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Search results 1301 to 1400 out of 1663 for Mef2c

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Type Details Score
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
29431698 | J:260708
First Author: Brown FC
Year: 2018
Journal: Cancer Discov
Title: MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia.
Volume: 8
Issue: 4
Pages: 478-497
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Publication
38848814 | J:359477
First Author: Ward C
Year: 2024
Journal: Biol Psychiatry
Title: Developmental Disruption of Mef2c in Medial Ganglionic Eminence-Derived Cortical Inhibitory Interneurons Impairs Cellular and Circuit Function.
Volume: 96
Issue: 10
Pages: 804-814
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Publication
33540048 | J:307770
 
First Author: Xue F
Year: 2021
Journal: Neurobiol Dis
Title: Type I interferon response-related microglial Mef2c deregulation at the onset of Alzheimer's pathology in 5×FAD mice.
Volume: 152
Pages: 105272
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Allele
Mef2c<tm1Eno> | MGI:1857491
Name: myocyte enhancer factor 2C; targeted mutation 1, Eric N Olson
Allele Type: Targeted
Attribute String: Null/knockout
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Regulatory Region
MGI:7447332 | Rr399
Type: enhancer
Organism: mouse, laboratory
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Interaction Experiment
Badodi S (2015)
Description: Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition.
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Publication
28361052 | J:310588
 
First Author: Amara CS
Year: 2017
Journal: Front Cell Dev Biol
Title: CaMKII Signaling Stimulates Mef2c Activity In Vitro but Only Minimally Affects Murine Long Bone Development in vivo.
Volume: 5
Pages: 20
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Publication
23174904 | J:199063
First Author: Agatheeswaran S
Year: 2013
Journal: Leukemia
Title: BCR-ABL mediated repression of miR-223 results in the activation of MEF2C and PTBP2 in chronic myeloid leukemia.
Volume: 27
Issue: 7
Pages: 1578-80
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Transgene
MGI:3851581 | Tg(Myh6-Mef2c)2Jmol
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4356547 | Tg(Mef2c-lacZ)5Blk
Type: transgene
Organism: mouse, laboratory
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Interaction Experiment
Vincentz JW (2008)
Description: Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development.
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Publication
26101156 | J:229430
First Author: Yuasa K
Year: 2015
Journal: Exp Cell Res
Title: JAZF1 promotes proliferation of C2C12 cells, but retards their myogenic differentiation through transcriptional repression of MEF2C and MRF4-Implications for the role of Jazf1 variants in oncogenesis and type 2 diabetes.
Volume: 336
Issue: 2
Pages: 287-97
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Publication
25789873 | -
First Author: Badodi S
Year: 2015
Journal: Cell Cycle
Title: Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition.
Volume: 14
Issue: 10
Pages: 1517-28
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Publication
8663403 | -
First Author: Molkentin JD
Year: 1996
Journal: J Biol Chem
Title: Phosphorylation of the MADS-Box transcription factor MEF2C enhances its DNA binding activity.
Volume: 271
Issue: 29
Pages: 17199-204
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Allele
Tg(Myog-cre)1Eno | MGI:3530558
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
34555201 | J:317718
First Author: Morales PE
Year: 2021
Journal: FASEB J
Title: Skeletal muscle type-specific mitochondrial adaptation to high-fat diet relies on differential autophagy modulation.
Volume: 35
Issue: 10
Pages: e21933
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Publication
37917630 | J:342903
First Author: Jia B
Year: 2023
Journal: PLoS One
Title: Exercise performance is not improved in mice with skeletal muscle deletion of natriuretic peptide clearance receptor.
Volume: 18
Issue: 11
Pages: e0293636
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Publication
16024798 | J:100019
First Author: Oh M
Year: 2005
Journal: Mol Cell Biol
Title: Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.
Volume: 25
Issue: 15
Pages: 6629-38
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Strain
MGI:3851813 | FVB-Tg(Myh6-Mef2c)2Jmol/J
Attribute String: transgenic, mutant strain, coisogenic
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Allele
Tg(Myog-Myhas)#Bcgen | MGI:7545567
Name: transgene insertion, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Myh6-Mef2c)2Jmol/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
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DO Term
DOID:0070050 | neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language
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Publication
33586679 | J:333685
 
First Author: Fan L
Year: 2021
Journal: J Clin Invest
Title: Muscle Krüppel-like factor 15 regulates lipid flux and systemic metabolic homeostasis.
Volume: 131
Issue: 4
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Allele
Tg(Myh6-Mef2c/VP16)1Eno | MGI:4418154
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Mef2c<tm1Smoc> | MGI:7291020
Name: myocyte enhancer factor 2C; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:7545579 | C57BL/6J-Tg(Myog-Myhas)#Bcgen
Attribute String: coisogenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Mef2d/Mef2d Tg(Myog-cre)1Eno/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Myog-Myhas)#Bcgen/?
Background: C57BL/6J-Tg(Myog-Myhas)#Bcgen
Zygosity: ot
Has Mutant Allele: true
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Publication
38467649 | J:360919
First Author: Gilbert CJ
Year: 2024
Journal: Nat Commun
Title: YTHDF2 governs muscle size through a targeted modulation of proteostasis.
Volume: 15
Issue: 1
Pages: 2176
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Allele
Tg(Col2a1-Mef2c/VP16)1Eno | MGI:3719002
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Mef2c-lacZ)4Blk | MGI:4356543
Name: transgene insertion 4, Brian L Black
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Mef2c<tm1.1Wtp> | MGI:5606040
Name: myocyte enhancer factor 2C; targeted mutation 1.1, William T Pu
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Mapk11/Mapk11 Tg(Myog-cre)1Eno/?
Background: involves: 129S/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mapk12/Mapk12 Tg(Myog-cre)1Eno/?
Background: involves: 129S/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Myh6-Mef2c/VP16)1Eno/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pnpla2/Pnpla2 Tg(Myog-cre)1Eno/?
Background: involves: 129S * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
16469744 | J:111573
First Author: Xu J
Year: 2006
Journal: J Biol Chem
Title: Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice.
Volume: 281
Issue: 14
Pages: 9152-62
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HT Experiment
GSE226381 | Cyclic GMP-AMP synthase and interferon activation diminish MEF2C-mediated cognitive resilience II
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
24367119 | J:206378
First Author: Singh S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration.
Volume: 111
Issue: 1
Pages: E129-38
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Publication
26883362 | J:229530
First Author: Amoasii L
Year: 2016
Journal: Genes Dev
Title: A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism.
Volume: 30
Issue: 4
Pages: 434-46
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Publication
17717603 | J:127419
First Author: Kitamura T
Year: 2007
Journal: J Clin Invest
Title: A Foxo/Notch pathway controls myogenic differentiation and fiber type specification.
Volume: 117
Issue: 9
Pages: 2477-85
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Publication
32414934 | J:343900
First Author: Kim J
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility.
Volume: 117
Issue: 22
Pages: 12435-12443
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Publication
20088826 | J:161014
First Author: Yamazaki Y
Year: 2010
Journal: Biochem J
Title: The cathepsin L gene is a direct target of FOXO1 in skeletal muscle.
Volume: 427
Issue: 1
Pages: 171-8
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Publication
29477142 | J:280590
First Author: Pigna E
Year: 2018
Journal: Skelet Muscle
Title: HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses.
Volume: 8
Issue: 1
Pages: 6
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Publication
30319457 | J:276793
 
First Author: Renzini A
Year: 2018
Journal: Front Physiol
Title: HDAC4 Regulates Skeletal Muscle Regeneration via Soluble Factors.
Volume: 9
Pages: 1387
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Publication
25074987 | J:215781
First Author: Kamei Y
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: FOXO1 activates glutamine synthetase gene in mouse skeletal muscles through a region downstream of 3'-UTR: possible contribution to ammonia detoxification.
Volume: 307
Issue: 6
Pages: E485-93
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Allele
Tg(Mef2c-cre)2Blk | MGI:3639735
Name: transgene insertion 2, Brian L Black
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Col2a1-Mef2c/en)1Eno | MGI:3718996
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Dominant negative, Inserted expressed sequence
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Allele
Tg(Mef2c-lacZ)3Blk | MGI:4356494
Name: transgene insertion 3, Brian L Black
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Mef2c-lacZ)6Blk | MGI:4357694
Name: transgene insertion 6, Brian L Black
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Mef2c-EGFP)GJ92Gsat | MGI:4847229
Name: transgene insertion GJ92, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Mef2c-dre/ERT2)#Bbr | MGI:6790590
Name: transgene insertion, Benoit G Bruneau
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Tg(Rr399-lacZ)#Blk | MGI:7447333
Name: transgene insertion, Brian L Black
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Tg(Col2a1-Mef2c/VP16)1Eno/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mapk14/Mapk14 Tg(Myog-cre)1Eno/?
Background: involves: 129S5/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hdac4/Hdac4 Tg(Myog-cre)1Eno/?
Background: involves: 129S/SvEv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cygb/Cygb Tg(Myog-cre)1Eno/?
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mef2c/Mef2c
Background: involves: 129S4/SvJae * C57BL/6 * SJL * Swiss Webster
Zygosity: hm
Has Mutant Allele: true
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Publication
17519332 | J:143626
First Author: Ai D
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Canonical Wnt signaling functions in second heart field to promote right ventricular growth.
Volume: 104
Issue: 22
Pages: 9319-24
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Publication
17803194 | J:152135
First Author: Axton R
Year: 2008
Journal: J Cell Biochem
Title: Aminopeptidase O contains a functional nucleolar localization signal and is implicated in vascular biology.
Volume: 103
Issue: 4
Pages: 1171-82
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Protein
Q80VC3
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: false
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Protein
A0A1Y7VJX1
Organism: Mus musculus/domesticus
Length: 69  
Fragment?: true
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Protein Domain
IPR033577 | AOPep
Type: Family
Description: Aminopeptidase O (MEROPS identifier M01.028) is an intracellular aminopeptidase. There is a nucleolar location signal located between the peptidase and ARM-repeat domains. Aminopeptidase O has been localized to the nucleolus, and in the mouse a shorter isoform, generated by alternative initiation, is found in adult and embryonic blood vessels, mainly in the endothelial and smooth muscle cells []. The AOPEP gene also includes a cluster of microRNAs, one of which modulates expression of the Mef2c gene which encodes myocyte-specific enhancer factor 2C []. It is possible that aminopeptidase O is involved in development of vasculature in the embryo and control of blood pressure.
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Publication
28663257 | J:269269
First Author: Sawada H
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Smooth Muscle Cells Derived From Second Heart Field and Cardiac Neural Crest Reside in Spatially Distinct Domains in the Media of the Ascending Aorta-Brief Report.
Volume: 37
Issue: 9
Pages: 1722-1726
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Publication
19936205 | J:155408
First Author: Pogozelski AR
Year: 2009
Journal: PLoS One
Title: p38gamma mitogen-activated protein kinase is a key regulator in skeletal muscle metabolic adaptation in mice.
Volume: 4
Issue: 11
Pages: e7934
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Publication
26556890 | J:237670
First Author: D'Cruz R
Year: 2016
Journal: Biochem J
Title: PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle.
Volume: 473
Issue: 3
Pages: 267-76
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Publication
23110050 | J:192160
First Author: Nagpal P
Year: 2012
Journal: PLoS One
Title: The ubiquitin ligase Nedd4-1 participates in denervation-induced skeletal muscle atrophy in mice.
Volume: 7
Issue: 10
Pages: e46427
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Publication
20032509 | J:157663
First Author: Geng T
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: PGC-1alpha plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle.
Volume: 298
Issue: 3
Pages: C572-9
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Publication
28028037 | J:244203
First Author: Gudiksen A
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Muscle interleukin-6 and fasting-induced PDH regulation in mouse skeletal muscle.
Volume: 312
Issue: 3
Pages: E204-E214
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Publication
26109166 | J:254168
First Author: Knudsen JG
Year: 2015
Journal: Obesity (Silver Spring)
Title: Skeletal muscle interleukin-6 regulates metabolic factors in iWAT during HFD and exercise training.
Volume: 23
Issue: 8
Pages: 1616-24
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Publication
17702743 | J:126742
First Author: Handschin C
Year: 2007
Journal: J Biol Chem
Title: Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals.
Volume: 282
Issue: 41
Pages: 30014-21
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Publication
28356270 | J:243307
First Author: Call JA
Year: 2017
Journal: Am J Physiol Cell Physiol
Title: Ulk1-mediated autophagy plays an essential role in mitochondrial remodeling and functional regeneration of skeletal muscle.
Volume: 312
Issue: 6
Pages: C724-C732
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Publication
31290266 | J:297012
First Author: Gill JF
Year: 2019
Journal: Aging Cell
Title: Peroxisome proliferator-activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging.
Volume: 18
Issue: 5
Pages: e12993
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Publication
28223292 | J:244935
First Author: Schnyder S
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Muscle PGC-1α is required for long-term systemic and local adaptations to a ketogenic diet in mice.
Volume: 312
Issue: 5
Pages: E437-E446
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Publication
22482732 | J:184457
First Author: Blättler SM
Year: 2012
Journal: Cell Metab
Title: Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.
Volume: 15
Issue: 4
Pages: 505-17
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Publication
22711985 | J:186715
First Author: Blättler SM
Year: 2012
Journal: Mol Cell Biol
Title: Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle.
Volume: 32
Issue: 16
Pages: 3333-46
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Publication
26748706 | J:269824
First Author: Davies MN
Year: 2016
Journal: Cell Rep
Title: The Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-Induced Lysine Acetylation of Mitochondrial Proteins.
Volume: 14
Issue: 2
Pages: 243-54
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Publication
27327080 | J:248737
First Author: Gudiksen A
Year: 2016
Journal: PLoS One
Title: Lack of Skeletal Muscle IL-6 Affects Pyruvate Dehydrogenase Activity at Rest and during Prolonged Exercise.
Volume: 11
Issue: 6
Pages: e0156460
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Publication
22645307 | J:186645
First Author: Li T
Year: 2012
Journal: Mol Cell Biol
Title: STIM1-Ca(2+) signaling is required for the hypertrophic growth of skeletal muscle in mice.
Volume: 32
Issue: 15
Pages: 3009-17
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