
Journal: eNeuro
Title: Cyclin-Dependent Kinase 5 Regulates cPLA2 Activity and Neuroinflammation in Parkinson's Disease.
Volume: 9
Issue: 6
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Publication
28476570 | J:249386
 
First Author: Jiao F
Year: 2017
Journal: Behav Brain Res
Title: Expression signatures of long non-coding RNA in the substantia nigra of pre-symptomatic mouse model of Parkinson's disease.
Volume: 331
Pages: 123-130
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Publication
36497031 | J:346174
 
First Author: Tiwari S
Year: 2022
Journal: Cells
Title: UBA52 Is Crucial in HSP90 Ubiquitylation and Neurodegenerative Signaling during Early Phase of Parkinson's Disease.
Volume: 11
Issue: 23
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Publication
28771510 | J:248076
First Author: Yan J
Year: 2017
Journal: PLoS One
Title: Quantitative proteomics in A30P*A53T α-synuclein transgenic mice reveals upregulation of Sel1l.
Volume: 12
Issue: 8
Pages: e0182092
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Publication
26317511 | J:243019
First Author: Su X
Year: 2015
Journal: PLoS One
Title: PGC-1α Promoter Methylation in Parkinson's Disease.
Volume: 10
Issue: 8
Pages: e0134087
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Publication
37981650 | J:354471
First Author: McFleder RL
Year: 2023
Journal: Nat Commun
Title: Brain-to-gut trafficking of alpha-synuclein by CD11c(+) cells in a mouse model of Parkinson's disease.
Volume: 14
Issue: 1
Pages: 7529
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Allele
Thy1<a> | MGI:3579311
   
Name: thymus cell antigen 1, theta; a variant
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Allele
Thy1<b> | MGI:3717471
   
Name: thymus cell antigen 1, theta; b variant
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Genotype
Genotype
Symbol: Tg(Th-SNCA*A30P*A53T)39Eric/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Th-SNCA*A30P*A53T)39Eric/?
Background: involves: C57BL/6 * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Publication
26223192 | J:253752
 
First Author: Almeida FF
Year: 2015
Journal: Sci Rep
Title: Identification of a novel lymphoid population in the murine epidermis.
Volume: 5
Pages: 12554
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Publication
17273993 | J:117902
First Author: Hager-Theodorides AL
Year: 2007
Journal: Eur J Immunol
Title: Beta-selection: abundance of TCRbeta-/gammadelta- CD44- CD25- (DN4) cells in the foetal thymus.
Volume: 37
Issue: 2
Pages: 487-500
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Publication
16027115 | J:102154
First Author: Rockenstein E
Year: 2005
Journal: J Biol Chem
Title: High beta-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease.
Volume: 280
Issue: 38
Pages: 32957-67
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Publication
16818745 | J:125056
First Author: Clements JL
Year: 2006
Journal: J Immunol
Title: Impaired generation of CD8+ thymocytes in Ets-1-deficient mice.
Volume: 177
Issue: 2
Pages: 905-12
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Publication
27114530 | J:232197
First Author: Nagy M
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Extended survival of misfolded G85R SOD1-linked ALS mice by transgenic expression of chaperone Hsp110.
Volume: 113
Issue: 19
Pages: 5424-8
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Publication
16566922 | J:111367
First Author: Wootz H
Year: 2006
Journal: Exp Cell Res
Title: XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice.
Volume: 312
Issue: 10
Pages: 1890-8
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Publication
28348271 | J:247739
First Author: Mokada-Gopal L
Year: 2017
Journal: J Immunol
Title: Identification of Novel STAT6-Regulated Proteins in Mouse B Cells by Comparative Transcriptome and Proteome Analysis.
Volume: 198
Issue: 9
Pages: 3737-3745
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Publication
16487970 | J:107899
First Author: Eckenstein FP
Year: 2006
Journal: Exp Neurol
Title: Neuronal vulnerability in transgenic mice expressing an inducible dominant-negative FGF receptor.
Volume: 198
Issue: 2
Pages: 338-49
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Publication
21469122 | J:175405
First Author: Ishifune C
Year: 2011
Journal: Eur J Immunol
Title: Notch signaling regulates the development of a novel type of Thy1-expressing dendritic cell in the thymus.
Volume: 41
Issue: 5
Pages: 1309-20
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Publication
21148560 | J:169481
First Author: Jawhar S
Year: 2011
Journal: J Biol Chem
Title: Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice.
Volume: 286
Issue: 6
Pages: 4454-60
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Publication
23858471 | J:198773
First Author: Chan CK
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells.
Volume: 110
Issue: 31
Pages: 12643-8
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Publication
16906128 | J:116895
First Author: Radde R
Year: 2006
Journal: EMBO Rep
Title: Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology.
Volume: 7
Issue: 9
Pages: 940-6
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Publication
19701892 | J:152149
First Author: Miazek A
Year: 2009
Journal: Eur J Immunol
Title: Peripheral Thy1+ lymphocytes rearranging TCR-gammadelta genes in LAT-deficient mice.
Volume: 39
Issue: 9
Pages: 2596-605
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Publication
23734096 | J:209636
 
First Author: Batti L
Year: 2013
Journal: Front Mol Neurosci
Title: Transgenic mouse lines for non-invasive ratiometric monitoring of intracellular chloride.
Volume: 6
Pages: 11
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Publication
11113617 | J:66439
First Author: Sommer B
Year: 2000
Journal: Exp Gerontol
Title: Mouse models of alpha-synucleinopathy and Lewy pathology.
Volume: 35
Issue: 9-10
Pages: 1389-403
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Publication
7575994 | J:26213
First Author: Fabien N
Year: 1995
Journal: J Autoimmun
Title: Pancreatic lymph nodes are early targets of T cells during adoptive transfer of diabetes in NOD mice.
Volume: 8
Issue: 3
Pages: 323-34
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Publication
18028883 | J:130207
 
First Author: Kilic E
Year: 2007
Journal: Brain Res
Title: Poxvirus-derived cytokine response modifier A (CrmA) does not protect against focal cerebral ischemia in mice.
Volume: 1185
Pages: 293-300
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Publication
18702696 | J:140576
First Author: Fleming SM
Year: 2008
Journal: Eur J Neurosci
Title: Olfactory deficits in mice overexpressing human wildtype alpha-synuclein.
Volume: 28
Issue: 2
Pages: 247-56
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Publication
21193046 | J:171294
First Author: Fleming SM
Year: 2011
Journal: Mol Cell Neurosci
Title: A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions.
Volume: 46
Issue: 3
Pages: 597-606
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Publication
21896768 | J:176579
First Author: Choi KY
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Expression of the metabotropic glutamate receptor 5 (mGluR5) induces melanoma in transgenic mice.
Volume: 108
Issue: 37
Pages: 15219-24
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Publication
23576551 | J:198348
First Author: Burgos-Ojeda D
Year: 2013
Journal: Cancer Res
Title: A novel model for evaluating therapies targeting human tumor vasculature and human cancer stem-like cells.
Volume: 73
Issue: 12
Pages: 3555-65
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Publication
24440055 | J:212059
 
First Author: Chabrier MA
Year: 2014
Journal: Neurobiol Dis
Title: Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease.
Volume: 64
Pages: 107-17
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Publication
31302264 | J:293182
 
First Author: Diuba AV
Year: 2020
Journal: Neuroscience
Title: CLARITY analysis of the Cl/pH sensor expression in the brain of transgenic mice.
Volume: 439
Pages: 181-194
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Publication
32745471 | J:301248
 
First Author: Holman SP
Year: 2020
Journal: Exp Neurol
Title: Neuronal mitochondrial calcium uniporter deficiency exacerbates axonal injury and suppresses remyelination in mice subjected to experimental autoimmune encephalomyelitis.
Volume: 333
Pages: 113430
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Publication
22779732 | J:318096
First Author: Wang L
Year: 2012
Journal: Neurogastroenterol Motil
Title: Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation.
Volume: 24
Issue: 9
Pages: e425-36
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Publication
37798679 | J:342503
First Author: Schweighauser M
Year: 2023
Journal: Acta Neuropathol Commun
Title: Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.
Volume: 11
Issue: 1
Pages: 160
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Publication
21885656 | J:178376
First Author: Bütikofer L
Year: 2011
Journal: FASEB J
Title: Destabilization of the neuromuscular junction by proteolytic cleavage of agrin results in precocious sarcopenia.
Volume: 25
Issue: 12
Pages: 4378-93
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Publication
22187053 | J:181971
First Author: Sharma M
Year: 2012
Journal: EMBO J
Title: CSPα knockout causes neurodegeneration by impairing SNAP-25 function.
Volume: 31
Issue: 4
Pages: 829-41
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Publication
20133599 | J:157578
First Author: Fukata Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy.
Volume: 107
Issue: 8
Pages: 3799-804
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Publication
24064336 | J:205004
First Author: Casadei N
Year: 2014
Journal: Hum Mol Genet
Title: Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice.
Volume: 23
Issue: 3
Pages: 767-81
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Publication
18272491 | J:132182
First Author: Buxbaum JN
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity.
Volume: 105
Issue: 7
Pages: 2681-6
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Publication
24849358 | J:211347
First Author: Wang X
Year: 2014
Journal: J Neurosci
Title: The systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice.
Volume: 34
Issue: 21
Pages: 7253-65
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Publication
21880910 | J:176224
First Author: Li X
Year: 2011
Journal: J Neurosci
Title: Neuronal production of transthyretin in human and murine Alzheimer's disease: is it protective?
Volume: 31
Issue: 35
Pages: 12483-90
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Publication
28864542 | J:249242
First Author: Li C
Year: 2017
Journal: EMBO J
Title: Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn-mediated local protein translation.
Volume: 36
Issue: 21
Pages: 3120-3138
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Publication
21623957 | J:176369
First Author: English AW
Year: 2011
Journal: Eur J Neurosci
Title: Neurotrophin-4/5 is implicated in the enhancement of axon regeneration produced by treadmill training following peripheral nerve injury.
Volume: 33
Issue: 12
Pages: 2265-71
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Publication
17724122 | J:134832
First Author: He P
Year: 2007
Journal: J Cell Biol
Title: Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice.
Volume: 178
Issue: 5
Pages: 829-41
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Publication
28945221 | J:258023
First Author: Ferreira DG
Year: 2017
Journal: Nat Neurosci
Title: α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B.
Volume: 20
Issue: 11
Pages: 1569-1579
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Publication
28298456 | J:241870
First Author: Czirr E
Year: 2017
Journal: J Exp Med
Title: Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.
Volume: 214
Issue: 4
Pages: 1081-1092
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Publication
10828523 | J:118051
First Author: Bronfman FC
Year: 2000
Journal: Neuroscience
Title: No evidence for cholinergic problems in apolipoprotein E knockout and apolipoprotein E4 transgenic mice.
Volume: 97
Issue: 3
Pages: 411-8
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Publication
10702411 | J:128837
First Author: Tesseur I
Year: 2000
Journal: Am J Pathol
Title: Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice.
Volume: 156
Issue: 3
Pages: 951-64
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Publication
27221710 | J:258640
First Author: Donner L
Year: 2016
Journal: Sci Signal
Title: Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3-induced outside-in signaling and clusterin release.
Volume: 9
Issue: 429
Pages: ra52
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Strain
MGI:5554549 | C3A.Cg-Pde6b<+> Tg(Thy1-CFP)23Jrs/SjJ
Attribute String: transgenic, mutant strain, congenic, wild-type allele
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Publication
34515347 | J:312459
First Author: Doron-Mandel E
Year: 2021
Journal: EMBO J
Title: The glycine arginine-rich domain of the RNA-binding protein nucleolin regulates its subcellular localization.
Volume: 40
Issue: 20
Pages: e107158
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Strain
MGI:5554559 | D2.Cg-Gpnmb<+> Tg(Thy1-YFP)HJrs/SjJ
Attribute String: congenic, mutant strain, transgenic, wild-type allele
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Strain
MGI:5554550 | D2.Cg-Gpnmb<+> Tg(Thy1-CFP)23Jrs/SjJ
Attribute String: congenic, mutant strain, transgenic, wild-type allele
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Publication
22426214 | J:184547
First Author: Howell GR
Year: 2012
Journal: J Clin Invest
Title: Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma.
Volume: 122
Issue: 4
Pages: 1246-61
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Publication
10964942 | J:64205
First Author: Kahle PJ
Year: 2000
Journal: J Neurosci
Title: Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain.
Volume: 20
Issue: 17
Pages: 6365-73
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Publication
23363402 | J:199504
First Author: Fagerqvist T
Year: 2013
Journal: J Neurochem
Title: Monoclonal antibodies selective for α-synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and α-synuclein transgenic mice with the disease-causing A30P mutation.
Volume: 126
Issue: 1
Pages: 131-44
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Publication
33041770 | J:308537
 
First Author: Stylianou M
Year: 2020
Journal: Front Neurosci
Title: Early Disruption of Cortical Sleep-Related Oscillations in a Mouse Model of Dementia With Lewy Bodies (DLB) Expressing Human Mutant (A30P) Alpha-Synuclein.
Volume: 14
Pages: 579867
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Publication
29524634 | J:262431
 
First Author: Robson E
Year: 2018
Journal: Neuroscience
Title: Impaired Fast Network Oscillations and Mitochondrial Dysfunction in a Mouse Model of Alpha-synucleinopathy (A30P).
Volume: 377
Pages: 161-173
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Publication
29623065 | J:337639
 
First Author: Almandoz-Gil L
Year: 2018
Journal: Front Neurol
Title: In Situ Proximity Ligation Assay Reveals Co-Localization of Alpha-Synuclein and SNARE Proteins in Murine Primary Neurons.
Volume: 9
Pages: 180
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Publication
24851801 | J:214308
 
First Author: Lindström V
Year: 2014
Journal: Neurobiol Dis
Title: Immunotherapy targeting α-synuclein protofibrils reduced pathology in (Thy-1)-h[A30P] α-synuclein mice.
Volume: 69
Pages: 134-43
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Publication
31422098 | J:282744
 
First Author: Keane PC
Year: 2019
Journal: Neurosci Lett
Title: Trichloroethylene and its metabolite TaClo lead to degeneration of substantia nigra dopaminergic neurones: Effects in wild type and human A30P mutant α-synuclein mice.
Volume: 711
Pages: 134437
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Publication
23209687 | J:195450
First Author: Schell H
Year: 2012
Journal: PLoS One
Title: Impaired c-Fos and polo-like kinase 2 induction in the limbic system of fear-conditioned α-synuclein transgenic mice.
Volume: 7
Issue: 11
Pages: e50245
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Publication
22579457 | J:194440
First Author: Szegő ÉM
Year: 2013
Journal: Neurobiol Aging
Title: Impairment of the septal cholinergic neurons in MPTP-treated A30P α-synuclein mice.
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Title: Visualization of early oligomeric α-synuclein pathology and its impact on the dopaminergic system in the (Thy-1)-h[A30P]α-syn transgenic mouse model.
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Title: Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage.
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Title: A β-Wrapin Targeting the N-Terminus of α-Synuclein Monomers Reduces Fibril-Induced Aggregation in Neurons.
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Title: Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson's Disease.
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