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Nat Neurosci |
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Breunig JJ |
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Proc Natl Acad Sci U S A |
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Passemard S |
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J Clin Invest |
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Pavlinkova G |
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BMC Genomics |
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Nat Neurosci |
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Elife |
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Mol Cell |
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Genes Dev |
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Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. |
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Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells. |
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| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
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| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
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| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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| GXD Expression |
| Probe: |
MGI:7428885 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-01-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754423 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:7428941 |
| Age: |
embryonic day 15.0-16.0 |
| Image: |
1E3 |
| Note: |
Expression co-localized with Dcx in immature neurons. |
| Specimen Label: |
1E3 |
| Detected: |
true |
| Specimen Num: |
11 |
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| GXD Expression |
| Probe: |
MGI:4461295 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-02-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3540728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6389049 |
| Age: |
postnatal adult |
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| Note: |
Coexpressed with Dcx in the subgranular zone. |
| Specimen Label: |
4M |
| Detected: |
true |
| Specimen Num: |
12 |
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| GO Term |
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| Publication |
| First Author: |
Yoshihara S |
| Year: |
2014 |
| Journal: |
Cell Rep |
| Title: |
Npas4 regulates Mdm2 and thus Dcx in experience-dependent dendritic spine development of newborn olfactory bulb interneurons. |
| Volume: |
8 |
| Issue: |
3 |
| Pages: |
843-57 |
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| DO Term |
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| GXD Expression |
| Probe: |
MGI:5311560 |
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2023-05-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:7468644 |
| Age: |
embryonic day 18.5 |
| Image: |
S3D |
| Note: |
The vast majority of expressing cells also express Dcx as quantified in Table S2. |
| Specimen Label: |
S3D |
| Detected: |
true |
| Specimen Num: |
8 |
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| GXD Expression |
| Probe: |
MGI:4461295 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-02-07 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6389049 |
| Age: |
postnatal adult |
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| Note: |
Coexpressed with Dcx in type A cells (migrating neuroblasts), but not in condensed chromosomes. |
| Specimen Label: |
4H/J |
| Detected: |
true |
| Specimen Num: |
11 |
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| GXD Expression |
| Probe: |
MGI:6436314 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-06-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3583128 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6436562 |
| Age: |
postnatal adult |
| Image: |
2I |
| Note: |
Expression not co-localizing with Dcx within any cells of dentate gyrus. |
| Specimen Label: |
2I |
| Detected: |
true |
| Specimen Num: |
15 |
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| GXD Expression |
| Probe: |
MGI:6436314 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-06-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3583128 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6436562 |
| Age: |
postnatal adult |
| Image: |
2J |
| Note: |
Expression not co-localizing with Dcx within any cells of dentate gyrus. |
| Specimen Label: |
2J |
| Detected: |
true |
| Specimen Num: |
16 |
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| GXD Expression |
| Probe: |
MGI:6436314 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-06-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3671628 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6436562 |
| Age: |
postnatal adult |
| Image: |
3E |
| Note: |
Expression not co-localizing with Dcx in any cells of lateral ventricles. |
| Specimen Label: |
3E |
| Detected: |
true |
| Specimen Num: |
19 |
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| GXD Expression |
| Probe: |
MGI:5521550 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-12-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1609218 |
| Pattern: |
Regionally restricted |
| Stage: |
TS18 |
| Assay Id: |
MGI:6267023 |
| Age: |
embryonic day 11.0 |
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| Note: |
Expression was detected at upper and lower border regions. Immunopositive long radial glia-like fibers extended radially amid extensive (non-overlapping) Dcx expression. |
| Specimen Label: |
6L |
| Detected: |
true |
| Specimen Num: |
6 |
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| GXD Expression |
| Probe: |
MGI:6690455 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-04-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271121 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:6690500 |
| Age: |
embryonic day 13.5 |
| Image: |
8B |
| Note: |
There were a few cells co-expressed with Dcx in the basal cortical plate. Mostly not co-expressed with Dcx. |
| Specimen Label: |
8B |
| Detected: |
true |
| Specimen Num: |
12 |
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| GXD Expression |
| Probe: |
MGI:6515614 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-04-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640617 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:6515621 |
| Age: |
embryonic day 10.5 |
| Image: |
2d' |
| Note: |
Expression in majority of limb bud mesenchymal cells. Expression co-localized with Dcx particularly in middle core region of limb bud. |
| Specimen Label: |
2d' |
| Detected: |
true |
| Specimen Num: |
1 |
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| GXD Expression |
| Probe: |
MGI:4461295 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-02-07 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6389049 |
| Age: |
postnatal adult |
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| Note: |
Coexpressed with Dcx in type A cells (migrating neuroblasts). Expressed in the nuclei, and Dcx in their cell bodies. |
| Specimen Label: |
4F |
| Detected: |
true |
| Specimen Num: |
10 |
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| Allele |
| Name: |
doublecortin; endonuclease-mediated mutation 1, Itaru Imayoshi |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Recombinase |
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| Allele |
| Name: |
doublecortin; endonuclease-mediated mutation 2, Itaru Imayoshi |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Recombinase |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
573
 |
| Fragment?: |
true |
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•
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
573
 |
| Fragment?: |
true |
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•
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
373
 |
| Fragment?: |
true |
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| Publication |
| First Author: |
Choi SH |
| Year: |
2010 |
| Journal: |
Genes Dev |
| Title: |
Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells. |
| Volume: |
24 |
| Issue: |
12 |
| Pages: |
1236-41 |
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| Protein Domain |
| Type: |
Family |
| Description: |
TRPC4AP is a substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control []. |
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| Allele |
| Name: |
transgene insertion 1, Markus Schwaninger |
| Allele Type: |
Transgenic |
| Attribute String: |
Inducible, Recombinase |
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| Publication |
| First Author: |
Bergoglio E |
| Year: |
2021 |
| Journal: |
Neurosci Res |
| Title: |
Spatial and temporal diversity of DCLK1 isoforms in developing mouse brain. |
| Volume: |
170 |
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| Pages: |
154-165 |
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