| Type |
Details |
Score |
| Publication |
| First Author: |
Zaman V |
| Year: |
2008 |
| Journal: |
Eur J Neurosci |
| Title: |
The nigrostriatal dopamine system of aging GFRalpha-1 heterozygous mice: neurochemistry, morphology and behavior. |
| Volume: |
28 |
| Issue: |
8 |
| Pages: |
1557-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Khan SS |
| Year: |
2021 |
| Journal: |
Elife |
| Title: |
Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain. |
| Volume: |
10 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Unezaki S |
| Year: |
2009 |
| Journal: |
J Neurosci Methods |
| Title: |
Effects of neurotrophic factors on nerve regeneration monitored by in vivo imaging in thy1-YFP transgenic mice. |
| Volume: |
178 |
| Issue: |
2 |
| Pages: |
308-15 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Yu CT |
| Year: |
2012 |
| Journal: |
Development |
| Title: |
COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival. |
| Volume: |
139 |
| Issue: |
13 |
| Pages: |
2330-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suriben R |
| Year: |
2020 |
| Journal: |
Nat Med |
| Title: |
Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice. |
| Volume: |
26 |
| Issue: |
8 |
| Pages: |
1264-1270 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Kowsky S |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
RET signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals. |
| Volume: |
104 |
| Issue: |
50 |
| Pages: |
20049-54 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Kalus I |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions. |
| Volume: |
10 |
| Issue: |
10 |
| Pages: |
e0139853 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Nikopoulos GN |
| Year: |
2009 |
| Journal: |
Mech Dev |
| Title: |
NRAGE: a potential rheostat during branching morphogenesis. |
| Volume: |
126 |
| Issue: |
5-6 |
| Pages: |
337-49 |
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•
•
•
•
•
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| Publication |
| First Author: |
Stanga S |
| Year: |
2016 |
| Journal: |
FASEB J |
| Title: |
APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation. |
| Volume: |
30 |
| Issue: |
5 |
| Pages: |
1696-711 |
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•
•
•
•
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| First Author: |
Sunardi M |
| Year: |
2021 |
| Journal: |
Dev Growth Differ |
| Title: |
Live visualization of a functional RET-EGFP chimeric receptor in homozygous knock-in mice. |
| Volume: |
63 |
| Issue: |
6 |
| Pages: |
285-294 |
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•
•
•
•
•
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| Publication |
| First Author: |
Dong A |
| Year: |
2007 |
| Journal: |
J Neurochem |
| Title: |
Increased expression of glial cell line-derived neurotrophic factor protects against oxidative damage-induced retinal degeneration. |
| Volume: |
103 |
| Issue: |
3 |
| Pages: |
1041-52 |
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•
•
•
•
•
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| Publication |
| First Author: |
Yan Y |
| Year: |
2011 |
| Journal: |
Exp Neurol |
| Title: |
Evaluation of peripheral nerve regeneration via in vivo serial transcutaneous imaging using transgenic Thy1-YFP mice. |
| Volume: |
232 |
| Issue: |
1 |
| Pages: |
7-14 |
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•
•
•
•
•
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| Publication |
| First Author: |
De Vincenti AP |
| Year: |
2021 |
| Journal: |
Development |
| Title: |
Lrig1 and Lrig3 cooperate to control Ret receptor signaling, sensory axonal growth and epidermal innervation. |
| Volume: |
148 |
| Issue: |
16 |
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•
•
•
•
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| First Author: |
Jmaeff S |
| Year: |
2020 |
| Journal: |
J Biol Chem |
| Title: |
Small-molecule agonists of the RET receptor tyrosine kinase activate biased trophic signals that are influenced by the presence of GFRa1 co-receptors. |
| Volume: |
295 |
| Issue: |
19 |
| Pages: |
6532-6542 |
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•
•
•
•
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| Publication |
| First Author: |
Fan Y |
| Year: |
2008 |
| Journal: |
Neurobiol Aging |
| Title: |
Hypersensitivity of aquaporin 4-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine and astrocytic modulation. |
| Volume: |
29 |
| Issue: |
8 |
| Pages: |
1226-36 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Li HL |
| Year: |
2006 |
| Journal: |
FEBS Lett |
| Title: |
The novel neurotrophin-regulated neuronal development-associated protein, NDAP, mediates apoptosis. |
| Volume: |
580 |
| Issue: |
7 |
| Pages: |
1723-8 |
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•
•
•
•
•
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| Publication |
| First Author: |
Gao X |
| Year: |
2005 |
| Journal: |
Development |
| Title: |
Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa. |
| Volume: |
132 |
| Issue: |
24 |
| Pages: |
5437-49 |
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•
•
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| First Author: |
Anders J |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Molecular modeling of the extracellular domain of the RET receptor tyrosine kinase reveals multiple cadherin-like domains and a calcium-binding site. |
| Volume: |
276 |
| Issue: |
38 |
| Pages: |
35808-17 |
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•
•
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| First Author: |
Ogilvie JM |
| Year: |
2000 |
| Journal: |
Exp Neurol |
| Title: |
Growth factors in combination, but not individually, rescue rd mouse photoreceptors in organ culture. |
| Volume: |
161 |
| Issue: |
2 |
| Pages: |
676-85 |
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•
•
•
•
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| First Author: |
Oppenheim RW |
| Year: |
2000 |
| Journal: |
J Neurosci |
| Title: |
Glial cell line-derived neurotrophic factor and developing mammalian motoneurons: regulation of programmed cell death among motoneuron subtypes. |
| Volume: |
20 |
| Issue: |
13 |
| Pages: |
5001-11 |
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•
•
•
•
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| First Author: |
Bensadoun JC |
| Year: |
2000 |
| Journal: |
Exp Neurol |
| Title: |
Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF. |
| Volume: |
164 |
| Issue: |
1 |
| Pages: |
15-24 |
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•
•
•
•
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| First Author: |
Masure S |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
Mammalian GFRalpha -4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin. |
| Volume: |
275 |
| Issue: |
50 |
| Pages: |
39427-34 |
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| First Author: |
Suvanto P |
| Year: |
1997 |
| Journal: |
Hum Mol Genet |
| Title: |
Cloning, mRNA distribution and chromosomal localisation of the gene for glial cell line-derived neurotrophic factor receptor beta, a homologue to GDNFR-alpha. |
| Volume: |
6 |
| Issue: |
8 |
| Pages: |
1267-73 |
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| First Author: |
Ho A |
| Year: |
1997 |
| Journal: |
Exp Neurol |
| Title: |
Regulation of astroglial-derived dopaminergic neurotrophic factors by interleukin-1 beta in the striatum of young and middle-aged mice. |
| Volume: |
148 |
| Issue: |
1 |
| Pages: |
348-59 |
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| First Author: |
Angrist M |
| Year: |
1998 |
| Journal: |
Genomics |
| Title: |
Human GFRA1: cloning, mapping, genomic structure, and evaluation as a candidate gene for Hirschsprung disease susceptibility. |
| Volume: |
48 |
| Issue: |
3 |
| Pages: |
354-62 |
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•
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| First Author: |
Golden JP |
| Year: |
1998 |
| Journal: |
J Comp Neurol |
| Title: |
Expression of neurturin, GDNF, and their receptors in the adult mouse CNS. |
| Volume: |
398 |
| Issue: |
1 |
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139-50 |
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•
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| First Author: |
Sariola H |
| Year: |
2003 |
| Journal: |
APMIS |
| Title: |
GDNF-induced seminomatous tumours in mouse--an experimental model for human seminomas? |
| Volume: |
111 |
| Issue: |
1 |
| Pages: |
192-6; discussion 196 |
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| First Author: |
Young HM |
| Year: |
2005 |
| Journal: |
Cell Tissue Res |
| Title: |
The location and phenotype of proliferating neural-crest-derived cells in the developing mouse gut. |
| Volume: |
320 |
| Issue: |
1 |
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1-9 |
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| First Author: |
Costantini F |
| Year: |
2006 |
| Journal: |
Differentiation |
| Title: |
Renal branching morphogenesis: concepts, questions, and recent advances. |
| Volume: |
74 |
| Issue: |
7 |
| Pages: |
402-21 |
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| First Author: |
Hamra FK |
| Year: |
2007 |
| Journal: |
J Biol Chem |
| Title: |
Identification of neuregulin as a factor required for formation of aligned spermatogonia. |
| Volume: |
282 |
| Issue: |
1 |
| Pages: |
721-30 |
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| First Author: |
Meng X |
| Year: |
2001 |
| Journal: |
Mol Cell Endocrinol |
| Title: |
Transient disruption of spermatogenesis by deregulated expression of neurturin in testis. |
| Volume: |
184 |
| Issue: |
1-2 |
| Pages: |
33-9 |
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| First Author: |
Ledda F |
| Year: |
2008 |
| Journal: |
J Neurosci |
| Title: |
Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF. |
| Volume: |
28 |
| Issue: |
1 |
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39-49 |
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| First Author: |
Lee J |
| Year: |
2007 |
| Journal: |
Development |
| Title: |
Akt mediates self-renewal division of mouse spermatogonial stem cells. |
| Volume: |
134 |
| Issue: |
10 |
| Pages: |
1853-9 |
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| First Author: |
Wu X |
| Year: |
2010 |
| Journal: |
Biol Reprod |
| Title: |
The POU domain transcription factor POU3F1 is an important intrinsic regulator of GDNF-induced survival and self-renewal of mouse spermatogonial stem cells. |
| Volume: |
82 |
| Issue: |
6 |
| Pages: |
1103-11 |
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| First Author: |
Ishii K |
| Year: |
2012 |
| Journal: |
Development |
| Title: |
FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation. |
| Volume: |
139 |
| Issue: |
10 |
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1734-43 |
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| First Author: |
Lippoldt EK |
| Year: |
2013 |
| Journal: |
J Neurosci |
| Title: |
Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold pain. |
| Volume: |
33 |
| Issue: |
30 |
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He S |
| Year: |
2014 |
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Proc Natl Acad Sci U S A |
| Title: |
GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling. |
| Volume: |
111 |
| Issue: |
19 |
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E2008-17 |
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| First Author: |
Wong LE |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Artemin promotes functional long-distance axonal regeneration to the brainstem after dorsal root crush. |
| Volume: |
112 |
| Issue: |
19 |
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6170-5 |
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Schriemer D |
| Year: |
2016 |
| Journal: |
Dev Biol |
| Title: |
Regulators of gene expression in Enteric Neural Crest Cells are putative Hirschsprung disease genes. |
| Volume: |
416 |
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1 |
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255-265 |
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Pui HP |
| Year: |
2017 |
| Journal: |
Mech Dev |
| Title: |
Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. |
| Volume: |
144 |
| Issue: |
Pt B |
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125-139 |
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Schwenkgrub J |
| Year: |
2017 |
| Journal: |
PLoS One |
| Title: |
The phosphodiesterase inhibitor, ibudilast, attenuates neuroinflammation in the MPTP model of Parkinson's disease. |
| Volume: |
12 |
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7 |
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e0182019 |
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Di G |
| Year: |
2017 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Corneal Epithelium-Derived Neurotrophic Factors Promote Nerve Regeneration. |
| Volume: |
58 |
| Issue: |
11 |
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Hermann DM |
| Year: |
2015 |
| Journal: |
Neurobiol Dis |
| Title: |
Sustained neurological recovery induced by resveratrol is associated with angioneurogenesis rather than neuroprotection after focal cerebral ischemia. |
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83 |
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Ko KR |
| Year: |
2018 |
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Sci Rep |
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Hepatocyte Growth Factor (HGF) Promotes Peripheral Nerve Regeneration by Activating Repair Schwann Cells. |
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Pieraccioli M |
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2018 |
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Proc Natl Acad Sci U S A |
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ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma. |
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115 |
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Jankowski MP |
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2018 |
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Neuroscience |
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Increased Expression of Transcription Factor SRY-box-Containing Gene 11 (Sox11) Enhances Neurite Growth by Regulating Neurotrophic Factor Responsiveness. |
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382 |
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Khasnavis S |
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J Biol Chem |
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Castration induces Parkinson disease pathologies in young male mice via inducible nitric-oxide synthase. |
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2013 |
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Cell Death Dis |
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Rad54 is required for the normal development of male and female germ cells and contributes to the maintainance of their genome integrity after genotoxic stress. |
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2018 |
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J Comp Neurol |
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Characterization of retinal ganglion cell, horizontal cell, and amacrine cell types expressing the neurotrophic receptor tyrosine kinase Ret. |
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Nature |
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Neuro-mesenchymal units control ILC2 and obesity via a brain-adipose circuit. |
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2024 |
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Pancreatic Schwann cell reprogramming supports cancer-associated neuronal remodeling. |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1115
 |
| Fragment?: |
false |
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Mouse Genome Informatics Scientific Curators |
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MGI Direct Data Submission |
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Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
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