|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1301 to 1388 out of 1388 for Itgb1

<< First    < Previous  |  Next >    Last >>
0.026s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
GXD Expression  
Probe: MGI:6197250
Assay Type: Immunohistochemistry
Annotation Date: 2018-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6197274
Age: embryonic day 11.5
Note: Co-localized with Itgb1 in neuroepithelial cells.
Specimen Label: S6
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7431095
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7431102
Age: postnatal adult
Image: 2C (right)
Note: Expression co-localized with Itgb1 in costamere at sarcolemmal membrane.
Specimen Label: 2C (right)
Detected: true
Specimen Num: 6
Allele
Name: integrin beta 1 (fibronectin receptor beta); endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 3, Reinhard Fassler
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 1.1, Elaine Fuchs
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Genotype
Symbol: Itgb1/Itgb1
Background: involves: 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 88  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 490  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 528  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
Protein Domain
Type: Family
Description: SCAI is a transcriptional cofactor and tumour suppressor that suppresses MKL1-induced SRF transcriptional activity. It may function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1 [].
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Genotype
Symbol: Itgb1/Itgb1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 606  
Fragment?: false
Protein Domain
Type: Family
Description: This entry represents protein SCAI from metazoans and plants. SCAI is a transcriptional cofactor and tumour suppressor that suppresses MKL1-induced SRF transcriptional activity. It may function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1 [].
Allele
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 5.1, Reinhard Fassler
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Itgb1/Itgb1
Background: involves: 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
Allele  
Name: integrin beta 3; targeted mutation 2, Ararat J Ablooglu
Allele Type: Targeted
Genotype
Symbol: Itgb1/Itgb1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Itgb3/Itgb3
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Itgb1/Itgb1 Tg(Ttr-cre)1Hadj/?
Background: involves: 129X1/SvJ * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false
Publication
First Author: Kimmel BE
Year: 1990
Journal: Genes Dev
Title: The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype.
Volume: 4
Issue: 5
Pages: 712-27
Publication  
First Author: Paço A
Year: 2020
Journal: Cancers (Basel)
Title: Roles of the HOX Proteins in Cancer Invasion and Metastasis.
Volume: 13
Issue: 1
Publication
First Author: Vogel M
Year: 2016
Journal: Am J Med Genet A
Title: Homozygous HOXB1 loss-of-function mutation in a large family with hereditary congenital facial paresis.
Volume: 170
Issue: 7
Pages: 1813-9
Publication    
First Author: Stefanovic S
Year: 2020
Journal: Elife
Title: Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation.
Volume: 9
Publication
First Author: Roux M
Year: 2015
Journal: Dev Biol
Title: Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development.
Volume: 406
Issue: 2
Pages: 247-58
Publication  
First Author: Roux M
Year: 2017
Journal: Mech Dev
Title: Hoxa1 and Hoxb1 are required for pharyngeal arch artery development.
Volume: 143
Pages: 1-8
Publication
First Author: Han L
Year: 2015
Journal: PLoS One
Title: HOXB1 Is a Tumor Suppressor Gene Regulated by miR-3175 in Glioma.
Volume: 10
Issue: 11
Pages: e0142387
Publication
First Author: Zaffran S
Year: 2018
Journal: Genesis
Title: Ectopic expression of Hoxb1 induces cardiac and craniofacial malformations.
Volume: 56
Issue: 6-7
Pages: e23221
Publication
First Author: Tischfield MA
Year: 2005
Journal: Nat Genet
Title: Homozygous HOXA1 mutations disrupt human brainstem, inner ear, cardiovascular and cognitive development.
Volume: 37
Issue: 10
Pages: 1035-7
Publication
First Author: Park H
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Homeobox D1 regulates angiogenic functions of endothelial cells via integrin β1 expression.
Volume: 408
Issue: 1
Pages: 186-92
Publication
First Author: Bosley TM
Year: 2008
Journal: Am J Med Genet A
Title: The clinical spectrum of homozygous HOXA1 mutations.
Volume: 146A
Issue: 10
Pages: 1235-40
Protein Domain
Type: Family
Description: This entry represents a group of homeobox proteins, including HOX-A1/B1/D1 (HXA1/B1/D1) and related proteins from animals. The homeobox domain is a DNA binding domain. Human HOX genes are critical for development of the central nervous system []. They have been also implicated in vascular development and angiogenesis, particularly with regulation of genes involved in cell-cell or cell-extracellular matrix (ECM) interactions []. HXA1 has been linked to the Bosley-Salih-Alorainy syndrome (BSAS) or the Athabascan brainstem dysgenesis syndrome (ABDS) []. HXB1 is a transcription factor that play important roles in early vertebrate development [, , , , ]and its expression is associated with tumours [, ]. HOXD1 plays a significant role in endothelial cell functions by regulating the expression of ITGB1 [].Homeobox protein rough from Drosophila melanogaster is a member of this group of proteins. It is required to establish the unique cell identity of photoreceptors R2 and R5 and consequently for ommatidial assembly in the developing eye imaginal disk in the organism [, ].
Publication
First Author: Chou J
Year: 2013
Journal: Nat Cell Biol
Title: GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.
Volume: 15
Issue: 2
Pages: 201-13
Publication
First Author: Brandt DT
Year: 2009
Journal: Nat Cell Biol
Title: SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.
Volume: 11
Issue: 5
Pages: 557-68
Publication
First Author: Ablooglu AJ
Year: 2009
Journal: Blood
Title: Antithrombotic effects of targeting alphaIIbbeta3 signaling in platelets.
Volume: 113
Issue: 15
Pages: 3585-92
Publication
First Author: Liao Z
Year: 2015
Journal: Blood
Title: Interaction of kindlin-2 with integrin β3 promotes outside-in signaling responses by the αVβ3 vitronectin receptor.
Volume: 125
Issue: 12
Pages: 1995-2004
Genotype
Symbol: Itgb1/Itgb1 Tg(KRT5-cre)5132Jlj/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Edil3/? Itgb1/Itgb1
Background: involves: 129X1/SvJ * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Sosa LJ
Year: 2013
Journal: PLoS One
Title: Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance.
Volume: 8
Issue: 5
Pages: e64521
Publication
First Author: Lu Q
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: SNRK (Sucrose Nonfermenting 1-Related Kinase) Promotes Angiogenesis In Vivo.
Volume: 38
Issue: 2
Pages: 373-385
Publication
First Author: Sun Y
Year: 2022
Journal: Theranostics
Title: Ninj2 regulates Schwann cells development by interfering laminin-integrin signaling.
Volume: 12
Issue: 17
Pages: 7307-7318
Publication
First Author: Tajiri Y
Year: 2010
Journal: Biol Reprod
Title: Tubulointerstitial nephritis antigen-like 1 is expressed in the uterus and binds with integrins in decidualized endometrium during postimplantation in mice.
Volume: 82
Issue: 2
Pages: 263-70
Publication
First Author: Wagner JUG
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.
Volume: 38
Issue: 5
Pages: 1170-1177
Publication  
First Author: Riffo E
Year: 2022
Journal: Front Cell Dev Biol
Title: The Sall2 transcription factor promotes cell migration regulating focal adhesion turnover and integrin β1 expression.
Volume: 10
Pages: 1031262
Publication
First Author: Sevilla-Movilla S
Year: 2020
Journal: J Pathol
Title: Upregulated expression and function of the α4β1 integrin in multiple myeloma cells resistant to bortezomib.
Volume: 252
Issue: 1
Pages: 29-40
Protein
Organism: Mus musculus/domesticus
Length: 27  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 328  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 337  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: false