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Search results 1401 to 1500 out of 1772 for Parkinson

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Type Details Score
Publication
20356833 | J:164560
First Author: Lou H
Year: 2010
Journal: J Biol Chem
Title: Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.
Volume: 285
Issue: 23
Pages: 17648-61
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Publication
21467220 | J:171363
First Author: Ros-Bernal F
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism.
Volume: 108
Issue: 16
Pages: 6632-7
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Publication
32629384 | J:294617
 
First Author: Jaberi E
Year: 2020
Journal: EBioMedicine
Title: Identification of unique and shared mitochondrial DNA mutations in neurodegeneration and cancer by single-cell mitochondrial DNA structural variation sequencing (MitoSV-seq).
Volume: 57
Pages: 102868
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Publication
28963550 | J:255487
First Author: Llavero Hurtado M
Year: 2017
Journal: Sci Rep
Title: Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo.
Volume: 7
Issue: 1
Pages: 12412
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Publication
20639202 | J:166391
First Author: Schwindinger WF
Year: 2010
Journal: J Biol Chem
Title: Adenosine A2A receptor signaling and golf assembly show a specific requirement for the gamma7 subtype in the striatum.
Volume: 285
Issue: 39
Pages: 29787-96
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Publication
20053987 | J:160720
First Author: Loeb V
Year: 2010
Journal: J Biol Chem
Title: The transgenic overexpression of alpha-synuclein and not its related pathology associates with complex I inhibition.
Volume: 285
Issue: 10
Pages: 7334-43
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Publication
20823226 | J:164352
First Author: Ko HS
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function.
Volume: 107
Issue: 38
Pages: 16691-6
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Publication
27348587 | J:232550
First Author: Brahmachari S
Year: 2016
Journal: J Clin Invest
Title: Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration.
Volume: 126
Issue: 8
Pages: 2970-88
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Publication
32643147 | J:306983
First Author: Suarez LM
Year: 2020
Journal: Mov Disord
Title: Dopamine D1 Receptors Regulate Spines in Striatal Direct-Pathway and Indirect-Pathway Neurons.
Volume: 35
Issue: 10
Pages: 1810-1821
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Publication
23671637 | J:202178
First Author: Jones J
Year: 2013
Journal: PLoS One
Title: Stem cells from wildtype and Friedreich's ataxia mice present similar neuroprotective properties in dorsal root ganglia cells.
Volume: 8
Issue: 5
Pages: e62807
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Publication
30571694 | J:269924
First Author: Bardai FH
Year: 2018
Journal: PLoS Biol
Title: Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics.
Volume: 16
Issue: 12
Pages: e2006265
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Publication
27859541 | J:350195
First Author: Migdalska-Richards A
Year: 2016
Journal: Ann Neurol
Title: Ambroxol effects in glucocerebrosidase and α-synuclein transgenic mice.
Volume: 80
Issue: 5
Pages: 766-775
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Publication
23027932 | J:190303
First Author: Tesla R
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis.
Volume: 109
Issue: 42
Pages: 17016-21
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Publication
23159549 | J:203379
First Author: Liu Y
Year: 2013
Journal: Neurobiol Aging
Title: Matrix metalloproteinase-12 contributes to neuroinflammation in the aged brain.
Volume: 34
Issue: 4
Pages: 1231-9
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Publication
30726572 | J:352831
First Author: Perez-Rosello T
Year: 2019
Journal: Mov Disord
Title: Enhanced striatopallidal gamma-aminobutyric acid (GABA)(A) receptor transmission in mouse models of huntington's disease.
Volume: 34
Issue: 5
Pages: 684-696
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Publication
16260631 | J:102361
First Author: Ellis CE
Year: 2005
Journal: Mol Cell Biol
Title: Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein.
Volume: 25
Issue: 22
Pages: 10190-201
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Publication
22870339 | J:189656
First Author: Smidt MP
Year: 2012
Journal: PLoS One
Title: Spatial and temporal lineage analysis of a Pitx3-driven Cre-recombinase knock-in mouse model.
Volume: 7
Issue: 8
Pages: e42641
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Publication
30084972 | J:266880
First Author: Huang X
Year: 2018
Journal: Hum Mol Genet
Title: CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.
Volume: 27
Issue: 22
Pages: 3881-3900
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Publication
23390134 | J:194967
First Author: Zongaro S
Year: 2013
Journal: Hum Mol Genet
Title: The 3' UTR of FMR1 mRNA is a target of miR-101, miR-129-5p and miR-221: implications for the molecular pathology of FXTAS at the synapse.
Volume: 22
Issue: 10
Pages: 1971-82
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Publication
23739956 | J:198648
First Author: Harms AS
Year: 2013
Journal: J Neurosci
Title: MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration.
Volume: 33
Issue: 23
Pages: 9592-600
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Publication
21865652 | J:178238
First Author: Kim KY
Year: 2011
Journal: J Clin Invest
Title: Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells.
Volume: 121
Issue: 9
Pages: 3701-12
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Publication
23152496 | J:193741
First Author: Kubli DA
Year: 2013
Journal: J Biol Chem
Title: Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction.
Volume: 288
Issue: 2
Pages: 915-26
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Publication
16517603 | J:112711
First Author: Rosen KM
Year: 2006
Journal: J Biol Chem
Title: Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells.
Volume: 281
Issue: 18
Pages: 12809-16
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Publication
30378174 | J:267367
First Author: Singh K
Year: 2018
Journal: Glia
Title: Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation.
Volume: 66
Issue: 11
Pages: 2427-2437
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Publication
21930938 | J:177137
First Author: Zhang C
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect.
Volume: 108
Issue: 39
Pages: 16259-64
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Publication
23297226 | J:193256
First Author: Sardi SP
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies.
Volume: 110
Issue: 9
Pages: 3537-42
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Publication
15589522 | J:104902
First Author: Jiang C
Year: 2005
Journal: Exp Neurol
Title: Age-dependent dopaminergic dysfunction in Nurr1 knockout mice.
Volume: 191
Issue: 1
Pages: 154-62
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Publication
31734439 | J:285592
 
First Author: Zhang J
Year: 2020
Journal: Neurobiol Aging
Title: Apoptosis signal regulating kinase 1 deletion mitigates α-synuclein pre-formed fibril propagation in mice.
Volume: 85
Pages: 49-57
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Publication
22460798 | J:183629
First Author: Johnson BN
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax.
Volume: 109
Issue: 16
Pages: 6283-8
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Publication
25799501 | J:219329
First Author: Zhang S
Year: 2015
Journal: PLoS One
Title: Olfactory dysfunction and neurotransmitter disturbance in olfactory bulb of transgenic mice expressing human A53T mutant α-synuclein.
Volume: 10
Issue: 3
Pages: e0119928
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Publication
25002524 | J:212256
First Author: Sacino AN
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
Volume: 111
Issue: 29
Pages: 10732-7
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Publication
32502569 | J:298658
 
First Author: Zhang J
Year: 2020
Journal: Neuroscience
Title: Transglutaminase 2 Depletion Attenuates α-Synuclein Mediated Toxicity in Mice.
Volume: 441
Pages: 58-64
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Publication
20071342 | J:161080
First Author: Lee HJ
Year: 2010
Journal: J Biol Chem
Title: Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies.
Volume: 285
Issue: 12
Pages: 9262-72
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Publication
21296890 | J:170923
First Author: Desplats P
Year: 2011
Journal: J Biol Chem
Title: Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases.
Volume: 286
Issue: 11
Pages: 9031-7
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Publication
22211740 | J:184337
First Author: Kohl Z
Year: 2012
Journal: Eur J Neurosci
Title: Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model.
Volume: 35
Issue: 1
Pages: 10-9
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Publication
33460487 | J:361303
First Author: Feyder M
Year: 2021
Journal: Mov Disord
Title: Involvement of Autophagy in Levodopa-Induced Dyskinesia.
Volume: 36
Issue: 5
Pages: 1137-1146
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Publication
15699033 | J:98730
First Author: Higuchi M
Year: 2005
Journal: J Biol Chem
Title: Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors.
Volume: 280
Issue: 15
Pages: 15229-37
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Publication
25501001 | J:222655
First Author: Bifsha P
Year: 2014
Journal: PLoS Genet
Title: Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra.
Volume: 10
Issue: 12
Pages: e1004863
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Publication
15755737 | J:99089
First Author: Callio J
Year: 2005
Journal: J Biol Chem
Title: Manganese superoxide dismutase protects against 6-hydroxydopamine injury in mouse brains.
Volume: 280
Issue: 18
Pages: 18536-42
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Publication
26374899 | J:236660
First Author: Atagi Y
Year: 2015
Journal: J Biol Chem
Title: Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).
Volume: 290
Issue: 43
Pages: 26043-50
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Publication
30503521 | J:269242
First Author: McClymont SA
Year: 2018
Journal: Am J Hum Genet
Title: Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons.
Volume: 103
Issue: 6
Pages: 874-892
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Publication
24986517 | J:214243
First Author: Mittal D
Year: 2014
Journal: Cancer Res
Title: Antimetastatic effects of blocking PD-1 and the adenosine A2A receptor.
Volume: 74
Issue: 14
Pages: 3652-8
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Publication
30364204 | J:310818
 
First Author: Harmuth T
Year: 2018
Journal: Front Mol Neurosci
Title: Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3.
Volume: 11
Pages: 368
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Publication
34077533 | J:321364
First Author: Araki M
Year: 2021
Journal: Hum Mol Genet
Title: BORCS6 is involved in the enlargement of lung lamellar bodies in Lrrk2 knockout mice.
Volume: 30
Issue: 17
Pages: 1618-1631
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Publication
29315561 | J:261520
First Author: Komnig D
Year: 2018
Journal: J Neurochem
Title: Faim2 contributes to neuroprotection by erythropoietin in transient brain ischemia.
Volume: 145
Issue: 3
Pages: 258-270
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Publication
31125602 | J:282999
 
First Author: Bermúdez ML
Year: 2019
Journal: Neuroscience
Title: Evaluation of Carnosine Intervention in the Thy1-aSyn Mouse Model of Parkinson's Disease.
Volume: 411
Pages: 270-278
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Publication
27398617 | J:236156
First Author: Howe MW
Year: 2016
Journal: Nature
Title: Rapid signalling in distinct dopaminergic axons during locomotion and reward.
Volume: 535
Issue: 7613
Pages: 505-10
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Publication
28746897 | J:249746
 
First Author: Song W
Year: 2017
Journal: Neurobiol Aging
Title: Parkinsonian features in aging GFAP.HMOX1 transgenic mice overexpressing human HO-1 in the astroglial compartment.
Volume: 58
Pages: 163-179
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Publication
31180611 | J:277689
First Author: Cressatti M
Year: 2019
Journal: Glia
Title: Glial HMOX1 expression promotes central and peripheral α-synuclein dysregulation and pathogenicity in parkinsonian mice.
Volume: 67
Issue: 9
Pages: 1730-1744
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Publication
22898818 | J:191580
First Author: Liu L
Year: 2012
Journal: J Biol Chem
Title: Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein.
Volume: 287
Issue: 39
Pages: 32307-11
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Publication
18238775 | J:135332
First Author: Zhou W
Year: 2008
Journal: J Biol Chem
Title: Transgenic mice overexpressing tyrosine-to-cysteine mutant human alpha-synuclein: a progressive neurodegenerative model of diffuse Lewy body disease.
Volume: 283
Issue: 15
Pages: 9863-70
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Publication
30048714 | J:268603
 
First Author: Kelly K
Year: 2018
Journal: Exp Neurol
Title: The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition.
Volume: 309
Pages: 1-13
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Publication
27321750 | J:234278
First Author: Quintana MT
Year: 2016
Journal: Am J Pathol
Title: Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling.
Volume: 186
Issue: 8
Pages: 1989-2007
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Publication
27845893 | J:290434
First Author: Pampalakis G
Year: 2017
Journal: Oncotarget
Title: KLK6 proteolysis is implicated in the turnover and uptake of extracellular alpha-synuclein species.
Volume: 8
Issue: 9
Pages: 14502-14515
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Publication
31291551 | J:290673
First Author: Yuan Y
Year: 2019
Journal: FASEB J
Title: PTENα regulates endocytosis and modulates olfactory function.
Volume: 33
Issue: 10
Pages: 11148-11162
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Publication
21127069 | J:168706
First Author: Qureshi HY
Year: 2011
Journal: J Biol Chem
Title: Parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and alpha-synuclein mutations promote Tau protein phosphorylation at Ser262 and destabilize microtubule cytoskeleton in vitro.
Volume: 286
Issue: 7
Pages: 5055-68
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Publication
16926154 | J:117196
First Author: Wislet-Gendebien S
Year: 2006
Journal: J Biol Chem
Title: Cytosolic proteins regulate alpha-synuclein dissociation from presynaptic membranes.
Volume: 281
Issue: 43
Pages: 32148-55
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Publication
18167346 | J:133684
First Author: Muchowski PJ
Year: 2008
Journal: J Biol Chem
Title: Noninvasive measurement of protein aggregation by mutant huntingtin fragments or alpha-synuclein in the lens.
Volume: 283
Issue: 10
Pages: 6330-6
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Publication
18838384 | J:143428
First Author: Park KM
Year: 2008
Journal: J Biol Chem
Title: Tumor necrosis factor-alpha potentiates intraneuronal Ca2+ signaling via regulation of the inositol 1,4,5-trisphosphate receptor.
Volume: 283
Issue: 48
Pages: 33069-79
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Publication
19289463 | J:150523
First Author: Wang J
Year: 2009
Journal: J Biol Chem
Title: 14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria.
Volume: 284
Issue: 21
Pages: 14011-9
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Publication
23335331 | J:195221
First Author: Schipanski A
Year: 2013
Journal: Genetics
Title: A novel interaction between aging and ER overload in a protein conformational dementia.
Volume: 193
Issue: 3
Pages: 865-76
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Publication
23401502 | J:195326
First Author: Wu WF
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis.
Volume: 110
Issue: 9
Pages: 3543-8
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Publication
23754283 | J:202717
First Author: Ren G
Year: 2013
Journal: J Biol Chem
Title: Zebrafish tyrosine hydroxylase 2 gene encodes tryptophan hydroxylase.
Volume: 288
Issue: 31
Pages: 22451-9
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Publication
24170860 | J:202886
First Author: Lagier-Tourenne C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration.
Volume: 110
Issue: 47
Pages: E4530-9
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Publication
23872112 | J:204103
First Author: Linares M
Year: 2013
Journal: Biochim Biophys Acta
Title: Glutathione peroxidase contributes with heme oxygenase-1 to redox balance in mouse brain during the course of cerebral malaria.
Volume: 1832
Issue: 12
Pages: 2009-18
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Publication
24381286 | J:205588
First Author: Guardia-Laguarta C
Year: 2014
Journal: J Neurosci
Title: α-Synuclein is localized to mitochondria-associated ER membranes.
Volume: 34
Issue: 1
Pages: 249-59
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Publication
26724386 | J:229947
First Author: Luo SX
Year: 2016
Journal: Am J Pathol
Title: Dopaminergic Neurons and Brain Reward Pathways: From Neurogenesis to Circuit Assembly.
Volume: 186
Issue: 3
Pages: 478-88
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Publication
26801612 | J:231222
First Author: Chaudhuri AD
Year: 2016
Journal: J Biol Chem
Title: MicroRNA-7 Regulates the Function of Mitochondrial Permeability Transition Pore by Targeting VDAC1 Expression.
Volume: 291
Issue: 12
Pages: 6483-93
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Publication
28173004 | J:238647
First Author: Ishizu N
Year: 2016
Journal: Hum Mol Genet
Title: Impaired striatal dopamine release in homozygous Vps35 D620N knock-in mice.
Volume: 25
Issue: 20
Pages: 4507-4517
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Publication
22751106 | J:255051
First Author: Ganat YM
Year: 2012
Journal: J Clin Invest
Title: Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment.
Volume: 122
Issue: 8
Pages: 2928-39
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Publication
33317145 | J:304336
 
First Author: Campolo M
Year: 2020
Journal: Int J Mol Sci
Title: TLR7/8 in the Pathogenesis of Parkinson's Disease.
Volume: 21
Issue: 24
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Publication
26378614 | J:319195
First Author: Du TT
Year: 2015
Journal: Autophagy
Title: GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A.
Volume: 11
Issue: 10
Pages: 1803-20
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Publication
33130818 | J:313507
First Author: Oh CK
Year: 2020
Journal: Cell Death Dis
Title: RING-finger protein 166 plays a novel pro-apoptotic role in neurotoxin-induced neurodegeneration via ubiquitination of XIAP.
Volume: 11
Issue: 10
Pages: 939
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Publication
38032732 | J:345714
 
First Author: Kanan MK
Year: 2024
Journal: JCI Insight
Title: Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration.
Volume: 9
Issue: 2
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Protein
A0A0J9YVC1
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: true
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Protein
Q3UQI5
Organism: Mus musculus/domesticus
Length: 831  
Fragment?: true
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Protein
Q3UYM6
Organism: Mus musculus/domesticus
Length: 866  
Fragment?: true
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Protein
Q3UZD9
Organism: Mus musculus/domesticus
Length: 958  
Fragment?: true
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Protein
A0PJB5
Organism: Mus musculus/domesticus
Length: 842  
Fragment?: true
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Protein
A0A087WS25
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: true
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Protein
E9Q770
Organism: Mus musculus/domesticus
Length: 958  
Fragment?: true
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Protein
A0A0J9YUC1
Organism: Mus musculus/domesticus
Length: 900  
Fragment?: true
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Protein
Q3UTK0
Organism: Mus musculus/domesticus
Length: 826  
Fragment?: true
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Publication
12775772 | J:84435
First Author: Evangelista M
Year: 2003
Journal: J Cell Sci
Title: Formins: signaling effectors for assembly and polarization of actin filaments.
Volume: 116
Issue: Pt 13
Pages: 2603-11
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Protein
Q3TC93
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
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Protein
A0A1W2P6R8
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
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Publication
25281315 | J:218546
 
First Author: Solís O
Year: 2015
Journal: Neurobiol Dis
Title: Nitric oxide synthase inhibition decreases l-DOPA-induced dyskinesia and the expression of striatal molecular markers in Pitx3(-/-) aphakia mice.
Volume: 73
Pages: 49-59
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Publication
20033184 | J:156878
First Author: Rosemann M
Year: 2010
Journal: Mamm Genome
Title: Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 ( 416insG ) mice.
Volume: 21
Issue: 1-2
Pages: 13-27
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