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Search results 1401 to 1500 out of 1934 for Fos

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Type Details Score
Publication
9074506 | J:38783
First Author: Lecomte F
Year: 1997
Journal: Gene
Title: The S3a ribosomal protein gene is identical to the Fte-1 (v-fos transformation effector) gene and the TNF-alpha-induced TU-11 gene, and its transcript level is altered in transformed and tumor cells.
Volume: 186
Issue: 2
Pages: 271-7
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Publication
25499759 | J:221379
First Author: Fog CK
Year: 2015
Journal: Blood
Title: Loss of PRDM11 promotes MYC-driven lymphomagenesis.
Volume: 125
Issue: 8
Pages: 1272-81
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Publication
19563755 | J:157338
First Author: Wu Q
Year: 2009
Journal: Cell
Title: Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation.
Volume: 137
Issue: 7
Pages: 1225-34
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Publication
28844837 | J:253975
First Author: Li F
Year: 2017
Journal: Cell Stem Cell
Title: Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1.
Volume: 21
Issue: 3
Pages: 359-373.e5
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Publication
30463015 | J:270675
First Author: Wehde BL
Year: 2018
Journal: Cell Rep
Title: Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression.
Volume: 25
Issue: 8
Pages: 2192-2207.e5
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Publication
15128843 | J:96902
First Author: Dai Y
Year: 2004
Journal: J Neurosci
Title: Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain.
Volume: 24
Issue: 18
Pages: 4293-9
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Publication
32385332 | J:295347
First Author: Yu L
Year: 2020
Journal: Nat Commun
Title: Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression.
Volume: 11
Issue: 1
Pages: 2286
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Publication
33150865 | J:298686
   
First Author: Zhang X
Year: 2020
Journal: Elife
Title: MicroRNAs of the miR-17~9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression.
Volume: 9
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Publication
11433347 | J:127006
First Author: Vergnolle N
Year: 2001
Journal: Nat Med
Title: Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway.
Volume: 7
Issue: 7
Pages: 821-6
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Publication
9570795 | J:47453
First Author: Brandon EP
Year: 1998
Journal: J Neurosci
Title: Defective motor behavior and neural gene expression in RIIbeta-protein kinase A mutant mice.
Volume: 18
Issue: 10
Pages: 3639-49
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Publication
33463524 | J:301403
   
First Author: Zhang L
Year: 2021
Journal: Elife
Title: Behavioral role of PACAP signaling reflects its selective distribution in glutamatergic and GABAergic neuronal subpopulations.
Volume: 10
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Publication
23281395 | J:194505
First Author: Yamada K
Year: 2013
Journal: J Clin Invest
Title: EWS/ATF1 expression induces sarcomas from neural crest-derived cells in mice.
Volume: 123
Issue: 2
Pages: 600-10
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Publication
26258633 | J:227279
First Author: Zanconato F
Year: 2015
Journal: Nat Cell Biol
Title: Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth.
Volume: 17
Issue: 9
Pages: 1218-27
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Publication
21482764 | J:171345
First Author: Solway B
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Tonic inhibition of chronic pain by neuropeptide Y.
Volume: 108
Issue: 17
Pages: 7224-9
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Publication
10675797 | J:108024
First Author: Glass JD
Year: 2000
Journal: Neurosci Lett
Title: Polysialylated neural cell adhesion molecule modulates photic signaling in the mouse suprachiasmatic nucleus.
Volume: 280
Issue: 3
Pages: 207-10
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Publication
24411733 | J:220412
First Author: Baldan LC
Year: 2014
Journal: Neuron
Title: Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice.
Volume: 81
Issue: 1
Pages: 77-90
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Publication
20503365 | J:160590
First Author: Rebelo S
Year: 2010
Journal: Dev Dyn
Title: Prrxl1 is required for the generation of a subset of nociceptive glutamatergic superficial spinal dorsal horn neurons.
Volume: 239
Issue: 6
Pages: 1684-94
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Publication
10103106 | J:54156
First Author: Hiroi N
Year: 1999
Journal: Eur J Neurosci
Title: Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice.
Volume: 11
Issue: 3
Pages: 1114-8
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Publication
23620827 | J:200101
First Author: Furutani N
Year: 2013
Journal: PLoS One
Title: Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states.
Volume: 8
Issue: 4
Pages: e62391
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Publication
17335778 | J:120329
First Author: Shiraiwa T
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Involvement of the calcium channel beta3 subunit in olfactory signal transduction.
Volume: 355
Issue: 4
Pages: 1019-24
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Publication
34320411 | J:321732
First Author: Larsen SB
Year: 2021
Journal: Cell Stem Cell
Title: Establishment, maintenance, and recall of inflammatory memory.
Volume: 28
Issue: 10
Pages: 1758-1774.e8
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Publication
15964274 | J:99568
First Author: Sekaran S
Year: 2005
Journal: Curr Biol
Title: Melanopsin-dependent photoreception provides earliest light detection in the mammalian retina.
Volume: 15
Issue: 12
Pages: 1099-107
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Publication
15033178 | J:89353
First Author: Ohtori S
Year: 2004
Journal: Mol Cell Neurosci
Title: Reduced inflammatory pain in mice deficient in the differential screening-selected gene aberrative in neuroblastoma.
Volume: 25
Issue: 3
Pages: 504-14
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Publication
24737889 | J:208834
First Author: Danjo T
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Aversive behavior induced by optogenetic inactivation of ventral tegmental area dopamine neurons is mediated by dopamine D2 receptors in the nucleus accumbens.
Volume: 111
Issue: 17
Pages: 6455-60
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Publication
32514139 | J:298290
First Author: Poll S
Year: 2020
Journal: Nat Neurosci
Title: Memory trace interference impairs recall in a mouse model of Alzheimer's disease.
Volume: 23
Issue: 8
Pages: 952-958
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Publication
38669575 | J:348865
First Author: Tan B
Year: 2024
Journal: Science
Title: Drugs of abuse hijack a mesolimbic pathway that processes homeostatic need.
Volume: 384
Issue: 6693
Pages: eadk6742
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Publication
38266644 | J:346679
First Author: Yang D
Year: 2024
Journal: Neuron
Title: Phosphorylation of pyruvate dehydrogenase inversely associates with neuronal activity.
Volume: 112
Issue: 6
Pages: 959-971.e8
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Publication
33357440 | J:300782
First Author: Rieger MA
Year: 2020
Journal: Cell Rep
Title: CLIP and Massively Parallel Functional Analysis of CELF6 Reveal a Role in Destabilizing Synaptic Gene mRNAs through Interaction with 3' UTR Elements.
Volume: 33
Issue: 12
Pages: 108531
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Publication
24411939 | J:210546
First Author: Yulyaningsih E
Year: 2014
Journal: Cell Metab
Title: Pancreatic polypeptide controls energy homeostasis via Npy6r signaling in the suprachiasmatic nucleus in mice.
Volume: 19
Issue: 1
Pages: 58-72
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Publication
37580379 | J:339095
First Author: Silvério-Alves R
Year: 2023
Journal: Nat Commun
Title: GATA2 mitotic bookmarking is required for definitive haematopoiesis.
Volume: 14
Issue: 1
Pages: 4645
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Publication
7665092 | J:30132
First Author: Davydov IV
Year: 1995
Journal: Gene
Title: Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter.
Volume: 161
Issue: 2
Pages: 271-5
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Publication
11402336 | J:69535
First Author: Jochum W
Year: 2001
Journal: Oncogene
Title: AP-1 in mouse development and tumorigenesis.
Volume: 20
Issue: 19
Pages: 2401-12
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Publication
1729696 | J:19401
First Author: Swaroop A
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: A conserved retina-specific gene encodes a basic motif/leucine zipper domain.
Volume: 89
Issue: 1
Pages: 266-70
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Publication
7701328 | J:24206
First Author: Hu Q
Year: 1995
Journal: Science
Title: Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase.
Volume: 268
Issue: 5207
Pages: 100-2
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Publication
7748560 | J:25501
First Author: Ham J
Year: 1995
Journal: Neuron
Title: A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death.
Volume: 14
Issue: 5
Pages: 927-39
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Publication
8723999 | J:33026
First Author: Foletta VC
Year: 1996
Journal: Immunol Cell Biol
Title: Transcription factor AP-1, and the role of Fra-2.
Volume: 74
Issue: 2
Pages: 121-33
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Publication
8954781 | J:36980
First Author: Molven A
Year: 1996
Journal: Genomics
Title: Chromosomal assignment of the human gene encoding the Fos-related antigen-2 (FRA2) to chromosome 2p22-p23.
Volume: 38
Issue: 1
Pages: 72-5
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Publication
9764823 | J:49887
First Author: McHenry JZ
Year: 1998
Journal: Oncogene
Title: Overexpression of fra-2 in transgenic mice perturbs normal eye development.
Volume: 17
Issue: 9
Pages: 1131-40
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Publication
9808160 | J:52769
First Author: Rupp B
Year: 1998
Journal: Mol Carcinog
Title: Discordant effects of activator protein-1 transcription factor on gene regulation, invasion, and metastasis in spontaneous, radiation-induced, and fos-induced osteosarcomas.
Volume: 23
Issue: 2
Pages: 69-75
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Publication
10349846 | J:55059
First Author: Thomas EA
Year: 1999
Journal: J Neurochem
Title: The endogenous lipid oleamide activates serotonin 5-HT7 neurons in mouse thalamus and hypothalamus.
Volume: 72
Issue: 6
Pages: 2370-8
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Publication
14734719 | J:87651
First Author: Yu XZ
Year: 2004
Journal: J Immunol
Title: Lck is required for activation-induced T cell death after TCR ligation with partial agonists.
Volume: 172
Issue: 3
Pages: 1437-43
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Publication
16785536 | J:134401
First Author: Nandiwada SL
Year: 2006
Journal: J Immunol
Title: p300/Cyclic AMP-responsive element binding-binding protein mediates transcriptional coactivation by the CD28 T cell costimulatory receptor.
Volume: 177
Issue: 1
Pages: 401-13
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Publication
7889406 | J:189427
First Author: Choi MS
Year: 1994
Journal: Immunity
Title: Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4.
Volume: 1
Issue: 3
Pages: 179-87
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Publication
23023294 | J:285977
First Author: Koya E
Year: 2012
Journal: Nat Neurosci
Title: Silent synapses in selectively activated nucleus accumbens neurons following cocaine sensitization.
Volume: 15
Issue: 11
Pages: 1556-62
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Publication
30063946 | J:273322
 
First Author: Levi NJ
Year: 2018
Journal: Mol Cell Endocrinol
Title: Obesity-related cellular stressors regulate gonadotropin releasing hormone gene expression via c-Fos/AP-1.
Volume: 478
Pages: 97-105
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Publication
31170673 | J:295512
 
First Author: Murayama S
Year: 2019
Journal: J Neuroimmunol
Title: Activation of microglia and macrophages in the circumventricular organs of the mouse brain during TLR2-induced fever and sickness responses.
Volume: 334
Pages: 576973
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Publication
32848052 | J:298802
First Author: Hirose Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Hypnotic effect of thalidomide is independent of teratogenic ubiquitin/proteasome pathway.
Volume: 117
Issue: 37
Pages: 23106-23112
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Publication
27159561 | J:331732
First Author: Devaiah BN
Year: 2016
Journal: Nat Struct Mol Biol
Title: BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin.
Volume: 23
Issue: 6
Pages: 540-8
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Protein
Q1LZK3
Organism: Mus musculus/domesticus
Length: 54  
Fragment?: false
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Protein
A0A1Y7VLU6
Organism: Mus musculus/domesticus
Length: 42  
Fragment?: true
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Protein
Q3U0S8
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Publication
22464321 | -
First Author: Dang CV
Year: 2012
Journal: Cell
Title: MYC on the path to cancer.
Volume: 149
Issue: 1
Pages: 22-35
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Publication
1696724 | -
First Author: Zhang K
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: Drosophila homolog of the mammalian jun oncogene is expressed during embryonic development and activates transcription in mammalian cells.
Volume: 87
Issue: 16
Pages: 6281-5
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Publication
2116361 | -
First Author: Perkins KK
Year: 1990
Journal: Genes Dev
Title: The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor.
Volume: 4
Issue: 5
Pages: 822-34
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Publication
9224723 | -
First Author: Kockel L
Year: 1997
Journal: Genes Dev
Title: Jun in Drosophila development: redundant and nonredundant functions and regulation by two MAPK signal transduction pathways.
Volume: 11
Issue: 13
Pages: 1748-58
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Protein Domain
IPR015558 | C_Jun/v-Jun
Type: Family
Description: Transcription factor c-Jun (also known as transcription factor AP-1) is a member of the transcription factor activator protein (AP)-1 family, comprising Jun (c-Jun, JunB, and JunD), Fos (c-Fos, FosB, Fra1, and Fra2), ATF (ATFa, ATF-2 and ATF-3) and JDP (JDP-1 and JDP-2) family members []. They are basic leucine zipper transcription factors that play a central role in regulating gene transcription in various biological processes []. c-Jun was originally identified as the normal cellular counterpart of the viral Jun oncoprotein (v-Jun) encoded by an avian sarcoma virus (ASV17). The 39kDa c-Jun protein consists of a C-terminal basic region-leucine zipper (B-ZIP) DNA-binding domain and a N-terminal transcriptional activation domain.AP-1 proteins have a α-helical bZIP domain, which contains a basic DNA-binding region and regularly spaced leucine residues known as the leucine zipper motif []. They have similar protein structure and can either form homodimers or form heterodimers with other AP-1 proteins (predominantly with Jun proteins), which can then bind to TRE-like sequences (consensus sequence 5'-TGAG/CTCA-3') []. Each of these proteins are expressed in different tissues and can be regulated in different ways, which means that every cell type has a complex mixture of AP-1 dimers with subtly different functions [].
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Protein Domain
IPR029823 | JunD
Type: Family
Description: Transcription factor JunD is a member of the transcription factor activator protein (AP)-1 family, comprising Jun (c-Jun, JunB, and JunD), Fos (c-Fos, FosB, Fra1, and Fra2), ATF (ATFa, ATF-2 and ATF-3) and JDP (JDP-1 and JDP-2) family members []. They are basic leucine zipper transcription factors that play a central role in regulating gene transcription in various biological processes []. This entry also includes transcription factor AP-1 (Jra) from Drosophila, which recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' and has a role in dorsal closure [, , ].AP-1 proteins have a α-helical bZIP domain, which contains a basic DNA-binding region and regularly spaced leucine residues known as the leucine zipper motif []. They have similar protein structure and can either form homodimers or form heterodimers with other AP-1 proteins (predominantly with Jun proteins), which can then bind to TRE-like sequences (consensus sequence 5'-TGAG/CTCA-3') []. Each of these proteins are expressed in different tissues and can be regulated in different ways, which means that every cell type has a complex mixture of AP-1 dimers with subtly different functions [].
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Protein Domain
IPR002418 | Tscrpt_reg_Myc
Type: Family
Description: The class III basic helix-turn-helix (bHLH) transcription factors have proliferative and apoptotic roles and are characterised by the presence of a leucine zipper adjacent to the bHLH domain. The myc oncogene was first discovered in small-cell lung cancer cell lines where it is found to be deregulated []. The Myc protein contains an N-terminal transcriptional regulatory domain followed by a nuclear localization signal and a C-terminal basic DNA binding domain tethered to a helix-loop-helix-leucine zipper (HLH-Zip) dimerization motif. Myc forms a heterodimer with Max, and this complex regulates cell growth through direct activation of genes involved in cell replication [, , ].The `leucine zipper' is a structure that is believed to mediate the function of several eukaryotic gene regulatory proteins. The zipper consists of a periodic repetition of leucine residues at every seventh position, and regions containing them appear to span eight turns of α-helix. The leucine side chains that extend from one helix interact with those from a similar helix, hence facilitating dimerisation in the form of a coiled-coil. Leucine zippers are present in many gene regulatory proteins, including the CREB proteins, Jun/AP1 transcription factors, fos oncogene and fos-related proteins, C-myc, L-myc and N-myc oncogenes, and so on.
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Protein
Q6P8Z1
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: false
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Publication
1847666 | J:18605
First Author: Foulkes NS
Year: 1991
Journal: Cell
Title: CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription.
Volume: 64
Issue: 4
Pages: 739-49
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Protein
A0PJL6
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: false
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Publication
2141384 | -
First Author: Quinn PG
Year: 1990
Journal: Mol Cell Biol
Title: Cyclic AMP-dependent protein kinase regulates transcription of the phosphoenolpyruvate carboxykinase gene but not binding of nuclear factors to the cyclic AMP regulatory element.
Volume: 10
Issue: 7
Pages: 3357-64
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Publication
2827002 | -
First Author: Kaye F
Year: 1988
Journal: Mol Cell Biol
Title: Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.
Volume: 8
Issue: 1
Pages: 186-95
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Publication
9175477 | -
First Author: Grandori C
Year: 1997
Journal: Trends Biochem Sci
Title: Myc target genes.
Volume: 22
Issue: 5
Pages: 177-81
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Publication
3018999 | -
First Author: Stewart MA
Year: 1986
Journal: Virology
Title: Conservation of the c-myc coding sequence in transduced feline v-myc genes.
Volume: 154
Issue: 1
Pages: 121-34
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Protein Domain
IPR001630 | Leuzip_CREB
Type: Family
Description: Transcription initiation is dictated by the presence and activity of specific nuclear factors that bind to DNA regulatory sequences and interact with the transcriptional machinery. The functions of some of these factors can be altered by phosphorylation, which affects both DNA binding and transcriptional activation []. Phosphorylation is effected by specific protein kinases that have been activated by the stimulus of signal transduction pathways, resulting in the regulation of gene transcription by modulating the phosphorylation sites of transcription factors.Cyclic AMP (cAMP) regulates the expression of many genes via a conserved gene promoter element CRE (cAMP response element) [], which has the sequence 5'-TGACGTCA-3' []. The cAMP response element binding protein (CREB) is a nuclear factor that is regulated by protein kinase A phosphorylation. Transcription is stimulated on binding to the CRE of a phosphorylated CREB dimer, which is held together by leucine zippers. Dimerisation and transcriptional efficacy have been found to be stimulated by phosphorylation at several distinct sites, and it has thus been suggested []that CREB may be regulated by multiple kinases. Sequence analysis of the gene has revealed a cluster of protein kinase A, protein kinase C, and casein kinase II consensus recognition sites near the N terminus of the protein sequence, and the proximity of these sites to one another indicates the possibility of interaction in a positive or negative fashion to regulate CREB bioactivity.The 'leucine zipper' is a structure that is believed to mediate the function of several eukaryotic gene regulatory proteins. The zipper consists of a periodic repetition of leucine residues at every seventh position, and regions containing them appear to span 8 turns of α-helix. The leucine side chains that extend from one helix interact with those from a similar helix, hence facilitating dimerisation in the form of a coiled-coil. Leucine zippers are present in many gene regulatory proteins, including the CREB proteins, Jun/AP1 transcription factors, fos oncogene and fos-related proteins, C-myc, L-myc and N-myc oncogenes, and so on.
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Publication
17855428 | J:128378
First Author: Kim BM
Year: 2007
Journal: Development
Title: Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen.
Volume: 134
Issue: 20
Pages: 3603-13
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Publication
18575602 | J:137163
First Author: Hadjantonakis AK
Year: 2008
Journal: PLoS One
Title: Tbx6 regulates left/right patterning in mouse embryos through effects on nodal cilia and perinodal signaling.
Volume: 3
Issue: 6
Pages: e2511
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Publication
25249463 | J:217500
First Author: Cui CY
Year: 2014
Journal: Development
Title: Involvement of Wnt, Eda and Shh at defined stages of sweat gland development.
Volume: 141
Issue: 19
Pages: 3752-60
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Publication
22451941 | J:183539
First Author: Voutilainen M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.
Volume: 109
Issue: 15
Pages: 5744-9
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Publication
27765763 | J:237425
First Author: Danopoulos S
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Rac1 modulates mammalian lung branching morphogenesis in part through canonical Wnt signaling.
Volume: 311
Issue: 6
Pages: L1036-L1049
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Publication
24590292 | J:209623
First Author: Kurosaka H
Year: 2014
Journal: J Clin Invest
Title: Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis.
Volume: 124
Issue: 4
Pages: 1660-71
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Publication
28747340 | J:251373
First Author: Bradford EM
Year: 2017
Journal: J Immunol
Title: Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease.
Volume: 199
Issue: 5
Pages: 1886-1897
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Publication
22771246 | J:187621
First Author: van Amerongen R
Year: 2012
Journal: Dev Biol
Title: Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development.
Volume: 369
Issue: 1
Pages: 101-14
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Publication
21316585 | J:169766
First Author: Gao B
Year: 2011
Journal: Dev Cell
Title: Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2.
Volume: 20
Issue: 2
Pages: 163-76
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Publication
26858454 | J:230491
First Author: Hathaway CK
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: High Elmo1 expression aggravates and low Elmo1 expression prevents diabetic nephropathy.
Volume: 113
Issue: 8
Pages: 2218-22
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Publication
34163008 | J:325389
First Author: Kakoki M
Year: 2021
Journal: Commun Biol
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