| Type |
Details |
Score |
| Publication |
| First Author: |
Brun P |
| Year: |
2015 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Toll like receptor-2 regulates production of glial-derived neurotrophic factors in murine intestinal smooth muscle cells. |
| Volume: |
68 |
|
| Pages: |
24-35 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
622
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miller G |
| Year: |
2011 |
| Journal: |
FASEB J |
| Title: |
Asparagine endopeptidase is required for normal kidney physiology and homeostasis. |
| Volume: |
25 |
| Issue: |
5 |
| Pages: |
1606-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rodríguez-Silvestre P |
| Year: |
2023 |
| Journal: |
Science |
| Title: |
Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells. |
| Volume: |
380 |
| Issue: |
6651 |
| Pages: |
1258-1265 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang SS |
| Year: |
2018 |
| Journal: |
EMBO J |
| Title: |
α-Synuclein stimulation of monoamine oxidase-B and legumain protease mediates the pathology of Parkinson's disease. |
| Volume: |
37 |
| Issue: |
12 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang J |
| Year: |
2024 |
| Journal: |
Brain Behav Immun |
| Title: |
A TrkB cleavage fragment in hippocampus promotes Depressive-Like behavior in mice. |
| Volume: |
119 |
|
| Pages: |
56-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pang L |
| Year: |
2023 |
| Journal: |
Cell Rep Med |
| Title: |
Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma. |
| Volume: |
4 |
| Issue: |
11 |
| Pages: |
101238 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zeeuwen PL |
| Year: |
2010 |
| Journal: |
FASEB J |
| Title: |
The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea. |
| Volume: |
24 |
| Issue: |
10 |
| Pages: |
3744-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang X |
| Year: |
2021 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
ADAM10 and ADAM17 are degraded by lysosomal pathway via asparagine endopeptidase. |
| Volume: |
537 |
|
| Pages: |
15-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang SS |
| Year: |
2020 |
| Journal: |
J Clin Invest |
| Title: |
Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus. |
| Volume: |
130 |
| Issue: |
1 |
| Pages: |
422-437 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang ZH |
| Year: |
2018 |
| Journal: |
JCI Insight |
| Title: |
BDNF inhibits neurodegenerative disease-associated asparaginyl endopeptidase activity via phosphorylation by AKT. |
| Volume: |
3 |
| Issue: |
16 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen G |
| Year: |
2021 |
| Journal: |
Sci Adv |
| Title: |
Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies. |
| Volume: |
7 |
| Issue: |
16 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu Z |
| Year: |
2020 |
| Journal: |
Prog Neurobiol |
| Title: |
Traumatic brain injury triggers APP and Tau cleavage by delta-secretase, mediating Alzheimer's disease pathology. |
| Volume: |
185 |
|
| Pages: |
101730 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang H |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Spatiotemporal activation of the C/EBPβ/δ-secretase axis regulates the pathogenesis of Alzheimer's disease. |
| Volume: |
115 |
| Issue: |
52 |
| Pages: |
E12427-E12434 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maehr R |
| Year: |
2005 |
| Journal: |
J Immunol |
| Title: |
Asparagine endopeptidase is not essential for class II MHC antigen presentation but is required for processing of cathepsin L in mice. |
| Volume: |
174 |
| Issue: |
11 |
| Pages: |
7066-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang SS |
| Year: |
2021 |
| Journal: |
Acta Neuropathol |
| Title: |
ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer's disease. |
| Volume: |
142 |
| Issue: |
1 |
| Pages: |
139-158 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stathopoulou C |
| Year: |
2018 |
| Journal: |
Immunity |
| Title: |
PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells. |
| Volume: |
49 |
| Issue: |
2 |
| Pages: |
247-263.e7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shirahama-Noda K |
| Year: |
2003 |
| Journal: |
J Biol Chem |
| Title: |
Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice. |
| Volume: |
278 |
| Issue: |
35 |
| Pages: |
33194-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maschalidi S |
| Year: |
2012 |
| Journal: |
PLoS Pathog |
| Title: |
Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation. |
| Volume: |
8 |
| Issue: |
8 |
| Pages: |
e1002841 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Feinstein E |
| Year: |
1995 |
| Journal: |
Trends Biochem Sci |
| Title: |
The death domain: a module shared by proteins with diverse cellular functions. |
| Volume: |
20 |
| Issue: |
9 |
| Pages: |
342-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bara AM |
| Year: |
2022 |
| Journal: |
Development |
| Title: |
Maf family transcription factors are required for nutrient uptake in the mouse neonatal gut. |
| Volume: |
149 |
| Issue: |
23 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abdallah BM |
| Year: |
2011 |
| Journal: |
J Bone Miner Res |
| Title: |
DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice. |
| Volume: |
26 |
| Issue: |
7 |
| Pages: |
1457-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Toronto Centre for Phenogenomics |
| Year: |
2013 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mammalian Functional Genomics Centre |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ko MS |
| Year: |
2000 |
| Journal: |
Development |
| Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
| Volume: |
127 |
| Issue: |
8 |
| Pages: |
1737-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dickinson ME |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
High-throughput discovery of novel developmental phenotypes. |
| Volume: |
537 |
| Issue: |
7621 |
| Pages: |
508-514 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen J |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
| Volume: |
100 |
| Issue: |
17 |
| Pages: |
9918-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thompson CL |
| Year: |
2014 |
| Journal: |
Neuron |
| Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
| Volume: |
83 |
| Issue: |
2 |
| Pages: |
309-323 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Knockout Mouse Consortium |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Mouse Strain Resource |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|