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Search results 1401 to 1500 out of 1688 for Prnp

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Type Details Score
Allele
Prnp/Prnd<tm1Aag> | MGI:3047635
Name: prion protein; targeted mutation 1, Adriano Aguzzi
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
18183299 | J:131324
First Author: Béringue V
Year: 2008
Journal: PLoS One
Title: Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD.
Volume: 3
Issue: 1
Pages: e1419
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Publication
24850746 | J:214386
First Author: Halliez S
Year: 2014
Journal: J Virol
Title: Accelerated, spleen-based titration of variant Creutzfeldt-Jakob disease infectivity in transgenic mice expressing human prion protein with sensitivity comparable to that of survival time bioassay.
Volume: 88
Issue: 15
Pages: 8678-86
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Publication
27681129 | J:238016
First Author: Jaumain E
Year: 2016
Journal: J Virol
Title: Absence of Evidence for a Causal Link between Bovine Spongiform Encephalopathy Strain Variant L-BSE and Known Forms of Sporadic Creutzfeldt-Jakob Disease in Human PrP Transgenic Mice.
Volume: 90
Issue: 23
Pages: 10867-10874
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Publication
22282814 | J:181259
First Author: Béringue V
Year: 2012
Journal: Science
Title: Facilitated cross-species transmission of prions in extraneural tissue.
Volume: 335
Issue: 6067
Pages: 472-5
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Allele
Tg(Prnp-Abca1)EHol | MGI:3800823
Name: transgene insertion E, David M Holtzman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:4412388 | C57BL/6-Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz
Attribute String: coisogenic, mutant strain, transgenic
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Publication
28197095 | J:276720
 
First Author: Brendel M
Year: 2017
Journal: Front Aging Neurosci
Title: Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
Volume: 9
Pages: 8
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Publication
27097852 | J:324345
 
First Author: Srinivasan K
Year: 2016
Journal: Nat Commun
Title: Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses.
Volume: 7
Pages: 11295
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Publication
36906584 | J:339796
First Author: Ballweg A
Year: 2023
Journal: J Neuroinflammation
Title: [(18)F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data.
Volume: 20
Issue: 1
Pages: 68
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Publication
15922048 | J:98909
First Author: Woolley ML
Year: 2005
Journal: Behav Brain Res
Title: Age-related impairments in operant DMTP performance in the PS2APP mouse, a transgenic mouse model of Alzheimer's disease.
Volume: 161
Issue: 2
Pages: 220-8
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Publication
17008022 | J:116044
First Author: Güntert A
Year: 2006
Journal: Neuroscience
Title: High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain.
Volume: 143
Issue: 2
Pages: 461-75
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Strain
MGI:7424873 | C57BL/6-Tg(Prnp-ITM2B*)7Jckr/J
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:4452506 | C57BL/6-Tg(Prnp-ITM2B*)7Jckr
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:4839904 | B6.Cg-Tg(Prnp-PSEN2*N141I)30Jgr Tg(Thy1-APPSwe)71Jgr
Attribute String: congenic, mutant strain, transgenic
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Publication
17251422 | J:117779
First Author: Lopez-Lopez C
Year: 2007
Journal: J Neurosci
Title: Disturbed cross talk between insulin-like growth factor I and AMP-activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease.
Volume: 27
Issue: 4
Pages: 824-31
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Publication
15649694 | J:134624
First Author: von Kienlin M
Year: 2005
Journal: Neurobiol Dis
Title: Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span.
Volume: 18
Issue: 1
Pages: 32-9
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Strain
MGI:5003971 | STOCK Tg(Prnp-EGFP)IX28Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Allele
Tg(Mbp/Prnp)640Zbz | MGI:5314788
Name: transgene insertion 640, Universitatsspital Zurich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-MAPT*P301L)#Ruvi | MGI:5525087
Name: transgene insertion, Ruben Vidal
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp)E1Rchi | MGI:5563239
Name: transgene insertion E1, Roberto Chiesa
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*S170N*N174T)1020Aag | MGI:5569540
Name: transgene insertion 1020, Adriano Aguzzi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp/PRNP)1Drb | MGI:5762584
Name: transgene insertion 1, David R Brown
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:5908854 | B6.Cg-Tg(tetO/Prnp-MAPT)769Tli/J
Attribute String: mutant strain, congenic, transgenic
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Allele
Tg(tetO/Prnp-MAPT*K280)530Tli | MGI:5908855
Name: transgene insertion 530, Tong Li
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Tg(Prnp-Tardbp,-EGFP)19Zxu | MGI:6469530
Name: transgene insertion 19, Zuoshang Xu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Strain
MGI:6469538 | FVB/NJ-Tg(Prnp-Tardbp,-EGFP)19Zxu/J
Attribute String: coisogenic, mutant strain, transgenic
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Publication
35113871 | J:319624
First Author: Yang C
Year: 2022
Journal: PLoS One
Title: Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice.
Volume: 17
Issue: 2
Pages: e0255710
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Allele
Tg(Prnp-UBQLN2*P506T)#Hlp | MGI:6784048
Name: transgene insertion, Henry L Paulson
Allele Type: Transgenic
Attribute String: Epitope tag, Humanized sequence, Inserted expressed sequence
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Publication
29097807 | J:265116
First Author: Tsuiji H
Year: 2017
Journal: Sci Rep
Title: TDP-43 accelerates age-dependent degeneration of interneurons.
Volume: 7
Issue: 1
Pages: 14972
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Allele
Tg(Prnp-Abca1)DHol | MGI:7614750
Name: transgene insertion D, David M Holtzman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Prnp-MAPT)43Vle/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-MAPT)43Vle/Tg(Prnp-MAPT)43Vle
Background: involves: C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-PRNP*129V)139Tkit/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-PRNP)32Tkit/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-PRNP*129M)1Tkit/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp*D177N*M128V)A21Rchi/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp*D177N*M128V)A21Rchi/Tg(Prnp*D177N*M128V)A21Rchi
Background: involves: C57BL/6 * CBA
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/?
Background: C57BL/6-Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-ITM2B*)7Jckr/?
Background: C57BL/6-Tg(Prnp-ITM2B*)7Jckr
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-PSEN2*N141I)30Jgr/? Tg(Thy1-APPSwe)71Jgr/?
Background: B6.Cg-Tg(Prnp-PSEN2*N141I)30Jgr Tg(Thy1-APPSwe)71Jgr
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp*P101L)2247Sbp/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp*P101L)2866Sbp/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp*P101L)2862Sbp/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)4053Sbp/?
Background: involves: 129S7/SvEvBrd * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-MAPT)7Vle/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: involves: 129P2/OlaHsd * C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(PRNP)35Jcol/Tg(PRNP)35Jcol
Background: involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(PRNP)45Jcol/Tg(PRNP)45Jcol
Background: involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-UBQLN2)WT-hiHlp/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-UBQLN2)WT-lowHlp/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-UBQLN2*P506T)#Hlp/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Publication
22383525 | J:241474
First Author: Basak JM
Year: 2012
Journal: J Biol Chem
Title: Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes.
Volume: 287
Issue: 17
Pages: 13959-71
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Strain
MGI:7571105 | STOCK Prnp<tm1Cwe> Tg(Prnp*D177N*M128V)A21Rchi/Cnrm
Attribute String: mutant stock, targeted mutation, transgenic
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Strain
MGI:7571103 | B6.Cg-Prnp<tm1Cwe> Tg(Prnp*)A3Dah/Cnrm
Attribute String: mutant stock, targeted mutation, transgenic
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Strain
MGI:7571102 | B6.Cg-Prnp<tm1Cwe> Tg(Prnp*D177N*M128V)66Rchi/Cnrm
Attribute String: mutant stock, targeted mutation, transgenic
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Strain
MGI:2652558 | B6;129S7-Prnp<tm1Cwe> Tg(Prnp)d11Cwe/CweCnrm
Attribute String: mutant stock, targeted mutation, transgenic
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Publication
15618403 | J:95891
First Author: Chiesa R
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease.
Volume: 102
Issue: 1
Pages: 238-43
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Allele
Tg(Prnp)C4Cwe | MGI:2446641
Name: transgene insertion C4, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp)C15Cwe | MGI:2446644
Name: transgene insertion C15, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp)E11Cwe | MGI:2446646
Name: transgene insertion E11, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
20551516 | J:163788
First Author: Sigurdson CJ
Year: 2010
Journal: J Clin Invest
Title: A molecular switch controls interspecies prion disease transmission in mice.
Volume: 120
Issue: 7
Pages: 2590-9
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Publication
19478942 | J:148835
First Author: Karapetyan YE
Year: 2009
Journal: PLoS One
Title: Prion strain discrimination based on rapid in vivo amplification and analysis by the cell panel assay.
Volume: 4
Issue: 5
Pages: e5730
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Publication
36301895 | J:339386
First Author: Race B
Year: 2022
Journal: PLoS One
Title: Microglia have limited influence on early prion pathogenesis, clearance, or replication.
Volume: 17
Issue: 10
Pages: e0276850
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Publication
23871665 | J:201911
First Author: Kong Q
Year: 2013
Journal: Cell Rep
Title: Thermodynamic stabilization of the folded domain of prion protein inhibits prion infection in vivo.
Volume: 4
Issue: 2
Pages: 248-54
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Publication
16767691 | J:112007
First Author: Sasaki K
Year: 2006
Journal: J Pathol
Title: Clusterin expression in follicular dendritic cells associated with prion protein accumulation.
Volume: 209
Issue: 4
Pages: 484-91
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Publication
17020952 | J:116053
First Author: Sigurdson CJ
Year: 2006
Journal: J Virol
Title: Strain fidelity of chronic wasting disease upon murine adaptation.
Volume: 80
Issue: 24
Pages: 12303-11
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Publication
22811520 | J:187893
First Author: Saá P
Year: 2012
Journal: J Virol
Title: Strain-specific role of RNAs in prion replication.
Volume: 86
Issue: 19
Pages: 10494-504
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Publication
31513666 | J:279503
First Author: Hornemann S
Year: 2019
Journal: PLoS One
Title: Enhanced detection of prion infectivity from blood by preanalytical enrichment with peptoid-conjugated beads.
Volume: 14
Issue: 9
Pages: e0216013
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Publication
31329627 | J:277743
First Author: Bender H
Year: 2019
Journal: PLoS One
Title: PrPC knockdown by liposome-siRNA-peptide complexes (LSPCs) prolongs survival and normal behavior of prion-infected mice immunotolerant to treatment.
Volume: 14
Issue: 7
Pages: e0219995
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Publication
23484043 | J:200195
First Author: Wyckoff AC
Year: 2013
Journal: PLoS One
Title: Estimating prion adsorption capacity of soil by BioAssay of Subtracted Infectivity from Complex Solutions (BASICS).
Volume: 8
Issue: 3
Pages: e58630
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Publication
32454127 | J:292711
 
First Author: Callender JA
Year: 2020
Journal: Neurobiol Dis
Title: Prion protein post-translational modifications modulate heparan sulfate binding and limit aggregate size in prion disease.
Volume: 142
Pages: 104955
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Strain
MGI:3801181 | B6.Cg-Tg(Prnp-Abca1)EHol/J
Attribute String: transgenic, congenic
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Publication
25484285 | J:219296
 
First Author: Hanson JE
Year: 2015
Journal: Neurobiol Dis
Title: Altered GluN2B NMDA receptor function and synaptic plasticity during early pathology in the PS2APP mouse model of Alzheimer's disease.
Volume: 74
Pages: 254-62
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Publication
22805202 | J:218149
First Author: Kipanyula MJ
Year: 2012
Journal: Aging Cell
Title: Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2.
Volume: 11
Issue: 5
Pages: 885-93
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Publication
19066434 | J:154969
First Author: Ozmen L
Year: 2009
Journal: Neurodegener Dis
Title: Expression of transgenic APP mRNA is the key determinant for beta-amyloid deposition in PS2APP transgenic mice.
Volume: 6
Issue: 1-2
Pages: 29-36
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Allele
Tg(Pcp2-Prnp)E330Zbz | MGI:5014494
Name: transgene insertion E330, Zurich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*P101L)174Sbp | MGI:5487544
Name: transgene insertion 174, Stanley B Prusiner
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*)CDah | MGI:5563233
Name: transgene insertion C, David A Harris
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-PRNP*6OR)K6M6Pcg | MGI:5775412
Name: transgene insertion K6M6, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-PRNP*6OR)K6M16Pcg | MGI:5775417
Name: transgene insertion K6M16, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp/PRNP*ARR)FM18Pcg | MGI:5779521
Name: trangene insertion FM18, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp/PRNP*ARR)FF8Pcg | MGI:5779525
Name: transgene insertion FF8, Peter Griffiths
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp/PRNP*ARR)FM16Pcg | MGI:5779528
Name: transgene insertion FM16, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:5908858 | B6.Cg-Tg(tetO/Prnp-MAPT*K280)530Tli/J
Attribute String: transgenic, mutant strain, congenic
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Allele
Tg(PRNP)1536Gcte | MGI:6193853
Name: transgene insertion 1536, Glenn C Telling
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(PRNP)1534Gcte | MGI:6193854
Name: transgene insertion 1534, Glenn C Telling
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnd/Prnp/Prnd
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnd/Prnp/Prnd
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)c35Cwe/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)37Jcol/?
Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)46Jcol/?
Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-PRNP*129V)144Tkit/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-PRNP*)1Tkit/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-Abca1)EHol/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp*D177N*M128V)A21Rchi/Tg(Prnp*D177N*M128V)A21Rchi
Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp*D177N*M128V)A21Rchi/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp)a20Cwe/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom