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Search results 1401 to 1500 out of 2017 for Bdnf

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Type Details Score
Protein Domain
IPR026144 | Neuritin_fam
Type: Family
Description: This entry represents the neuritin family of proteins, including neuritin-A and B from Xenopus laevis and neuritin-like protein from human and mouse. Neuritin has been shown to promote neurite outgrowth and arborisation in primary embryonic hippocampal and cortical cultures []. Its expression is induced by neuronal activity and by the activity-regulated neurotrophins BDNF and NT-3 [].
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Protein Domain
IPR029309 | CaRF
Type: Family
Description: This entry represents calcium-responsive transcription factor (CaRF, also known as amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) []. CaRF acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. It binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence [].
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HT Experiment
GSE227845 | Ontogeny and Trophic Factor Sensitivity of Gastrointestinal Projecting Vagal Sensory Cell Types
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
18086127 | J:135260
First Author: Gharami K
Year: 2008
Journal: J Neurochem
Title: Brain-derived neurotrophic factor over-expression in the forebrain ameliorates Huntington's disease phenotypes in mice.
Volume: 105
Issue: 2
Pages: 369-79
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Publication
27421068 | J:255831
First Author: Feng L
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Long-Term Protection of Retinal Ganglion Cells and Visual Function by Brain-Derived Neurotrophic Factor in Mice With Ocular Hypertension.
Volume: 57
Issue: 8
Pages: 3793-802
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Allele
Timo | MGI:3766100
 
Name: transgenic insertional mutants with obesity
Allele Type: Transgenic
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Genotype
Genotype
Symbol: Bdnf/Bdnf
Background: involves: 129S4/SvJae
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ntf3/Ntf3
Background: involves: 129S1/Sv
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col1a1/Col1a1 Tg(Sim1-cre)1Lowl/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Publication
16632412 | -
 
First Author: Lebrun B
Year: 2006
Journal: Auton Neurosci
Title: Brain-derived neurotrophic factor (BDNF) and food intake regulation: a minireview.
Volume: 126-127
Pages: 30-8
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Publication
17949819 | -
First Author: Kozisek ME
Year: 2008
Journal: Pharmacol Ther
Title: Brain-derived neurotrophic factor and its receptor tropomyosin-related kinase B in the mechanism of action of antidepressant therapies.
Volume: 117
Issue: 1
Pages: 30-51
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Protein Domain
IPR020430 | Brain-der_neurotrophic_factor
Type: Family
Description: During the development of the vertebrate nervous system, many neurons become redundant (because they have died, failed to connect to target cells, etc.) and are eliminated. At the same time, developing neurons send out axon outgrowths that contact their target cells []. Such cells control their degree of innervation (the number of axon connections) by the secretion of various specific neurotrophic factors that are essential for neuron survival. One of these is nerve growth factor (NGF), which is involved in the survival of some classes of embryonic neuron (e.g., peripheral sympathetic neurons) []. NGF is mostly found outside the central nervous system (CNS), but slight traces have been detected in adult CNS tissues, although a physiological role for this is unknown []; it has also been found in several snake venoms [, ]. Proteins similar to NGF include brain-derived neurotrophic factor (BDNF) and neurotrophins 3 to 7, all of which demonstrate neuron survival and outgrowth activities. Originally purified from pig brain [], the neurotrophin BDNF is expressed in a range of tissues and cell types in the CNS and periphery. It exerts its effects by binding to neurotrophic tyrosine kinase receptor type 2 (NTRK2; also called TrkB) and the low affinity nerve growth factor receptor, p75NTR. While the former receptor mediates the neurotrophin's prosurvival functions, activation of p75NTR by BDNF has been shown to promote apoptosis and to inhibit axonal growth []. BDNF is a key regulator of synaptic plasticity, and plays an important role in learning and memory []. Several lines of evidence suggest that it is also involved in the control of food intake and body weight []. A number of clinical studies have demonstrated an association between aberrant BDNF levels and disorders and disease states, such as depression, epilepsy, bipolar disorder, Parkinson's disease and Alzheimer's disease [].
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Publication
9034318 | J:38270
First Author: Arab SF
Year: 1997
Journal: Gene
Title: The gene encoding bovine brain-derived neurotrophic factor (BDNF).
Volume: 185
Issue: 1
Pages: 95-8
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Publication
12719380 | J:83437
First Author: Davy BE
Year: 2003
Journal: Hum Mol Genet
Title: Congenital hydrocephalus in hy3 mice is caused by a frameshift mutation in Hydin, a large novel gene.
Volume: 12
Issue: 10
Pages: 1163-70
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Publication
18250199 | J:135322
First Author: Lechtreck KF
Year: 2008
Journal: J Cell Biol
Title: Mutations in Hydin impair ciliary motility in mice.
Volume: 180
Issue: 3
Pages: 633-43
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Strain
MGI:3766604 | B6.Cg-Timo
Attribute String: mutant strain, insertion
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Genotype
Genotype
Symbol: Bdnf/Bdnf Ntrk2/Ntrk2
Background: involves: 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Timo/Timo<+>
Background: either: B6.Cg-Timo or (involves: C57BL/6J * CBA/CaJ)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Timo/Timo
Background: either: B6.Cg-Timo or (involves: C57BL/6J * CBA/CaJ)
Zygosity: hm
Has Mutant Allele: true
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Publication
11331584 | -
First Author: Nielsen MS
Year: 2001
Journal: EMBO J
Title: The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein.
Volume: 20
Issue: 9
Pages: 2180-90
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Protein Domain
IPR031777 | Sortilin_C
Type: Domain
Description: This domain is the C-terminal cytoplasmic tail of sortilin, a Vps10p domain-containing family of proteins [, ]. Most sortilin is expressed within intracellular compartments, where it chaperones diverse ligands, including proBDNF and acid hydrolases. The sortilin cytoplasmic tail is homologous to mannose 6-phosphate receptor and is required for the intracellular trafficking of cargo proteins via interactions with distinct adaptor molecules [, ]. In addition to mediating lysosomal targeting of specific acid hydrolases, the sortilin cytoplasmic tail also directs trafficking of BDNF to the secretory pathway in neurons, where it can be released in response to depolarisation to modulate cell survival and synaptic plasticity [].
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Publication
34463714 | J:324500
First Author: Javed S
Year: 2021
Journal: Hum Mol Genet
Title: Temporal dissection of Rai1 function reveals brain-derived neurotrophic factor as a potential therapeutic target for Smith-Magenis syndrome.
Volume: 31
Issue: 2
Pages: 275-288
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Publication
17611278 | J:122929
First Author: Liu X
Year: 2007
Journal: J Neurosci
Title: Brain-derived neurotrophic factor and TrkB modulate visual experience-dependent refinement of neuronal pathways in retina.
Volume: 27
Issue: 27
Pages: 7256-67
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HT Experiment
E-GEOD-38219 | Gene expression data from cortex of 15 week old wild type, R6/2, HDAC4het and R6/2::HDAC4het mice
Series Id: GSE38219
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-38218 | Gene expression data from cortex of 9 week old wild type, R6/2, HDAC4het and R6/2::HDAC4het mice
Series Id: GSE38218
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE168768 | Tbx1 regulates a cardiopharyngeal mesodermal niche in forming the heart and branchiomeric muscles [scRNA-Seq 3]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE158941 | Tbx1 regulates a cardiopharyngeal mesodermal niche in forming the heart and branchiomeric muscles [scRNA-Seq 1]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE167491 | Tbx1 regulates a cardiopharyngeal mesodermal niche in forming the heart and branchiomeric muscles [scRNA-Seq 2]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE186934 | Tbx1 regulates a cardiopharyngeal mesodermal niche in forming the heart and branchiomeric muscles [scRNA-Seq 4]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE209893 | Proteolysis resistant huntingtin isoform induced by antisense oligonucleotide maintains normal huntingtin function in mouse
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE84175 | RNA-seq of hippocampus from wild type and CTCF cko animals
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
11553291 | J:127897
First Author: Ritter AM
Year: 2001
Journal: Eur J Neurosci
Title: Excess target-derived neurotrophin-3 alters the segmental innervation of the skin.
Volume: 14
Issue: 3
Pages: 411-8
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Genotype
Genotype
Symbol: Col1a1/Col1a1<+> Mecp2/? Tg(Camk2a-cre)93Kln/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Protein
E2IUB1
Organism: Mus musculus/domesticus
Length: 42  
Fragment?: true
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Publication
21552261 | -
First Author: Tian Y
Year: 2011
Journal: Nat Struct Mol Biol
Title: Multimeric assembly and biochemical characterization of the Trax-translin endonuclease complex.
Volume: 18
Issue: 6
Pages: 658-64
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Publication
23650579 | -
 
First Author: Kumar V
Year: 2012
Journal: FEBS Open Bio
Title: Low-resolution structure of Drosophila translin.
Volume: 2
Pages: 37-46
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Publication
18424275 | -
First Author: Li Z
Year: 2008
Journal: Biochim Biophys Acta
Title: The Translin/Trax RNA binding complex: clues to function in the nervous system.
Volume: 1779
Issue: 8
Pages: 479-85
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Publication
20578993 | -
First Author: Jaendling A
Year: 2010
Journal: Biochem J
Title: Biological roles of translin and translin-associated factor-X: RNA metabolism comes to the fore.
Volume: 429
Issue: 2
Pages: 225-34
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Publication
27183912 | -
First Author: Gomez-Escobar N
Year: 2016
Journal: Oncotarget
Title: Translin and Trax differentially regulate telomere-associated transcript homeostasis.
Volume: 7
Issue: 23
Pages: 33809-20
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Protein Domain
IPR033956 | Translin
Type: Family
Description: Translin (also known as TB-RBP for Testis Brain RNA-binding protein, a mouse orthologue), is a paralogue of its binding partner protein TRAX (translin-associated factor-X) []and together they form oligomeric complexes known as C3PO proteins (for component 3 promoter of RNA-induced silencing complex or RISC) []. DNA damage has been proposed to stimulate transport of Translin into nuclei. It binds to RNA and single-stranded DNA, and its selectivity is modulated by interactions with GTP and TRAX. Translin may also regulate dendritic trafficking of BDNF RNAs as well as function as a key activator of siRNA-mediated silencing in Drosophila []. Translin and Trax participate in a variety of nucleic acid metabolism pathways in addition to RNAi and have been implicated in a wide range of biological activities, including mRNA processing, cell growth regulation, spermatogenesis, neuronal development/function, genome stability regulation and carcinogenesis [, , ]; however, their precise role in some of the processes remains unclear.
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HT Experiment
E-GEOD-80633 | Gene expression analysis in cortex of CRTC1 deficient mice and WT littermates
Series Id: GSE80633
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
17994015 | J:130774
First Author: Klein ME
Year: 2007
Journal: Nat Neurosci
Title: Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA.
Volume: 10
Issue: 12
Pages: 1513-4
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Publication
10085125 | -
First Author: Nielsen MS
Year: 1999
Journal: J Biol Chem
Title: Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase.
Volume: 274
Issue: 13
Pages: 8832-6
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Publication
2321006 | -
First Author: Maisonpierre PC
Year: 1990
Journal: Science
Title: Neurotrophin-3: a neurotrophic factor related to NGF and BDNF.
Volume: 247
Issue: 4949 Pt 1
Pages: 1446-51
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Publication
12914971 | -
First Author: Johnson RA
Year: 2003
Journal: Brain Res
Title: Exercise-induced changes in hippocampal brain-derived neurotrophic factor and neurotrophin-3: effects of rat strain.
Volume: 983
Issue: 1-2
Pages: 108-14
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Publication
14507970 | -
First Author: Arvanian VL
Year: 2003
Journal: J Neurosci
Title: Chronic neurotrophin-3 strengthens synaptic connections to motoneurons in the neonatal rat.
Volume: 23
Issue: 25
Pages: 8706-12
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Publication
14499950 | -
First Author: Ying Z
Year: 2003
Journal: Brain Res
Title: Voluntary exercise increases neurotrophin-3 and its receptor TrkC in the spinal cord.
Volume: 987
Issue: 1
Pages: 93-9
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Publication
14519521 | -
First Author: Granda B
Year: 2003
Journal: Brain Res
Title: Oleic acid induces GAP-43 expression through a protein kinase C-mediated mechanism that is independent of NGF but synergistic with NT-3 and NT-4/5.
Volume: 988
Issue: 1-2
Pages: 1-8
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Publication
19122660 | -
First Author: Quistgaard EM
Year: 2009
Journal: Nat Struct Mol Biol
Title: Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain.
Volume: 16
Issue: 1
Pages: 96-8
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Publication
9013611 | -
First Author: Petersen CM
Year: 1997
Journal: J Biol Chem
Title: Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography.
Volume: 272
Issue: 6
Pages: 3599-605
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Publication
9756851 | -
First Author: Mazella J
Year: 1998
Journal: J Biol Chem
Title: The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor.
Volume: 273
Issue: 41
Pages: 26273-6
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Protein Domain
IPR015578 | Neurotrophin-3
Type: Family
Description: During the development of the vertebrate nervous system, many neurons become redundant (because they have died, failed to connect to target cells, etc.) and are eliminated. At the same time, developing neurons send out axon outgrowths that contact their target cells []. Such cells control their degree of innervation (the number of axon connections) by the secretion of various specific neurotrophic factors that are essential for neuron survival. One of these is nerve growth factor (NGF or beta-NGF), a vertebrate protein that stimulates division and differentiation of sympathetic and embryonic sensory neurons [, ]. NGF is mostly found outside the central nervous system (CNS), but slight traces have been detected in adult CNS tissues, although a physiological role for this is unknown []; it has also been found in several snake venoms [, ].NGF is a protein of about 120 residues that is cleaved from a larger precursor molecule. It contains six cysteines all involved in intrachain disulphide bonds.Neurotrophin-3 is a neurotrophic factor related to NGF and BDNF []. NT-3 and its receptor TrkC are found in the spinal cord, and their expression is altered by voluntary exercise [, , ]. In the brain, NT-3 and NT-4/5 may function synergistically with oleic acid to increase GAP-43 expression [].
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Protein Coding Gene
MGI:99918 | Mecp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
9115743 | J:39081
First Author: Brunstrom JE
Year: 1997
Journal: Neuron
Title: Neuronal heterotopias in the developing cerebral cortex produced by neurotrophin-4.
Volume: 18
Issue: 3
Pages: 505-17
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Publication
18805096 | J:156046
First Author: Napoli I
Year: 2008
Journal: Cell
Title: The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.
Volume: 134
Issue: 6
Pages: 1042-54
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Publication
27605705 | J:239183
First Author: Xu C
Year: 2016
Journal: Mol Biol Cell
Title: Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth.
Volume: 27
Issue: 21
Pages: 3342-3356
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Publication
26275923 | J:227356
 
First Author: Schmidt M
Year: 2016
Journal: Behav Brain Res
Title: Morc1 knockout evokes a depression-like phenotype in mice.
Volume: 296
Pages: 7-14
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Publication
12367511 | J:130626
First Author: Minichiello L
Year: 2002
Journal: Neuron
Title: Mechanism of TrkB-mediated hippocampal long-term potentiation.
Volume: 36
Issue: 1
Pages: 121-37
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Publication
28352664 | J:290770
First Author: Pardo M
Year: 2017
Journal: JCI Insight
Title: Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice.
Volume: 2
Issue: 6
Pages: e91782
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Publication
16025106 | J:101447
First Author: Woo NH
Year: 2005
Journal: Nat Neurosci
Title: Activation of p75NTR by proBDNF facilitates hippocampal long-term depression.
Volume: 8
Issue: 8
Pages: 1069-77
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Publication
15128850 | J:96877
First Author: Gehler S
Year: 2004
Journal: J Neurosci
Title: p75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity.
Volume: 24
Issue: 18
Pages: 4363-72
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Publication
20368433 | J:159284
First Author: Namekata K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex.
Volume: 107
Issue: 16
Pages: 7586-91
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Publication
16427017 | J:166020
First Author: Riccio A
Year: 2006
Journal: Mol Cell
Title: A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons.
Volume: 21
Issue: 2
Pages: 283-94
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Publication
20298786 | J:163048
First Author: Kong L
Year: 2010
Journal: Neurobiol Dis
Title: Neuroprotective effect of overexpression of thioredoxin on photoreceptor degeneration in Tubby mice.
Volume: 38
Issue: 3
Pages: 446-55
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Publication
24302884 | J:205270
First Author: Mielcarek M
Year: 2013
Journal: PLoS Biol
Title: HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration.
Volume: 11
Issue: 11
Pages: e1001717
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Publication
12917366 | J:120211
First Author: Shalizi A
Year: 2003
Journal: J Neurosci
Title: Characterization of a neurotrophin signaling mechanism that mediates neuron survival in a temporally specific pattern.
Volume: 23
Issue: 19
Pages: 7326-36
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Publication
27746130 | J:253356
First Author: Vignoli B
Year: 2016
Journal: Neuron
Title: Peri-Synaptic Glia Recycles Brain-Derived Neurotrophic Factor for LTP Stabilization and Memory Retention.
Volume: 92
Issue: 4
Pages: 873-887
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Publication
21949401 | J:177465
First Author: Zheng K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: TrkB signaling in parvalbumin-positive interneurons is critical for gamma-band network synchronization in hippocampus.
Volume: 108
Issue: 41
Pages: 17201-6
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Publication
30323233 | J:267818
First Author: Zhang H
Year: 2018
Journal: Nat Commun
Title: Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington's disease models.
Volume: 9
Issue: 1
Pages: 4272
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Publication
20445044 | J:160562
First Author: He XP
Year: 2010
Journal: J Neurosci
Title: Disruption of TrkB-mediated phospholipase Cgamma signaling inhibits limbic epileptogenesis.
Volume: 30
Issue: 18
Pages: 6188-96
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Publication
27732862 | J:240767
First Author: Wang LL
Year: 2016
Journal: Cell Rep
Title: The p53 Pathway Controls SOX2-Mediated Reprogramming in the Adult Mouse Spinal Cord.
Volume: 17
Issue: 3
Pages: 891-903
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Publication
26402732 | J:246142
First Author: McDonald CR
Year: 2015
Journal: PLoS Pathog
Title: Experimental Malaria in Pregnancy Induces Neurocognitive Injury in Uninfected Offspring via a C5a-C5a Receptor Dependent Pathway.
Volume: 11
Issue: 9
Pages: e1005140
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Publication
31186474 | J:281479
First Author: Shin MK
Year: 2019
Journal: Sci Rep
Title: Ganglioside GQ1b ameliorates cognitive impairments in an Alzheimer's disease mouse model, and causes reduction of amyloid precursor protein.
Volume: 9
Issue: 1
Pages: 8512
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Publication
26842955 | J:236279
 
First Author: Tai DJ
Year: 2016
Journal: Nat Commun
Title: MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome.
Volume: 7
Pages: 10552
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Publication
30867511 | J:275597
First Author: Xie MJ
Year: 2019
Journal: Sci Rep
Title: PIP3-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover.
Volume: 9
Issue: 1
Pages: 4305
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Publication
38444608 | J:351636
First Author: Gölöncsér F
Year: 2024
Journal: iScience
Title: P2X7 receptor inhibition alleviates mania-like behavior independently of interleukin-1β.
Volume: 27
Issue: 3
Pages: 109284
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Publication
28679669 | J:244187
First Author: Li W
Year: 2017
Journal: Dis Model Mech
Title: A small-molecule TrkB ligand restores hippocampal synaptic plasticity and object location memory in Rett syndrome mice.
Volume: 10
Issue: 7
Pages: 837-845
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Publication
18708129 | J:140968
First Author: Hanstein R
Year: 2008
Journal: Neuroscience
Title: Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress.
Volume: 156
Issue: 3
Pages: 712-21
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Publication
26846222 | J:324498
First Author: Barnstable CJ
Year: 2016
Journal: J Mol Neurosci
Title: Mitochondrial Uncoupling Protein 2 (UCP2) Regulates Retinal Ganglion Cell Number and Survival.
Volume: 58
Issue: 4
Pages: 461-9
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Publication
33606976 | J:303948
First Author: Casarotto PC
Year: 2021
Journal: Cell
Title: Antidepressant drugs act by directly binding to TRKB neurotrophin receptors.
Volume: 184
Issue: 5
Pages: 1299-1313.e19
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Publication
19915139 | J:155587
First Author: Karlén A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Nogo receptor 1 regulates formation of lasting memories.
Volume: 106
Issue: 48
Pages: 20476-81
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Publication
24056302 | J:201817
First Author: Niu W
Year: 2013
Journal: Nat Cell Biol
Title: In vivo reprogramming of astrocytes to neuroblasts in the adult brain.
Volume: 15
Issue: 10
Pages: 1164-75
•
•
•
•
•
Publication
17050730 | J:113400
First Author: Hisatsune C
Year: 2006
Journal: J Neurosci
Title: Inositol 1,4,5-trisphosphate receptor type 1 in granule cells, not in Purkinje cells, regulates the dendritic morphology of Purkinje cells through brain-derived neurotrophic factor production.
Volume: 26
Issue: 42
Pages: 10916-24
•
•
•
•
•
Publication
19429099 | J:150447
First Author: Arai JA
Year: 2009
Journal: Neurosci Lett
Title: Sos2 is dispensable for NMDA-induced Erk activation and LTP induction.
Volume: 455
Issue: 1
Pages: 22-5
•
•
•
•
•
Publication
25916883 | J:259653
 
First Author: Mendez-David I
Year: 2015
Journal: Neurosci Lett
Title: Nrf2-signaling and BDNF: A new target for the antidepressant-like activity of chronic fluoxetine treatment in a mouse model of anxiety/depression.
Volume: 597
Pages: 121-6
•
•
•
•
•
Publication
18809377 | J:142834
First Author: Hayashi A
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Attenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1.
Volume: 376
Issue: 4
Pages: 758-63
•
•
•
•
•
Publication
23746982 | J:199086
First Author: Benraiss A
Year: 2013
Journal: Cell Stem Cell
Title: Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease.
Volume: 12
Issue: 6
Pages: 787-99
•
•
•
•
•
Publication
28467927 | J:271995
First Author: Zhang Y
Year: 2017
Journal: Cell Metab
Title: Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight.
Volume: 25
Issue: 5
Pages: 1091-1102.e4
•
•
•
•
•
Publication
20935641 | J:166927
First Author: Jeanneteau F
Year: 2010
Journal: Nat Neurosci
Title: The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branching.
Volume: 13
Issue: 11
Pages: 1373-9
•
•
•
•
•
Publication
22209255 | J:188314
First Author: Griffioen KJ
Year: 2012
Journal: Neurobiol Aging
Title: Aberrant heart rate and brainstem brain-derived neurotrophic factor (BDNF) signaling in a mouse model of Huntington's disease.
Volume: 33
Issue: 7
Pages: 1481.e1-5
•
•
•
•
•
Publication
35476440 | J:324614
First Author: Bai PY
Year: 2022
Journal: Sci Adv
Title: Environmental eustress improves postinfarction cardiac repair via enhancing cardiac macrophage survival.
Volume: 8
Issue: 17
Pages: eabm3436
•
•
•
•
•
Publication
24991961 | J:224118
First Author: Plotkin JL
Year: 2014
Journal: Neuron
Title: Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease.
Volume: 83
Issue: 1
Pages: 178-88
•
•
•
•
•
Publication
22734669 | J:213976
First Author: Namekata K
Year: 2012
Journal: Genes Cells
Title: Dock3 regulates BDNF-TrkB signaling for neurite outgrowth by forming a ternary complex with Elmo and RhoG.
Volume: 17
Issue: 8
Pages: 688-97
•
•
•
•
•
Publication
31507374 | J:310666
 
First Author: Nguyen HTH
Year: 2019
Journal: Front Mol Neurosci
Title: TrkB Agonist LM22A-4 Increases Oligodendroglial Populations During Myelin Repair in the Corpus Callosum.
Volume: 12
Pages: 205
•
•
•
•
•
Publication
21304518 | J:180352
 
First Author: Harada C
Year: 2011
Journal: Nat Commun
Title: Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration.
Volume: 2
Pages: 189
•
•
•
•
•
Publication
25453757 | J:323536
First Author: Panja D
Year: 2014
Journal: Cell Rep
Title: Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK.
Volume: 9
Issue: 4
Pages: 1430-45
•
•
•
•
•
Publication
16242410 | J:107584
First Author: Kumar A
Year: 2005
Journal: Neuron
Title: Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum.
Volume: 48
Issue: 2
Pages: 303-14
•
•
•
•
•
Publication
28735747 | J:270893
First Author: Vidaki M
Year: 2017
Journal: Neuron
Title: A Requirement for Mena, an Actin Regulator, in Local mRNA Translation in Developing Neurons.
Volume: 95
Issue: 3
Pages: 608-622.e5
•
•
•
•
•
Publication
30687079 | J:276049
 
First Author: You M
Year: 2018
Journal: Front Aging Neurosci
Title: Royal Jelly Alleviates Cognitive Deficits and β-Amyloid Accumulation in APP/PS1 Mouse Model Via Activation of the cAMP/PKA/CREB/BDNF Pathway and Inhibition of Neuronal Apoptosis.
Volume: 10
Pages: 428
•
•
•
•
•
Publication
28593137 | J:310966
First Author: Hunter CJ
Year: 2017
Journal: FEBS Open Bio
Title: MSK1 regulates transcriptional induction of Arc/Arg3.1 in response to neurotrophins.
Volume: 7
Issue: 6
Pages: 821-834
•
•
•
•
•




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