| Type |
Details |
Score |
| Publication |
| First Author: |
Xiao HB |
| Year: |
2011 |
| Journal: |
Toxicol Appl Pharmacol |
| Title: |
Kaempferol regulates OPN-CD44 pathway to inhibit the atherogenesis of apolipoprotein E deficient mice. |
| Volume: |
257 |
| Issue: |
3 |
| Pages: |
405-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang L |
| Year: |
2015 |
| Journal: |
Genes Dev |
| Title: |
ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis. |
| Volume: |
29 |
| Issue: |
2 |
| Pages: |
171-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lakshminarayan R |
| Year: |
2014 |
| Journal: |
Nat Cell Biol |
| Title: |
Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers. |
| Volume: |
16 |
| Issue: |
6 |
| Pages: |
595-606 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
An H |
| Year: |
2015 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Salinomycin possesses anti-tumor activity and inhibits breast cancer stem-like cells via an apoptosis-independent pathway. |
| Volume: |
466 |
| Issue: |
4 |
| Pages: |
696-703 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kurz S |
| Year: |
2017 |
| Journal: |
PLoS One |
| Title: |
The anti-tumorigenic activity of A2M-A lesson from the naked mole-rat. |
| Volume: |
12 |
| Issue: |
12 |
| Pages: |
e0189514 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang H |
| Year: |
2017 |
| Journal: |
Exp Cell Res |
| Title: |
Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow. |
| Volume: |
351 |
| Issue: |
1 |
| Pages: |
91-99 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lazareth H |
| Year: |
2019 |
| Journal: |
Nat Commun |
| Title: |
The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
3303 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
85
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
78
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Barta E |
| Year: |
1993 |
| Journal: |
Biochem J |
| Title: |
Evolution of the hyaluronan-binding module of link protein. |
| Volume: |
292 ( Pt 3) |
|
| Pages: |
947-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kohda D |
| Year: |
1996 |
| Journal: |
Cell |
| Title: |
Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration. |
| Volume: |
86 |
| Issue: |
5 |
| Pages: |
767-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leontieva OV |
| Year: |
2009 |
| Journal: |
Cell Cycle |
| Title: |
RNA-binding motif protein 35A is a novel tumor suppressor for colorectal cancer. |
| Volume: |
8 |
| Issue: |
3 |
| Pages: |
490-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fagoonee S |
| Year: |
2017 |
| Journal: |
Oncotarget |
| Title: |
The RNA-binding protein ESRP1 promotes human colorectal cancer progression. |
| Volume: |
8 |
| Issue: |
6 |
| Pages: |
10007-10024 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
The link domain []is a hyaluronan(HA)-binding region found in proteins of vertebrates that are involved in the assembly of extracellular matrix, cell adhesion, and migration. The structure has been shown []to consist of two alpha helices and two antiparallel beta sheets arranged around a large hydrophobic core similar to that of C-typelectin. This domain contains four conserved cysteines involved in two disulphide bonds. The link domain has also been termed HABM [](HA binding module) and PTR [](proteoglycan tandem repeat). Proteins with such a domain include the proteoglycans aggrecan, brevican, neurocan and versican, which are expressed in the CNS; the cartilage link protein (LP), a proteoglycan that together with HA and aggrecan forms multimolecular aggregates; Tumour necrosis factor-inducible protein TSG-6, which may be involved in cell-cell and cell-matrix interactions during inflammation and tumourgenesis; and CD44 antigen, the main cell surface receptor for HA. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This entry represents the RNA recognition motif 1 (RRM1) of epithelial splicing regulatory protein 1 (ESRP1). ESRP1 has been identified as an epithelial cell type-specific regulator of fibroblast growth factor receptor 2 (FGFR2) splicing []. It is required for expression of epithelial FGFR2-IIIb and the regulation of CD44, CTNND1 (p120-Catenin) and ENAH (hMena) splicing. It enhances epithelial-specific exons of CD44 and ENAH, silences mesenchymal exons of CTNND1, or both within FGFR2 []. ESRP1 has been shown to function as a tumour suppressor in colon cancer cells, due to its ability to bind to the 5' UTR of several cancer-related genes and regulate their translation []. However, high ESRP1 expression has been linked to colorectal cancer progression []. ESRP1 contains three RNA recognition motifs (RRMs). |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
140
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lankes W |
| Year: |
1988 |
| Journal: |
Biochem J |
| Title: |
A heparin-binding protein involved in inhibition of smooth-muscle cell proliferation. |
| Volume: |
251 |
| Issue: |
3 |
| Pages: |
831-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bretscher A |
| Year: |
1983 |
| Journal: |
J Cell Biol |
| Title: |
Purification of an 80,000-dalton protein that is a component of the isolated microvillus cytoskeleton, and its localization in nonmuscle cells. |
| Volume: |
97 |
| Issue: |
2 |
| Pages: |
425-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsukita S |
| Year: |
1989 |
| Journal: |
J Cell Biol |
| Title: |
A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterization. |
| Volume: |
108 |
| Issue: |
6 |
| Pages: |
2369-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Serrador JM |
| Year: |
1997 |
| Journal: |
J Cell Biol |
| Title: |
Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarization. |
| Volume: |
138 |
| Issue: |
6 |
| Pages: |
1409-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Serrador JM |
| Year: |
1998 |
| Journal: |
Blood |
| Title: |
CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts. |
| Volume: |
91 |
| Issue: |
12 |
| Pages: |
4632-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gatto CL |
| Year: |
2007 |
| Journal: |
J Cell Physiol |
| Title: |
Asymmetric ERM activation at the Schwann cell process tip is required in axon-associated motility. |
| Volume: |
210 |
| Issue: |
1 |
| Pages: |
122-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Terawaki S |
| Year: |
2007 |
| Journal: |
J Biol Chem |
| Title: |
Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex. |
| Volume: |
282 |
| Issue: |
27 |
| Pages: |
19854-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Södersten E |
| Year: |
2010 |
| Journal: |
Cell Cycle |
| Title: |
The novel BTB/POZ and zinc finger factor Zbtb45 is essential for proper glial differentiation of neural and oligodendrocyte progenitor cells. |
| Volume: |
9 |
| Issue: |
24 |
| Pages: |
4866-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Posevitz V |
| Year: |
2008 |
| Journal: |
J Immunol |
| Title: |
Regulation of T cell homeostasis by the transmembrane adaptor protein SIT. |
| Volume: |
180 |
| Issue: |
3 |
| Pages: |
1634-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Screaton GR |
| Year: |
1995 |
| Journal: |
EMBO J |
| Title: |
Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. |
| Volume: |
14 |
| Issue: |
17 |
| Pages: |
4336-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li H |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
Kit (W-sh) mice develop earlier and more severe experimental autoimmune encephalomyelitis due to absence of immune suppression. |
| Volume: |
187 |
| Issue: |
1 |
| Pages: |
274-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leong KG |
| Year: |
2008 |
| Journal: |
Nature |
| Title: |
Generation of a prostate from a single adult stem cell. |
| Volume: |
456 |
| Issue: |
7223 |
| Pages: |
804-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gregory GD |
| Year: |
2005 |
| Journal: |
Eur J Immunol |
| Title: |
Mast cells are required for optimal autoreactive T cell responses in a murine model of multiple sclerosis. |
| Volume: |
35 |
| Issue: |
12 |
| Pages: |
3478-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guetta-Terrier C |
| Year: |
2023 |
| Journal: |
Cancer Res |
| Title: |
Chi3l1 Is a Modulator of Glioma Stem Cell States and a Therapeutic Target in Glioblastoma. |
| Volume: |
83 |
| Issue: |
12 |
| Pages: |
1984-1999 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu H |
| Year: |
2010 |
| Journal: |
Carcinogenesis |
| Title: |
Apc(MIN) modulation of vitamin D secosteroid growth control. |
| Volume: |
31 |
| Issue: |
8 |
| Pages: |
1434-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dai H |
| Year: |
2019 |
| Journal: |
Lupus |
| Title: |
Interleukin-23 deficiency alters thymic selection in lupus-prone mice. |
| Volume: |
28 |
| Issue: |
8 |
| Pages: |
1007-1012 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rafi AQ |
| Year: |
1998 |
| Journal: |
J Immunol |
| Title: |
Evidence for the involvement of Fas ligand and perforin in the induction of vascular leak syndrome. |
| Volume: |
161 |
| Issue: |
6 |
| Pages: |
3077-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sad S |
| Year: |
1999 |
| Journal: |
J Immunol |
| Title: |
Cytokine deprivation of naive CD8+ T cells promotes minimal cell cycling but maximal cytokine synthesis and autonomous proliferation subsequently: a mechanism of self-regulation. |
| Volume: |
163 |
| Issue: |
5 |
| Pages: |
2443-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Johnson JL |
| Year: |
2011 |
| Journal: |
Infect Immun |
| Title: |
Increased survival and reduced neutrophil infiltration of the liver in Rab27a- but not Munc13-4-deficient mice in lipopolysaccharide-induced systemic inflammation. |
| Volume: |
79 |
| Issue: |
9 |
| Pages: |
3607-18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Godfrey DI |
| Year: |
1994 |
| Journal: |
J Immunol |
| Title: |
Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. |
| Volume: |
152 |
| Issue: |
10 |
| Pages: |
4783-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Elyaman W |
| Year: |
2008 |
| Journal: |
Am J Pathol |
| Title: |
Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis. |
| Volume: |
173 |
| Issue: |
2 |
| Pages: |
411-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wilson A |
| Year: |
1999 |
| Journal: |
Int Immunol |
| Title: |
Unexpectedly late expression of intracellular CD3epsilon and TCR gammadelta proteins during adult thymus development. |
| Volume: |
11 |
| Issue: |
10 |
| Pages: |
1641-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liang D |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
High level expression of A2ARs is required for the enhancing function, but not for the inhibiting function, of γδ T cells in the autoimmune responses of EAU. |
| Volume: |
13 |
| Issue: |
6 |
| Pages: |
e0199601 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zikmund T |
| Year: |
2019 |
| Journal: |
J Immunol |
| Title: |
ISWI ATPase Smarca5 Regulates Differentiation of Thymocytes Undergoing β-Selection. |
| Volume: |
202 |
| Issue: |
12 |
| Pages: |
3434-3446 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Elewaut D |
| Year: |
2003 |
| Journal: |
J Exp Med |
| Title: |
NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells. |
| Volume: |
197 |
| Issue: |
12 |
| Pages: |
1623-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deng GM |
| Year: |
2013 |
| Journal: |
J Immunol |
| Title: |
T cell CD3ζ deficiency enables multiorgan tissue inflammation. |
| Volume: |
191 |
| Issue: |
7 |
| Pages: |
3563-7 |
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•
•
•
•
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| Publication |
| First Author: |
Pollard KM |
| Year: |
2004 |
| Journal: |
J Immunol |
| Title: |
Costimulation requirements of induced murine systemic autoimmune disease. |
| Volume: |
173 |
| Issue: |
9 |
| Pages: |
5880-7 |
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•
•
•
•
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| Publication |
| First Author: |
Cornish AL |
| Year: |
2003 |
| Journal: |
J Biol Chem |
| Title: |
Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other gamma c-dependent cytokines in peripheral T cells. |
| Volume: |
278 |
| Issue: |
25 |
| Pages: |
22755-61 |
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•
•
•
•
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| Publication |
| First Author: |
Turner J |
| Year: |
2004 |
| Journal: |
Mech Ageing Dev |
| Title: |
The expression of early resistance to an infection with Mycobacterium tuberculosis by old mice is dependent on IFN type II (IFN-gamma) but not IFN type I. |
| Volume: |
125 |
| Issue: |
1 |
| Pages: |
1-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ilangumaran S |
| Year: |
2003 |
| Journal: |
Blood |
| Title: |
Suppressor of cytokine signaling 1 attenuates IL-15 receptor signaling in CD8+ thymocytes. |
| Volume: |
102 |
| Issue: |
12 |
| Pages: |
4115-22 |
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•
•
•
•
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| Publication |
| First Author: |
Bollyky PL |
| Year: |
2011 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors. |
| Volume: |
108 |
| Issue: |
19 |
| Pages: |
7938-43 |
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•
•
•
•
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| Publication |
| First Author: |
Freitas do Rosário AP |
| Year: |
2012 |
| Journal: |
J Immunol |
| Title: |
IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. |
| Volume: |
188 |
| Issue: |
3 |
| Pages: |
1178-90 |
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•
•
•
•
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| Publication |
| First Author: |
Moreira-Teixeira L |
| Year: |
2017 |
| Journal: |
J Immunol |
| Title: |
T Cell-Derived IL-10 Impairs Host Resistance to Mycobacterium tuberculosis Infection. |
| Volume: |
199 |
| Issue: |
2 |
| Pages: |
613-623 |
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•
•
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| Publication |
| First Author: |
Chen J |
| Year: |
2014 |
| Journal: |
BMC Immunol |
| Title: |
Vitamin D receptor expression controls proliferation of naïve CD8+ T cells and development of CD8 mediated gastrointestinal inflammation. |
| Volume: |
15 |
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| Pages: |
6 |
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•
•
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| Publication |
| First Author: |
Yago T |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Core 1-derived O-glycans are essential E-selectin ligands on neutrophils. |
| Volume: |
107 |
| Issue: |
20 |
| Pages: |
9204-9 |
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| Publication |
| First Author: |
Mulay SR |
| Year: |
2017 |
| Journal: |
J Am Soc Nephrol |
| Title: |
Hyperoxaluria Requires TNF Receptors to Initiate Crystal Adhesion and Kidney Stone Disease. |
| Volume: |
28 |
| Issue: |
3 |
| Pages: |
761-768 |
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| First Author: |
Mycko MP |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Selective requirement for c-Myc at an early stage of V(alpha)14i NKT cell development. |
| Volume: |
182 |
| Issue: |
8 |
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4641-8 |
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| First Author: |
Oreff GL |
| Year: |
2023 |
| Journal: |
Sci Rep |
| Title: |
Immortalized murine tenocyte cells: a novel and innovative tool for tendon research. |
| Volume: |
13 |
| Issue: |
1 |
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1566 |
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| First Author: |
Tang J |
| Year: |
2011 |
| Journal: |
Blood |
| Title: |
Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites. |
| Volume: |
118 |
| Issue: |
3 |
| Pages: |
786-94 |
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•
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| First Author: |
Nakano H |
| Year: |
1998 |
| Journal: |
Blood |
| Title: |
A novel mutant gene involved in T-lymphocyte-specific homing into peripheral lymphoid organs on mouse chromosome 4. |
| Volume: |
91 |
| Issue: |
8 |
| Pages: |
2886-95 |
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| First Author: |
Lacerda-Queiroz N |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Phosphatidylinositol 3-Kinase γ is required for the development of experimental cerebral malaria. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
e0119633 |
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•
•
•
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| First Author: |
Piconese S |
| Year: |
2008 |
| Journal: |
J Exp Med |
| Title: |
OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection. |
| Volume: |
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| Issue: |
4 |
| Pages: |
825-39 |
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•
•
•
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| Publication |
| First Author: |
McDonald B |
| Year: |
2013 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Kupffer cells and activation of endothelial TLR4 coordinate neutrophil adhesion within liver sinusoids during endotoxemia. |
| Volume: |
305 |
| Issue: |
11 |
| Pages: |
G797-806 |
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•
•
•
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| Publication |
| First Author: |
Laurent J |
| Year: |
2004 |
| Journal: |
Int Immunol |
| Title: |
New insights into the proliferation and differentiation of early mouse thymocytes. |
| Volume: |
16 |
| Issue: |
8 |
| Pages: |
1069-80 |
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•
•
•
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| First Author: |
Shao B |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
O-glycans direct selectin ligands to lipid rafts on leukocytes. |
| Volume: |
112 |
| Issue: |
28 |
| Pages: |
8661-6 |
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•
•
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| Publication |
| First Author: |
Kuppe C |
| Year: |
2019 |
| Journal: |
Kidney Int |
| Title: |
Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions. |
| Volume: |
96 |
| Issue: |
1 |
| Pages: |
80-93 |
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•
•
•
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| Publication |
| First Author: |
Viret C |
| Year: |
2000 |
| Journal: |
J Immunol |
| Title: |
On the self-referential nature of naive MHC class II-restricted T cells. |
| Volume: |
165 |
| Issue: |
11 |
| Pages: |
6183-92 |
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•
•
•
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| Publication |
| First Author: |
Ochi A |
| Year: |
2017 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
MIF-2/D-DT enhances proximal tubular cell regeneration through SLPI- and ATF4-dependent mechanisms. |
| Volume: |
313 |
| Issue: |
3 |
| Pages: |
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