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Search results 1401 to 1500 out of 1506 for Itgb1

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Type Details Score
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342609
       
First Author: UniProt
Year: 2021
Title: Electronic Gene Ontology annotations created by ARBA machine learning models
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:389486
     
First Author: Mouse Genome Informatics and Ensembl Genome Database Project
Year: 2026
Journal: Database Release
Title: MGI Strain Genome Feature and Gene Model Load from Ensembl.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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GXD Expression
GXD Expression
 
Probe: MGI:6197250
Assay Type: Immunohistochemistry
Annotation Date: 2018-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6197274
Age: embryonic day 11.5
Note: Co-localized with Itgb1 in neuroepithelial cells.
Specimen Label: S6
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5695640
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7431102
Age: postnatal adult
Image: 2C (right)
Note: Expression co-localized with Itgb1 in costamere at sarcolemmal membrane.
Specimen Label: 2C (right)
Detected: true
Specimen Num: 6
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Allele
Itgb1<em2(ITGB1)Smoc> | MGI:7290609
Name: integrin beta 1 (fibronectin receptor beta); endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:7623409 | C57BL/6JSmoc-Itgb1<em2(ITGB1)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Itgb1<tm3Ref> | MGI:2154539
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 3, Reinhard Fassler
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Itgb1<tm1.1Efu> | MGI:3639561
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 1.1, Elaine Fuchs
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Itgb1<tm1Smoc> | MGI:7290610
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Itgb1/Itgb1
Background: involves: 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:6429017 | C57BL/6JSmoc-Itgb1<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Itgb1/Itgb1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Protein
A0A0N4SUW0
Organism: Mus musculus/domesticus
Length: 88  
Fragment?: true
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Protein
A0A0N4SVJ6
Organism: Mus musculus/domesticus
Length: 490  
Fragment?: false
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Protein
Q3TQB4
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Protein
Q8C4E7
Organism: Mus musculus/domesticus
Length: 528  
Fragment?: true
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Protein Domain
IPR022709 | SCAI
Type: Family
Description: SCAI is a transcriptional cofactor and tumour suppressor that suppresses MKL1/MRTFA-induced SRF transcriptional activity. It may function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1 [].
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Protein
Q8C8N2
Organism: Mus musculus/domesticus
Length: 606  
Fragment?: false
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Allele
Itgb1<tm5.1Ref> | MGI:3848527
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 5.1, Reinhard Fassler
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Itgb1/Itgb1
Background: involves: 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
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Protein Domain
IPR016607 | SCAI_metazoan/Viridiplantae
Type: Family
Description: This entry represents protein SCAI from metazoans and plants. SCAI is a transcriptional cofactor and tumour suppressor that suppresses MKL1-induced SRF transcriptional activity. It may function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1 [].
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Allele
Itgb3<tm2Aja> | MGI:3844537
 
Name: integrin beta 3; targeted mutation 2, Ararat J Ablooglu
Allele Type: Targeted
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Genotype
Genotype
Symbol: Itgb1/Itgb1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Itgb3/Itgb3
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Itgb1/Itgb1 Tg(Ttr-cre)1Hadj/?
Background: involves: 129X1/SvJ * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Publication
19350017 | J:150313
First Author: Brandt DT
Year: 2009
Journal: Nat Cell Biol
Title: SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.
Volume: 11
Issue: 5
Pages: 557-68
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Publication
23354167 | J:195219
First Author: Chou J
Year: 2013
Journal: Nat Cell Biol
Title: GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.
Volume: 15
Issue: 2
Pages: 201-13
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Publication
27501152 | J:236616
First Author: K?ffer A
Year: 2016
Journal: Nature
Title: The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6.
Volume: 536
Issue: 7617
Pages: 464-8
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Publication
15189448 | J:100166
First Author: Moriguchi T
Year: 2004
Journal: Genes Cells
Title: DREG, a developmentally regulated G protein-coupled receptor containing two conserved proteolytic cleavage sites.
Volume: 9
Issue: 6
Pages: 549-60
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Publication
25217645 | J:218807
First Author: Cui H
Year: 2014
Journal: J Biol Chem
Title: GPR126 protein regulates developmental and pathological angiogenesis through modulation of VEGFR2 receptor signaling.
Volume: 289
Issue: 50
Pages: 34871-85
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Publication
25695270 | J:219865
First Author: Petersen SC
Year: 2015
Journal: Neuron
Title: The adhesion GPCR GPR126 has distinct, domain-dependent functions in Schwann cell development mediated by interaction with laminin-211.
Volume: 85
Issue: 4
Pages: 755-69
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Publication
25954032 | J:224002
First Author: Karner CM
Year: 2015
Journal: Hum Mol Genet
Title: Gpr126/Adgrg6 deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice.
Volume: 24
Issue: 15
Pages: 4365-73
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Publication
32219165 | J:287435
First Author: Sun P
Year: 2020
Journal: Sci Adv
Title: Regulation of body length and bone mass by Gpr126/Adgrg6.
Volume: 6
Issue: 12
Pages: eaaz0368
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Publication
34767447 | J:315981
First Author: Torregrosa-Carri?n R
Year: 2021
Journal: Sci Adv
Title: Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development.
Volume: 7
Issue: 46
Pages: eabj5445
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Protein
D3Z4E1
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: false
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Protein
Q3ZAX9
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false
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Publication
1974228 | -
First Author: Kimmel BE
Year: 1990
Journal: Genes Dev
Title: The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype.
Volume: 4
Issue: 5
Pages: 712-27
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Publication
33375038 | -
 
First Author: Pa?o A
Year: 2020
Journal: Cancers (Basel)
Title: Roles of the HOX Proteins in Cancer Invasion and Metastasis.
Volume: 13
Issue: 1
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Publication
27144914 | -
First Author: Vogel M
Year: 2016
Journal: Am J Med Genet A
Title: Homozygous HOXB1 loss-of-function mutation in a large family with hereditary congenital facial paresis.
Volume: 170
Issue: 7
Pages: 1813-9
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Publication
32804075 | J:302497
   
First Author: Stefanovic S
Year: 2020
Journal: Elife
Title: Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation.
Volume: 9
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Publication
26284287 | J:226322
First Author: Roux M
Year: 2015
Journal: Dev Biol
Title: Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development.
Volume: 406
Issue: 2
Pages: 247-58
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Publication
27956219 | J:240035
 
First Author: Roux M
Year: 2017
Journal: Mech Dev
Title: Hoxa1 and Hoxb1 are required for pharyngeal arch artery development.
Volume: 143
Pages: 1-8
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Publication
26565624 | -
First Author: Han L
Year: 2015
Journal: PLoS One
Title: HOXB1 Is a Tumor Suppressor Gene Regulated by miR-3175 in Glioma.
Volume: 10
Issue: 11
Pages: e0142387
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Publication
30134070 | J:264530
First Author: Zaffran S
Year: 2018
Journal: Genesis
Title: Ectopic expression of Hoxb1 induces cardiac and craniofacial malformations.
Volume: 56
Issue: 6-7
Pages: e23221
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Publication
16155570 | -
First Author: Tischfield MA
Year: 2005
Journal: Nat Genet
Title: Homozygous HOXA1 mutations disrupt human brainstem, inner ear, cardiovascular and cognitive development.
Volume: 37
Issue: 10
Pages: 1035-7
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Publication
21501586 | -
First Author: Park H
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Homeobox D1 regulates angiogenic functions of endothelial cells via integrin ?1 expression.
Volume: 408
Issue: 1
Pages: 186-92
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Publication
18412118 | -
First Author: Bosley TM
Year: 2008
Journal: Am J Med Genet A
Title: The clinical spectrum of homozygous HOXA1 mutations.
Volume: 146A
Issue: 10
Pages: 1235-40
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Publication
31924782 | -
First Author: Leon K
Year: 2020
Journal: Nat Commun
Title: Structural basis for adhesion G protein-coupled receptor Gpr126 function.
Volume: 11
Issue: 1
Pages: 194
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Protein Domain
IPR046327 | HXA1/B1/D1
Type: Family
Description: This entry represents a group of homeobox proteins, including HOX-A1/B1/D1 (HXA1/B1/D1) and related proteins from animals. The homeobox domain is a DNA binding domain.Human HOX genes are critical for development of the central nervous system []. They have been also implicated in vascular development and angiogenesis, particularly with regulation of genes involved in cell-cell or cell-extracellular matrix (ECM) interactions []. HXA1 has been linked to the Bosley-Salih-Alorainy syndrome (BSAS) or the Athabascan brainstem dysgenesis syndrome (ABDS) []. HXB1 is a transcription factor that play important roles in early vertebrate development [, , , , ]and its expression is associated with tumours [, ]. HOXD1 plays a significant role in endothelial cell functions by regulating the expression of ITGB1 [].Homeobox protein rough from Drosophila melanogaster is a member of this group of proteins. It is required to establish the unique cell identity of photoreceptors R2 and R5 and consequently for ommatidial assembly in the developing eye imaginal disk in the organism [, ].
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Protein Domain
IPR057333 | SEA_Gpr126
Type: Domain
Description: This entry represents the Sperm protein, Enterokinase and Agrin (SEA) domain found in the adhesion G protein-coupled receptor Gpr126/ADGRG6 from vertebrates. The domain adopts a ferredoxin-like ��/�� sandwich fold []and is located between the PTX and HormR domains in the extracellular region. In human GPR126, this domain contains a furin cleavage site that is conserved in many mammals and birds []. After cleavage, the domain remains intact until mechanical force causes separation, similar to SEA domains in other proteins like Mucins and Notch. The SEA domain plays a role in regulating receptor function through proteolytic processing and mechanical force sensing.The mouse member is involved in many biological processes, such as myelination, sprouting angiogenesis, placenta, ear and cartilage development [, , , , ]. It also acts as a regulator of body length and bone mass []and as a regulator of blood-brain barrier formation in the central nervous system via its association with LRP1 and ITGB1 [].
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Publication
19005179 | J:148306
First Author: Ablooglu AJ
Year: 2009
Journal: Blood
Title: Antithrombotic effects of targeting alphaIIbbeta3 signaling in platelets.
Volume: 113
Issue: 15
Pages: 3585-92
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Publication
25587038 | J:221917
First Author: Liao Z
Year: 2015
Journal: Blood
Title: Interaction of kindlin-2 with integrin ?3 promotes outside-in signaling responses by the ?V?3 vitronectin receptor.
Volume: 125
Issue: 12
Pages: 1995-2004
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Genotype
Genotype
Symbol: Itgb1/Itgb1 Tg(KRT5-cre)5132Jlj/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Edil3/? Itgb1/Itgb1
Background: involves: 129X1/SvJ * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Publication
39986371 | J:363211
 
First Author: Yang MW
Year: 2025
Journal: Cancer Lett
Title: SRSF12 deficiency enhances tumor innervation and accelerates pancreatic tumorigenesis.
Volume: 616
Pages: 217563
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Publication
29242271 | J:272099
First Author: Lu Q
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: SNRK (Sucrose Nonfermenting 1-Related Kinase) Promotes Angiogenesis In Vivo.
Volume: 38
Issue: 2
Pages: 373-385
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Publication
23691241 | J:204265
First Author: Sosa LJ
Year: 2013
Journal: PLoS One
Title: Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance.
Volume: 8
Issue: 5
Pages: e64521
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Publication
39975575 | J:378696
 
First Author: Wang Y
Year: 2025
Journal: Research (Wash D C)
Title: Regulating Integrin ?1 to Restore Gonadotropin-Releasing Hormone-Tanycyte Unit Function in Polycystic Ovary Syndrome-Related Hypothalamic Dysregulation.
Volume: 8
Pages: 0619
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Publication
36438492 | J:334222
First Author: Sun Y
Year: 2022
Journal: Theranostics
Title: Ninj2 regulates Schwann cells development by interfering laminin-integrin signaling.
Volume: 12
Issue: 17
Pages: 7307-7318
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Publication
19776386 | J:156644
First Author: Tajiri Y
Year: 2010
Journal: Biol Reprod
Title: Tubulointerstitial nephritis antigen-like 1 is expressed in the uterus and binds with integrins in decidualized endometrium during postimplantation in mice.
Volume: 82
Issue: 2
Pages: 263-70
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Publication
29599141 | J:285155
First Author: Wagner JUG
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Switch in Laminin ?2 to Laminin ?1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.
Volume: 38
Issue: 5
Pages: 1170-1177
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Publication
36438565 | J:332051
 
First Author: Riffo E
Year: 2022
Journal: Front Cell Dev Biol
Title: The Sall2 transcription factor promotes cell migration regulating focal adhesion turnover and integrin ?1 expression.
Volume: 10
Pages: 1031262
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Publication
32501543 | J:301408
First Author: Sevilla-Movilla S
Year: 2020
Journal: J Pathol
Title: Upregulated expression and function of the ?4?1 integrin in multiple myeloma cells resistant to bortezomib.
Volume: 252
Issue: 1
Pages: 29-40
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Protein
Q61673
Organism: Mus musculus/domesticus
Length: 27  
Fragment?: true
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Protein
P09022
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: false
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Protein
P17919
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
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Protein
Q01822
Organism: Mus musculus/domesticus
Length: 328  
Fragment?: false
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Protein
B9EHK7
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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