| Type |
Details |
Score |
| Publication |
| First Author: |
Gregorieff A |
| Year: |
1998 |
| Journal: |
J Biol Chem |
| Title: |
Sequence requirements for association of protein-tyrosine phosphatase PEP with the Src homology 3 domain of inhibitory tyrosine protein kinase p50(csk). |
| Volume: |
273 |
| Issue: |
21 |
| Pages: |
13217-22 |
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•
•
•
•
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| Publication |
| First Author: |
van Vliet C |
| Year: |
2005 |
| Journal: |
Nat Immunol |
| Title: |
Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
253-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Barton CH |
| Year: |
1994 |
| Journal: |
J Exp Med |
| Title: |
NH2-terminal sequence of macrophage-expressed natural resistance-associated macrophage protein (Nramp) encodes a proline/serine-rich putative Src homology 3-binding domain. |
| Volume: |
179 |
| Issue: |
5 |
| Pages: |
1683-7 |
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•
•
•
•
•
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| Publication |
| First Author: |
Dos Santos C |
| Year: |
2013 |
| Journal: |
Blood |
| Title: |
The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents. |
| Volume: |
122 |
| Issue: |
11 |
| Pages: |
1900-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kenchappa RS |
| Year: |
2022 |
| Journal: |
Cell Rep |
| Title: |
Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma. |
| Volume: |
39 |
| Issue: |
12 |
| Pages: |
110991 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Futami M |
| Year: |
2011 |
| Journal: |
Blood |
| Title: |
G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase. |
| Volume: |
118 |
| Issue: |
4 |
| Pages: |
1077-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qian X |
| Year: |
2009 |
| Journal: |
Cancer Cell |
| Title: |
The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis. |
| Volume: |
16 |
| Issue: |
3 |
| Pages: |
246-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu Y |
| Year: |
2022 |
| Journal: |
PLoS Biol |
| Title: |
Occludin is a target of Src kinase and promotes lipid secretion by binding to BTN1a1 and XOR. |
| Volume: |
20 |
| Issue: |
1 |
| Pages: |
e3001518 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dai Z |
| Year: |
1998 |
| Journal: |
Genes Dev |
| Title: |
Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway. |
| Volume: |
12 |
| Issue: |
10 |
| Pages: |
1415-24 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Velling T |
| Year: |
2004 |
| Journal: |
EMBO Rep |
| Title: |
beta1-Integrins induce phosphorylation of Akt on serine 473 independently of focal adhesion kinase and Src family kinases. |
| Volume: |
5 |
| Issue: |
9 |
| Pages: |
901-5 |
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•
•
•
•
•
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| Publication |
| First Author: |
Ran H |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase. |
| Volume: |
114 |
| Issue: |
18 |
| Pages: |
4816-4821 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Raab M |
| Year: |
2010 |
| Journal: |
Immunity |
| Title: |
T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes. |
| Volume: |
32 |
| Issue: |
4 |
| Pages: |
541-56 |
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•
•
•
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| Publication |
| First Author: |
Mkaddem SB |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
246 |
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•
•
•
•
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| First Author: |
Freedman TS |
| Year: |
2015 |
| Journal: |
Elife |
| Title: |
LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. |
| Volume: |
4 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Ellis RW |
| Year: |
1981 |
| Journal: |
Nature |
| Title: |
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. |
| Volume: |
292 |
| Issue: |
5823 |
| Pages: |
506-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ciciliot S |
| Year: |
2015 |
| Journal: |
Diabetologia |
| Title: |
p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans. |
| Volume: |
58 |
| Issue: |
10 |
| Pages: |
2352-60 |
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•
•
•
•
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| Publication |
| First Author: |
Ranieri SC |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance. |
| Volume: |
107 |
| Issue: |
30 |
| Pages: |
13420-5 |
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•
•
•
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| First Author: |
Vashistha H |
| Year: |
2018 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Aging phenotype(s) in kidneys of diabetic mice are p66ShcA dependent. |
| Volume: |
315 |
| Issue: |
6 |
| Pages: |
F1833-F1842 |
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•
•
•
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| First Author: |
Tomilov A |
| Year: |
2016 |
| Journal: |
J Biol Chem |
| Title: |
p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria. |
| Volume: |
291 |
| Issue: |
24 |
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12575-85 |
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•
•
•
•
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| First Author: |
Berniakovich I |
| Year: |
2008 |
| Journal: |
J Biol Chem |
| Title: |
p66Shc-generated oxidative signal promotes fat accumulation. |
| Volume: |
283 |
| Issue: |
49 |
| Pages: |
34283-93 |
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•
•
•
•
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| First Author: |
Maxwell MJ |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
SHIP1 and Lyn Kinase Negatively Regulate Integrin alpha IIb beta 3 signaling in platelets. |
| Volume: |
279 |
| Issue: |
31 |
| Pages: |
32196-204 |
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•
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•
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| First Author: |
Kumar S |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction. |
| Volume: |
114 |
| Issue: |
7 |
| Pages: |
1714-1719 |
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| First Author: |
Hu J |
| Year: |
2006 |
| Journal: |
J Mol Biol |
| Title: |
Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS. |
| Volume: |
361 |
| Issue: |
1 |
| Pages: |
69-79 |
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| First Author: |
Shimomura Y |
| Year: |
2003 |
| Journal: |
J Dermatol Sci |
| Title: |
Gene expression of Sh3d19, a novel adaptor protein with five Src homology 3 domains, in anagen mouse hair follicles. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
43-51 |
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•
•
•
•
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| First Author: |
Martin A |
| Year: |
1999 |
| Journal: |
J Biol Chem |
| Title: |
Murine SHP-1 splice variants with altered Src homology 2 (SH2) domains. Implications for the SH2-mediated intramolecular regulation of SHP-1. |
| Volume: |
274 |
| Issue: |
31 |
| Pages: |
21725-34 |
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•
•
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| First Author: |
Okumura K |
| Year: |
1997 |
| Journal: |
Oncogene |
| Title: |
Expression of a novel isoform of Vav, Vav-T, containing a single Src homology 3 domain in murine testicular germ cells. |
| Volume: |
14 |
| Issue: |
6 |
| Pages: |
713-20 |
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•
•
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| First Author: |
Honda Z |
| Year: |
2009 |
| Journal: |
Genes Cells |
| Title: |
Identification of CENP-V as a novel microtubule-associating molecule that activates Src family kinases through SH3 domain interaction. |
| Volume: |
14 |
| Issue: |
12 |
| Pages: |
1383-94 |
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•
•
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| First Author: |
Carter JD |
| Year: |
2005 |
| Journal: |
J Immunol |
| Title: |
Deficiency of the Src homology region 2 domain-containing phosphatase 1 (SHP-1) causes enrichment of CD4+CD25+ regulatory T cells. |
| Volume: |
174 |
| Issue: |
11 |
| Pages: |
6627-38 |
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•
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| First Author: |
Nakata K |
| Year: |
2008 |
| Journal: |
J Immunol |
| Title: |
Positive and negative regulation of high affinity IgE receptor signaling by Src homology region 2 domain-containing phosphatase 1. |
| Volume: |
181 |
| Issue: |
8 |
| Pages: |
5414-24 |
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| First Author: |
Kruger J |
| Year: |
2000 |
| Journal: |
J Immunol |
| Title: |
Deficiency of Src homology 2-containing phosphatase 1 results in abnormalities in murine neutrophil function: studies in motheaten mice. |
| Volume: |
165 |
| Issue: |
10 |
| Pages: |
5847-59 |
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| First Author: |
Mao H |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygen. |
| Volume: |
8 |
| Issue: |
6 |
| Pages: |
e68143 |
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•
•
•
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| First Author: |
Agosti V |
| Year: |
2004 |
| Journal: |
J Exp Med |
| Title: |
Critical role for Kit-mediated Src kinase but not PI 3-kinase signaling in pro T and pro B cell development. |
| Volume: |
199 |
| Issue: |
6 |
| Pages: |
867-78 |
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•
•
•
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| First Author: |
Byun S |
| Year: |
2019 |
| Journal: |
J Biol Chem |
| Title: |
Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis. |
| Volume: |
294 |
| Issue: |
22 |
| Pages: |
8732-8744 |
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•
•
•
•
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| First Author: |
Sun C |
| Year: |
2012 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
A disintegrin and metalloproteinase 15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity. |
| Volume: |
32 |
| Issue: |
10 |
| Pages: |
2444-51 |
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•
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•
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| First Author: |
Nakamura K |
| Year: |
2002 |
| Journal: |
Blood |
| Title: |
The Src homology 2 domain-containing inositol 5-phosphatase negatively regulates Fcgamma receptor-mediated phagocytosis through immunoreceptor tyrosine-based activation motif-bearing phagocytic receptors. |
| Volume: |
100 |
| Issue: |
9 |
| Pages: |
3374-82 |
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| First Author: |
Chintala H |
| Year: |
2015 |
| Journal: |
Development |
| Title: |
The matricellular protein CCN1 controls retinal angiogenesis by targeting VEGF, Src homology 2 domain phosphatase-1 and Notch signaling. |
| Volume: |
142 |
| Issue: |
13 |
| Pages: |
2364-74 |
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•
•
•
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| First Author: |
Tazaki T |
| Year: |
2008 |
| Journal: |
Genes Cells |
| Title: |
Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice. |
| Volume: |
13 |
| Issue: |
2 |
| Pages: |
145-57 |
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| First Author: |
Mukherjee S |
| Year: |
2013 |
| Journal: |
Sci Signal |
| Title: |
Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases. |
| Volume: |
6 |
| Issue: |
256 |
| Pages: |
ra1 |
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•
•
•
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| First Author: |
Brauweiler A |
| Year: |
2000 |
| Journal: |
J Exp Med |
| Title: |
Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP). |
| Volume: |
191 |
| Issue: |
9 |
| Pages: |
1545-54 |
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•
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| First Author: |
Ponniah S |
| Year: |
1999 |
| Journal: |
Curr Biol |
| Title: |
Targeted disruption of the tyrosine phosphatase PTPalpha leads to constitutive downregulation of the kinases Src and Fyn. |
| Volume: |
9 |
| Issue: |
10 |
| Pages: |
535-8 |
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| First Author: |
Gomez Perdiguero E |
| Year: |
2016 |
| Journal: |
J Pathol |
| Title: |
ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2. |
| Volume: |
240 |
| Issue: |
4 |
| Pages: |
461-471 |
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•
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| First Author: |
Tada K |
| Year: |
2003 |
| Journal: |
J Immunol |
| Title: |
Tethering of apoptotic cells to phagocytes through binding of CD47 to Src homology 2 domain-bearing protein tyrosine phosphatase substrate-1. |
| Volume: |
171 |
| Issue: |
11 |
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5718-26 |
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| First Author: |
Osborn M |
| Year: |
1988 |
| Journal: |
Exp Cell Res |
| Title: |
The submembranous location of p11 and its interaction with the p36 substrate of pp60 src kinase in situ. |
| Volume: |
175 |
| Issue: |
1 |
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81-96 |
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| First Author: |
Zhang Z |
| Year: |
2004 |
| Journal: |
Mol Biol Cell |
| Title: |
The phosphorylation of vinculin on tyrosine residues 100 and 1065, mediated by SRC kinases, affects cell spreading. |
| Volume: |
15 |
| Issue: |
9 |
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| First Author: |
Abudula A |
| Year: |
2007 |
| Journal: |
J Biol Chem |
| Title: |
SLP-65 signal transduction requires Src homology 2 domain-mediated membrane anchoring and a kinase-independent adaptor function of Syk. |
| Volume: |
282 |
| Issue: |
39 |
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29059-66 |
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| First Author: |
Zhu C |
| Year: |
2008 |
| Journal: |
J Biol Chem |
| Title: |
Novel binding site for Src homology 2-containing protein-tyrosine phosphatase-1 in CD22 activated by B lymphocyte stimulation with antigen. |
| Volume: |
283 |
| Issue: |
3 |
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1653-9 |
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| First Author: |
Rao F |
| Year: |
2009 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Involvement of Src in L-type Ca2+ channel depression induced by macrophage migration inhibitory factor in atrial myocytes. |
| Volume: |
47 |
| Issue: |
5 |
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586-94 |
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Buitrago C |
| Year: |
2013 |
| Journal: |
J Steroid Biochem Mol Biol |
| Title: |
Role of VDR in 1α,25-dihydroxyvitamin D3-dependent non-genomic activation of MAPKs, Src and Akt in skeletal muscle cells. |
| Volume: |
136 |
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| First Author: |
Moreno-CÃ ceres J |
| Year: |
2016 |
| Journal: |
FEBS J |
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Caveolin-1-dependent activation of the metalloprotease TACE/ADAM17 by TGF-β in hepatocytes requires activation of Src and the NADPH oxidase NOX1. |
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| First Author: |
Ahuja P |
| Year: |
2023 |
| Journal: |
Hepatology |
| Title: |
Src homology 3 domain binding kinase 1 protects against hepatic steatosis and insulin resistance through the Nur77-FGF21 pathway. |
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| Issue: |
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Ramachandran IR |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
The phosphatase SRC homology region 2 domain-containing phosphatase-1 is an intrinsic central regulator of dendritic cell function. |
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Mota SI |
| Year: |
2014 |
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Exp Neurol |
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Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway. |
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261 |
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Cuddeback SM |
| Year: |
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J Biol Chem |
| Title: |
Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. |
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Deng Q |
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| Journal: |
Glia |
| Title: |
Astrocytic activation of A1 receptors regulates the surface expression of NMDA receptors through a Src kinase dependent pathway. |
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The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells. |
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Neural-specific inactivation of ShcA functions results in anatomical disorganization of subventricular zone neural stem cell niche in the adult brain. |
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A nonredundant role for the adapter protein Shc in thymic T cell development. |
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Circulation |
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Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility. |
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J Immunol |
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CXCL1/macrophage inflammatory protein-2-induced angiogenesis in vivo is mediated by neutrophil-derived vascular endothelial growth factor-A. |
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Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs. |
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Cutting Edge: Deletion of Ezrin in B Cells of Lyn-Deficient Mice Downregulates Lupus Pathology. |
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|
| Publication |
| First Author: |
Spindel ON |
| Year: |
2014 |
| Journal: |
Circ Res |
| Title: |
Thioredoxin-interacting protein is a biomechanical regulator of Src activity: key role in endothelial cell stress fiber formation. |
| Volume: |
114 |
| Issue: |
7 |
| Pages: |
1125-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kratchmarova I |
| Year: |
2001 |
| Journal: |
Gene |
| Title: |
Characterization of promoter region and genomic structure of the murine and human genes encoding Src like adapter protein. |
| Volume: |
262 |
| Issue: |
1-2 |
| Pages: |
267-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thouverey C |
| Year: |
2018 |
| Journal: |
Bone |
| Title: |
Selective inhibition of Src family kinases by SU6656 increases bone mass by uncoupling bone formation from resorption in mice. |
| Volume: |
113 |
|
| Pages: |
95-104 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheng M |
| Year: |
2015 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
A critical role of Src family kinase in SDF-1/CXCR4-mediated bone-marrow progenitor cell recruitment to the ischemic heart. |
| Volume: |
81 |
|
| Pages: |
49-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nguyen PH |
| Year: |
2016 |
| Journal: |
Cancer Cell |
| Title: |
LYN Kinase in the Tumor Microenvironment Is Essential for the Progression of Chronic Lymphocytic Leukemia. |
| Volume: |
30 |
| Issue: |
4 |
| Pages: |
610-622 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gottschalk TA |
| Year: |
2022 |
| Journal: |
Front Immunol |
| Title: |
Loss of CD11b Accelerates Lupus Nephritis in Lyn-Deficient Mice Without Disrupting Glomerular Leukocyte Trafficking. |
| Volume: |
13 |
|
| Pages: |
875359 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang K |
| Year: |
2011 |
| Journal: |
Cancer Res |
| Title: |
CD8+ T cells regulate bone tumor burden independent of osteoclast resorption. |
| Volume: |
71 |
| Issue: |
14 |
| Pages: |
4799-808 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ferry H |
| Year: |
2005 |
| Journal: |
Eur J Immunol |
| Title: |
Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival. |
| Volume: |
35 |
| Issue: |
12 |
| Pages: |
3655-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yuasa T |
| Year: |
2001 |
| Journal: |
J Exp Med |
| Title: |
Lyn is essential for fcgamma receptor III-mediated systemic anaphylaxis but not for the Arthus reaction. |
| Volume: |
193 |
| Issue: |
5 |
| Pages: |
563-72 |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
403
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Minchenberg SB |
| Year: |
2017 |
| Journal: |
J Neuroimmunol |
| Title: |
The control of oligodendrocyte bioenergetics by interferon-gamma (IFN-γ) and Src homology region 2 domain-containing phosphatase-1 (SHP-1). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Scolnick EM |
| Year: |
1979 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses. |
| Volume: |
76 |
| Issue: |
10 |
| Pages: |
5355-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang J |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
Regulation of the Src homology 2 domain-containing inositol 5'-phosphatase (SHIP1) by the cyclic AMP-dependent protein kinase. |
| Volume: |
284 |
| Issue: |
30 |
| Pages: |
20070-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giannotta M |
| Year: |
2012 |
| Journal: |
EMBO J |
| Title: |
The KDEL receptor couples to Gαq/11 to activate Src kinases and regulate transport through the Golgi. |
| Volume: |
31 |
| Issue: |
13 |
| Pages: |
2869-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kourtidis A |
| Year: |
2015 |
| Journal: |
Nat Cell Biol |
| Title: |
Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120Â catenin activity. |
| Volume: |
17 |
| Issue: |
9 |
| Pages: |
1145-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhu Z |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling. |
| Volume: |
110 |
| Issue: |
14 |
| Pages: |
E1282-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
D'Arco M |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
The C-terminal Src inhibitory kinase (Csk)-mediated tyrosine phosphorylation is a novel molecular mechanism to limit P2X3 receptor function in mouse sensory neurons. |
| Volume: |
284 |
| Issue: |
32 |
| Pages: |
21393-401 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morris CM |
| Year: |
1989 |
| Journal: |
Blood |
| Title: |
Localization of the SRC oncogene to chromosome band 20q11.2 and loss of this gene with deletion (20q) in two leukemic patients. |
| Volume: |
74 |
| Issue: |
5 |
| Pages: |
1768-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Costinean S |
| Year: |
2009 |
| Journal: |
Blood |
| Title: |
Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic mice. |
| Volume: |
114 |
| Issue: |
7 |
| Pages: |
1374-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Caveggion E |
| Year: |
2003 |
| Journal: |
J Cell Physiol |
| Title: |
Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement. |
| Volume: |
195 |
| Issue: |
2 |
| Pages: |
276-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kato M |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP. |
| Volume: |
275 |
| Issue: |
48 |
| Pages: |
37481-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Braverman LE |
| Year: |
1999 |
| Journal: |
J Biol Chem |
| Title: |
Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck. |
| Volume: |
274 |
| Issue: |
9 |
| Pages: |
5542-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Riento K |
| Year: |
2009 |
| Journal: |
J Cell Sci |
| Title: |
Endocytosis of flotillin-1 and flotillin-2 is regulated by Fyn kinase. |
| Volume: |
122 |
| Issue: |
Pt 7 |
| Pages: |
912-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boggon TJ |
| Year: |
2004 |
| Journal: |
Oncogene |
| Title: |
Structure and regulation of Src family kinases. |
| Volume: |
23 |
| Issue: |
48 |
| Pages: |
7918-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shaban L |
| Year: |
2020 |
| Journal: |
PLoS Pathog |
| Title: |
Yersinia pseudotuberculosis YopH targets SKAP2-dependent and independent signaling pathways to block neutrophil antimicrobial mechanisms during infection. |
| Volume: |
16 |
| Issue: |
5 |
| Pages: |
e1008576 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nguyen GT |
| Year: |
2020 |
| Journal: |
Elife |
| Title: |
SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst. |
| Volume: |
9 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bock F |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc. |
| Volume: |
110 |
| Issue: |
2 |
| Pages: |
648-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kliche S |
| Year: |
2012 |
| Journal: |
Blood |
| Title: |
CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules. |
| Volume: |
119 |
| Issue: |
3 |
| Pages: |
777-85 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(GFAP-SRC)1Aag/? |
| Background: |
involves: C3H * C57BL/6 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(GFAP-SRC)2Aag/? |
| Background: |
involves: C3H * C57BL/6 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(GFAP-SRC)3Aag/? |
| Background: |
involves: C3H * C57BL/6 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sweet DT |
| Year: |
2012 |
| Journal: |
Blood |
| Title: |
The adaptor protein Shc integrates growth factor and ECM signaling during postnatal angiogenesis. |
| Volume: |
119 |
| Issue: |
8 |
| Pages: |
1946-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He Q |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
7548 |
|
•
•
•
•
•
|