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Search results 1301 to 1400 out of 4141 for Mtor

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Type Details Score
Publication
20071534 | J:157708
First Author: Sharma A
Year: 2010
Journal: J Neurosci
Title: Dysregulation of mTOR signaling in fragile X syndrome.
Volume: 30
Issue: 2
Pages: 694-702
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Protein
Q9CQ22
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: false
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Publication
30910408 | J:277302
 
First Author: Pita-Thomas W
Year: 2019
Journal: Exp Neurol
Title: HDAC5 promotes optic nerve regeneration by activating the mTOR pathway.
Volume: 317
Pages: 271-283
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Publication
19177150 | J:168293
First Author: Nada S
Year: 2009
Journal: EMBO J
Title: The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.
Volume: 28
Issue: 5
Pages: 477-89
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Publication
15545625 | -
First Author: Brugarolas J
Year: 2004
Journal: Genes Dev
Title: Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex.
Volume: 18
Issue: 23
Pages: 2893-904
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Publication
24469052 | J:218632
First Author: Akeno N
Year: 2015
Journal: Oncogene
Title: p53 suppresses carcinoma progression by inhibiting mTOR pathway activation.
Volume: 34
Issue: 5
Pages: 589-99
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Publication
19225151 | J:314078
First Author: Jung CH
Year: 2009
Journal: Mol Biol Cell
Title: ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.
Volume: 20
Issue: 7
Pages: 1992-2003
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Publication
18391955 | J:134510
First Author: Sinclair LV
Year: 2008
Journal: Nat Immunol
Title: Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking.
Volume: 9
Issue: 5
Pages: 513-21
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Publication
29133930 | J:256303
First Author: Yu M
Year: 2017
Journal: Nat Commun
Title: PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.
Volume: 8
Issue: 1
Pages: 1457
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Publication
34031390 | J:307283
First Author: Ma N
Year: 2021
Journal: Nat Commun
Title: PPDPF alleviates hepatic steatosis through inhibition of mTOR signaling.
Volume: 12
Issue: 1
Pages: 3059
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Publication
21284988 | J:169560
First Author: Kim S
Year: 2011
Journal: Cell Metab
Title: Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase.
Volume: 13
Issue: 2
Pages: 215-21
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Publication
26279396 | J:229176
 
First Author: Xu G
Year: 2015
Journal: Mol Cell Endocrinol
Title: Ghrelin regulates GLP-1 production through mTOR signaling in L cells.
Volume: 416
Pages: 9-18
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Publication
26280535 | J:227355
First Author: Herranz N
Year: 2015
Journal: Nat Cell Biol
Title: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Volume: 17
Issue: 9
Pages: 1205-17
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Publication
35836818 | J:326786
First Author: Liu JT
Year: 2022
Journal: Theranostics
Title: Arterial cyclic stretch regulates Lamtor1 and promotes neointimal hyperplasia via circSlc8a1/miR-20a-5p axis in vein grafts.
Volume: 12
Issue: 11
Pages: 4851-4865
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Publication
28878358 | J:253000
First Author: Zhang YK
Year: 2017
Journal: Nat Commun
Title: Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.
Volume: 8
Issue: 1
Pages: 464
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Publication
39374769 | J:355629
 
First Author: Tsai CW
Year: 2024
Journal: Neuropharmacology
Title: Abnormal increased mTOR signaling regulates seizure threshold in Dravet syndrome.
Volume: 262
Pages: 110166
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Publication
23081885 | J:217855
First Author: Tsai V
Year: 2014
Journal: Cereb Cortex
Title: Fetal brain mTOR signaling activation in tuberous sclerosis complex.
Volume: 24
Issue: 2
Pages: 315-27
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Publication
25735853 | J:253710
First Author: Gentilella A
Year: 2015
Journal: Biochim Biophys Acta
Title: A liaison between mTOR signaling, ribosome biogenesis and cancer.
Volume: 1849
Issue: 7
Pages: 812-20
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Publication
37138032 | J:337525
First Author: Leibowitz BJ
Year: 2023
Journal: Oncogene
Title: mTOR inhibition suppresses Myc-driven polyposis by inducing immunogenic cell death.
Volume: 42
Issue: 24
Pages: 2007-2016
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Publication
30268766 | J:269377
 
First Author: Arafa SR
Year: 2019
Journal: Exp Neurol
Title: Self-reinforcing effects of mTOR hyperactive neurons on dendritic growth.
Volume: 311
Pages: 125-134
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Publication
24124460 | J:209026
First Author: Sun ZJ
Year: 2013
Journal: PLoS One
Title: Inhibition of mTOR reduces anal carcinogenesis in transgenic mouse model.
Volume: 8
Issue: 10
Pages: e74888
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Publication
23593290 | J:200028
First Author: Deming DA
Year: 2013
Journal: PLoS One
Title: mTOR inhibition elicits a dramatic response in PI3K-dependent colon cancers.
Volume: 8
Issue: 4
Pages: e60709
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Protein
A0A0A6YX02
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: false
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Publication
22427693 | J:197811
First Author: Taub N
Year: 2012
Journal: J Cell Sci
Title: The late endosomal adaptor p14 is a macrophage host-defense factor against Salmonella infection.
Volume: 125
Issue: Pt 11
Pages: 2698-708
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Publication
34728526 | J:341281
First Author: Wang Y
Year: 2022
Journal: Clin Cancer Res
Title: Cholesterol-Lowering Intervention Decreases mTOR Complex 2 Signaling and Enhances Antitumor Immunity.
Volume: 28
Issue: 2
Pages: 414-424
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Gene
100361543 | Lamtor1l1
Type: gene
Organism: rat
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Gene
100360584 | Lamtor2-ps2
Type: gene
Organism: rat
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Gene
120096722 | Lamtor2-ps1
Type: gene
Organism: rat
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Gene
108703515 | lamtor4.S
Type: gene
Organism: frog, African clawed
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Gene
108706168 | lamtor1.L
Type: gene
Organism: frog, African clawed
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Gene
379557 | lamtor3.L
Type: gene
Organism: frog, African clawed
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Gene
379741 | lamtor2.S
Type: gene
Organism: frog, African clawed
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Gene
379890 | lamtor1.S
Type: gene
Organism: frog, African clawed
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Gene
380570 | lamtor3l.L
Type: gene
Organism: frog, African clawed
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Gene
432061 | lamtor5.S
Type: gene
Organism: frog, African clawed
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Gene
494825 | lamtor2.L
Type: gene
Organism: frog, African clawed
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Publication
22958934 | J:193428
First Author: Kalaitzidis D
Year: 2012
Journal: Cell Stem Cell
Title: mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.
Volume: 11
Issue: 3
Pages: 429-39
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Strain
MGI:3641471 | B6;129S4-Mtor<tm1Yam>
Attribute String: mutant stock, targeted mutation
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Strain
MGI:3641532 | B6;129S4-Mtor<tm2Yam>
Attribute String: targeted mutation, mutant stock
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Interaction Experiment
Cunningham JT (2007)
Description: mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
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Publication
32128508 | J:345483
First Author: Zhang X
Year: 2020
Journal: Nat Metab
Title: High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy.
Volume: 2
Issue: 1
Pages: 110-125
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Publication
21816276 | J:174681
First Author: Peterson TR
Year: 2011
Journal: Cell
Title: mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.
Volume: 146
Issue: 3
Pages: 408-20
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Publication
26833095 | J:254440
 
First Author: Wu T
Year: 2016
Journal: Sci Rep
Title: mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors.
Volume: 6
Pages: 20250
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Publication
24092934 | J:206480
First Author: Sparber F
Year: 2014
Journal: Blood
Title: The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis.
Volume: 123
Issue: 2
Pages: 217-27
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Protein
O88653
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: false
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Publication
25078666 | J:216190
First Author: Sparber F
Year: 2015
Journal: J Invest Dermatol
Title: The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells.
Volume: 135
Issue: 1
Pages: 119-129
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Protein Coding Gene
MGI:3781768 | Lamtor3l
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25623400 | J:318267
First Author: Steiner JL
Year: 2015
Journal: Alcohol Clin Exp Res
Title: Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction.
Volume: 39
Issue: 1
Pages: 1-10
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Publication
23223022 | J:208593
First Author: Wang Y
Year: 2013
Journal: Diabetes
Title: MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic β-cells.
Volume: 62
Issue: 3
Pages: 887-95
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Publication
31865844 | J:313587
First Author: Bork T
Year: 2020
Journal: Autophagy
Title: Podocytes maintain high basal levels of autophagy independent of mtor signaling.
Volume: 16
Issue: 11
Pages: 1932-1948
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Publication
29686050 | J:263174
First Author: Hayama Y
Year: 2018
Journal: J Immunol
Title: Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB.
Volume: 200
Issue: 11
Pages: 3790-3800
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Protein
Q8BSK8
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Publication
7809080 | -
First Author: Chiu MI
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex.
Volume: 91
Issue: 26
Pages: 12574-8
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Publication
11930000 | -
First Author: Desai BN
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction.
Volume: 99
Issue: 7
Pages: 4319-24
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Publication
21659604 | -
First Author: Hsu PP
Year: 2011
Journal: Science
Title: The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.
Volume: 332
Issue: 6035
Pages: 1317-22
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Publication
18692468 | J:139563
First Author: Budanov AV
Year: 2008
Journal: Cell
Title: p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling.
Volume: 134
Issue: 3
Pages: 451-60
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Publication
21145759 | J:167293
First Author: Procaccini C
Year: 2010
Journal: Immunity
Title: An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.
Volume: 33
Issue: 6
Pages: 929-41
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Publication
18757421 | J:138927
First Author: Squarize CH
Year: 2008
Journal: Cancer Res
Title: Chemoprevention and treatment of experimental Cowden's disease by mTOR inhibition with rapamycin.
Volume: 68
Issue: 17
Pages: 7066-72
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Publication
30445039 | J:268003
First Author: Brandt C
Year: 2018
Journal: Cell
Title: Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation.
Volume: 175
Issue: 5
Pages: 1321-1335.e20
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Publication
22424772 | J:188028
First Author: Huot MÉ
Year: 2012
Journal: Mol Cell
Title: The Sam68 STAR RNA-binding protein regulates mTOR alternative splicing during adipogenesis.
Volume: 46
Issue: 2
Pages: 187-99
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Publication
30146486 | J:269409
First Author: Bruning U
Year: 2018
Journal: Cell Metab
Title: Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.
Volume: 28
Issue: 6
Pages: 866-880.e15
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Publication
32034158 | J:286716
First Author: Viscarra JA
Year: 2020
Journal: Nat Commun
Title: Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis.
Volume: 11
Issue: 1
Pages: 796
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Publication
31978189 | J:284067
First Author: Yang F
Year: 2020
Journal: PLoS One
Title: Epilepsy in a melanocyte-lineage mTOR hyperactivation mouse model: A novel epilepsy model.
Volume: 15
Issue: 1
Pages: e0228204
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Publication
29317619 | J:258245
First Author: Chen X
Year: 2018
Journal: Nat Commun
Title: Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway.
Volume: 9
Issue: 1
Pages: 114
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Publication
25257176 | J:260872
First Author: Morquette B
Year: 2015
Journal: Cell Death Differ
Title: REDD2-mediated inhibition of mTOR promotes dendrite retraction induced by axonal injury.
Volume: 22
Issue: 4
Pages: 612-25
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Publication
31325484 | J:285589
 
First Author: Blomberg R
Year: 2019
Journal: Matrix Biol
Title: Fibroblast activation protein restrains adipogenic differentiation and regulates matrix-mediated mTOR signaling.
Volume: 83
Pages: 60-76
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Publication
30258985 | J:288873
First Author: Harwood FC
Year: 2018
Journal: Sci Adv
Title: ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer.
Volume: 4
Issue: 9
Pages: eaar3938
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Publication
22399812 | J:197817
First Author: Lamouille S
Year: 2012
Journal: J Cell Sci
Title: TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion.
Volume: 125
Issue: Pt 5
Pages: 1259-73
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Publication
37738689 | J:344268
First Author: Guo R
Year: 2023
Journal: Int Immunopharmacol
Title: Depletion of mTOR ameliorates CD(4)(+) T cell pyroptosis by promoting autophagy activity in septic mice.
Volume: 124
Issue: Pt B
Pages: 110964
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Protein
Q9D1L9
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: false
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Publication
22771762 | J:192397
First Author: Camacho A
Year: 2012
Journal: Exp Neurol
Title: Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response.
Volume: 237
Issue: 2
Pages: 396-406
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Publication
19246562 | J:149377
First Author: Cullion K
Year: 2009
Journal: Blood
Title: Targeting the Notch1 and mTOR pathways in a mouse T-ALL model.
Volume: 113
Issue: 24
Pages: 6172-81
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Publication
25315683 | J:243817
 
First Author: McMahon JJ
Year: 2015
Journal: Neurobiol Dis
Title: Seizure-dependent mTOR activation in 5-HT neurons promotes autism-like behaviors in mice.
Volume: 73
Pages: 296-306
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Publication
23766271 | J:204017
First Author: Sun H
Year: 2013
Journal: Stem Cells
Title: Osteoblast-targeted suppression of PPARγ increases osteogenesis through activation of mTOR signaling.
Volume: 31
Issue: 10
Pages: 2183-92
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Publication
24574514 | J:210527
First Author: Wang Y
Year: 2014
Journal: Cancer Res
Title: Foxp3+ T cells inhibit antitumor immune memory modulated by mTOR inhibition.
Volume: 74
Issue: 8
Pages: 2217-28
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Publication
31469601 | J:299171
First Author: Xu X
Year: 2019
Journal: FASEB J
Title: Enhanced mTOR complex 1 signaling attenuates diabetic cardiac injury in OVE26 mice.
Volume: 33
Issue: 11
Pages: 12800-12811
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Publication
37437211 | J:343200
First Author: Levitin MO
Year: 2023
Journal: Brain
Title: Models of KPTN-related disorder implicate mTOR signalling in cognitive and overgrowth phenotypes.
Volume: 146
Issue: 11
Pages: 4766-4783
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Publication
19451232 | J:150143
First Author: Lee MN
Year: 2009
Journal: Mol Cell Biol
Title: Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb.
Volume: 29
Issue: 14
Pages: 3991-4001
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Publication
28192515 | J:252022
First Author: Ganesan R
Year: 2017
Journal: PLoS Pathog
Title: Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy.
Volume: 13
Issue: 2
Pages: e1006227
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Publication
21576258 | J:305415
First Author: Dai N
Year: 2011
Journal: Genes Dev
Title: mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry.
Volume: 25
Issue: 11
Pages: 1159-72
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Publication
31607856 | J:310135
 
First Author: Kadoya M
Year: 2019
Journal: Front Neurosci
Title: Negative Regulation of mTOR Signaling Restricts Cell Proliferation in the Floor Plate.
Volume: 13
Pages: 1022
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Publication
36385525 | J:339984
First Author: Schmitt M
Year: 2022
Journal: Nature
Title: Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulation.
Volume: 612
Issue: 7939
Pages: 347-353
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Publication
37846480 | J:343275
First Author: Turgu B
Year: 2023
Journal: EMBO Rep
Title: The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes.
Volume: 24
Issue: 12
Pages: e56815
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Publication
30509128 | J:287992
First Author: You JS
Year: 2019
Journal: FASEB J
Title: The role of raptor in the mechanical load-induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy.
Volume: 33
Issue: 3
Pages: 4021-4034
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Publication
25752454 | J:241973
First Author: Nguyen LH
Year: 2015
Journal: Epilepsia
Title: mTOR inhibition suppresses established epilepsy in a mouse model of cortical dysplasia.
Volume: 56
Issue: 4
Pages: 636-46
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Publication
19209957 | J:245261
First Author: Feldman ME
Year: 2009
Journal: PLoS Biol
Title: Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
Volume: 7
Issue: 2
Pages: e38
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Publication
36451866 | J:331710
First Author: Luo YD
Year: 2022
Journal: Theranostics
Title: Mutant Kras and mTOR crosstalk drives hepatocellular carcinoma development via PEG3/STAT3/BEX2 signaling.
Volume: 12
Issue: 18
Pages: 7903-7919
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Publication
37012862 | J:334737
 
First Author: Sun Y
Year: 2023
Journal: Int Immunopharmacol
Title: Reduction of peritoneal cavity B1a cells in adult Slc7a5 knockdown mice via dysregulating the mTOR pathway.
Volume: 117
Pages: 109939
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Publication
11504907 | J:71306
First Author: Podsypanina K
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice.
Volume: 98
Issue: 18
Pages: 10320-5
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Allele
Meak7<+> | MGI:5469962
 
Name: MTOR associated protein, eak-7 homolog; wild type
Allele Type: Not Specified
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Publication
28768723 | J:250953
First Author: Hosokawa T
Year: 2017
Journal: J Immunol
Title: Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function.
Volume: 199
Issue: 6
Pages: 2008-2019
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Publication
25887293 | J:230338
 
First Author: Ma S
Year: 2015
Journal: Exp Eye Res
Title: Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival.
Volume: 135
Pages: 1-13
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Publication
36627370 | J:332498
First Author: Tran Nguyen Truc L
Year: 2023
Journal: Sci Rep
Title: Mechanism of cystogenesis by Cd79a-driven, conditional mTOR activation in developing mouse nephrons.
Volume: 13
Issue: 1
Pages: 508
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Protein Coding Gene
MGI:1270849 | Rps6kb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1195261 | Eef2k
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O08796
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
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Pathway
R-MMU-380972 | Energy dependent regulation of mTOR by LKB1-AMPK
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Publication
31203721 | J:339827
First Author: Wu YF
Year: 2020
Journal: Autophagy
Title: Inactivation of MTOR promotes autophagy-mediated epithelial injury in particulate matter-induced airway inflammation.
Volume: 16
Issue: 3
Pages: 435-450
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HT Experiment
GSE89762 | The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
29259128 | J:258406
First Author: Li H
Year: 2018
Journal: J Biol Chem
Title: Hepatitis B X-interacting protein promotes the formation of the insulin gene-transcribing protein complex Pdx-1/Neurod1 in animal pancreatic β-cells.
Volume: 293
Issue: 6
Pages: 2053-2065
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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