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Search results 1301 to 1400 out of 1400 for Plp1

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Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Tg(Plp)72Kan/Tg(Plp)72Kan
Background: B6N.Cg-Tg(Plp)72Kan
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:3210 | Pelizaeus-Merzbacher disease
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Allele
Plp1<tm3Wst> | MGI:3617313
Name: proteolipid protein (myelin) 1; targeted mutation 3, Wilhelm Stoffel
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:6281717 | B6;CBA-Tg(Plp1-EGFP)10Wmac/J
Attribute String: transgenic, mutant stock
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Publication
11826117 | J:211768
First Author: Mallon BS
Year: 2002
Journal: J Neurosci
Title: Proteolipid promoter activity distinguishes two populations of NG2-positive cells throughout neonatal cortical development.
Volume: 22
Issue: 3
Pages: 876-85
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Publication
31029597 | J:278122
 
First Author: Liu Y
Year: 2019
Journal: Exp Neurol
Title: Concentration-dependent effects of CSF1R inhibitors on oligodendrocyte progenitor cells ex vivo and in vivo.
Volume: 318
Pages: 32-41
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Publication
30904666 | J:352905
 
First Author: Berardino BG
Year: 2019
Journal: Neuroscience
Title: Exposure to enriched environment rescues anxiety-like behavior and miRNA deregulated expression induced by perinatal malnutrition while altering oligodendrocyte morphology.
Volume: 408
Pages: 115-134
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Publication
28559442 | J:265108
First Author: Negro S
Year: 2017
Journal: EMBO Mol Med
Title: CXCL12α/SDF-1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals.
Volume: 9
Issue: 8
Pages: 1000-1010
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Publication
28931809 | J:254895
First Author: Ryan DP
Year: 2017
Journal: Nat Commun
Title: Automatic and adaptive heterogeneous refractive index compensation for light-sheet microscopy.
Volume: 8
Issue: 1
Pages: 612
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Publication
18512250 | J:156265
First Author: Pedraza CE
Year: 2008
Journal: Glia
Title: Production, characterization, and efficient transfection of highly pure oligodendrocyte precursor cultures from mouse embryonic neural progenitors.
Volume: 56
Issue: 12
Pages: 1339-52
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Allele
Plp1<em1Smoc> | MGI:7291721
Name: proteolipid protein (myelin) 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Tg(Plp1-EGFP)10Wmac/?
Background: involves: C57BL/6 * CBA * FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Plp1-EGFP)10Wmac/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Strain
MGI:3620232 | B6.129S1-Plp1<tm3Wst>
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Plp1/Plp1
Background: B6.129S1-Plp1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Plp1/Plp1<+>
Background: B6.129S1-Plp1
Zygosity: ht
Has Mutant Allele: true
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Publication
16630588 | J:110442
First Author: Morris JK
Year: 2006
Journal: Brain Res
Title: A disorganized innervation of the inner ear persists in the absence of ErbB2.
Volume: 1091
Issue: 1
Pages: 186-99
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Allele
Tg(Plp1-HTT*150Q)4aXjl | MGI:5700344
Name: transgene insertion 4a, Xiao-Jiang Li
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
32154930 | J:296448
First Author: Chalazonitis A
Year: 2020
Journal: J Comp Neurol
Title: Cerebral dopamine neurotrophic factor is essential for enteric neuronal development, maintenance, and regulation of gastrointestinal transit.
Volume: 528
Issue: 14
Pages: 2420-2444
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Strain
MGI:6771062 | C57BL/6JSmoc-Plp1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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HT Experiment
GSE72560 | Enteric glia express proteolipid protein 1 and are a transcriptionally unique population of glia in the mammalian nervous system
Series Id: E-GEOD-72560
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Strain
MGI:3828439 | B6.129-Plp1<tm1Frca>
Attribute String: targeted mutation, congenic
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Allele
Tg(PLP1*)4Rsj | MGI:4459455
Name: transgene insertion 4, Ravina Simons Johnson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Plp1-cre)F633Rako | MGI:5297401
Name: transgene insertion F633, Rashmi Kothary
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Plp1-cre)F627Rako | MGI:5297408
Name: transgene insertion F627, Rashmi Kothary
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
25789755 | J:221608
First Author: Huang B
Year: 2015
Journal: Neuron
Title: Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes.
Volume: 85
Issue: 6
Pages: 1212-26
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Allele
Hprt1<tm1(Hsp-PLP1)Apt> | MGI:7496015
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Alan Peterson
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Hprt1<tm2(Hsp-PLP1*L30R)Apt> | MGI:7496019
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, Alan Peterson
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Hprt1<tm3(Hsp-PLP1*R137W)Apt> | MGI:7496020
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 3, Alan Peterson
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Plp1-HTT*150Q)4aXjl/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Publication
24385581 | J:206362
First Author: Çolakoğlu G
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Contactin-1 regulates myelination and nodal/paranodal domain organization in the central nervous system.
Volume: 111
Issue: 3
Pages: E394-403
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Publication
23645679 | J:199594
First Author: Bankston AN
Year: 2013
Journal: J Biol Chem
Title: p39, the primary activator for cyclin-dependent kinase 5 (Cdk5) in oligodendroglia, is essential for oligodendroglia differentiation and myelin repair.
Volume: 288
Issue: 25
Pages: 18047-57
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Publication
29459438 | J:261118
 
First Author: Colombo A
Year: 2018
Journal: EMBO J
Title: Non-cell-autonomous function of DR6 in Schwann cell proliferation.
Volume: 37
Issue: 7
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Allele
Tg(Plp1-Ccre)RFki | MGI:3833396
Name: transgene insertion R, Frank Kirchhoff
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
23291597 | J:259325
First Author: Ji Q
Year: 2013
Journal: Nat Immunol
Title: MHC class I-restricted myelin epitopes are cross-presented by Tip-DCs that promote determinant spreading to CD8⁺ T cells.
Volume: 14
Issue: 3
Pages: 254-61
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Publication
26645409 | J:316453
First Author: Myers KR
Year: 2016
Journal: Dev Neurobiol
Title: Oligodendroglial defects during quakingviable cerebellar development.
Volume: 76
Issue: 9
Pages: 972-82
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Publication
22984073 | J:187657
First Author: Makinodan M
Year: 2012
Journal: Science
Title: A critical period for social experience-dependent oligodendrocyte maturation and myelination.
Volume: 337
Issue: 6100
Pages: 1357-60
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Publication
22006952 | J:177714
First Author: Brill MS
Year: 2011
Journal: J Cell Biol
Title: Spatial constraints dictate glial territories at murine neuromuscular junctions.
Volume: 195
Issue: 2
Pages: 293-305
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Allele
Tg(Plp1-Ncre)DFki | MGI:3833395
Name: transgene insertion D, Frank Kirchhoff
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:5559044 | STOCK Tg(PLP1*)4Rsj/MoscJ
Attribute String: mutant stock, transgenic
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Publication
7505836 | J:161344
First Author: Mastronardi FG
Year: 1993
Journal: J Neurosci Res
Title: Demyelination in a transgenic mouse: a model for multiple sclerosis.
Volume: 36
Issue: 3
Pages: 315-24
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Publication
11830584 | J:76052
First Author: D'Souza CA
Year: 2002
Journal: J Biol Chem
Title: The up-regulation of stromelysin-1 (MMP-3) in a spontaneously demyelinating transgenic mouse precedes onset of disease.
Volume: 277
Issue: 16
Pages: 13589-96
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Publication
17079667 | J:114681
First Author: Mastronardi FG
Year: 2006
Journal: J Neurosci
Title: Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation.
Volume: 26
Issue: 44
Pages: 11387-96
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Publication
- | J:162843
 
First Author: Mastronardi FG
Year: 1993
Journal: Trans Am Soc Neurochem
Title: Demyelination in a transgenic mouse: A model for MS
Volume: Abstr 75
Pages: 130
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Publication
15128833 | J:89858
First Author: Mastronardi FG
Year: 2004
Journal: J Immunol
Title: Attenuation of experimental autoimmune encephalomyelitis and nonimmune demyelination by IFN-beta plus vitamin B12: treatment to modify notch-1/sonic hedgehog balance.
Volume: 172
Issue: 10
Pages: 6418-26
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Publication
21228378 | J:171534
First Author: Enriquez-Algeciras M
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Evaluation of a transgenic mouse model of multiple sclerosis with noninvasive methods.
Volume: 52
Issue: 5
Pages: 2405-11
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Publication
23281397 | J:194504
First Author: Enriquez-Algeciras M
Year: 2013
Journal: J Clin Invest
Title: Deimination restores inner retinal visual function in murine demyelinating disease.
Volume: 123
Issue: 2
Pages: 646-56
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Publication
8739149 | J:207524
First Author: Mastronardi FG
Year: 1996
Journal: J Neurosci Res
Title: Loss of myelin basic protein cationicity in DM20 transgenic mice is dosage dependent.
Volume: 44
Issue: 4
Pages: 301-7
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Publication
8739153 | J:33118
First Author: Mastronardi FG
Year: 1996
Journal: J Neurosci Res
Title: Myelin basic protein in experimental allergic encephalomyelitis is not affected at the posttranslational level: implications for demyelinating disease.
Volume: 44
Issue: 4
Pages: 344-9
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Publication
8567954 | J:30862
First Author: Mastronardi FG
Year: 1996
Journal: J Clin Invest
Title: Modifications of myelin basic protein in DM20 transgenic mice are similar to those in myelin basic protein from multiple sclerosis.
Volume: 97
Issue: 2
Pages: 349-58
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Genotype
Genotype
Symbol: Tg(PLP1*)4Rsj/?
Background: involves: CD-1
Zygosity: ot
Has Mutant Allele: true
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HT Experiment
GSE150150 | Transcriptional landscape of fate choices in the sensory lineages
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE208683 | Single-nuclei transcriptome sequencing of 5xFAD mouse brain hemisphere with myelin dysfunction
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE178296 | Transcriptome profiling of mouse brain microglia in Cnp null mice with 5xFAD background
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE178295 | Single-nuclei transcriptome sequencing of mouse grey and white matter under myelin abnormalities
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
33649472 | J:305223
First Author: Hamabe-Horiike T
Year: 2021
Journal: Sci Rep
Title: Glial cell type-specific gene expression in the mouse cerebrum using the piggyBac system and in utero electroporation.
Volume: 11
Issue: 1
Pages: 4864
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Publication
29107990 | J:252223
First Author: Abi Ghanem C
Year: 2017
Journal: PLoS Genet
Title: Long-lasting masculinizing effects of postnatal androgens on myelin governed by the brain androgen receptor.
Volume: 13
Issue: 11
Pages: e1007049
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Publication
28234971 | J:246666
First Author: Carr L
Year: 2017
Journal: PLoS One
Title: Expression patterns of Slit and Robo family members in adult mouse spinal cord and peripheral nervous system.
Volume: 12
Issue: 2
Pages: e0172736
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Publication
24449917 | J:206570
First Author: Chan CB
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PIKE is essential for oligodendroglia development and CNS myelination.
Volume: 111
Issue: 5
Pages: 1993-8
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Publication
37188512 | J:350443
First Author: Jiang C
Year: 2023
Journal: J Neurosci
Title: ADAMTS4 Enhances Oligodendrocyte Differentiation and Remyelination by Cleaving NG2 Proteoglycan and Attenuating PDGFRα Signaling.
Volume: 43
Issue: 24
Pages: 4405-4417
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Publication
21850021 | J:180641
First Author: Colombo S
Year: 2012
Journal: J Invest Dermatol
Title: Transcriptomic analysis of mouse embryonic skin cells reveals previously unreported genes expressed in melanoblasts.
Volume: 132
Issue: 1
Pages: 170-8
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Publication
26676415 | J:233845
First Author: Marteyn A
Year: 2016
Journal: Stem Cells
Title: Modulation of the Innate Immune Response by Human Neural Precursors Prevails over Oligodendrocyte Progenitor Remyelination to Rescue a Severe Model of Pelizaeus-Merzbacher Disease.
Volume: 34
Issue: 4
Pages: 984-96
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Publication
22706386 | J:187507
First Author: Saher G
Year: 2012
Journal: Nat Med
Title: Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet.
Volume: 18
Issue: 7
Pages: 1130-5
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Publication
27922816 | J:315580
First Author: Choi CI
Year: 2016
Journal: Aging (Albany NY)
Title: The progeroid gene BubR1 regulates axon myelination and motor function.
Volume: 8
Issue: 11
Pages: 2667-2688
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Publication
23864668 | J:199809
First Author: Clark K
Year: 2013
Journal: J Neurosci
Title: Gait abnormalities and progressive myelin degeneration in a new murine model of Pelizaeus-Merzbacher disease with tandem genomic duplication.
Volume: 33
Issue: 29
Pages: 11788-99
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Publication
31092737 | J:292977
 
First Author: Li H
Year: 2019
Journal: JCI Insight
Title: Gene suppressing therapy for Pelizaeus-Merzbacher disease using artificial microRNA.
Volume: 4
Issue: 10
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Publication
24680886 | J:227871
First Author: Prukop T
Year: 2014
Journal: Am J Hum Genet
Title: Progesterone antagonist therapy in a Pelizaeus-Merzbacher mouse model.
Volume: 94
Issue: 4
Pages: 533-46
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Publication
36928528 | J:357208
First Author: Lebrigand K
Year: 2023
Journal: Nucleic Acids Res
Title: The spatial landscape of gene expression isoforms in tissue sections.
Volume: 51
Issue: 8
Pages: e47
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Publication
26119414 | J:356665
First Author: Rao M
Year: 2015
Journal: Glia
Title: Enteric glia express proteolipid protein 1 and are a transcriptionally unique population of glia in the mammalian nervous system.
Volume: 63
Issue: 11
Pages: 2040-2057
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HT Experiment
GSE80437 | RNA-sequencing of mouse knockout models for Cnp, Plp1, and Ugt8 in the frontal cortex and cerebellum
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
21948283 | J:248852
First Author: Zhu H
Year: 2012
Journal: Glia
Title: The QKI-PLP pathway controls SIRT2 abundance in CNS myelin.
Volume: 60
Issue: 1
Pages: 69-82
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Publication
28711628 | J:265111
First Author: Rao M
Year: 2017
Journal: Gastroenterology
Title: Enteric Glia Regulate Gastrointestinal Motility but Are Not Required for Maintenance of the Epithelium in Mice.
Volume: 153
Issue: 4
Pages: 1068-1081.e7
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Publication
19820996 | J:267933
First Author: Gómez-Casati ME
Year: 2010
Journal: J Assoc Res Otolaryngol
Title: Cell-specific inducible gene recombination in postnatal inner ear supporting cells and glia.
Volume: 11
Issue: 1
Pages: 19-26
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Publication
28821675 | J:248996
First Author: Yang Y
Year: 2017
Journal: J Neurosci
Title: Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17.
Volume: 37
Issue: 38
Pages: 9101-9115
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Publication
38016472 | J:360043
First Author: Tejwani L
Year: 2024
Journal: Neuron
Title: Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1.
Volume: 112
Issue: 3
Pages: 362-383.e15
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Publication
30517863 | J:271183
First Author: Rosenberg LH
Year: 2018
Journal: Cell Rep
Title: HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State.
Volume: 25
Issue: 10
Pages: 2755-2765.e5
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Publication
39524336 | J:358357
First Author: Tosolini AP
Year: 2024
Journal: iScience
Title: The node of Ranvier influences the in vivo axonal transport of mitochondria and signaling endosomes.
Volume: 27
Issue: 11
Pages: 111158
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Publication
37071991 | J:335877
First Author: Mezydlo A
Year: 2023
Journal: Neuron
Title: Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex.
Volume: 111
Issue: 11
Pages: 1748-1759.e8
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Publication
35372344 | J:323119
 
First Author: Renauld JM
Year: 2022
Journal: Front Cell Dev Biol
Title: Intermediate Cells of Dual Embryonic Origin Follow a Basal to Apical Gradient of Ingression Into the Lateral Wall of the Cochlea.
Volume: 10
Pages: 867153
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Publication
36857184 | J:334127
First Author: Guyer RA
Year: 2023
Journal: Cell Rep
Title: Single-cell multiome sequencing clarifies enteric glial diversity and identifies an intraganglionic population poised for neurogenesis.
Volume: 42
Issue: 3
Pages: 112194
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Publication
23118341 | J:194698
First Author: Moscarello MA
Year: 2013
Journal: Dis Model Mech
Title: Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis.
Volume: 6
Issue: 2
Pages: 467-78
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Publication
29678817 | J:264116
 
First Author: Nagy N
Year: 2018
Journal: Development
Title: Collagen 18 and agrin are secreted by neural crest cells to remodel their microenvironment and regulate their migration during enteric nervous system development.
Volume: 145
Issue: 9
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Publication
38291527 | J:358306
First Author: Asbelaoui N
Year: 2024
Journal: Acta Neuropathol Commun
Title: Interplay between androgen and CXCR4 chemokine signaling in myelin repair.
Volume: 12
Issue: 1
Pages: 18
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Publication
36982286 | J:352919
 
First Author: Ott LC
Year: 2023
Journal: Int J Mol Sci
Title: Bone Marrow Stem Cells Derived from Nerves Have Neurogenic Properties and Potential Utility for Regenerative Therapy.
Volume: 24
Issue: 6
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Publication
36779913 | J:334253
 
First Author: Stavely R
Year: 2023
Journal: Development
Title: A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development.
Volume: 150
Issue: 5
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Publication
33335032 | J:299273
 
First Author: Yang SM
Year: 2020
Journal: Science
Title: Neuron class-specific responses govern adaptive myelin remodeling in the neocortex.
Volume: 370
Issue: 6523
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Plp1-Ncre)DFki/? Tg(Plp1-Ccre)RFki/?
Background: involves: 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(GFAP-Ncre)VFki/? Tg(Plp1-Ccre)RFki/?
Background: involves: 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
- | J:323554
     
First Author: Hassler T
Year: 2020
Journal: Ludwig-Maximilians-University Munich
Title: How central tolerance shapes the polyclonal CD4 T cell repertoire specific for the central nervous system antigen myelin proteolipid protein 1.
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Publication
31167127 | J:286939
First Author: Zonouzi M
Year: 2019
Journal: Cell Rep
Title: Individual Oligodendrocytes Show Bias for Inhibitory Axons in the Neocortex.
Volume: 27
Issue: 10
Pages: 2799-2808.e3
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Publication
34469751 | J:349558
First Author: Tasdemir-Yilmaz OE
Year: 2021
Journal: Dev Cell
Title: Diversity of developing peripheral glia revealed by single-cell RNA sequencing.
Volume: 56
Issue: 17
Pages: 2516-2535.e8
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Publication
30679375 | J:272493
First Author: Favuzzi E
Year: 2019
Journal: Science
Title: Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits.
Volume: 363
Issue: 6425
Pages: 413-417
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Journal: Neuron
Title: Mature enteric neurons have the capacity to reinnervate the intestine with glial cells as their guide.
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First Author: Hirrlinger J
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Journal: PLoS One
Title: Split-cre complementation indicates coincident activity of different genes in vivo.
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Year: 2018
Journal: Development
Title: The regulation of the homeostasis and regeneration of peripheral nerve is distinct from the CNS and independent of a stem cell population.
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First Author: Mueller JL
Year: 2024
Journal: Cell Rep
Title: Highly neurogenic glia from human and mouse myenteric ganglia generate functional neurons following culture and transplantation into the gut.
Volume: 43
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Pages: 114919
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37699522 | J:352361
First Author: Manion J
Year: 2023
Journal: Nature
Title: C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation.
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36070775 | J:330584
First Author: Hamnett R
Year: 2022
Journal: Curr Biol
Title: Regional cytoarchitecture of the adult and developing mouse enteric nervous system.
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First Author: Handler A
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Journal: Neuron
Title: Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch.
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39215998 | J:359257
First Author: Zhang L
Year: 2024
Journal: Cell Rep
Title: Trigeminal innervation and tactile responses in mouse tongue.
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Pages: 114665
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