| Type |
Details |
Score |
| Publication |
| First Author: |
Godden JW |
| Year: |
1991 |
| Journal: |
Science |
| Title: |
The 2.3 angstrom X-ray structure of nitrite reductase from Achromobacter cycloclastes. |
| Volume: |
253 |
| Issue: |
5018 |
| Pages: |
438-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Santiago B |
| Year: |
1999 |
| Journal: |
Gene |
| Title: |
Sequence analysis, characterization and CO-specific transcription of the cox gene cluster on the megaplasmid pHCG3 of Oligotropha carboxidovorans. |
| Volume: |
236 |
| Issue: |
1 |
| Pages: |
115-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Banci L |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Solution structure of Cox11, a novel type of beta-immunoglobulin-like fold involved in CuB site formation of cytochrome c oxidase. |
| Volume: |
279 |
| Issue: |
33 |
| Pages: |
34833-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Han AR |
| Year: |
2016 |
| Journal: |
Biochemistry |
| Title: |
Essential Role of the Linker Region in the Higher Catalytic Efficiency of a Bifunctional MsrA-MsrB Fusion Protein. |
| Volume: |
55 |
| Issue: |
36 |
| Pages: |
5117-27 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
The oxidation of methionine residues in proteins is considered to be one of the consequences of oxidative damage to cells, which in many cases leads to the loss of biological activity. Peptide methionine sulphoxide reductase (Msr) reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide, (MetO), to methionine []. Methionine (Met) can be oxidised to the R and S diastereomers of methionine sulfoxide (MetO). Methionine sulfoxide reductases A (MsrA) and B (MsrB) reduce MetO back to Met in a stereospecific manner, acting on the S and R forms, respectively. Msr is present in most living organisms [, ].Many bacteria, particularly pathogens, possess methionine sulfoxide reductase MsrA and MsrB as a fusion form (MsrAB) []. This entry includes MsrB and the fusion form of these enzymes. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Cytochrome c oxidase assembly protein is essential for the assembly of functional cytochrome oxidase protein. In eukaryotes it is an integral protein of the mitochondrial inner membrane. Cox11 is essential for the insertion of Cu(I) ions to form the CuB site. This is essential for the stability of other structures in subunit I, for example haems a and a3, and the magnesium/manganese centre. Cox11 is probably only required in sub-stoichiometric amounts relative to the structural units []. The C-terminal region of the protein is known to form a dimer. Each monomer coordinates one Cu(I) ion via three conserved cysteine residues (111, 208 and 210) in Saccharomyces cerevisiae (). Met 224 is also thought to play a role in copper transfer or stabilising the copper site []. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
These enzymes are involved in nitrate assimilation in the denitrification pathway. The 3D structure of the copper-containing nitrite reductase (NIR) from Achromobacter cycloclastes has been determined to 2.3A resolution []. The enzyme is a trimer, each monomer of which contains two Greek key β-barrel domains (similar to that of plastocyanin) and houses two copper sites. The two copper atoms in the monomer comprise a type I copper site (Cu-I: two His, one Cys and one Met ligand) that plays a crucial role for electron transfer from pseudoazurin to the type II copper site (Cu-II: three His and one solvent ligand), the catalytic centre of NIR for the reduction ofnitrite. The Cu-II site lies at the bottom of a 12A deep solvent channel and is the site to which the substrate (NO2-) binds []. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Homologous_superfamily |
| Description: |
Cytochrome c oxidase assembly protein is essential for the assembly of functional cytochrome oxidase protein. In eukaryotes it is an integral protein of the mitochondrial inner membrane. Cox11 is essential for the insertion of Cu(I) ions to form the CuB site. Thisis essential for the stability of other structures in subunit I, for example haems a and a3, and the magnesium/manganese centre. Cox11 is probably only required in sub-stoichiometric amounts relative to the structural units []. The C-terminal region of the protein is known to form a dimer. Each monomer coordinates one Cu(I) ion via three conserved cysteine residues (111, 208 and 210) in Saccharomyces cerevisiae (). Met 224 is also thought to play a role in copper transfer or stabilising the copper site [].The copper binding motif is composed of two highly conserved cysteines and is located on one side of a β-barrel structure []. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Conserved_site |
| Description: |
Aspartate kinase () (AK) catalyzes the first reaction in the aspartate pathway; the phosphorylation of aspartate. The product of this reaction can then be used in the biosynthesis of lysine or in the pathway leading to homoserine, which participates in the biosynthesis of threonine, isoleucine and methionine [].In bacteria there are three different aspartate kinase isozymes which differ in sensitivity to repression and inhibition by Lys, Met and Thr. AK1 and AK2 are bifunctional enzymes which both consist of an N-terminal AK domain and a C-terminal homoserine dehydrogenase domain. AK1 is involved in threonine biosynthesis and AK2, in that of methionine. The third isozyme, AK3 is monofunctional and involved in lysine synthesis. In archaea and plants there may be a single isozyme of AK which in plants is multifunctional.This entry represents a region encoding aspartate kinase activity found in both the monofunctional and bifunctional enzymes.Synonym(s): Aspartokinase |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
275
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
135
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hiser L |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
Cox11p is required for stable formation of the Cu(B) and magnesium centers of cytochrome c oxidase. |
| Volume: |
275 |
| Issue: |
1 |
| Pages: |
619-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carr HS |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
Yeast Cox11, a protein essential for cytochrome c oxidase assembly, is a Cu(I)-binding protein. |
| Volume: |
277 |
| Issue: |
34 |
| Pages: |
31237-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sperandio B |
| Year: |
2007 |
| Journal: |
J Bacteriol |
| Title: |
Control of methionine synthesis and uptake by MetR and homocysteine in Streptococcus mutans. |
| Volume: |
189 |
| Issue: |
19 |
| Pages: |
7032-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maxon ME |
| Year: |
1989 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Regulation of methionine synthesis in Escherichia coli: effect of the MetR protein on the expression of the metE and metR genes. |
| Volume: |
86 |
| Issue: |
1 |
| Pages: |
85-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu WF |
| Year: |
1995 |
| Journal: |
J Bacteriol |
| Title: |
Characterization of a second MetR-binding site in the metE metR regulatory region of Salmonella typhimurium. |
| Volume: |
177 |
| Issue: |
7 |
| Pages: |
1834-9 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
MetR, a member of the LysR family, is a positive regulator for the metA, metE, metF, and metH genes []. The sulfur-containing amino acid methionine is the universal initiator of protein synthesis in all known organisms and its derivative S-adenosylmethionine (SAM) and autoinducer-2 (AI-2) are involved in various cellular processes. SAM plays a central role as methyl donor in methylation reactions, which are essential for the biosynthesis of phospholipids, proteins, DNA and RNA. The interspecies signaling molecule AI-2 is involved in cell-cell communication process (quorum sensing) and gene regulation in bacteria. Although methionine biosynthetic enzymes and metabolic pathways are well conserved in bacteria, the regulation of methionine biosynthesis involves various regulatory mechanisms. In Escherichia coli and Salmonella enterica serovar Typhimurium, MetJ and MetR regulate the expression of methionine biosynthetic genes []. The MetJ repressor negatively regulates the E. coli met genes, except for metH []. Several of these genes are also under the positive control of MetR with homocysteine as a co-inducer. In Bacillus subtilis, the met genes are controlled by S-box termination-antitermination system. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2).The PBP2 are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate- binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction [, , ]. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hara K |
| Year: |
2014 |
| Journal: |
Cell Stem Cell |
| Title: |
Mouse spermatogenic stem cells continually interconvert between equipotent singly isolated and syncytial states. |
| Volume: |
14 |
| Issue: |
5 |
| Pages: |
658-72 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Igs2/Igs2<+> Tg(Pbsn-cre)4Prb/? |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 * FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Igs2/Igs2<+> Pten/Pten Tg(Pbsn-cre)4Prb/? |
| Background: |
involves: 129 * C57BL/6 * DBA/2 * FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ctnnb1/Ctnnb1<+> Igs2/Igs2<+> Tg(Pbsn-cre)4Prb/? |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 * FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gfra1/Gfra1<+> Tg(CAG-cat,-EGFP)39Miya/? |
| Background: |
involves: C57BL/6NJcl * DBA/2NJcl |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giza JI |
| Year: |
2018 |
| Journal: |
Neuron |
| Title: |
The BDNF Val66Met Prodomain Disassembles Dendritic Spines Altering Fear Extinction Circuitry and Behavior. |
| Volume: |
99 |
| Issue: |
1 |
| Pages: |
163-178.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tolbert WD |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist. |
| Volume: |
104 |
| Issue: |
37 |
| Pages: |
14592-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lan MS |
| Year: |
1994 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
cDNA sequence and genomic organization of mouse secretin. |
| Volume: |
200 |
| Issue: |
2 |
| Pages: |
1066-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Erickson T |
| Year: |
2017 |
| Journal: |
Elife |
| Title: |
Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt). |
| Volume: |
6 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li S |
| Year: |
2020 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Hepsin enhances liver metabolism and inhibits adipocyte browning in mice. |
| Volume: |
117 |
| Issue: |
22 |
| Pages: |
12359-12367 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Corns LF |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
4015 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liang X |
| Year: |
2021 |
| Journal: |
Neuron |
| Title: |
CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells. |
| Volume: |
109 |
| Issue: |
13 |
| Pages: |
2131-2149.e15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ballesteros A |
| Year: |
2018 |
| Journal: |
Elife |
| Title: |
Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins. |
| Volume: |
7 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Politi K |
| Year: |
2010 |
| Journal: |
Dis Model Mech |
| Title: |
Erlotinib resistance in mouse models of epidermal growth factor receptor-induced lung adenocarcinoma. |
| Volume: |
3 |
| Issue: |
1-2 |
| Pages: |
111-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanmukhappa K |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
Plasmin-mediated proteolysis is required for hepatocyte growth factor activation during liver repair. |
| Volume: |
284 |
| Issue: |
19 |
| Pages: |
12917-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morena D |
| Year: |
2016 |
| Journal: |
Elife |
| Title: |
Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes. |
| Volume: |
5 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ghosh A |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
In Vivo Cell Fate Tracing Provides No Evidence for Mesenchymal to Epithelial Transition in Adult Fallopian Tube and Uterus. |
| Volume: |
31 |
| Issue: |
6 |
| Pages: |
107631 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shah VV |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
5389 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Henneman L |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer. |
| Volume: |
112 |
| Issue: |
27 |
| Pages: |
8409-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Van Mater D |
| Year: |
2018 |
| Journal: |
JCI Insight |
| Title: |
Injury promotes sarcoma development in a genetically and temporally restricted manner. |
| Volume: |
3 |
| Issue: |
20 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sampaolesi M |
| Year: |
2003 |
| Journal: |
Science |
| Title: |
Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts. |
| Volume: |
301 |
| Issue: |
5632 |
| Pages: |
487-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ognjenovic NB |
| Year: |
2020 |
| Journal: |
Dev Cell |
| Title: |
Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors. |
| Volume: |
55 |
| Issue: |
5 |
| Pages: |
544-557.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Quinn HM |
| Year: |
2021 |
| Journal: |
Cancer Res |
| Title: |
YAP and β-Catenin Cooperate to Drive Oncogenesis in Basal Breast Cancer. |
| Volume: |
81 |
| Issue: |
8 |
| Pages: |
2116-2127 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mervis CB |
| Year: |
2012 |
| Journal: |
Am J Hum Genet |
| Title: |
Duplication of GTF2I results in separation anxiety in mice and humans. |
| Volume: |
90 |
| Issue: |
6 |
| Pages: |
1064-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bi L |
| Year: |
1995 |
| Journal: |
Nat Genet |
| Title: |
Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
119-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gao F |
| Year: |
2022 |
| Journal: |
Cell Rep |
| Title: |
Hedgehog-responsive PDGFRa(+) fibroblasts maintain a unique pool of alveolar epithelial progenitor cells during alveologenesis. |
| Volume: |
39 |
| Issue: |
1 |
| Pages: |
110608 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takayama H |
| Year: |
1996 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development. |
| Volume: |
93 |
| Issue: |
12 |
| Pages: |
5866-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
DÃaz-GarcÃa CM |
| Year: |
2021 |
| Journal: |
Elife |
| Title: |
The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle. |
| Volume: |
10 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giacobini P |
| Year: |
2008 |
| Journal: |
J Cell Biol |
| Title: |
Semaphorin 4D regulates gonadotropin hormone-releasing hormone-1 neuronal migration through PlexinB1-Met complex. |
| Volume: |
183 |
| Issue: |
3 |
| Pages: |
555-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Han P |
| Year: |
2020 |
| Journal: |
Sci Adv |
| Title: |
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes. |
| Volume: |
6 |
| Issue: |
11 |
| Pages: |
eaaz1580 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu P |
| Year: |
2011 |
| Journal: |
Nat Med |
| Title: |
Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanisms. |
| Volume: |
17 |
| Issue: |
9 |
| Pages: |
1116-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Graybuck LT |
| Year: |
2021 |
| Journal: |
Neuron |
| Title: |
Enhancer viruses for combinatorial cell-subclass-specific labeling. |
| Volume: |
109 |
| Issue: |
9 |
| Pages: |
1449-1464.e13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rose Li Y |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
394 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hashimoto K |
| Year: |
2007 |
| Journal: |
Bioessays |
| Title: |
BDNF variant linked to anxiety-related behaviors. |
| Volume: |
29 |
| Issue: |
2 |
| Pages: |
116-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Spencer JL |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
BDNF variant Val66Met interacts with estrous cycle in the control of hippocampal function. |
| Volume: |
107 |
| Issue: |
9 |
| Pages: |
4395-400 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee MS |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
3404 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ballesteros A |
| Year: |
2022 |
| Journal: |
Sci Adv |
| Title: |
Regulation of membrane homeostasis by TMC1 mechanoelectrical transduction channels is essential for hearing. |
| Volume: |
8 |
| Issue: |
31 |
| Pages: |
eabm5550 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu S |
| Year: |
2019 |
| Journal: |
Elife |
| Title: |
TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice. |
| Volume: |
8 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qiu X |
| Year: |
2023 |
| Journal: |
Cell Rep |
| Title: |
The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells. |
| Volume: |
42 |
| Issue: |
3 |
| Pages: |
112245 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kaverina NV |
| Year: |
2017 |
| Journal: |
Stem Cell Reports |
| Title: |
WT1 Is Necessary for the Proliferation and Migration of Cells of Renin Lineage Following Kidney Podocyte Depletion. |
| Volume: |
9 |
| Issue: |
4 |
| Pages: |
1152-1166 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee JH |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
526 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brondi M |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
High-Accuracy Detection of Neuronal Ensemble Activity in Two-Photon Functional Microscopy Using Smart Line Scanning. |
| Volume: |
30 |
| Issue: |
8 |
| Pages: |
2567-2580.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Crewe C |
| Year: |
2019 |
| Journal: |
JCI Insight |
| Title: |
SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1. |
| Volume: |
5 |
| Issue: |
15 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Beurg M |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
2185 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kurima K |
| Year: |
2015 |
| Journal: |
Cell Rep |
| Title: |
TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia. |
| Volume: |
12 |
| Issue: |
10 |
| Pages: |
1606-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Heidenreich S |
| Year: |
2020 |
| Journal: |
J Biol Chem |
| Title: |
The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation. |
| Volume: |
295 |
| Issue: |
50 |
| Pages: |
17158-17168 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen J |
| Year: |
2013 |
| Journal: |
Nat Genet |
| Title: |
Vitamin C modulates TET1 function during somatic cell reprogramming. |
| Volume: |
45 |
| Issue: |
12 |
| Pages: |
1504-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang CR |
| Year: |
1993 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
HMT, encoded by H-2M3, is a neoclassical major histocompatibility class I antigen. |
| Volume: |
90 |
| Issue: |
7 |
| Pages: |
2784-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boutet A |
| Year: |
2006 |
| Journal: |
EMBO J |
| Title: |
Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney. |
| Volume: |
25 |
| Issue: |
23 |
| Pages: |
5603-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu L |
| Year: |
2017 |
| Journal: |
Stem Cell Reports |
| Title: |
Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation. |
| Volume: |
9 |
| Issue: |
5 |
| Pages: |
1692-1705 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Beaudet A |
| Year: |
1986 |
| Journal: |
Am J Hum Genet |
| Title: |
Linkage of cystic fibrosis to two tightly linked DNA markers: joint report from a collaborative study. |
| Volume: |
39 |
| Issue: |
6 |
| Pages: |
681-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellman SE |
| Year: |
1987 |
| Journal: |
Gene |
| Title: |
Characterization of mouse H3.3-like histone genes. |
| Volume: |
59 |
| Issue: |
1 |
| Pages: |
29-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maminta ML |
| Year: |
1992 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Identification of a novel tyrosine kinase receptor-like molecule in neuroblastomas. |
| Volume: |
189 |
| Issue: |
2 |
| Pages: |
1077-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kubo S |
| Year: |
1993 |
| Journal: |
Gene |
| Title: |
The gene encoding mouse lymphocyte antigen Ly-49: structural analysis and the 5'-flanking sequence. |
| Volume: |
136 |
| Issue: |
1-2 |
| Pages: |
329-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rong S |
| Year: |
1994 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. |
| Volume: |
91 |
| Issue: |
11 |
| Pages: |
4731-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Quantin B |
| Year: |
1995 |
| Journal: |
Dev Dyn |
| Title: |
Restricted expression of the ron gene encoding the macrophage stimulating protein receptor during mouse development. |
| Volume: |
204 |
| Issue: |
4 |
| Pages: |
383-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ueland J |
| Year: |
2009 |
| Journal: |
Dev Dyn |
| Title: |
A novel role for the chemokine receptor Cxcr4 in kidney morphogenesis: an in vitro study. |
| Volume: |
238 |
| Issue: |
5 |
| Pages: |
1083-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morales J |
| Year: |
2009 |
| Journal: |
Am J Hum Genet |
| Title: |
Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. |
| Volume: |
85 |
| Issue: |
5 |
| Pages: |
558-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Feng Y |
| Year: |
2011 |
| Journal: |
Cancer Discov |
| Title: |
Anti-MET targeted therapy has come of age: the first durable complete response with MetMAb in metastatic gastric cancer. |
| Volume: |
1 |
| Issue: |
7 |
| Pages: |
550-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Valent P |
| Year: |
2012 |
| Journal: |
Nat Rev Cancer |
| Title: |
Cancer stem cell definitions and terminology: the devil is in the details. |
| Volume: |
12 |
| Issue: |
11 |
| Pages: |
767-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Balboula AZ |
| Year: |
2015 |
| Journal: |
Biol Reprod |
| Title: |
RBBP4 regulates histone deacetylation and bipolar spindle assembly during oocyte maturation in the mouse. |
| Volume: |
92 |
| Issue: |
4 |
| Pages: |
105 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alotaibi H |
| Year: |
2015 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Enhancer cooperativity as a novel mechanism underlying the transcriptional regulation of E-cadherin during mesenchymal to epithelial transition. |
| Volume: |
1849 |
| Issue: |
6 |
| Pages: |
731-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jang S |
| Year: |
2016 |
| Journal: |
Neuron |
| Title: |
Glycolytic Enzymes Localize to Synapses under Energy Stress to Support Synaptic Function. |
| Volume: |
90 |
| Issue: |
2 |
| Pages: |
278-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rady I |
| Year: |
2017 |
| Journal: |
Cancer Lett |
| Title: |
Melittin, a major peptide component of bee venom, and its conjugates in cancer therapy. |
| Volume: |
402 |
|
| Pages: |
16-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hao X |
| Year: |
2017 |
| Journal: |
FEBS Lett |
| Title: |
Novel immunoassays to detect methionine adenosyltransferase activity and quantify S-adenosylmethionine. |
| Volume: |
591 |
| Issue: |
8 |
| Pages: |
1114-1125 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Manganelli G |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Modulation of the pentose phosphate pathway induces endodermal differentiation in embryonic stem cells. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
e29321 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li S |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
Myosin-VIIa is expressed in multiple isoforms and essential for tensioning the hair cell mechanotransduction complex. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
2066 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ballesteros A |
| Year: |
2022 |
| Journal: |
Sci Rep |
| Title: |
Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
13764 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jiang Z |
| Year: |
2023 |
| Journal: |
Nat Commun |
| Title: |
Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
4313 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
798
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2477
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1052
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
424
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kast RJ |
| Year: |
2019 |
| Journal: |
Elife |
| Title: |
FOXP2 exhibits projection neuron class specific expression, but is not required for multiple aspects of cortical histogenesis. |
| Volume: |
8 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Green CD |
| Year: |
2018 |
| Journal: |
Dev Cell |
| Title: |
A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq. |
| Volume: |
46 |
| Issue: |
5 |
| Pages: |
651-667.e10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuwano T |
| Year: |
2021 |
| Journal: |
PLoS One |
| Title: |
Generation and characterization of a Meflin-CreERT2 transgenic line for lineage tracing in white adipose tissue. |
| Volume: |
16 |
| Issue: |
3 |
| Pages: |
e0248267 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rafalski JA |
| Year: |
1988 |
| Journal: |
J Biol Chem |
| Title: |
Structure of the yeast HOM3 gene which encodes aspartokinase. |
| Volume: |
263 |
| Issue: |
5 |
| Pages: |
2146-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cooper A |
| Year: |
1994 |
| Journal: |
FEBS Lett |
| Title: |
Calorimetric studies of the energetics of protein-DNA interactions in the E. coli methionine repressor (MetJ) system. |
| Volume: |
348 |
| Issue: |
1 |
| Pages: |
41-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Einsle O |
| Year: |
2000 |
| Journal: |
J Biol Inorg Chem |
| Title: |
Crystal structure of plantacyanin, a basic blue cupredoxin from spinach. |
| Volume: |
5 |
| Issue: |
5 |
| Pages: |
666-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koch M |
| Year: |
2005 |
| Journal: |
J Am Chem Soc |
| Title: |
Crystal structures of oxidized and reduced stellacyanin from horseradish roots. |
| Volume: |
127 |
| Issue: |
1 |
| Pages: |
158-66 |
|
•
•
•
•
•
|