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Search results 1401 to 1500 out of 3295 for Kras

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Type Details Score
Publication
34294846 | J:311003
First Author: Xu G
Year: 2021
Journal: Oncogene
Title: The deubiquitinase USP16 functions as an oncogenic factor in K-RAS-driven lung tumorigenesis.
Volume: 40
Issue: 36
Pages: 5482-5494
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17404571 | J:163128
First Author: Allen NP
Year: 2007
Journal: Oncogene
Title: RASSF6 is a novel member of the RASSF family of tumor suppressors.
Volume: 26
Issue: 42
Pages: 6203-11
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Publication
3865197 | J:8114
First Author: Guerrero I
Year: 1985
Journal: Proc Natl Acad Sci U S A
Title: Loss of the normal N-ras allele in a mouse thymic lymphoma induced by a chemical carcinogen.
Volume: 82
Issue: 23
Pages: 7810-4
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Publication
14583591 | J:86399
First Author: Zhang Z
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice.
Volume: 100
Issue: 22
Pages: 12642-7
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Publication
8324828 | J:14935
First Author: Shultz LD
Year: 1993
Journal: Cell
Title: Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene.
Volume: 73
Issue: 7
Pages: 1445-54
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Publication
21339733 | J:174642
First Author: Seux M
Year: 2011
Journal: Oncogene
Title: TP53INP1 decreases pancreatic cancer cell migration by regulating SPARC expression.
Volume: 30
Issue: 27
Pages: 3049-61
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Publication
19738040 | J:153508
First Author: Regala RP
Year: 2009
Journal: Cancer Res
Title: Atypical protein kinase C{iota} is required for bronchioalveolar stem cell expansion and lung tumorigenesis.
Volume: 69
Issue: 19
Pages: 7603-11
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Publication
30503750 | J:272592
First Author: Farack L
Year: 2019
Journal: Dev Cell
Title: Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas.
Volume: 48
Issue: 1
Pages: 115-125.e4
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Publication
19330036 | J:147455
First Author: Granville CA
Year: 2009
Journal: PLoS One
Title: A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis.
Volume: 4
Issue: 3
Pages: e5061
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Publication
21317921 | J:173695
First Author: Serres MP
Year: 2011
Journal: Oncogene
Title: Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro.
Volume: 30
Issue: 25
Pages: 2846-58
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Publication
33606996 | J:305988
First Author: Yu M
Year: 2021
Journal: Mol Cell
Title: Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation.
Volume: 81
Issue: 6
Pages: 1216-1230.e9
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11713472 | J:109368
First Author: Ohno M
Year: 2001
Journal: Nat Neurosci
Title: Inducible, pharmacogenetic approaches to the study of learning and memory.
Volume: 4
Issue: 12
Pages: 1238-43
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17277161 | J:143972
First Author: Khalaf WF
Year: 2007
Journal: J Immunol
Title: K-ras is critical for modulating multiple c-kit-mediated cellular functions in wild-type and Nf1+/- mast cells.
Volume: 178
Issue: 4
Pages: 2527-34
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Publication
26452035 | J:310992
First Author: Pan Y
Year: 2015
Journal: Oncotarget
Title: Deletion of cyclooxygenase-2 inhibits K-ras-induced lung carcinogenesis.
Volume: 6
Issue: 36
Pages: 38816-26
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18713982 | J:138959
First Author: Tinder TL
Year: 2008
Journal: J Immunol
Title: MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma.
Volume: 181
Issue: 5
Pages: 3116-25
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30423293 | J:266848
First Author: Volk A
Year: 2018
Journal: Cancer Cell
Title: A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis.
Volume: 34
Issue: 5
Pages: 707-723.e7
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18264106 | J:204653
First Author: Miller AJ
Year: 2008
Journal: Nat Methods
Title: Tractable Cre-lox system for stochastic alteration of genes in mice.
Volume: 5
Issue: 3
Pages: 227-9
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24430184 | J:207982
First Author: Li H
Year: 2014
Journal: J Clin Invest
Title: Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis.
Volume: 124
Issue: 2
Pages: 835-46
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14706336 | J:87973
First Author: Hingorani SR
Year: 2003
Journal: Cancer Cell
Title: Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.
Volume: 4
Issue: 6
Pages: 437-50
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21512141 | J:172205
First Author: Charles RP
Year: 2011
Journal: Cancer Res
Title: Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse.
Volume: 71
Issue: 11
Pages: 3863-71
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23999427 | J:203922
First Author: White RA
Year: 2013
Journal: J Clin Invest
Title: Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.
Volume: 123
Issue: 10
Pages: 4390-404
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23063435 | J:199742
First Author: Peschard P
Year: 2012
Journal: Curr Biol
Title: Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.
Volume: 22
Issue: 21
Pages: 2063-8
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26996122 | J:234412
First Author: Wang P
Year: 2016
Journal: Int J Cancer
Title: Predictive imaging of chemotherapeutic response in a transgenic mouse model of pancreatic cancer.
Volume: 139
Issue: 3
Pages: 712-8
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22892241 | J:187371
First Author: Andreadi C
Year: 2012
Journal: Genes Dev
Title: The intermediate-activity (L597V)BRAF mutant acts as an epistatic modifier of oncogenic RAS by enhancing signaling through the RAF/MEK/ERK pathway.
Volume: 26
Issue: 17
Pages: 1945-58
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18614544 | J:138868
First Author: Hegedus B
Year: 2008
Journal: Hum Mol Genet
Title: Neurofibromin regulates somatic growth through the hypothalamic-pituitary axis.
Volume: 17
Issue: 19
Pages: 2956-66
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23143308 | J:193977
First Author: Maeda Y
Year: 2012
Journal: J Clin Invest
Title: Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.
Volume: 122
Issue: 12
Pages: 4388-400
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21358804 | J:171087
First Author: Samuel MS
Year: 2011
Journal: PLoS One
Title: K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity.
Volume: 6
Issue: 2
Pages: e17143
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17690114 | J:127727
First Author: Pandey J
Year: 2007
Journal: Carcinogenesis
Title: Modulation of tumor induction and progression of oncogenic K-ras-positive tumors in the presence of TGF- b1 haploinsufficiency.
Volume: 28
Issue: 12
Pages: 2589-96
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29930325 | J:266087
First Author: Liu Y
Year: 2018
Journal: Nat Commun
Title: Mitotic polarization of transcription factors during asymmetric division establishes fate of forming cancer cells.
Volume: 9
Issue: 1
Pages: 2424
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34020945 | J:314143
 
First Author: Guo Y
Year: 2021
Journal: Sci Adv
Title: Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells.
Volume: 7
Issue: 21
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39485842 | J:357852
First Author: Mennuni M
Year: 2024
Journal: Sci Adv
Title: High mitochondrial DNA levels accelerate lung adenocarcinoma progression.
Volume: 10
Issue: 44
Pages: eadp3481
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20421486 | J:160298
First Author: Weinberg F
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
Volume: 107
Issue: 19
Pages: 8788-93
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26279302 | J:309335
First Author: Zhang S
Year: 2016
Journal: Oncogene
Title: Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.
Volume: 35
Issue: 19
Pages: 2485-95
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23284900 | J:195622
First Author: Avila JL
Year: 2012
Journal: PLoS One
Title: Notch1 is not required for acinar-to-ductal metaplasia in a model of Kras-induced pancreatic ductal adenocarcinoma.
Volume: 7
Issue: 12
Pages: e52133
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28288993 | J:243130
First Author: Ajona D
Year: 2017
Journal: Cancer Discov
Title: A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis.
Volume: 7
Issue: 7
Pages: 694-703
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Publication
23395000 | J:196610
First Author: Huber AL
Year: 2013
Journal: Mol Cell
Title: p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose.
Volume: 49
Issue: 6
Pages: 1049-59
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24713656 | J:212762
First Author: Amato KR
Year: 2014
Journal: J Clin Invest
Title: Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC.
Volume: 124
Issue: 5
Pages: 2037-49
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21625009 | J:174977
First Author: Hollander MC
Year: 2011
Journal: Carcinogenesis
Title: A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.
Volume: 32
Issue: 8
Pages: 1279-84
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24018559 | J:203916
First Author: Baek KH
Year: 2013
Journal: J Clin Invest
Title: Thrombospondin-1 mediates oncogenic Ras-induced senescence in premalignant lung tumors.
Volume: 123
Issue: 10
Pages: 4375-89
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22262169 | J:182425
First Author: Walter G
Year: 2012
Journal: Cell Cycle
Title: Mouse model for probing tumor suppressor activity of protein phosphatase 2A in diverse signaling pathways.
Volume: 11
Issue: 3
Pages: 451-9
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36598261 | J:352763
First Author: O'Brien VP
Year: 2023
Journal: mBio
Title: Helicobacter pylori Chronic Infection Selects for Effective Colonizers of Metaplastic Glands.
Volume: 14
Issue: 1
Pages: e0311622
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15024028 | J:89285
First Author: Murray NR
Year: 2004
Journal: J Cell Biol
Title: Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
Volume: 164
Issue: 6
Pages: 797-802
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28330997 | J:243129
First Author: Wang YA
Year: 2017
Journal: Mol Cancer Res
Title: IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 Signaling.
Volume: 15
Issue: 7
Pages: 896-904
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25038189 | J:222076
First Author: Xu B
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Promotion of lung tumor growth by interleukin-17.
Volume: 307
Issue: 6
Pages: L497-508
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25664850 | J:220549
First Author: Chen Y
Year: 2015
Journal: J Clin Invest
Title: Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma.
Volume: 125
Issue: 3
Pages: 1147-62
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37494452 | J:338531
First Author: Reyes-Castro RA
Year: 2023
Journal: Sci Adv
Title: Phosphorylated nuclear DICER1 promotes open chromatin state and lineage plasticity of AT2 tumor cells in lung adenocarcinomas.
Volume: 9
Issue: 30
Pages: eadf6210
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23913633 | J:211986
First Author: Belmont L
Year: 2014
Journal: Int J Cancer
Title: Expression of TLR9 in tumor-infiltrating mononuclear cells enhances angiogenesis and is associated with a worse survival in lung cancer.
Volume: 134
Issue: 4
Pages: 765-77
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20086246 | J:161573
First Author: Zaslavsky A
Year: 2010
Journal: Blood
Title: Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis.
Volume: 115
Issue: 22
Pages: 4605-13
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8944028 | J:36997
First Author: Fijneman RJ
Year: 1996
Journal: Nat Genet
Title: Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3, and Sluc4, that influence the susceptibility to lung cancer in the mouse.
Volume: 14
Issue: 4
Pages: 465-7
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7813906 | J:21801
First Author: Festing MF
Year: 1994
Journal: Genet Res
Title: At least four genes and sex are associated with susceptibility to urethane-induced pulmonary adenomas in mice.
Volume: 64
Issue: 2
Pages: 99-106
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24743474 | J:215194
First Author: Dow LE
Year: 2014
Journal: PLoS One
Title: Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.
Volume: 9
Issue: 4
Pages: e95236
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25301067 | J:258859
First Author: Terry MR
Year: 2015
Journal: Cell Death Differ
Title: Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo.
Volume: 22
Issue: 5
Pages: 719-30
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20975663 | J:167639
First Author: Sjogren AK
Year: 2011
Journal: Leukemia
Title: Inactivating GGTase-I reduces disease phenotypes in a mouse model of K-RAS-induced myeloproliferative disease.
Volume: 25
Issue: 1
Pages: 186-9
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19710506 | J:153839
First Author: Cutts BA
Year: 2009
Journal: Blood
Title: Nf1 deficiency cooperates with oncogenic K-RAS to induce acute myeloid leukemia in mice.
Volume: 114
Issue: 17
Pages: 3629-32
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29792386 | J:275033
First Author: Jamalpour M
Year: 2018
Journal: Tumour Biol
Title: Disparate effects of Shb gene deficiency on disease characteristics in murine models of myeloid, B-cell, and T-cell leukemia.
Volume: 40
Issue: 4
Pages: 1010428318771472
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28691711 | J:250331
 
First Author: Huang J
Year: 2017
Journal: Nat Commun
Title: Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.
Volume: 8
Pages: 15999
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21555567 | J:171896
First Author: Shaw AT
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress.
Volume: 108
Issue: 21
Pages: 8773-8
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34644378 | J:317338
First Author: Hasebe K
Year: 2021
Journal: Carcinogenesis
Title: Trefoil factor family 2 inhibits cholangiocarcinogenesis by regulating the PTEN pathway in mice.
Volume: 42
Issue: 12
Pages: 1496-1505
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15665300 | J:95509
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Glioma formation in neurofibromatosis 1 reflects preferential activation of K-RAS in astrocytes.
Volume: 65
Issue: 1
Pages: 236-45
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15805275 | J:97360
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors.
Volume: 65
Issue: 7
Pages: 2755-60
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20876733 | J:164880
First Author: Lee DY
Year: 2010
Journal: Genes Dev
Title: Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner.
Volume: 24
Issue: 20
Pages: 2317-29
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32641778 | J:295341
First Author: Beel S
Year: 2020
Journal: Nat Commun
Title: κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis.
Volume: 11
Issue: 1
Pages: 3409
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21335545 | J:170465
First Author: Symonds JM
Year: 2011
Journal: Cancer Res
Title: Protein kinase C δ is a downstream effector of oncogenic K-ras in lung tumors.
Volume: 71
Issue: 6
Pages: 2087-97
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Publication
24213573 | J:216273
First Author: Wang IC
Year: 2014
Journal: Oncogene
Title: Foxm1 transcription factor is required for the initiation of lung tumorigenesis by oncogenic Kras(G12D.).
Volume: 33
Issue: 46
Pages: 5391-6
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20081861 | J:157079
First Author: Houghton AM
Year: 2010
Journal: Nat Med
Title: Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth.
Volume: 16
Issue: 2
Pages: 219-23
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24667377 | J:259219
First Author: Sanchez-Laorden B
Year: 2014
Journal: Sci Signal
Title: BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling.
Volume: 7
Issue: 318
Pages: ra30
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26880805 | J:231612
First Author: Yan Y
Year: 2016
Journal: Cancer Res
Title: KLF4-Mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis.
Volume: 76
Issue: 8
Pages: 2419-31
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24148820 | J:206523
First Author: Abrigo M
Year: 2014
Journal: Carcinogenesis
Title: Impairing squamous differentiation by Klf4 deletion is sufficient to initiate tongue carcinoma development upon K-Ras activation in mice.
Volume: 35
Issue: 3
Pages: 662-9
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26113043 | J:250091
First Author: Yu T
Year: 2016
Journal: Cell Death Differ
Title: KLF4 regulates adult lung tumor-initiating cells and represses K-Ras-mediated lung cancer.
Volume: 23
Issue: 2
Pages: 207-15
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10871846 | J:62962
First Author: Ise K
Year: 2000
Journal: Oncogene
Title: Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis.
Volume: 19
Issue: 26
Pages: 2951-6
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27381829 | J:253760
 
First Author: Chiblak S
Year: 2016
Journal: Sci Rep
Title: K-Ras and cyclooxygenase-2 coactivation augments intraductal papillary mucinous neoplasm and Notch1 mimicking human pancreas lesions.
Volume: 6
Pages: 29455
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Publication
23536795 | J:200177
First Author: Tapfer A
Year: 2013
Journal: PLoS One
Title: X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model.
Volume: 8
Issue: 3
Pages: e58439
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21084261 | J:168599
First Author: Mohammed A
Year: 2010
Journal: Cancer Prev Res (Phila)
Title: The epidermal growth factor receptor inhibitor gefitinib prevents the progression of pancreatic lesions to carcinoma in a conditional LSL-KrasG12D/+ transgenic mouse model.
Volume: 3
Issue: 11
Pages: 1417-26
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Publication
31100067 | J:277221
First Author: Hao F
Year: 2019
Journal: PLoS One
Title: Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice.
Volume: 14
Issue: 5
Pages: e0216603
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31114758 | J:281850
 
First Author: Dréau D
Year: 2019
Journal: Front Oncol
Title: Combining the Specific Anti-MUC1 Antibody TAB004 and Lip-MSA-IL-2 Limits Pancreatic Cancer Progression in Immune Competent Murine Models of Pancreatic Ductal Adenocarcinoma.
Volume: 9
Pages: 330
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29121082 | J:252764
First Author: Veite-Schmahl MJ
Year: 2017
Journal: PLoS One
Title: The Mouse Model of Pancreatic Cancer Atlas (MMPCA) for classification of pancreatic cancer lesions: A large histological investigation of the Ptf1aCre/+;LSL-KrasG12D/+ transgenic mouse model of pancreatic cancer.
Volume: 12
Issue: 11
Pages: e0187552
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25923219 | J:221104
 
First Author: LaConti JJ
Year: 2015
Journal: BMC Genomics
Title: Distinct serum metabolomics profiles associated with malignant progression in the KrasG12D mouse model of pancreatic ductal adenocarcinoma.
Volume: 16 Suppl 1
Pages: S1
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21738581 | J:174427
First Author: LaConti JJ
Year: 2011
Journal: PLoS One
Title: Tissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancer.
Volume: 6
Issue: 6
Pages: e20687
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Publication
28697176 | J:309128
First Author: Veite-Schmahl MJ
Year: 2017
Journal: Br J Cancer
Title: HMGA1 expression levels are elevated in pancreatic intraepithelial neoplasia cells in the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer.
Volume: 117
Issue: 5
Pages: 639-647
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Publication
31068602 | J:279841
First Author: Leal AS
Year: 2019
Journal: Sci Rep
Title: The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in KrasG12D; Pdx1-Cre (KC) mice.
Volume: 9
Issue: 1
Pages: 7072
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28698299 | J:244541
First Author: Mello SS
Year: 2017
Journal: Genes Dev
Title: Neat1 is a p53-inducible lincRNA essential for transformation suppression.
Volume: 31
Issue: 11
Pages: 1095-1108
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29713060 | J:264005
First Author: Handler J
Year: 2018
Journal: Oncogene
Title: Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-β exposure.
Volume: 37
Issue: 31
Pages: 4334-4342
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28419443 | J:250518
First Author: Janakiram NB
Year: 2017
Journal: Immunology
Title: Loss of natural killer T cells promotes pancreatic cancer in LSL-KrasG12D/+ mice.
Volume: 152
Issue: 1
Pages: 36-51
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24466367 | J:264441
First Author: Mohammed A
Year: 2013
Journal: Transl Oncol
Title: Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling.
Volume: 6
Issue: 6
Pages: 649-59
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23019409 | J:232014
First Author: Rao CV
Year: 2012
Journal: Neoplasia
Title: Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) mice.
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