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Search results 1301 to 1400 out of 1513 for Gdnf

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Type Details Score
Publication
31149899 | J:276779
   
First Author: Sharma M
Year: 2019
Journal: Elife
Title: Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF.
Volume: 8
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Publication
9192684 | -
First Author: Creedon DJ
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons.
Volume: 94
Issue: 13
Pages: 7018-23
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Publication
9756328 | J:49728
First Author: Cheng FC
Year: 1998
Journal: Neurosci Lett
Title: Glial cell line-derived neurotrophic factor protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity in C57BL/6 mice.
Volume: 252
Issue: 2
Pages: 87-90
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Protein
A0A7R7T2G6
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
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Protein Domain
IPR017372 | Glial_neurotroph_fac_rcpt_a1/2
Type: Family
Description: Glial cell line-derived neurotrophic factor (GDNF) and its related factorsneurturin (NTN), artemin (ART) and persephin (PSP), are members of the GDNFfamily of neurotrophic factors. They form a sub-group in the transforming growth factor-beta (TGF-beta) superfamily. These factors are involved inthe promotion of neurone survival, exerting their effects through specific receptors.The GDNF family receptors (GFRs) are glycosyl-phosphatidylinositol-linked,cell surface receptors []. Four receptor subtypes, termed GFRalpha-1 to 4, are currently recognised. GFRalpha-1 and 2 are activated by GDNF and NTN respectively, although some degree of ligand promiscuity is thought to occur []. Homologues for these receptor subtypes have been cloned from mammalian and avian tissue. The principal ligand for GFRalpha-3 is artemin. This receptor subtype is currently described only in mammals []. GFRalpha-4 is activated by persephin and has so far only been found in chicken []. This entry is general for types 1 to 3.Activation of GFR family members triggers their interaction with the membrane-bound receptor kinase Ret. This induces Ret homo-dimerisation, triggering a cascade of intracellular signalling events such as the activation of the Ras-mitogen-activated protein kinase (MAPK), phosphoinositol-3-kinase (PI3K), Jun N-terminal kinase (JNK) and phospholipase C gamma (PLC gamma) dependent pathways [].
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Protein Domain
IPR003438 | GDNF_rcpt
Type: Family
Description: Glial cell line-derived neurotrophic factor (GDNF) and its related factorsneurturin (NTN), artemin (ART) and persephin (PSP), are members of the GDNFfamily of neurotrophic factors. They form a sub-group in the transforming growth factor-beta (TGF-beta) superfamily. These factors are involved inthe promotion of neurone survival, exerting their effects through specific receptors.The GDNF family receptors (GFRs) are glycosyl-phosphatidylinositol-linked,cell surface receptors []. Four receptor subtypes, termed GFRalpha-1 to 4, are currently recognised. GFRalpha-1 and 2 are activated by GDNF and NTN respectively, although some degree of ligand promiscuity is thought to occur []. Homologues for these receptor subtypes have been cloned from mammalian and avian tissue. The principal ligand for GFRalpha-3 is artemin. This receptor subtype is currently described only in mammals []. GFRalpha-4 is activated by persephin and has so far only been found in chicken []. This entry is general for types 1 to 3.Activation of GFR family members triggers their interaction with the membrane-bound receptor kinase Ret. This induces Ret homo-dimerisation, triggering a cascade of intracellular signalling events such as the activation of the Ras-mitogen-activated protein kinase (MAPK), phosphoinositol-3-kinase (PI3K), Jun N-terminal kinase (JNK) and phospholipase C gamma (PLC gamma)dependent pathways [].
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HT Experiment
GSE156905 | scRNA-sequencing reveals new enteric nervous system roles for GDNF, NRTN, and TBX3
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE158285 | RNA Helicase DDX5 Acts as a Critical Regulator for Gonocyte Survival in Neonatal Mouse
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:3827124 | B6;CBA-Tg(tetO-Gdnf,lacZ)14Brke/Mmmh
Attribute String: mutant stock, transgenic
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Genotype
Genotype
Symbol: Bid/Bid Gdnf/Gdnf<+>
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gdnf/Gdnf<+> Itga8/Itga8
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gdnf/Gdnf<+> Itga8/Itga8<+>
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gdnf/Gdnf<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gdnf/Gdnf<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Spry1/Spry1<+>
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Protein Domain
IPR003504 | GDNF_rcpt_a2
Type: Family
Description: Glial cell line-derived neurotrophic factor (GDNF) and its related factorsneurturin (NTN), artemin (ART) and persephin (PSP), are members of the GDNFfamily of neurotrophic factors. They form a sub-group in the transforming growth factor-beta (TGF-beta) superfamily. These factors are involved inthe promotion of neurone survival, exerting their effects through specific receptors.The GDNF family receptors (GFRs) are glycosyl-phosphatidylinositol-linked,cell surface receptors []. Four receptor subtypes, termed GFRalpha-1 to 4, are currently recognised. Homologues for the GFRalpha-2 receptor subtype have been cloned from mammalian and avian tissue. The receptor is preferentially activated by neurturin, although there is evidence that GFRalpha-2 can also bindGDNF if pre-coupled to its effector molecule [].Activation of GFRalpha-2 triggers its interaction with the membrane-bound receptor kinase Ret. This induces Ret homo-dimerisation, triggering a cascade of intracellular signalling events such as the activation of the Ras-mitogen-activated protein kinase (MAPK), phosphoinositol-3-kinase (PI3K), Jun N-terminal kinase (JNK) and phospholipase C gamma (PLC gamma) dependent pathways [].
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Protein Domain
IPR003505 | GDNF_rcpt_A3
Type: Family
Description: Glial cell line-derived neurotrophic factor (GDNF) and its related factorsneurturin (NTN), artemin (ART) and persephin (PSP), are members of the GDNFfamily of neurotrophic factors. They form a sub-group in the transforming growth factor-beta (TGF-beta) superfamily. These factors are involved inthe promotion of neurone survival, exerting their effects through specific receptors.The GDNF family receptors (GFRs) are glycosyl-phosphatidylinositol-linked,cell surface receptors []. Four receptor subtypes, termed GFRalpha-1 to 4, are currently recognised. GFRalpha-3 has been cloned from mammalian tissue []. It represents the least conserved member of the GFR family in terms of amino acid sequence, and is activated by artemin [].Activation of GFR family members triggers their interaction with the membrane-bound receptor kinase Ret. This induces Ret homo-dimerisation, triggering a cascade of intracellular signalling events such as the activation of the Ras-mitogen-activated protein kinase (MAPK), phosphoinositol-3-kinase (PI3K), Jun N-terminal kinase (JNK) and phospholipase C gamma (PLC gamma) dependent pathways [].
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Genotype
Genotype
Symbol: Gdnf/Gdnf Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129S1/Sv * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gdnf/Gdnf Egr3/Egr3<+>
Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
20659772 | J:357693
First Author: Yamasaki R
Year: 2010
Journal: J Neuroimmunol
Title: Restoration of microglial function by granulocyte-colony stimulating factor in ALS model mice.
Volume: 229
Issue: 1-2
Pages: 51-62
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Publication
19580811 | J:152095
First Author: Li J
Year: 2009
Journal: FEBS Lett
Title: Autocrine regulation of early embryonic development by the artemin-GFRA3 (GDNF family receptor-alpha 3) signaling system in mice.
Volume: 583
Issue: 15
Pages: 2479-85
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Publication
25242331 | -
First Author: Goodman KM
Year: 2014
Journal: Cell Rep
Title: RET recognition of GDNF-GFRα1 ligand by a composite binding site promotes membrane-proximal self-association.
Volume: 8
Issue: 6
Pages: 1894-1904
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Publication
14659533 | J:127896
First Author: Zwick M
Year: 2003
Journal: Pain
Title: Transgenic mice possessing increased numbers of nociceptors do not exhibit increased behavioral sensitivity in models of inflammatory and neuropathic pain.
Volume: 106
Issue: 3
Pages: 491-500
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Publication
34407418 | J:310652
First Author: Mori Y
Year: 2021
Journal: Cell Rep
Title: Cdc42 is required for male germline niche development in mice.
Volume: 36
Issue: 7
Pages: 109550
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Publication
11900972 | J:184664
First Author: Tadokoro Y
Year: 2002
Journal: Mech Dev
Title: Homeostatic regulation of germinal stem cell proliferation by the GDNF/FSH pathway.
Volume: 113
Issue: 1
Pages: 29-39
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Publication
22304922 | J:180801
First Author: Bonanomi D
Year: 2012
Journal: Cell
Title: Ret is a multifunctional coreceptor that integrates diffusible- and contact-axon guidance signals.
Volume: 148
Issue: 3
Pages: 568-82
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Publication
17553423 | J:126484
First Author: Luo W
Year: 2007
Journal: Neuron
Title: A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.
Volume: 54
Issue: 5
Pages: 739-54
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Publication
25108913 | J:215832
First Author: Chai G
Year: 2014
Journal: Nat Neurosci
Title: Celsr3 is required in motor neurons to steer their axons in the hindlimb.
Volume: 17
Issue: 9
Pages: 1171-9
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Publication
17785448 | J:129070
First Author: Gong KQ
Year: 2007
Journal: Mol Cell Biol
Title: A Hox-Eya-Pax complex regulates early kidney developmental gene expression.
Volume: 27
Issue: 21
Pages: 7661-8
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Publication
20298786 | J:163048
First Author: Kong L
Year: 2010
Journal: Neurobiol Dis
Title: Neuroprotective effect of overexpression of thioredoxin on photoreceptor degeneration in Tubby mice.
Volume: 38
Issue: 3
Pages: 446-55
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Publication
9728913 | J:49471
First Author: Enomoto H
Year: 1998
Journal: Neuron
Title: GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys.
Volume: 21
Issue: 2
Pages: 317-24
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Publication
10069331 | J:53284
First Author: Rossi J
Year: 1999
Journal: Neuron
Title: Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha2, a functional neurturin receptor.
Volume: 22
Issue: 2
Pages: 243-52
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Publication
11050250 | J:65427
First Author: Nanobashvili A
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor alpha 2.
Volume: 97
Issue: 22
Pages: 12312-7
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Publication
15621530 | J:95805
First Author: Shakya R
Year: 2005
Journal: Dev Cell
Title: The role of GDNF/Ret signaling in ureteric bud cell fate and branching morphogenesis.
Volume: 8
Issue: 1
Pages: 65-74
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Publication
22753894 | J:190757
First Author: Fontana X
Year: 2012
Journal: J Cell Biol
Title: c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling.
Volume: 198
Issue: 1
Pages: 127-41
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Publication
9115735 | J:39084
First Author: Morin X
Year: 1997
Journal: Neuron
Title: Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a.
Volume: 18
Issue: 3
Pages: 411-23
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Publication
20691905 | J:167931
First Author: Hobbs RM
Year: 2010
Journal: Cell
Title: Plzf regulates germline progenitor self-renewal by opposing mTORC1.
Volume: 142
Issue: 3
Pages: 468-79
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Publication
12160745 | J:78008
First Author: Honma Y
Year: 2002
Journal: Neuron
Title: Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons.
Volume: 35
Issue: 2
Pages: 267-82
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Publication
36001956 | J:328108
First Author: Klein AB
Year: 2022
Journal: Cell Rep
Title: The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance.
Volume: 40
Issue: 8
Pages: 111258
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Publication
19150499 | J:147305
First Author: Ramaswamy S
Year: 2009
Journal: Neurobiol Dis
Title: Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease.
Volume: 34
Issue: 1
Pages: 40-50
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Publication
30264295 | J:314823
First Author: Zhang H
Year: 2019
Journal: Mol Neurobiol
Title: Upregulation of MicroRNA miR-9 Is Associated with Microcephaly and Zika Virus Infection in Mice.
Volume: 56
Issue: 6
Pages: 4072-4085
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Publication
18497757 | J:154274
First Author: Encinas M
Year: 2008
Journal: Cell Death Differ
Title: Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons.
Volume: 15
Issue: 9
Pages: 1510-21
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Publication
10673327 | J:60717
First Author: Rosenblad C
Year: 2000
Journal: Mol Cell Neurosci
Title: In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin.
Volume: 15
Issue: 2
Pages: 199-214
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Publication
9465906 | J:45385
First Author: Puliti A
Year: 1997
Journal: Cytogenet Cell Genet
Title: Assignment of mouse Gfra1, the homologue of a new human HSCR candidate gene, to the telomeric region of mouse chromosome 19.
Volume: 78
Issue: 3-4
Pages: 291-4
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Publication
14555954 | J:86397
First Author: Chen S
Year: 2003
Journal: Nat Neurosci
Title: Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss.
Volume: 6
Issue: 11
Pages: 1186-93
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Publication
19463953 | J:154250
First Author: Yoong LF
Year: 2009
Journal: Mol Cell Neurosci
Title: GDNF-induced cell signaling and neurite outgrowths are differentially mediated by GFRalpha1 isoforms.
Volume: 41
Issue: 4
Pages: 464-73
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Publication
25947060 | J:222961
First Author: Morimoto H
Year: 2015
Journal: Biol Reprod
Title: ROS-Generating Oxidase Nox3 Regulates the Self-Renewal of Mouse Spermatogonial Stem Cells.
Volume: 92
Issue: 6
Pages: 147
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Publication
27998933 | J:246581
First Author: Chen J
Year: 2017
Journal: Nucleic Acids Res
Title: MicroRNA-202 maintains spermatogonial stem cells by inhibiting cell cycle regulators and RNA binding proteins.
Volume: 45
Issue: 7
Pages: 4142-4157
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Publication
30184485 | J:266774
First Author: Tsai VWW
Year: 2018
Journal: Cell Metab
Title: The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases.
Volume: 28
Issue: 3
Pages: 353-368
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Publication
33589633 | J:304627
First Author: Klein AB
Year: 2021
Journal: Nat Commun
Title: Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise.
Volume: 12
Issue: 1
Pages: 1041
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Publication
27509137 | J:315460
First Author: Tanaka T
Year: 2016
Journal: Stem Cell Reports
Title: The Luteinizing Hormone-Testosterone Pathway Regulates Mouse Spermatogonial Stem Cell Self-Renewal by Suppressing WNT5A Expression in Sertoli Cells.
Volume: 7
Issue: 2
Pages: 279-91
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Publication
33298864 | J:307525
First Author: Cui W
Year: 2020
Journal: Cell Discov
Title: CARF promotes spermatogonial self-renewal and proliferation through Wnt signaling pathway.
Volume: 6
Issue: 1
Pages: 85
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Publication
14522971 | J:87168
First Author: Fukuda N
Year: 2003
Journal: J Biol Chem
Title: Identification of a novel glial cell line-derived neurotrophic factor-inducible gene required for renal branching morphogenesis.
Volume: 278
Issue: 50
Pages: 50386-92
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Publication
21994944 | J:276421
First Author: Geng Z
Year: 2011
Journal: J Biol Chem
Title: Sorting protein-related receptor SorLA controls regulated secretion of glial cell line-derived neurotrophic factor.
Volume: 286
Issue: 48
Pages: 41871-82
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Publication
17611540 | J:306364
First Author: Lindholm P
Year: 2007
Journal: Nature
Title: Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo.
Volume: 448
Issue: 7149
Pages: 73-7
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Publication
9348334 | J:44087
First Author: Yajima S
Year: 1997
Journal: J Neurosci
Title: Cloning and characterization of murine glial cell-derived neurotrophic factor inducible transcription factor (MGIF).
Volume: 17
Issue: 22
Pages: 8657-66
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Publication
20237269 | J:159107
First Author: Golden JP
Year: 2010
Journal: J Neurosci
Title: RET signaling is required for survival and normal function of nonpeptidergic nociceptors.
Volume: 30
Issue: 11
Pages: 3983-94
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Publication
20007774 | J:156489
First Author: Krentz AD
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.
Volume: 106
Issue: 52
Pages: 22323-8
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Publication
21212101 | J:168845
First Author: Reginensi A
Year: 2011
Journal: Hum Mol Genet
Title: SOX9 controls epithelial branching by activating RET effector genes during kidney development.
Volume: 20
Issue: 6
Pages: 1143-53
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Publication
16740658 | J:111053
First Author: Oatley JM
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Identifying genes important for spermatogonial stem cell self-renewal and survival.
Volume: 103
Issue: 25
Pages: 9524-9
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Publication
19369648 | J:152976
First Author: Kubota H
Year: 2009
Journal: Biol Reprod
Title: Spermatogonial stem cells derived from infertile Wv/Wv mice self-renew in vitro and generate progeny following transplantation.
Volume: 81
Issue: 2
Pages: 293-301
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Publication
22745058 | J:185654
First Author: Nagai R
Year: 2012
Journal: Dev Dyn
Title: Dynamics of GFRα1-positive spermatogonia at the early stages of colonization in the recipient testes of W/Wν male mice.
Volume: 241
Issue: 8
Pages: 1374-84
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Publication
17249577 | J:154016
 
First Author: Zencak D
Year: 2006
Journal: Adv Exp Med Biol
Title: BMI1 loss delays photoreceptor degeneration in Rd1 mice. Bmi1 loss and neuroprotection in Rd1 mice.
Volume: 572
Pages: 209-15
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Publication
21360756 | J:169746
First Author: Del Río P
Year: 2011
Journal: Glia
Title: GDNF-induced osteopontin from Müller glial cells promotes photoreceptor survival in the Pde6brd1 mouse model of retinal degeneration.
Volume: 59
Issue: 5
Pages: 821-32
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Publication
23262364 | J:203649
 
First Author: Euteneuer S
Year: 2013
Journal: Mol Cell Neurosci
Title: Glial cell line-derived neurotrophic factor (GDNF) induces neuritogenesis in the cochlear spiral ganglion via neural cell adhesion molecule (NCAM).
Volume: 54
Pages: 30-43
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Publication
11138002 | J:79420
First Author: Batourina E
Year: 2001
Journal: Nat Genet
Title: Vitamin A controls epithelial/mesenchymal interactions through Ret expression.
Volume: 27
Issue: 1
Pages: 74-8
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Publication
17047028 | J:117753
First Author: Clarke JC
Year: 2006
Journal: Hum Mol Genet
Title: Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage.
Volume: 15
Issue: 23
Pages: 3420-8
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Publication
19112489 | J:142876
First Author: Grote D
Year: 2008
Journal: PLoS Genet
Title: Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction.
Volume: 4
Issue: 12
Pages: e1000316
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Publication
19794154 | J:156636
First Author: Tanwar PS
Year: 2010
Journal: Biol Reprod
Title: Constitutive WNT/beta-catenin signaling in murine Sertoli cells disrupts their differentiation and ability to support spermatogenesis.
Volume: 82
Issue: 2
Pages: 422-32
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Publication
29615705 | J:302845
First Author: Chen C
Year: 2018
Journal: Sci Rep
Title: GDNF-expressing macrophages mitigate loss of dopamine neurons and improve Parkinsonian symptoms in MitoPark mice.
Volume: 8
Issue: 1
Pages: 5460
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Publication
23613711 | J:200115
First Author: Dovere L
Year: 2013
Journal: PLoS One
Title: The niche-derived glial cell line-derived neurotrophic factor (GDNF) induces migration of mouse spermatogonial stem/progenitor cells.
Volume: 8
Issue: 4
Pages: e59431
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Publication
17298183 | J:122044
First Author: Kramer ER
Year: 2007
Journal: PLoS Biol
Title: Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system.
Volume: 5
Issue: 3
Pages: e39
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Publication
23678134 | J:296654
First Author: Simanainen U
Year: 2013
Journal: J Endocrinol
Title: Evidence for increased tissue androgen sensitivity in neurturin knockout mice.
Volume: 218
Issue: 2
Pages: 151-63
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Publication
10864957 | J:63174
First Author: Garcès A
Year: 2000
Journal: J Neurosci
Title: GFRalpha 1 is required for development of distinct subpopulations of motoneuron.
Volume: 20
Issue: 13
Pages: 4992-5000
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Publication
11069590 | J:89887
First Author: Rossi J
Year: 2000
Journal: Eur J Neurosci
Title: Distinct roles for GFRalpha1 and GFRalpha2 signalling in different cranial parasympathetic ganglia in vivo.
Volume: 12
Issue: 11
Pages: 3944-52
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Publication
16481427 | J:105756
First Author: Lindfors PH
Year: 2006
Journal: J Neurosci
Title: Deficient nonpeptidergic epidermis innervation and reduced inflammatory pain in glial cell line-derived neurotrophic factor family receptor alpha2 knock-out mice.
Volume: 26
Issue: 7
Pages: 1953-60
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First Author: Kupari J
Year: 2014
Journal: PLoS One
Title: Different requirements for GFRα2-signaling in three populations of cutaneous sensory neurons.
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Year: 2023
Journal: Elife
Title: Age-associated changes in lineage composition of the enteric nervous system regulate gut health and disease.
Volume: 12
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First Author: Wright CM
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: scRNA-Seq Reveals New Enteric Nervous System Roles for GDNF, NRTN, and TBX3.
Volume: 11
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18414682 | J:135153
First Author: Uesaka T
Year: 2008
Journal: J Clin Invest
Title: Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice.
Volume: 118
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Pages: 1890-8
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37508531 | J:339036
 
First Author: Teramoto H
Year: 2023
Journal: Cells
Title: Calcineurin B1 Deficiency Reduces Proliferation, Increases Apoptosis, and Alters Secretion in Enteric Glial Cells of Mouse Small Intestine in Culture.
Volume: 12
Issue: 14
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First Author: Brantley MA Jr
Year: 2008
Journal: J Neurosci
Title: Neurturin-mediated ret activation is required for retinal function.
Volume: 28
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Pages: 4123-35
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First Author: Asai N
Year: 2006
Journal: Development
Title: Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells.
Volume: 133
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Pages: 4507-16
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First Author: Keefe Davis T
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Journal: Mech Dev
Title: Stage specific requirement of Gfrα1 in the ureteric epithelium during kidney development.
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Pages: 506-18
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First Author: Jain S
Year: 2006
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Title: RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice.
Volume: 26
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First Author: Gou-Fàbregas M
Year: 2016
Journal: Sci Rep
Title: 7-dehydrocholesterol efficiently supports Ret signaling in a mouse model of Smith-Opitz-Lemli syndrome.
Volume: 6
Pages: 28534
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21873685 | J:181588
First Author: Lipinski DM
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Title: Assessment of cone survival in response to CNTF, GDNF, and VEGF165b in a novel ex vivo model of end-stage retinitis pigmentosa.
Volume: 52
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Pages: 7340-6
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First Author: Kim D
Year: 2007
Journal: Dev Biol
Title: PTEN modulates GDNF/RET mediated chemotaxis and branching morphogenesis in the developing kidney.
Volume: 307
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Pages: 290-9
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21193524 | J:171165
First Author: Tanaka T
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Journal: Am J Physiol Gastrointest Liver Physiol
Title: Modulation of visceral hypersensitivity by glial cell line-derived neurotrophic factor family receptor &alpha;-3 in colorectal afferents.
Volume: 300
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Pages: G418-24
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First Author: Ryu H
Year: 2011
Journal: Lab Invest
Title: Differential expression of c-Ret in motor neurons versus non-neuronal cells is linked to the pathogenesis of ALS.
Volume: 91
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Pages: 342-52
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First Author: Komiya H
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Title: Ablation of interleukin-19 improves motor function in a mouse model of amyotrophic lateral sclerosis.
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Title: Unchanged Neurotrophic Factors and Their Receptors Correlate With Sparing in Extraocular Muscles in Amyotrophic Lateral Sclerosis.
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Title: Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy.
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Year: 2012
Journal: PLoS One
Title: Regulation of the Na,K-ATPase gamma-subunit FXYD2 by Runx1 and Ret signaling in normal and injured non-peptidergic nociceptive sensory neurons.
Volume: 7
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Pages: e29852
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First Author: Nagy N
Year: 2020
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Title: RET overactivation leads to concurrent Hirschsprung disease and intestinal ganglioneuromas.
Volume: 147
Issue: 21
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First Author: Huang EJ
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First Author: Ji B
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Title: Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies.
Volume: 28
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First Author: Yan H
Year: 2004
Journal: Dev Biol
Title: Neural cells in the esophagus respond to glial cell line-derived neurotrophic factor and neurturin, and are RET-dependent.
Volume: 272
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Pages: 118-33
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First Author: Hou G
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Ret is critical for podocyte survival following glomerular injury in vivo.
Volume: 308
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Journal: Proc Natl Acad Sci U S A
Title: Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease.
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Pages: 9345-50
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First Author: Gatto G
Year: 2013
Journal: J Neurosci
Title: Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and branching by repressing TrkB and Ret signaling.
Volume: 33
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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