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Search results 1301 to 1400 out of 3113 for Rac1

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Hits by Strain

Type Details Score
Allele
Cyrib<tm1a(KOMP)Wtsi> | MGI:4948605
Name: CYFIP related Rac1 interactor B; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cyrib<Gt(535E12)Cmhd> | MGI:4958181
 
Name: CYFIP related Rac1 interactor B; gene trap 535E12, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST13187G3)Tigm> | MGI:5153447
 
Name: CYFIP related Rac1 interactor B; gene trap IST13187G3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST13165B6)Tigm> | MGI:5157470
 
Name: CYFIP related Rac1 interactor B; gene trap IST13165B6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyria<Gt(IST13250H5)Tigm> | MGI:5158029
 
Name: CYFIP related Rac1 interactor A; gene trap IST13250H5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST13220E9)Tigm> | MGI:5162799
 
Name: CYFIP related Rac1 interactor B; gene trap IST13220E9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyria<Gt(IST13362G9)Tigm> | MGI:5163562
 
Name: CYFIP related Rac1 interactor A; gene trap IST13362G9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST13414H2)Tigm> | MGI:5166942
 
Name: CYFIP related Rac1 interactor B; gene trap IST13414H2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST13400B5)Tigm> | MGI:5173611
 
Name: CYFIP related Rac1 interactor B; gene trap IST13400B5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyria<Gt(IST13455F3)Tigm> | MGI:5174164
 
Name: CYFIP related Rac1 interactor A; gene trap IST13455F3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST13459E11)Tigm> | MGI:5174398
 
Name: CYFIP related Rac1 interactor B; gene trap IST13459E11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST13615A7)Tigm> | MGI:5177299
 
Name: CYFIP related Rac1 interactor B; gene trap IST13615A7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyria<Gt(IST13632E4)Tigm> | MGI:5178962
 
Name: CYFIP related Rac1 interactor A; gene trap IST13632E4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST13855D9)Tigm> | MGI:5196333
 
Name: CYFIP related Rac1 interactor B; gene trap IST13855D9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14029E5)Tigm> | MGI:5207300
 
Name: CYFIP related Rac1 interactor B; gene trap IST14029E5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST13991D6)Tigm> | MGI:5208442
 
Name: CYFIP related Rac1 interactor B; gene trap IST13991D6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST13991A12)Tigm> | MGI:5208420
 
Name: CYFIP related Rac1 interactor B; gene trap IST13991A12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyria<Gt(IST14305A10)Tigm> | MGI:5220812
 
Name: CYFIP related Rac1 interactor A; gene trap IST14305A10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14309A3)Tigm> | MGI:5221112
 
Name: CYFIP related Rac1 interactor B; gene trap IST14309A3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14369H3)Tigm> | MGI:5225406
 
Name: CYFIP related Rac1 interactor B; gene trap IST14369H3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14496C1)Tigm> | MGI:5231803
 
Name: CYFIP related Rac1 interactor B; gene trap IST14496C1, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14472B5)Tigm> | MGI:5232987
 
Name: CYFIP related Rac1 interactor B; gene trap IST14472B5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14428B4)Tigm> | MGI:5236866
 
Name: CYFIP related Rac1 interactor B; gene trap IST14428B4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14537D2)Tigm> | MGI:5240467
 
Name: CYFIP related Rac1 interactor B; gene trap IST14537D2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14624F12)Tigm> | MGI:5244764
 
Name: CYFIP related Rac1 interactor B; gene trap IST14624F12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14602B6)Tigm> | MGI:5245384
 
Name: CYFIP related Rac1 interactor B; gene trap IST14602B6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14625H5)Tigm> | MGI:5245459
 
Name: CYFIP related Rac1 interactor B; gene trap IST14625H5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14613C6)Tigm> | MGI:5247417
 
Name: CYFIP related Rac1 interactor B; gene trap IST14613C6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14650B10)Tigm> | MGI:5249223
 
Name: CYFIP related Rac1 interactor B; gene trap IST14650B10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14813D9)Tigm> | MGI:5261562
 
Name: CYFIP related Rac1 interactor B; gene trap IST14813D9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14832C4)Tigm> | MGI:5264103
 
Name: CYFIP related Rac1 interactor B; gene trap IST14832C4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14917A11)Tigm> | MGI:5267438
 
Name: CYFIP related Rac1 interactor B; gene trap IST14917A11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14886D9)Tigm> | MGI:5268216
 
Name: CYFIP related Rac1 interactor B; gene trap IST14886D9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<Gt(IST14934E11)Tigm> | MGI:5270634
 
Name: CYFIP related Rac1 interactor B; gene trap IST14934E11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cyrib<tm1b(KOMP)Wtsi> | MGI:5605796
Name: CYFIP related Rac1 interactor B; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cyrib<tm1c(KOMP)Wtsi> | MGI:6316275
Name: CYFIP related Rac1 interactor B; targeted mutation 1c, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Cyria<em1(IMPC)Hmgu> | MGI:6414515
Name: CYFIP related Rac1 interactor A; endonuclease-mediated mutation 1, Helmholtz Zentrum Muenchen GmbH
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cyrib<tm1d(KOMP)Wtsi> | MGI:6444894
Name: CYFIP related Rac1 interactor B; targeted mutation 1d, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cyria<em1Gpt> | MGI:7297739
Name: CYFIP related Rac1 interactor A; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cyria<em3Gpt> | MGI:7297740
Name: CYFIP related Rac1 interactor A; endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cyrib<em1Gpt> | MGI:7297741
Name: CYFIP related Rac1 interactor B; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cyrib<em1Smoc> | MGI:7289259
Name: CYFIP related Rac1 interactor B; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cyrib<em2Smoc> | MGI:7289260
Name: CYFIP related Rac1 interactor B; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Cyrib/Cyrib
Background: involves: 129S1/Sv * 129X1/SvJ * DBA/2J
Zygosity: hm
Has Mutant Allele: true
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Publication
10637315 | J:60368
First Author: Kessels MM
Year: 2000
Journal: Mol Biol Cell
Title: Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation.
Volume: 11
Issue: 1
Pages: 393-412
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Publication
28232668 | J:350102
 
First Author: Yu Y
Year: 2017
Journal: Nat Commun
Title: Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity.
Volume: 8
Pages: 14364
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Publication
20696164 | -
First Author: Kärkkäinen S
Year: 2010
Journal: FEBS Lett
Title: POSH2 is a RING finger E3 ligase with Rac1 binding activity through a partial CRIB domain.
Volume: 584
Issue: 18
Pages: 3867-72
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Publication
10508610 | -
First Author: Västrik I
Year: 1999
Journal: Curr Biol
Title: Sema3A-induced growth-cone collapse is mediated by Rac1 amino acids 17-32.
Volume: 9
Issue: 18
Pages: 991-8
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Publication
17115053 | -
First Author: Jezyk MR
Year: 2006
Journal: Nat Struct Mol Biol
Title: Crystal structure of Rac1 bound to its effector phospholipase C-beta2.
Volume: 13
Issue: 12
Pages: 1135-40
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Allele
Rac1<em1Smoc> | MGI:7291958
Name: Rac family small GTPase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6334539 | C57BL/6N-Cyrib<tm1a(KOMP)Wtsi>/Tcp
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:5630331 | C57BL/6N-Cyrib<tm1b(KOMP)Wtsi>/Tcp
Attribute String: coisogenic, targeted mutation
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Strain
MGI:7414576 | C57BL/6NCrl-Cyria<em1(IMPC)Hmgu>/Ieg
Attribute String: coisogenic
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Strain
MGI:6770738 | C57BL/6JSmoc-Fam49B<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6770739 | C57BL/6JSmoc-Fam49bem2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Cyria/Cyria
Background: C57BL/6NCrl-Cyria/Ieg
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cyrib/Cyrib
Background: C57BL/6N-Cyrib/Tcp
Zygosity: hm
Has Mutant Allele: true
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Publication
17952876 | -
First Author: Lee SC
Year: 2007
Journal: Proteomics
Title: Dominant negative Rac1 attenuates paclitaxel-induced apoptosis in human melanoma cells through upregulation of heat shock protein 27: a functional proteomic analysis.
Volume: 7
Issue: 22
Pages: 4112-22
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Allele
Tg(Fabpl-RAC1-T17N)1Jig | MGI:2383956
Name: transgene insertion 1, Jeffrey I Gordon
Allele Type: Transgenic
Attribute String: Dominant negative, Inserted expressed sequence
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Publication
9285789 | -
First Author: Colomer V
Year: 1997
Journal: Hum Mol Genet
Title: Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain.
Volume: 6
Issue: 9
Pages: 1519-25
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Protein Coding Gene
MGI:104603 | Sh3bp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24294595 | -
 
First Author: Lin Y
Year: 2013
Journal: Biomed Res Int
Title: Angiopoietin-like 3 induces podocyte F-actin rearrangement through integrin α(V)β₃/FAK/PI3K pathway-mediated Rac1 activation.
Volume: 2013
Pages: 135608
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Publication
25925950 | -
First Author: Williamson RC
Year: 2015
Journal: J Biol Chem
Title: Coronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein Trafficking.
Volume: 290
Issue: 25
Pages: 15437-49
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Publication
21693584 | -
First Author: de Kreuk BJ
Year: 2011
Journal: J Cell Sci
Title: The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration.
Volume: 124
Issue: Pt 14
Pages: 2375-88
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Publication
11130063 | -
First Author: Worthylake DK
Year: 2000
Journal: Nature
Title: Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
Volume: 408
Issue: 6813
Pages: 682-8
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Publication
12912917 | -
First Author: Kawauchi T
Year: 2003
Journal: EMBO J
Title: The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration.
Volume: 22
Issue: 16
Pages: 4190-201
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Publication
19403692 | -
First Author: Hamill KJ
Year: 2009
Journal: Mol Biol Cell
Title: BPAG1e maintains keratinocyte polarity through beta4 integrin-mediated modulation of Rac1 and cofilin activities.
Volume: 20
Issue: 12
Pages: 2954-62
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Publication
23292607 | -
First Author: Wang ZG
Year: 2013
Journal: Oncol Rep
Title: Knockdown of Coronin-1C disrupts Rac1 activation and impairs tumorigenic potential in hepatocellular carcinoma cells.
Volume: 29
Issue: 3
Pages: 1066-72
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Publication
24819662 | -
First Author: Wang J
Year: 2014
Journal: Int J Gynecol Cancer
Title: Elmo1 helps dock180 to regulate Rac1 activity and cell migration of ovarian cancer.
Volume: 24
Issue: 5
Pages: 844-50
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Publication
18045877 | -
First Author: Ueda H
Year: 2008
Journal: J Biol Chem
Title: Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42.
Volume: 283
Issue: 4
Pages: 1946-53
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Publication
22614015 | -
First Author: Castillo-Lluva S
Year: 2013
Journal: Oncogene
Title: The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation.
Volume: 32
Issue: 13
Pages: 1735-42
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Genotype
Genotype
Symbol: Cyrib/Cyrib<+>
Background: C57BL/6N-Cyrib/Tcp
Zygosity: ht
Has Mutant Allele: true
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Publication
11420610 | J:70335
First Author: Purcell MK
Year: 2001
Journal: Mamm Genome
Title: Fine mapping of Ath6, a quantitative trait locus for atherosclerosis in mice.
Volume: 12
Issue: 7
Pages: 495-500
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Protein Coding Gene
MGI:1919143 | Noxo1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2449980 | Noxa1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19787194 | -
First Author: Araya N
Year: 2009
Journal: Int J Mol Med
Title: Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase.
Volume: 24
Issue: 5
Pages: 605-11
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Protein
Q5U465
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: false
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Protein
G3UWA1
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: false
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Protein Domain
IPR034608 | CCDC125
Type: Family
Description: Kenae/CCDC125 may act as a regulator of cell motility through RhoA, Rac1 and cdc42 [].
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Protein Coding Gene
MGI:2681162 | Nox3
Type: protein_coding_gene
Organism: mouse, laboratory
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GO Term
GO:0034741 | APC-tubulin-IQGAP1 complex
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GO Term
GO:0034743 | APC-IQGAP complex
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GO Term
GO:0034744 | APC-IQGAP1-Cdc42 complex
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GO Term
GO:0034745 | APC-IQGAP1-Rac1 complex
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Publication
17403031 | -
First Author: Bourguignon LY
Year: 2007
Journal: J Neurochem
Title: Hyaluronan-CD44 interaction stimulates Rac1 signaling and PKN gamma kinase activation leading to cytoskeleton function and cell migration in astrocytes.
Volume: 101
Issue: 4
Pages: 1002-17
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Publication
17196961 | -
First Author: Miyamoto Y
Year: 2007
Journal: Exp Cell Res
Title: Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth.
Volume: 313
Issue: 4
Pages: 791-804
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Publication
8223583 | -
First Author: Pick E
Year: 1993
Journal: Eur J Biochem
Title: Role of the rac1 p21-GDP-dissociation inhibitor for rho heterodimer in the activation of the superoxide-forming NADPH oxidase of macrophages.
Volume: 217
Issue: 1
Pages: 441-55
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Publication
15535843 | -
First Author: Paradiso A
Year: 2004
Journal: Breast Cancer Res
Title: The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells.
Volume: 6
Issue: 6
Pages: R616-28
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Publication
12065406 | -
First Author: Yoshida S
Year: 2002
Journal: EMBO J
Title: Shigella deliver an effector protein to trigger host microtubule destabilization, which promotes Rac1 activity and efficient bacterial internalization.
Volume: 21
Issue: 12
Pages: 2923-35
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Publication
14514689 | -
First Author: Owen D
Year: 2003
Journal: J Biol Chem
Title: Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1).
Volume: 278
Issue: 50
Pages: 50578-87
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Publication
16251354 | -
First Author: Khanday FA
Year: 2006
Journal: Mol Biol Cell
Title: Rac1 leads to phosphorylation-dependent increase in stability of the p66shc adaptor protein: role in Rac1-induced oxidative stress.
Volume: 17
Issue: 1
Pages: 122-9
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Publication
29127148 | -
First Author: Xiong Y
Year: 2017
Journal: J Immunol
Title: Ubc9 Binds to ADAP and Is Required for Rap1 Membrane Recruitment, Rac1 Activation, and Integrin-Mediated T Cell Adhesion.
Volume: 199
Issue: 12
Pages: 4142-4154
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Allele
Tg(Fabpl-RAC1-Q61L)1Jig | MGI:2383955
Name: transgene insertion 1, Jeffrey I Gordon
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Rac1-EGFP)JZ33Gsat | MGI:4847359
Name: transgene insertion JZ33, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Hprt1<tm1(tetO-EGFP/Rac1*)Shaw> | MGI:5559077
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Andrey S Shaw
Allele Type: Targeted
Attribute String: Constitutively active, Inducible, Inserted expressed sequence, Null/knockout, Reporter
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Allele
Tg(Krt14-Rac1*G12V)#Mrnk | MGI:6274278
Name: transgene insertion, M Peter Marinkovich
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Strain
MGI:6476136 | C57BL/6JSmoc-Rac1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Coding Gene
MGI:3036264 | Syde2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1917243 | Chn2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2443687 | Arhgap25
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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