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Search results 1301 to 1400 out of 5063 for Pole

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein Coding Gene
MGI:2135610 | Dync1li1
Type: protein_coding_gene
Organism: mouse, laboratory
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Pseudogene
MGI:3648694 | Ccnb1-ps
Type: pseudogene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1923294 | Ncapg2
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Cat4<Apcat1-2> | MGI:1856586
 
Name: dominant cataract 4; anisocoria
Allele Type: Radiation induced
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Allele
Acc | MGI:1856662
 
Name: anterior capsular cataract
Allele Type: Radiation induced
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Heritable Phenotypic Marker
MGI:97510 | Pcs1
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Allele
Pax6<2Neu> | MGI:2156812
 
Name: paired box 6; 2, Neuherberg
Allele Type: Chemically induced (ENU)
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Allele
Pax6<5Neu> | MGI:2156817
 
Name: paired box 6; 5, Neuherberg
Allele Type: Chemically induced (ENU)
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Allele
Pax6<6Neu> | MGI:2156818
 
Name: paired box 6; 6, Neuherberg
Allele Type: Chemically induced (ENU)
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Allele
Foxe3<rct> | MGI:2387330
Name: forkhead box E3; Rinshoken cataract
Allele Type: Spontaneous
Attribute String: Modified regulatory region
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Allele
Dmbt1<tm1Qaa> | MGI:3497714
Name: deleted in malignant brain tumors 1; targeted mutation 1, Qais Al-Awqati
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Sox2<tm1.2Vlcg> | MGI:5464909
Name: SRY (sex determining region Y)-box 2; targeted mutation 1.2, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Genotype
Genotype
Symbol: Acc/Acc<+>
Background: involves: 101 * C3H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ncapg2/Ncapg2
Background: involves: 129S1/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cat4/Cat4<+>
Background: involves: 101 * C3H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cat4/Cat4<+>
Background: involves: 101 * C3H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gje1/Gje1<+>
Background: involves: C3HeB/FeJ
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kdm1a/Kdm1a
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pcs1/Pcs1<+>
Background: involves: 101 * C3H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Atoh1/Atoh1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agtpbp1/Agtpbp1
Background: involves: C57BR/cdJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hoxb1/Hoxb1
Background: B6.129S2-Hoxb1/Cnrm
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hoxa2/Hoxa2 H2az2/H2az2<+>
Background: involves: 129S2/SvPas * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pold3/Pold3
Background: involves: C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Protein Coding Gene
MGI:1859866 | Cdc20
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1099790 | Plk2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1321161 | Ppp2cb
Type: protein_coding_gene
Organism: mouse, laboratory
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HT Experiment
GSE25675 | Identification and functional analysis of novel genes expressed in the Anterior Visceral Endoderm
Series Id: E-GEOD-25675
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: GEO
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GO Term
GO:0005814 | centriole
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GO Term
GO:0020009 | microneme
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GO Term
GO:0060832 | oocyte animal/vegetal axis specification
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Protein Coding Gene
MGI:107926 | Rock2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:107745 | Dctn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8C5N5
Organism: Mus musculus/domesticus
Length: 364  
Fragment?: false
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Protein
E0CX17
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: false
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Protein
Q6RI66
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: true
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Publication
16585273 | -
First Author: Saito TT
Year: 2006
Journal: J Cell Biol
Title: Mcp5, a meiotic cell cortex protein, is required for nuclear movement mediated by dynein and microtubules in fission yeast.
Volume: 173
Issue: 1
Pages: 27-33
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Publication
16039591 | -
First Author: D'Aquino KE
Year: 2005
Journal: Mol Cell
Title: The protein kinase Kin4 inhibits exit from mitosis in response to spindle position defects.
Volume: 19
Issue: 2
Pages: 223-34
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Publication
16039590 | -
First Author: Pereira G
Year: 2005
Journal: Mol Cell
Title: Kin4 kinase delays mitotic exit in response to spindle alignment defects.
Volume: 19
Issue: 2
Pages: 209-21
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Publication
19605686 | -
First Author: Chan LY
Year: 2009
Journal: Genes Dev
Title: The protein phosphatase 2A functions in the spindle position checkpoint by regulating the checkpoint kinase Kin4.
Volume: 23
Issue: 14
Pages: 1639-49
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Publication
15821139 | -
First Author: Bimbó A
Year: 2005
Journal: Eukaryot Cell
Title: Systematic deletion analysis of fission yeast protein kinases.
Volume: 4
Issue: 4
Pages: 799-813
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Publication
20855503 | -
First Author: Caydasi AK
Year: 2010
Journal: J Cell Biol
Title: Elm1 kinase activates the spindle position checkpoint kinase Kin4.
Volume: 190
Issue: 6
Pages: 975-89
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Publication
17569668 | -
First Author: Li YF
Year: 2007
Journal: J Biol Chem
Title: A receptor-binding site as revealed by the crystal structure of CfaE, the colonization factor antigen I fimbrial adhesin of enterotoxigenic Escherichia coli.
Volume: 282
Issue: 33
Pages: 23970-80
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Publication
23393133 | -
First Author: Liu Y
Year: 2013
Journal: J Biol Chem
Title: Tight conformational coupling between the domains of the enterotoxigenic Escherichia coli fimbrial adhesin CfaE regulates binding state transition.
Volume: 288
Issue: 14
Pages: 9993-10001
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Protein Domain
IPR034674 | STK_Kin4/ppk1
Type: Domain
Description: Saccharomyces cerevisiae Kin4 is a central component of the spindle position checkpoint (SPOC), which monitors spindle position and regulates the mitotic exit network (MEN) [, ]. Kin4 associates with spindle pole bodies in mother cells to inhibit MEN signaling and delay mitosis until the anaphase nucleus is properly positioned along the mother-bud axis. Kin4 activity is regulated by both the bud neck-associated kinase Elm1 and protein phosphatase 2A [, ].The fission yeast homologue is known as ppk1 [].
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Protein Domain
IPR024774 | PH_dom-Mcp5-type
Type: Domain
Description: This pleckstrin homology domain is found in eukaryotic proteins, including Mcp5, a fungal protein that anchors dynein at the cell cortex during the horsetail phase (prophase I) of meiosis. During prophase I of fission yeast all the telomeres become bundled at the spindle pole body and subsequently the nucleus undergoes a dynamic oscillation, resulting in elongated nuclear morphology known as "horsetail"nucleus. The pleckstrin homology domain is necessary for the cortical localisation of the Mcp5 protein during meiosis [].
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Protein Domain
IPR007320 | PDCD2_C
Type: Domain
Description: PDCD2 is localized predominantly in the cytosol of cells situated at the opposite pole of the germinal centre from the centroblasts as well as in cells in the mantle zone. It has been shown to interact with BCL6, an evolutionarily conserved Kruppel-type zinc finger protein that functions as a strong transcriptional repressor and is required for germinal centre development. The rat homologue, Rp8, is associated with programmed cell death in thymocytes.
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Protein Domain
IPR005301 | MOB_kinase_act_fam
Type: Family
Description: The MOB kinase activator family includes MOB1, an essential Saccharomyces cerevisiae protein, identified from a two-hybrid screen, that binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Conditional alleles of MOB1 cause a late nuclear division arrest at restrictive temperature []. This family also includes the MOB-like protein phocein, an intracellular protein that interacts with striatin and may play a role in membrane trafficking [].
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Protein Domain
IPR042614 | UBCD4_UBA
Type: Domain
Description: UbcD4, also called ubiquitin carrier protein or ubiquitin-protein ligase, is a class II E2 ubiquitin-conjugating enzyme encoded by Drosophila E2 gene which is only expressed in pole cells in embryos. It is a putative E2 enzyme homologous to the Huntingtin interacting protein-2 (HIP2) of human. UbcD4 specifically interacts with the polyubiquitin-binding subunit of the proteasome. It contains a C-terminal ubiquitin-associated (UBA) domain in addition to an N-terminal catalytic ubiquitin-conjugating enzyme E2 (UBCc) domain [].
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Protein Domain
IPR040941 | SAM_Exu
Type: Domain
Description: Exuperantia (Exu) is associated with localization of bicoid (bcd) mRNA and required for its localization at the anterior pole of the oocyte. Crystal structure of Exu reveals a dimeric assembly with each monomer consisting of a 3'-5' EXO-like domain and a sterile alpha motif (SAM)-like domain. The SAM-like domain interacts with its target RNA as a homodimer and is required for RNA binding activity [].
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Protein Domain
IPR043037 | CfaE_adhesin
Type: Homologous_superfamily
Description: CfaE, the tip adhesin of enterotoxigenic Escherichia coli colonisation factor antigen I fimbriae (CFA/I), initiates binding of this enteropathogen to the small intestine. It comprises a stacked N-terminal β-sandwich adhesin domain (AD) and a C-terminal pilin domain (PD), with the putative receptor-binding pocket at one pole and an equatorial interdomain interface [, ].This superfamily represents the adhesin domain of CfaE, homologous to the pilus biogenesis initiator protein CbID and the major pilin subunits of CS pili.
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Protein Coding Gene
MGI:2443665 | Numa1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1334448 | Aspm
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1859252 | Fmn2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1913963 | Actr2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:108466 | Ralbp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1858896 | Spast
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2444576 | Kif20b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1923036 | Ckap5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1923373 | Gpsm2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2384875 | Cdk5rap2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109604 | Plk3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1860374 | Mad2l1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1860493 | Arhgef7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2389572 | Brcc3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
37060937 | J:335233
 
First Author: Astrof S
Year: 2023
Journal: Dev Biol
Title: Aberrant differentiation of second heart field mesoderm prefigures cellular defects in the outflow tract in response to loss of FGF8.
Volume: 499
Pages: 10-21
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Publication
36989113 | J:334840
First Author: Ozguldez HO
Year: 2023
Journal: Cell Rep
Title: Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage.
Volume: 42
Issue: 4
Pages: 112313
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Publication
10415357 | J:56672
First Author: Haffner-Krausz R
Year: 1999
Journal: Mech Dev
Title: Expression of Fgfr2 in the early mouse embryo indicates its involvement in preimplantation development.
Volume: 85
Issue: 1-2
Pages: 167-72
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Publication
15963768 | J:103127
First Author: Szczepańska K
Year: 2005
Journal: Gene Expr Patterns
Title: LKB1/PAR4 protein is asymmetrically localized in mouse oocytes and associates with meiotic spindle.
Volume: 6
Issue: 1
Pages: 86-93
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Publication
14731449 | J:24909
First Author: Schiebel E
Year: 1995
Journal: Trends Cell Biol
Title: In search of a function for centrins.
Volume: 5
Issue: 5
Pages: 197-201
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Heritable Phenotypic Marker
MGI:87872 | Acc
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Allele
Apo | MGI:1856666
 
Name: anterior polar opacity
Allele Type: Radiation induced
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Allele
Pax6<7Neu> | MGI:2156738
 
Name: paired box 6; 7, Neuherberg
Allele Type: Chemically induced (ENU)
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Allele
Cops2<tm1Nwe> | MGI:2678281
Name: COP9 signalosome subunit 2; targeted mutation 1, Ning Wei
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Rbbp8<tm1Whl> | MGI:3577029
Name: retinoblastoma binding protein 8, endonuclease; targeted mutation 1, Wen-Hwa Lee
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Amelx<tm2Msnd> | MGI:3694787
Name: amelogenin, X-linked; targeted mutation 2, Malcolm L Snead
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Il17rd<Gt(KST223)Byg> | MGI:3709909
Name: interleukin 17 receptor D; gene trap KST223, BayGenomics
Allele Type: Gene trapped
Attribute String: Hypomorph, Reporter
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Allele
Hand2<tm1.2Zllr> | MGI:4453961
Name: heart and neural crest derivatives expressed 2; targeted mutation 1.2, Rolf Zeller
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Col4a1<ENU4004> | MGI:4822148
 
Name: collagen, type IV, alpha 1; ENU mutation 4004
Allele Type: Chemically induced (ENU)
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Allele
Col4a1<ENU6005> | MGI:4822157
 
Name: collagen, type IV, alpha 1; ENU mutation 6005
Allele Type: Chemically induced (ENU)
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Allele
Supv3l1<tm1Whle> | MGI:5469429
Name: suppressor of var1, 3-like 1 (S. cerevisiae); targeted mutation 1, Wen-Hwa Lee
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Med28<tm1.2Vra> | MGI:6111946
Name: mediator complex subunit 28; targeted mutation 1.2, Vijaya Ramesh
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Smarcc1/Smarcc1
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbbp8/Rbbp8
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax6<3Neu>/Pax6<+>
Background: either: (involves: 102 * C3H) or (involves: C3H)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax6<4Neu>/Pax6<+>
Background: either: (involves: 102 * C3H) or (involves: C3H)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Casp3/Casp3 Casp6/Casp6
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax6<7Neu>/Pax6<+>
Background: involves: 102 * C3H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxa2/Foxa2<+> Nodal/Nodal<+>
Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il17rd/Il17rd<+>
Background: B6.129P2-Il17rd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tbx6/Tbx6
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col4a1/Col4a1<+>
Background: C3.D2-Col4a1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox2/Sox2
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox2/Sox2
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
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MP Term
MP:0030512 | abnormal Tomes' process morphology
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Protein Coding Gene
MGI:1858202 | Rab11a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24030547 | J:316674
First Author: Moon HM
Year: 2014
Journal: Hum Mol Genet
Title: LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex.
Volume: 23
Issue: 2
Pages: 449-66
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Protein Coding Gene
MGI:1926137 | Sfi1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22516201 | J:183999
First Author: Ouseph MM
Year: 2012
Journal: Dev Cell
Title: Atypical E2F repressors and activators coordinate placental development.
Volume: 22
Issue: 4
Pages: 849-62
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Protein
A0A140LHH8
Organism: Mus musculus/domesticus
Length: 1919  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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