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Search results 1301 to 1400 out of 1417 for Egr2

0.032s
Type Details Score
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 470  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 36  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 72  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: true
Publication
First Author: Noritsugu K
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Identification of zinc finger transcription factor EGR2 as a novel acetylated protein.
Volume: 489
Issue: 4
Pages: 455-459
Publication
First Author: Wang J
Year: 2020
Journal: Nat Commun
Title: CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair.
Volume: 11
Issue: 1
Pages: 4133
Pathway
Publication
First Author: Kamran M
Year: 2020
Journal: J Immunol
Title: The Clusters of Transcription Factors NFATC2, STAT5, GATA2, AP1, RUNX1 and EGR2 Binding Sites at the Induced Il13 Enhancers Mediate Il13 Gene Transcription in Response to Antigenic Stimulation.
Volume: 205
Issue: 12
Pages: 3311-3318
Interaction Experiment
Description: The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitination.
GXD Expression
Probe: MGI:1349610
Assay Type: RNA in situ
Annotation Date: 1999-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1629714
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:1350575
Age: embryonic day 9.0
Image: 1M
Note: The expression is contained entirely within the Egr2 expression domain.
Specimen Label: 1M
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:1349612
Assay Type: RNA in situ
Annotation Date: 1999-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1629713
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:1350576
Age: embryonic day 8.5
Image: 1T
Note: Nab2 expression is contained within the Egr2 expression domain.
Specimen Label: 1T
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:1349610
Assay Type: RNA in situ
Annotation Date: 1999-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1630514
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:1350575
Age: embryonic day 9.0
Image: 1M
Note: The expression is contained entirely within the Egr2 expression domain.
Specimen Label: 1M
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:1349612
Assay Type: RNA in situ
Annotation Date: 1999-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1630513
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:1350576
Age: embryonic day 8.5
Image: 1T
Note: Nab2 expression is contained within the Egr2 expression domain.
Specimen Label: 1T
Detected: true
Specimen Num: 7
Allele
Name: transgene insertion 1, Patrick Charnay
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: early growth response 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 1165  
Fragment?: false
Publication
First Author: Chavrier P
Year: 1990
Journal: EMBO J
Title: The segment-specific gene Krox-20 encodes a transcription factor with binding sites in the promoter region of the Hox-1.4 gene.
Volume: 9
Issue: 4
Pages: 1209-18
Publication
First Author: Gilardi P
Year: 1991
Journal: Biochimie
Title: Krox-20: a candidate gene for the regulation of pattern formation in the hindbrain.
Volume: 73
Issue: 1
Pages: 85-91
Publication
First Author: Vesque C
Year: 1992
Journal: Nucleic Acids Res
Title: Mapping functional regions of the segment-specific transcription factor Krox-20.
Volume: 20
Issue: 10
Pages: 2485-92
GXD Expression
Probe: MGI:1336943
Assay Type: RNA in situ
Annotation Date: 1999-06-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1629713
Pattern: Uniform
Stage: TS13
Assay Id: MGI:1338214
Age: embryonic day 8.5
Image: 6. H
Note: Specimen was double hydridized with Egr2 and Epha7 probes and expression was inferred from previous specimens.
Specimen Label: 6. H
Detected: true
Specimen Num: 12
GXD Expression
Probe: MGI:1336943
Assay Type: RNA in situ
Annotation Date: 1999-06-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1630513
Pattern: Uniform
Stage: TS13
Assay Id: MGI:1338214
Age: embryonic day 8.5
Image: 6. H
Note: Specimen was double hydridized with Egr2 and Epha7 probes and expression was inferred from previous specimens.
Specimen Label: 6. H
Detected: true
Specimen Num: 12
Strain
Attribute String: mutant stock, targeted mutation, transgenic
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Allele
Name: early growth response 2; targeted mutation 1, Jeffrey Milbrandt
Allele Type: Targeted
Attribute String: Hypomorph
Allele
Name: early growth response 2; targeted mutation 2, Jeffrey Milbrandt
Allele Type: Targeted
Attribute String: Humanized sequence
GXD Expression
Probe: MGI:5436064
Assay Type: RNA in situ
Annotation Date: 2012-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614812
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:5436256
Age: embryonic day 8.0
Image: 1B
Note: Expression was up-regulated in the anterior part. The expression domain coincided with the narrow band of cells initially activating Egr2 (Krox-20 - Xgal staining).
Specimen Label: 1B
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:1202170
Assay Type: RNA in situ
Annotation Date: 2012-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3282012
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:5436418
Age: embryonic day 8.0
Image: 4F
Note: Expression was detected in a continuous rhombomere 2,3,4 domain extending caudally to the rhombomere 4/5 boundary. The staining hid Egr2 lacZ staining in rhombomere 3 (see assay MGI:5436312).
Specimen Label: 4F
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1340307
Assay Type: RNA in situ
Annotation Date: 1999-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607312
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:1340377
Age: embryonic day 8.0
Image: 1A
Note: Expression is in the neuroepithelium caudal to the preotic sulcus. Based on comparison to Egr2 expression, Crabp1 is expressed in future rhombomere 4.
Specimen Label: 1A
Detected: true
Specimen Num: 1
Genotype
Symbol: Egr2/Egr2
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Egr2/Egr2
Background: B6.Cg-Egr2
Zygosity: hm
Has Mutant Allele: true
DO Term
GXD Expression
Probe: MGI:5436064
Assay Type: RNA in situ
Annotation Date: 2012-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3282012
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:5436256
Age: embryonic day 8.0
Image: 1H
Note: The stripes of expression in prospective rhombomeres 3 and 5 broadened and formed sharp boundaries. The domains coincided with Egr2 (Krox-20 lacZ staining). Expression was downregulated in rhombomere 4, but persisted at low level in 2 and dorsally in 6.
Specimen Label: 1H
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:17719
Assay Type: RNA in situ
Annotation Date: 1999-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:1335751
Age: embryonic day 7.75
Image: 2.B
Note: A broad domain of expression is seen in the hindbrain. Higher levels of expression are coincident with the domain of Egr2 (Krox20) expression; lower levels extend to a boundary in the posterior hindbrain.
Specimen Label: 2.B
Detected: true
Specimen Num: 2
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Allele
Name: regulatory region 102; targeted mutation 1.1, Mouse Clinical Institute
Allele Type: Targeted
Attribute String: Conditional ready, Modified regulatory region
Allele
Name: regulatory region 102; targeted mutation 1.2, Mouse Clinical Institute
Allele Type: Targeted
Attribute String: Modified regulatory region
Protein Domain
Type: Domain
Description: Wilm's tumour (WT) is an embryonal malignancy of the kidney, affecting around 1 in 10,000 infants. It occurs in both sporadic and hereditary forms. Inactivation of WT1 is one of the causes of Wilm's tumour. Defects in the WT1 gene are also associated with Denys-Drash Syndrome (DDS), which is characterised by typical nephropathy and genital abnormalities. The WT1 gene product shows similarity to the zinc fingers of the mammalian growth regulated EGR1 and EGR2 proteins [, , , ].
Publication
First Author: Belin S
Year: 2019
Journal: Hum Mol Genet
Title: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy.
Volume: 28
Issue: 8
Pages: 1260-1273
Strain
Attribute String: mutant stock, targeted mutation
Strain
Attribute String: mutant stock, targeted mutation
Genotype
Symbol: Rr102/Rr102
Background: involves: C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
Protein Domain
Type: Family
Description: Wilm's tumour (WT) is an embryonal malignancy of the kidney, affecting around 1 in 10,000 infants. It occurs in both sporadic and hereditary forms. Inactivation of WT1 is one of the causes of Wilm's tumour. Defects in the WT1 gene are also associated with Denys-Drash Syndrome (DDS), which is characterised by typical nephropathy and genital abnormalities. The WT1 gene product shows similarity to the zinc fingers of the mammalian growth regulated EGR1 and EGR2 proteins [, , , ].This entry represents a Wilm's tumour protein.
Allele
Name: transgene insertion, John Svaren
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion D, John Svaren
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion E, John Svaren
Allele Type: Transgenic
Attribute String: Reporter
Publication
First Author: Buckler AJ
Year: 1991
Journal: Mol Cell Biol
Title: Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development.
Volume: 11
Issue: 3
Pages: 1707-12
Publication
First Author: Rauscher FJ 3rd
Year: 1993
Journal: FASEB J
Title: The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor.
Volume: 7
Issue: 10
Pages: 896-903
Publication
First Author: Gessler M
Year: 1990
Journal: Nature
Title: Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping.
Volume: 343
Issue: 6260
Pages: 774-8
Publication
First Author: Little MH
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Zinc finger point mutations within the WT1 gene in Wilms tumor patients.
Volume: 89
Issue: 11
Pages: 4791-5
Publication
First Author: Jiang Y
Year: 2014
Journal: Cancer Discov
Title: Tracing the roots of cancer evolution.
Volume: 4
Issue: 9
Pages: 995-7
Genotype
Symbol: Rr102/Rr102<+> Rr111/Rr111<+>
Background: involves: C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Rengarajan J
Year: 2000
Journal: Immunity
Title: Sequential involvement of NFAT and Egr transcription factors in FasL regulation.
Volume: 12
Issue: 3
Pages: 293-300
Publication
First Author: Patwardhan S
Year: 1991
Journal: Oncogene
Title: EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.
Volume: 6
Issue: 6
Pages: 917-28
Publication
First Author: Ayuso-García P
Year: 2024
Journal: Sci Adv
Title: Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination.
Volume: 10
Issue: 15
Pages: eadm7600
Publication
First Author: He Y
Year: 2010
Journal: Nat Neurosci
Title: Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination.
Volume: 13
Issue: 12
Pages: 1472-80
HT Experiment
Series Id: GSE14242
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Tourtellotte WG
Year: 1998
Journal: Nat Genet
Title: Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.
Volume: 20
Issue: 1
Pages: 87-91
Publication
First Author: Hu Q
Year: 2022
Journal: Diabetes
Title: Obesity-Induced miR-455 Upregulation Promotes Adaptive Pancreatic β-Cell Proliferation Through the CPEB1/CDKN1B Pathway.
Volume: 71
Issue: 3
Pages: 394-411
Publication
First Author: Bedel R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity.
Volume: 111
Issue: 1
Pages: E119-28
Publication
First Author: Liu S
Year: 2009
Journal: Mol Endocrinol
Title: Novel regulators of Fgf23 expression and mineralization in Hyp bone.
Volume: 23
Issue: 9
Pages: 1505-18
Publication
First Author: Märklin M
Year: 2017
Journal: Nat Commun
Title: NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.
Volume: 8
Issue: 1
Pages: 755
Publication  
First Author: Torres OV
Year: 2015
Journal: Sci Rep
Title: CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens.
Volume: 5
Pages: 13396
Publication
First Author: Tourtellotte WG
Year: 2000
Journal: Mol Cell Biol
Title: Functional compensation by Egr4 in Egr1-dependent luteinizing hormone regulation and Leydig cell steroidogenesis.
Volume: 20
Issue: 14
Pages: 5261-8
Publication  
First Author: Li C
Year: 2011
Journal: Neuroscience
Title: Microarray analysis of gene expression changes in the brains of NR2B-induced memory-enhanced mice.
Volume: 197
Pages: 121-31
Publication
First Author: Hong J
Year: 2024
Journal: Glia
Title: PMP2 regulates myelin thickening and ATP production during remyelination.
Volume: 72
Issue: 5
Pages: 885-898
Publication
First Author: Hung H
Year: 2012
Journal: J Neurosci
Title: The nucleosome remodeling and deacetylase chromatin remodeling (NuRD) complex is required for peripheral nerve myelination.
Volume: 32
Issue: 5
Pages: 1517-27
Publication
First Author: Ryu EJ
Year: 2007
Journal: J Neurosci
Title: Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss.
Volume: 27
Issue: 43
Pages: 11552-9
Publication  
First Author: Hastings KT
Year: 2017
Journal: Mol Immunol
Title: Nab2 maintains thymus cellularity with aging and stress.
Volume: 85
Pages: 185-195
Publication
First Author: Tang Y
Year: 2015
Journal: Cardiovasc Res
Title: MicroRNA-150 protects the mouse heart from ischaemic injury by regulating cell death.
Volume: 106
Issue: 3
Pages: 387-97
Publication  
First Author: Benturquia N
Year: 2008
Journal: Brain Res
Title: Involvement of D1 dopamine receptor in MDMA-induced locomotor activity and striatal gene expression in mice.
Volume: 1211
Pages: 1-5
Publication
First Author: Shieh JT
Year: 2011
Journal: PLoS One
Title: Elevated miR-499 levels blunt the cardiac stress response.
Volume: 6
Issue: 5
Pages: e19481
Publication
First Author: Salotti J
Year: 2015
Journal: Mol Cell Biol
Title: An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer.
Volume: 35
Issue: 5
Pages: 866-83
Publication
First Author: Sun JJ
Year: 2017
Journal: Sci Rep
Title: Embryonic hindbrain patterning genes delineate distinct cardio-respiratory and metabolic homeostatic populations in the adult.
Volume: 7
Issue: 1
Pages: 9117