| Type |
Details |
Score |
| Publication |
| First Author: |
Jacob JB |
| Year: |
2010 |
| Journal: |
Cancer Res |
| Title: |
Combining human and rat sequences in her-2 DNA vaccines blunts immune tolerance and drives antitumor immunity. |
| Volume: |
70 |
| Issue: |
1 |
| Pages: |
119-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Troise F |
| Year: |
2024 |
| Journal: |
Mol Ther Oncol |
| Title: |
Prime and pull of TÂ cell responses against cancer-exogenous antigens is effective against CPI-resistant tumors. |
| Volume: |
32 |
| Issue: |
1 |
| Pages: |
200760 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transgenic, mutant strain, coisogenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Finkle D |
| Year: |
2004 |
| Journal: |
Clin Cancer Res |
| Title: |
HER2-targeted therapy reduces incidence and progression of midlife mammary tumors in female murine mammary tumor virus huHER2-transgenic mice. |
| Volume: |
10 |
| Issue: |
7 |
| Pages: |
2499-511 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li J |
| Year: |
2019 |
| Journal: |
Sci Transl Med |
| Title: |
CD3 bispecific antibody-induced cytokine release is dispensable for cytotoxic T cell activity. |
| Volume: |
11 |
| Issue: |
508 |
|
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2<+> Nrg1/Nrg1<+> |
| Background: |
involves: 129P2/OlaHsd |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2 |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * BALB/c |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * BALB/c |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * BALB/c |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * BALB/c |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2 |
| Background: |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2 |
| Background: |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2 |
| Background: |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2 |
| Background: |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(MMTV-Erbb2)NF1Mul/? |
| Background: |
involves: CD-1 * FVB/N |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(MMTV-Erbb2)NB1Mul/? |
| Background: |
involves: FVB/N |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(MMTV-Erbb2)NF1Mul/? |
| Background: |
involves: FVB/N |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(MMTV-Erbb2)NF1Mul/? |
| Background: |
FVB/N-Tg(MMTV-Erbb2)NF1Mul |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pds5b/? |
| Background: |
involves: C3H * C57BL/6 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Dock1/Dock1<+> Tg(MMTV-Erbb2*,-cre)1Mul/? |
| Background: |
involves: C57BL/6 * FVB/NJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Dock1/Dock1 Tg(MMTV-Erbb2*,-cre)1Mul/? |
| Background: |
involves: C57BL/6 * FVB/NJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(MMTV-ERBB2)5Erick/? |
| Background: |
FVB/N-Tg(MMTV-ERBB2)5Erick |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Erbb2-Erbb2)NN60Led/? |
| Background: |
involves: FVB/N |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Erbb2-Erbb2*V664E)#Led/? |
| Background: |
involves: FVB/N |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2<+> |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * BALB/c |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Erbb2/Erbb2<+> |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * BALB/c |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim YS |
| Year: |
2023 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
An unanticipated discourse of HB-EGF with VANGL2 signaling during embryo implantation. |
| Volume: |
120 |
| Issue: |
20 |
| Pages: |
e2302937120 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Young CD |
| Year: |
2008 |
| Journal: |
Breast Cancer Res |
| Title: |
Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3. |
| Volume: |
10 |
| Issue: |
4 |
| Pages: |
R70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuang X |
| Year: |
2024 |
| Journal: |
PLoS One |
| Title: |
USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity. |
| Volume: |
19 |
| Issue: |
1 |
| Pages: |
e0290837 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carraway KL 3rd |
| Year: |
2006 |
| Journal: |
Cancer Cell |
| Title: |
Co-opted integrin signaling in ErbB2-induced mammary tumor progression. |
| Volume: |
10 |
| Issue: |
2 |
| Pages: |
93-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuznetsov SB |
| Year: |
1998 |
| Journal: |
Genetika |
| Title: |
[Chromosome localization and analysis of synteny analysis of some genes in swine, cattle, and sheep (Artiodactyla)]. |
| Volume: |
34 |
| Issue: |
9 |
| Pages: |
1200-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ursini-Siegel J |
| Year: |
2007 |
| Journal: |
Nat Rev Cancer |
| Title: |
Insights from transgenic mouse models of ERBB2-induced breast cancer. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
389-97 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
177
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1217
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
674
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
208
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
162
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
695
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schug TT |
| Year: |
2007 |
| Journal: |
Cell |
| Title: |
Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors. |
| Volume: |
129 |
| Issue: |
4 |
| Pages: |
723-33 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, transgenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, transgenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Henry MD |
| Year: |
2004 |
| Journal: |
Oncogene |
| Title: |
Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice. |
| Volume: |
23 |
| Issue: |
41 |
| Pages: |
6980-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Costa C |
| Year: |
2015 |
| Journal: |
Cancer Cell |
| Title: |
Measurement of PIP3 levels reveals an unexpected role for p110β in early adaptive responses to p110α-specific inhibitors in luminal breast cancer. |
| Volume: |
27 |
| Issue: |
1 |
| Pages: |
97-108 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu H |
| Year: |
2006 |
| Journal: |
Cancer Res |
| Title: |
The tumor antigen repertoire identified in tumor-bearing neu transgenic mice predicts human tumor antigens. |
| Volume: |
66 |
| Issue: |
19 |
| Pages: |
9754-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jin Z |
| Year: |
2002 |
| Journal: |
J Nutr |
| Title: |
Soy isoflavones increase latency of spontaneous mammary tumors in mice. |
| Volume: |
132 |
| Issue: |
10 |
| Pages: |
3186-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Elangovan S |
| Year: |
2014 |
| Journal: |
Cancer Res |
| Title: |
The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival. |
| Volume: |
74 |
| Issue: |
4 |
| Pages: |
1166-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hartman ZC |
| Year: |
2011 |
| Journal: |
Cancer Res |
| Title: |
HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis. |
| Volume: |
71 |
| Issue: |
13 |
| Pages: |
4380-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kryza D |
| Year: |
2023 |
| Journal: |
EMBO Mol Med |
| Title: |
From netrin-1-targeted SPECT/CT to internal radiotherapy for management of advanced solid tumors. |
| Volume: |
15 |
| Issue: |
4 |
| Pages: |
e16732 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Landis MD |
| Year: |
2005 |
| Journal: |
Oncogene |
| Title: |
Gene expression profiling of cancer progression reveals intrinsic regulation of transforming growth factor-beta signaling in ErbB2/Neu-induced tumors from transgenic mice. |
| Volume: |
24 |
| Issue: |
33 |
| Pages: |
5173-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Worschech A |
| Year: |
2008 |
| Journal: |
Cancer Res |
| Title: |
Signatures associated with rejection or recurrence in HER-2/neu-positive mammary tumors. |
| Volume: |
68 |
| Issue: |
7 |
| Pages: |
2436-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gómez-Vecino A |
| Year: |
2023 |
| Journal: |
Cells |
| Title: |
Intermediate Molecular Phenotypes to Identify Genetic Markers of Anthracycline-Induced Cardiotoxicity Risk. |
| Volume: |
12 |
| Issue: |
15 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li YJ |
| Year: |
2015 |
| Journal: |
Oncotarget |
| Title: |
Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic mice. |
| Volume: |
6 |
| Issue: |
35 |
| Pages: |
36943-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Quaglino E |
| Year: |
2004 |
| Journal: |
J Clin Invest |
| Title: |
Concordant morphologic and gene expression data show that a vaccine halts HER-2/neu preneoplastic lesions. |
| Volume: |
113 |
| Issue: |
5 |
| Pages: |
709-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muraoka-Cook RS |
| Year: |
2006 |
| Journal: |
Oncogene |
| Title: |
Activated type I TGFbeta receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression. |
| Volume: |
25 |
| Issue: |
24 |
| Pages: |
3408-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liby K |
| Year: |
2008 |
| Journal: |
Clin Cancer Res |
| Title: |
Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268. |
| Volume: |
14 |
| Issue: |
14 |
| Pages: |
4556-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zacarias-Fluck MF |
| Year: |
2015 |
| Journal: |
J Natl Cancer Inst |
| Title: |
Effect of cellular senescence on the growth of HER2-positive breast cancers. |
| Volume: |
107 |
| Issue: |
5 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Astolfi A |
| Year: |
2005 |
| Journal: |
Am J Pathol |
| Title: |
Gene expression analysis of immune-mediated arrest of tumorigenesis in a transgenic mouse model of HER-2/neu-positive basal-like mammary carcinoma. |
| Volume: |
166 |
| Issue: |
4 |
| Pages: |
1205-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sacco MG |
| Year: |
2003 |
| Journal: |
Gene Ther |
| Title: |
Combined antiestrogen, antiangiogenic and anti-invasion therapy inhibits primary and metastatic tumor growth in the MMTVneu model of breast cancer. |
| Volume: |
10 |
| Issue: |
22 |
| Pages: |
1903-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Anisimov VN |
| Year: |
2005 |
| Journal: |
Bull Exp Biol Med |
| Title: |
Metformin decelerates aging and development of mammary tumors in HER-2/neu transgenic mice. |
| Volume: |
139 |
| Issue: |
6 |
| Pages: |
721-3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kurt RA |
| Year: |
2003 |
| Journal: |
Breast Cancer Res Treat |
| Title: |
Altered chemokine receptor sensitivity in FVBN202 rat neu transgenic mice. |
| Volume: |
77 |
| Issue: |
3 |
| Pages: |
225-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Josefsson A |
| Year: |
2016 |
| Journal: |
Cancer Res |
| Title: |
Imaging, Biodistribution, and Dosimetry of Radionuclide-Labeled PD-L1 Antibody in an Immunocompetent Mouse Model of Breast Cancer. |
| Volume: |
76 |
| Issue: |
2 |
| Pages: |
472-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rich BS |
| Year: |
2014 |
| Journal: |
Sci Rep |
| Title: |
Endogenous antibodies for tumor detection. |
| Volume: |
4 |
|
| Pages: |
5088 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rowswell-Turner RB |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
Chronic chemoimmunotherapy achieves cure of spontaneous murine mammary tumors via persistent blockade of posttherapy counter-regulation. |
| Volume: |
187 |
| Issue: |
8 |
| Pages: |
4109-18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang YA |
| Year: |
2002 |
| Journal: |
J Clin Invest |
| Title: |
Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects. |
| Volume: |
109 |
| Issue: |
12 |
| Pages: |
1607-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Knutson KL |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice. |
| Volume: |
177 |
| Issue: |
1 |
| Pages: |
84-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ménard S |
| Year: |
2000 |
| Journal: |
Cancer Res |
| Title: |
Tamoxifen chemoprevention of a hormone-independent tumor in the proto-neu transgenic mice model. |
| Volume: |
60 |
| Issue: |
2 |
| Pages: |
273-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang X |
| Year: |
2003 |
| Journal: |
Cancer Res |
| Title: |
Hormonal and dietary modulation of mammary carcinogenesis in mouse mammary tumor virus-c-erbB-2 transgenic mice. |
| Volume: |
63 |
| Issue: |
10 |
| Pages: |
2425-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ercolini AM |
| Year: |
2005 |
| Journal: |
J Exp Med |
| Title: |
Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response. |
| Volume: |
201 |
| Issue: |
10 |
| Pages: |
1591-602 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Anisimov VN |
| Year: |
2005 |
| Journal: |
Exp Gerontol |
| Title: |
Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. |
| Volume: |
40 |
| Issue: |
8-9 |
| Pages: |
685-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park KH |
| Year: |
2008 |
| Journal: |
Cancer Res |
| Title: |
Insulin-like growth factor-binding protein-2 is a target for the immunomodulation of breast cancer. |
| Volume: |
68 |
| Issue: |
20 |
| Pages: |
8400-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Khan AUH |
| Year: |
2021 |
| Journal: |
Int J Mol Sci |
| Title: |
Effects of Chronic Low-Dose Internal Radiation on Immune-Stimulatory Responses in Mice. |
| Volume: |
22 |
| Issue: |
14 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Davis VL |
| Year: |
2008 |
| Journal: |
Cancer Res |
| Title: |
Black cohosh increases metastatic mammary cancer in transgenic mice expressing c-erbB2. |
| Volume: |
68 |
| Issue: |
20 |
| Pages: |
8377-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jiang Y |
| Year: |
2016 |
| Journal: |
Cancer Res |
| Title: |
A Sucrose-Enriched Diet Promotes Tumorigenesis in Mammary Gland in Part through the 12-Lipoxygenase Pathway. |
| Volume: |
76 |
| Issue: |
1 |
| Pages: |
24-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muller AJ |
| Year: |
2005 |
| Journal: |
Nat Med |
| Title: |
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. |
| Volume: |
11 |
| Issue: |
3 |
| Pages: |
312-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gonzalez-Suarez E |
| Year: |
2010 |
| Journal: |
Nature |
| Title: |
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis. |
| Volume: |
468 |
| Issue: |
7320 |
| Pages: |
103-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rowse GJ |
| Year: |
1998 |
| Journal: |
Cancer Res |
| Title: |
Genetic modulation of neu proto-oncogene-induced mammary tumorigenesis. |
| Volume: |
58 |
| Issue: |
12 |
| Pages: |
2675-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liby K |
| Year: |
2006 |
| Journal: |
Clin Cancer Res |
| Title: |
The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer. |
| Volume: |
12 |
| Issue: |
19 |
| Pages: |
5902-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tomblyn S |
| Year: |
2009 |
| Journal: |
Int J Oncol |
| Title: |
Combination therapy using three novel prolactin receptor antagonist-based fusion proteins effectively inhibits tumor recurrence and metastasis in HER2/neu transgenic mice. |
| Volume: |
34 |
| Issue: |
4 |
| Pages: |
1139-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu H |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade. |
| Volume: |
184 |
| Issue: |
9 |
| Pages: |
5360-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rossi EL |
| Year: |
2017 |
| Journal: |
Cancer Res |
| Title: |
Energy Balance Modulation Impacts Epigenetic Reprogramming, ERα and ERβ Expression, and Mammary Tumor Development in MMTV-neu Transgenic Mice. |
| Volume: |
77 |
| Issue: |
9 |
| Pages: |
2500-2511 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rolla S |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
Distinct and non-overlapping T cell receptor repertoires expanded by DNA vaccination in wild-type and HER-2 transgenic BALB/c mice. |
| Volume: |
177 |
| Issue: |
11 |
| Pages: |
7626-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Casado-Medrano V |
| Year: |
2016 |
| Journal: |
Oncotarget |
| Title: |
A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression. |
| Volume: |
7 |
| Issue: |
19 |
| Pages: |
28301-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mamessier E |
| Year: |
2011 |
| Journal: |
Cancer Res |
| Title: |
Human breast tumor cells induce self-tolerance mechanisms to avoid NKG2D-mediated and DNAM-mediated NK cell recognition. |
| Volume: |
71 |
| Issue: |
21 |
| Pages: |
6621-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu JC |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER2+:ERα- breast cancer. |
| Volume: |
109 |
| Issue: |
15 |
| Pages: |
5832-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deng T |
| Year: |
2014 |
| Journal: |
Cancer Res |
| Title: |
shRNA kinome screen identifies TBK1 as a therapeutic target for HER2+ breast cancer. |
| Volume: |
74 |
| Issue: |
7 |
| Pages: |
2119-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mosley JD |
| Year: |
2007 |
| Journal: |
Mol Cancer Ther |
| Title: |
Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer. |
| Volume: |
6 |
| Issue: |
8 |
| Pages: |
2188-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Davies MP |
| Year: |
1996 |
| Journal: |
Oncogene |
| Title: |
Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours. |
| Volume: |
13 |
| Issue: |
8 |
| Pages: |
1631-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gonzalez ME |
| Year: |
2014 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
EZH2 expands breast stem cells through activation of NOTCH1 signaling. |
| Volume: |
111 |
| Issue: |
8 |
| Pages: |
3098-103 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wolpoe ME |
| Year: |
2003 |
| Journal: |
J Immunol |
| Title: |
HER-2/neu-specific monoclonal antibodies collaborate with HER-2/neu-targeted granulocyte macrophage colony-stimulating factor secreting whole cell vaccination to augment CD8+ T cell effector function and tumor-free survival in Her-2/neu-transgenic mice. |
| Volume: |
171 |
| Issue: |
4 |
| Pages: |
2161-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo HB |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Specific posttranslational modification regulates early events in mammary carcinoma formation. |
| Volume: |
107 |
| Issue: |
49 |
| Pages: |
21116-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lo PK |
| Year: |
2012 |
| Journal: |
Oncogene |
| Title: |
CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling. |
| Volume: |
31 |
| Issue: |
21 |
| Pages: |
2614-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nair RE |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
Chronic immune therapy induces a progressive increase in intratumoral T suppressor activity and a concurrent loss of tumor-specific CD8+ T effectors in her-2/neu transgenic mice bearing advanced spontaneous tumors. |
| Volume: |
176 |
| Issue: |
12 |
| Pages: |
7325-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kmieciak M |
| Year: |
2007 |
| Journal: |
Eur J Immunol |
| Title: |
HER-2/neu antigen loss and relapse of mammary carcinoma are actively induced by T cell-mediated anti-tumor immune responses. |
| Volume: |
37 |
| Issue: |
3 |
| Pages: |
675-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reilly RT |
| Year: |
2000 |
| Journal: |
Cancer Res |
| Title: |
HER-2/neu is a tumor rejection target in tolerized HER-2/neu transgenic mice. |
| Volume: |
60 |
| Issue: |
13 |
| Pages: |
3569-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Knutson KL |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
Immunoediting of cancers may lead to epithelial to mesenchymal transition. |
| Volume: |
177 |
| Issue: |
3 |
| Pages: |
1526-33 |
|
•
•
•
•
•
|