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Search results 1301 to 1400 out of 1688 for Prnp

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Type Details Score
HT Experiment
GSE221712 | Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer's Knock-in Mice Require Cellular Prion Protein
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
2109351 | J:173517
First Author: Oberdick J
Year: 1990
Journal: Science
Title: A promoter that drives transgene expression in cerebellar Purkinje and retinal bipolar neurons.
Volume: 248
Issue: 4952
Pages: 223-6
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Publication
18410407 | J:155720
First Author: Vidal R
Year: 2009
Journal: Brain Pathol
Title: Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2.
Volume: 19
Issue: 1
Pages: 58-68
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Allele
Tg(Prnp)1D4Lnq | MGI:2447139
Name: transgene insertion 1D4, Susan Lindquist
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-PRNP*129M)1Tkit | MGI:3762869
Name: transgene insertion 1, Tetsuyuki Kitamoto
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-PRNP)32Tkit | MGI:3762800
Name: transgene insertion 32, Tetsuyuki Kitamoto
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-PRNP*129V)139Tkit | MGI:3762801
Name: transgene insertion 139, Tetsuyuki Kitamoto
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-ITM2B*)1Ruvi | MGI:4415606
Name: transgene insertion 1, Ruben Vidal
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-PSEN2*N141I)30Jgr | MGI:4839766
Name: transgene insertion 30, J Richards
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
23438476 | J:195310
First Author: Ghaemmaghami S
Year: 2013
Journal: Am J Pathol
Title: Convergent replication of mouse synthetic prion strains.
Volume: 182
Issue: 3
Pages: 866-74
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Allele
Tg(PRNP-DNAJB2_ia)52aMec | MGI:5613188
Name: transgene insertion 52a, Michael E Cheetham
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6121816 | B6.Cg-Tg(PRNP-DNAJB2_ia)52aMec/MecH
Attribute String: mutant strain, congenic, transgenic
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Allele
Tg(PRNP-DNAJB2_ia)61aMec | MGI:5613160
Name: transgene insertion 61a, Michael E Cheetham
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6121817 | B6.Cg-Tg(PRNP-DNAJB2_ia)61aMec/MecH
Attribute String: mutant strain, congenic, transgenic
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Allele
Tg(PRNP)35Jcol | MGI:5760243
Name: transgene insertion 35, John Collinge
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(PRNP)45Jcol | MGI:5760245
Name: transgene insertion 45, John Collinge
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6429424 | C57BL/6JSmoc-Prnp<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Tg(Prnp-TARDBP)1Koya | MGI:7382830
Name: transgene insertion 1, Koji Yamanaka
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-Ldlr)BHol | MGI:7548804
Name: transgene insertion B, David M Holtzman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-Ldlr)EHol | MGI:7548807
Name: transgene insertion E, David M Holtzman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Prnp)4053Sbp/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Protein
Q9DBN4
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: false
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Protein
D3YXF2
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
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Protein
D3Z1F7
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
D3Z1U8
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: true
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Protein
D3YTM8
Organism: Mus musculus/domesticus
Length: 69  
Fragment?: true
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Publication
17032350 | -
First Author: Yokota T
Year: 2006
Journal: Eur J Clin Invest
Title: Brain site-specific gene expression analysis in Alzheimer's disease patients.
Volume: 36
Issue: 11
Pages: 820-30
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Protein Domain
IPR026759 | P33MONOX
Type: Family
Description: Proteins in this family are potential NADPH-dependent oxidoreductases. In human, it interacts with COBRA1, NOL12 and PRNP and may be involved in the regulation of neuronal survival, differentiation and axonal outgrowth []. It has been found down-regulated in the occipital lobe of an early stage Alzheimer's disease patients [].
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Allele
Tg(Prnp-PRNP*)1Tkit | MGI:3762868
Name: transgene insertion 1, Tetsuyuki Kitamoto
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Prnp<tm4(PRNP)Tkit> | MGI:3762786
Name: prion protein; targeted mutation 4, Tetsuyuki Kitamoto
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Publication
32075767 | J:288098
First Author: Rossi A
Year: 2020
Journal: Cell Rep
Title: Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer's Disease-Related Models.
Volume: 30
Issue: 7
Pages: 2332-2348.e10
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Publication
27239030 | J:238101
First Author: Filadi R
Year: 2016
Journal: Cell Rep
Title: Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2.
Volume: 15
Issue: 10
Pages: 2226-2238
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Strain
MGI:7386798 | B6.Cg-Tg(Prnp-TARDBP)1Koya/Koya
Attribute String: congenic, mutant strain, transgenic
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Allele
Tg(Prnp-TARDBP*R208)1Koya | MGI:7382863
Name: transgene insertion 1, Koji Yamanaka
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Prnp)1D4Lnq/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp)1D4Lnq/Tg(Prnp)1D4Lnq
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Publication
36229637 | J:334777
First Author: Jackson GS
Year: 2022
Journal: Sci Rep
Title: Overexpression of mouse prion protein in transgenic mice causes a non-transmissible spongiform encephalopathy.
Volume: 12
Issue: 1
Pages: 17198
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Allele
Prnp<tm1(PRNP)Tkit> | MGI:2681980
Name: prion protein; targeted mutation 1, Tetsuyuki Kitamoto
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Prnp<tm5(PRNP*)TKit> | MGI:3762867
Name: prion protein; targeted mutation 5, Tetsuyuki Kitamoto
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Prnp<tm2(PRNP*129M)Tkit> | MGI:3762784
Name: prion protein; targeted mutation 2, Tetsuyuki Kitamoto
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Prnp<tm3(PRNP*129V)Tkit> | MGI:3762785
Name: prion protein; targeted mutation 3, Tetsuyuki Kitamoto
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-PRNP*129V)144Tkit | MGI:3762802
Name: transgene insertion 144, Tetsuyuki Kitamoto
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:4415721 | B6.C3Fe-Tg(Prnp-ITM2B*)1Ruvi
Attribute String: congenic, mutant strain, transgenic
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Publication
28131015 | J:243142
 
First Author: Garringer HJ
Year: 2017
Journal: Neurobiol Aging
Title: Amyloid and intracellular accumulation of BRI2.
Volume: 52
Pages: 90-97
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Publication
32914559 | J:296936
First Author: Cisternas P
Year: 2020
Journal: Aging Cell
Title: Vascular amyloid accumulation alters the gabaergic synapse and induces hyperactivity in a model of cerebral amyloid angiopathy.
Volume: 19
Issue: 10
Pages: e13233
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Allele
Tg(Prnp-ITM2B*)6Jckr | MGI:4452484
Name: transgene insertion 6, Mathias Jucker
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-ITM2B*)1Ruvi/?
Background: B6.C3Fe-Tg(Prnp-ITM2B*)1Ruvi
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-ITM2B*)1Ruvi/Tg(Prnp-ITM2B*)1Ruvi
Background: involves: C3HeB/FeJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Allele
Tg(Prnp-MAPT)43Vle | MGI:2385566
Name: transgene insertion 43, Virginia M Y Lee
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-MAPT)7Vle | MGI:2385580
Name: transgene insertion 7, Virginia M Y Lee
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp)1Co | MGI:2387684
Name: transgene insertion 1, George A Carlson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-tTA)F959Sbp | MGI:2445786
Name: transgene insertion F959, Stanley B Prusiner
Allele Type: Transgenic
Attribute String: Transactivator
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Allele
Tg(Prnp)37Jcol | MGI:2446659
Name: transgene insertion 37, John Collinge
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp)46Jcol | MGI:2446663
Name: transgene insertion 46, John Collinge
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp)c35Cwe | MGI:2447134
Name: transgene insertion c35, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp)d11Cwe | MGI:2652550
Name: transgene insertion d11, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6145154 | B6.Cg-Prnp<tm1(PRNP)Tkik>/MokRbrc
Attribute String: mutant strain, congenic, targeted mutation
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Allele
Tg(PRNP)650Insra | MGI:3783297
Name: transgene insertion 650, Hubert Laude
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*D177N*M128V)A21Rchi | MGI:3836986
Name: transgene insertion A21, Roberto Chiesa
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz | MGI:4412048
Name: transgene insertion 152H, Laurence Ozmen
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-ITM2B*)7Jckr | MGI:4452483
Name: transgene insertion 7, Mathias Jucker
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:4452517 | C57BL/6-Tg(Prnp-ITM2B*)6Jckr
Attribute String: transgenic, mutant strain, coisogenic
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Allele
Tg(Prnp*)ADah | MGI:4462004
Name: transgene insertion A, David A Harris
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*)EDah | MGI:4462008
Name: transgene insertion E, David A Harris
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-EGFP)IX28Gsat | MGI:4847344
Name: transgene insertion IX28, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Prnp*P101L)2247Sbp | MGI:5491023
Name: transgene insertion 2247, Stanley B Prusiner
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*P101L)2866Sbp | MGI:5491025
Name: transgene insertion 2866, Stanley B Prusiner
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*P101L)2862Sbp | MGI:5491026
Name: transgene insertion 2862, Stanley B Prusiner
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
23965382 | J:288551
First Author: Lu D
Year: 2013
Journal: J Pharmacol Exp Ther
Title: Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice.
Volume: 347
Issue: 2
Pages: 325-38
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Allele
Prnp<tm1Wsj> | MGI:5606060
Name: prion protein; targeted mutation 1, Walker S Jackson
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Tg(tetO/Prnp-APP*Swe*Lon)9191Krz | MGI:5803807
Name: transgene insertion 9191, Kathleen R Zahs
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Tg(tetO/Prnp-MAPT)769Tli | MGI:5908815
Name: transgene insertion 769, Tong Li
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Tg(Prnp*)A3Dah | MGI:7564281
Name: transgene insertion A3, David A Harris
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*D177N*M128V)66Rchi | MGI:7564283
Name: transgene insertion 66, Roberto Chiesa
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-UBQLN2)WT-lowHlp | MGI:6784047
Name: transgene insertion WT-low, Henry L Paulson
Allele Type: Transgenic
Attribute String: Epitope tag, Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-UBQLN2)WT-hiHlp | MGI:6784070
Name: transgene insertion WT-hi, Henry L Paulson
Allele Type: Transgenic
Attribute String: Epitope tag, Humanized sequence, Inserted expressed sequence
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Strain
MGI:7386799 | B6.Cg-Tg(Prnp-TARDBP*R208)1Koya/Koya
Attribute String: congenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-ITM2B*)6Jckr/?
Background: C57BL/6-Tg(Prnp-ITM2B*)6Jckr
Zygosity: ot
Has Mutant Allele: true
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Publication
9730603 | J:49776
First Author: Iannuzzi L
Year: 1998
Journal: Cytogenet Cell Genet
Title: Comparative FISH-mapping of the prion protein gene (PRNP) on cattle, river buffalo, sheep and goat chromosomes.
Volume: 81
Issue: 3-4
Pages: 202-4
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Publication
18501713 | J:137029
First Author: Gallozzi M
Year: 2008
Journal: FEBS Lett
Title: Spatial and temporal down-regulation of transgene expression using the TRSID-silencer in mice: application to Prnp.
Volume: 582
Issue: 15
Pages: 2219-24
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Publication
36436561 | J:334360
First Author: Fernandez A
Year: 2023
Journal: J Biol Chem
Title: Lack of ApoE inhibits ADan amyloidosis in a mouse model of familial Danish dementia.
Volume: 299
Issue: 1
Pages: 102751
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Strain
MGI:2165256 | B6D2-Tg(Prnp-MAPT)43Vle/J
Attribute String: transgenic, mutant stock
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Publication
11159192 | J:67379
First Author: Ishihara T
Year: 2001
Journal: Am J Pathol
Title: Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice.
Volume: 158
Issue: 2
Pages: 555-62
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Strain
MGI:5314126 | STOCK Tg(Prnp-tTA)F959Sbp/J
Attribute String: transgenic, mutant stock
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Publication
19204377 | J:147292
First Author: Bao-Cutrona M
Year: 2009
Journal: Genetics
Title: Unexpected expression pattern of tetracycline-regulated transgenes in mice.
Volume: 181
Issue: 4
Pages: 1687-91
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Publication
28238655 | J:315925
First Author: Bastide A
Year: 2017
Journal: Curr Biol
Title: RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3.
Volume: 27
Issue: 5
Pages: 638-650
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Publication
32788341 | J:311705
 
First Author: Hughes DT
Year: 2020
Journal: Sci Signal
Title: Targeting the kinase insert loop of PERK selectively modulates PERK signaling without systemic toxicity in mice.
Volume: 13
Issue: 644
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Publication
22915766 | J:210078
First Author: Lygate CA
Year: 2012
Journal: Cardiovasc Res
Title: Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction.
Volume: 96
Issue: 3
Pages: 466-75
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Allele
Tg(Prnp-PG14)1Dah | MGI:2447086
Name: transgene insertion 1, David A Harris
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
- | J:55439
     
First Author: Chiesa R
Year: 1999
Title: A transgenic mouse model of a familial prion disease with an insertional mutation.
Pages: 569-580
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Allele
Tg(Prnp)a19Cwe | MGI:2447132
Name: transgene insertion a19, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp)a20Cwe | MGI:2447133
Name: transgene insertion a20, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp)F35Cwe | MGI:2652453
Name: transgene insertion F35, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Prnp<tm2Rcm> | MGI:2682351
Name: prion protein; targeted mutation 2, Richard C Moore
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Prnp/Prnd<tm1Aag> | MGI:3047634
Name: prion like protein doppel; targeted mutation 1, Adriano Aguzzi
Allele Type: Targeted
Attribute String: Null/knockout
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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