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Search results 1401 to 1500 out of 1529 for Six2

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Type Details Score
Genotype
Genotype
Symbol: Tg(Six2-GFP/cre)1Amc/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Six2-GFP/cre)1Amc/?
Background: involves: C57BL/6 * CD-1
Zygosity: ot
Has Mutant Allele: true
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Publication
25804735 | J:220462
First Author: Li Y
Year: 2015
Journal: Development
Title: p53 Enables metabolic fitness and self-renewal of nephron progenitor cells.
Volume: 142
Issue: 7
Pages: 1228-41
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Publication
30268775 | J:270451
First Author: Baek JH
Year: 2018
Journal: Am J Pathol
Title: Deletion of the Mitochondrial Complex-IV Cofactor Heme A:Farnesyltransferase Causes Focal Segmental Glomerulosclerosis and Interferon Response.
Volume: 188
Issue: 12
Pages: 2745-2762
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Six2/Six2<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Six2/Six2<+>
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wwtr1/Wwtr1 Yap1/Yap1 Six2/Six2<+>
Background: involves: 129 * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wasl/Wasl Six2/Six2<+>
Background: involves: 129 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Six2-GFP/cre)1Amc/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Allele
Tg(Six2-EGFP/cre)1Amc | MGI:3845228
Name: transgene insertion 1, Andrew P McMahon
Allele Type: Transgenic
Attribute String: Recombinase
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Six2/Six2<+>
Background: involves: 129S4/SvJaeSor * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctdnep1/Ctdnep1 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Six2/Six2<+>
Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mdm2/Mdm2 Tg(Six2-GFP/cre)1Amc/?
Background: involves: 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mdm2/Mdm2 Tg(Six2-GFP/cre)1Amc/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mdm2/Mdm2<+> Tg(Six2-GFP/cre)1Amc/?
Background: involves: 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE56253 | p53 Enables Self Renewal of Nephron Progenitor Cells
Series Id: E-GEOD-56253
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
30894749 | J:283421
First Author: Liu Z
Year: 2019
Journal: Nature
Title: A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB.
Volume: 568
Issue: 7751
Pages: 249-253
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Publication
26057579 | J:225747
First Author: Jayewickreme CD
Year: 2015
Journal: Dev Biol
Title: Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1.
Volume: 405
Issue: 1
Pages: 21-32
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Publication
22669823 | J:185503
First Author: Yu CT
Year: 2012
Journal: Development
Title: COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival.
Volume: 139
Issue: 13
Pages: 2330-9
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Publication
21396121 | J:171720
 
First Author: Brunskill EW
Year: 2011
Journal: BMC Dev Biol
Title: Microarrays and RNA-Seq identify molecular mechanisms driving the end of nephron production.
Volume: 11
Pages: 15
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Publication
37815464 | J:342867
 
First Author: Stevenson MJ
Year: 2023
Journal: Dis Model Mech
Title: Altered binding affinity of SIX1-Q177R correlates with enhanced WNT5A and WNT pathway effector expression in Wilms tumor.
Volume: 16
Issue: 11
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Publication
20378824 | J:185938
First Author: Surendran K
Year: 2010
Journal: J Am Soc Nephrol
Title: Reduced Notch signaling leads to renal cysts and papillary microadenomas.
Volume: 21
Issue: 5
Pages: 819-32
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Publication
29408475 | J:272273
First Author: Fukunaga S
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Optimal route of diphtheria toxin administration to eliminate native nephron progenitor cells in vivo for kidney regeneration.
Volume: 496
Issue: 4
Pages: 1176-1182
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Strain
MGI:4356565 | STOCK Tg(Six2-EGFP/cre)1Amc/J
Attribute String: transgenic, mutant stock
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Genotype
Genotype
Symbol: Jag1/Jag1<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129/Sv * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jag1/Jag1 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129/Sv * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Six2-EGFP/cre)1Amc/?
Background: involves: C57BL/6J * CD-1
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mdm2/Mdm2 Tg(Six2-GFP/cre)1Amc/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Bgeo,-DsRed*MST)1Nagy/? Tg(Six2-GFP/cre)1Amc/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Six2-GFP/cre)1Amc/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Six2-EGFP/cre)1Amc/?
Background: STOCK
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eed/Eed Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Six2/Six2<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Six2/Six2<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Six2-EGFP/cre)1Amc/?
Background: involves: C57BL/6 * CD-1
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mirc1/Mirc1 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Six2-EGFP/cre)1Amc/?
Background: involves: CD-1
Zygosity: ot
Has Mutant Allele: true
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Publication
10508520 | J:57891
First Author: Schäfer K
Year: 1999
Journal: Nat Genet
Title: Early specification of limb muscle precursor cells by the homeobox gene Lbx1h.
Volume: 23
Issue: 2
Pages: 213-6
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Publication
25812847 | J:320688
First Author: Wada S
Year: 2015
Journal: Histochem Cell Biol
Title: H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro.
Volume: 144
Issue: 1
Pages: 13-20
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Publication
33113370 | J:306457
First Author: Fiorentino A
Year: 2020
Journal: Cell Rep
Title: Developmental Renal Glomerular Defects at the Origin of Glomerulocystic Disease.
Volume: 33
Issue: 4
Pages: 108304
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Publication
28446592 | J:252168
First Author: Cerqueira DM
Year: 2017
Journal: FASEB J
Title: Bim gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development.
Volume: 31
Issue: 8
Pages: 3540-3554
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Publication
19914235 | J:157258
First Author: Surendran K
Year: 2010
Journal: Dev Biol
Title: The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.
Volume: 337
Issue: 2
Pages: 386-95
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Publication
29335243 | J:293089
First Author: Zimmerman SE
Year: 2018
Journal: J Am Soc Nephrol
Title: Nephronectin Regulates Mesangial Cell Adhesion and Behavior in Glomeruli.
Volume: 29
Issue: 4
Pages: 1128-1140
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Publication
26634297 | J:228317
 
First Author: Muthukrishnan SD
Year: 2015
Journal: Nat Commun
Title: Concurrent BMP7 and FGF9 signalling governs AP-1 function to promote self-renewal of nephron progenitor cells.
Volume: 6
Pages: 10027
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Publication
32484794 | J:309007
 
First Author: Nechama M
Year: 2020
Journal: JCI Insight
Title: Rapamycin and dexamethasone during pregnancy prevent tuberous sclerosis complex-associated cystic kidney disease.
Volume: 5
Issue: 13
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Publication
36189831 | J:330244
 
First Author: Kwon HN
Year: 2022
Journal: Development
Title: Omics profiling identifies the regulatory functions of the MAPK/ERK pathway in nephron progenitor metabolism.
Volume: 149
Issue: 19
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Publication
32715474 | J:299813
First Author: Li B
Year: 2020
Journal: J Pathol
Title: ADAM10 mediates ectopic proximal tubule development and renal fibrosis through Notch signalling.
Volume: 252
Issue: 3
Pages: 274-289
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Publication
24920757 | J:212099
First Author: Rymer C
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Renal blood flow and oxygenation drive nephron progenitor differentiation.
Volume: 307
Issue: 3
Pages: F337-45
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Publication
26661650 | J:283125
First Author: Graca JA
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Comparative expression of the extracellular calcium-sensing receptor in the mouse, rat, and human kidney.
Volume: 310
Issue: 6
Pages: F518-33
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Publication
29611334 | J:315978
First Author: Song R
Year: 2018
Journal: Physiol Rep
Title: Conditional ablation of the prorenin receptor in nephron progenitor cells results in developmental programming of hypertension.
Volume: 6
Issue: 7
Pages: e13644
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Publication
30156115 | J:283498
First Author: Schenk LK
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Nephron-specific knockout of TMEM16A leads to reduced number of glomeruli and albuminuria.
Volume: 315
Issue: 6
Pages: F1777-F1786
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Publication
33687977 | J:306430
First Author: Möller-Kerutt A
Year: 2021
Journal: J Am Soc Nephrol
Title: Crumbs2 Is an Essential Slit Diaphragm Protein of the Renal Filtration Barrier.
Volume: 32
Issue: 5
Pages: 1053-1070
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Genotype
Genotype
Symbol: Dll1/Dll1<+> Jag1/Jag1 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129/Sv * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dll1/Dll1<+> Jag1/Jag1<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129/Sv * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dll1/Dll1 Jag1/Jag1<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129/Sv * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dll1/Dll1 Jag1/Jag1 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129/Sv * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dll1/Dll1 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129 * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col1a1/Col1a1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(EIF1AX-Lin28a)#Gqda/? Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Atp6ap2/Atp6ap2 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Atp6ap2/Atp6ap2<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Podxl/Podxl Podxl2/Podxl2 Six2/Six2<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cnnm2/Cnnm2 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Drosha/Drosha Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Srgap1/Srgap1 Six2/Six2<+>
Background: involves: 129 * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dnmt1/Dnmt1 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smarca4/Smarca4<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S2/SvPas * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smarca4/Smarca4 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S2/SvPas * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Six2-EGFP/cre)1Amc/? Uqcrq/Uqcrq<+>
Background: involves: CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Six2-EGFP/cre)1Amc/? Uqcrq/Uqcrq
Background: involves: CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2/Pax2<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1 * Swiss Webster
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2/Pax2 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1 * Swiss Webster
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Acly/Acly<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Acly/Acly Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox4/Sox4 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rap1a/Rap1a Rap1b/Rap1b Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S/SvEv * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Afdn/Afdn Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dnmt1/Dnmt1<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Mdm2/Mdm2 Tg(Six2-GFP/cre)1Amc/?
Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6NCr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ezh1/Ezh1<+> Ezh2/Ezh2 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ezh1/Ezh1 Ezh2/Ezh2 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ezh2/Ezh2 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dot1l/Dot1l Tg(Six2-EGFP/cre)1Amc/?
Background: involves: C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Map2k1/Map2k1 Map2k2/Map2k2 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129 * C57BL/6 * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Map2k1/Map2k1<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129 * C57BL/6 * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tet2/Tet2 Tet3/Tet3 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Six2-EGFP/cre)1Amc/? Vhl/Vhl
Background: involves: 129S4/SvJae * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Six2-EGFP/cre)1Amc/? Vhl/Vhl<+>
Background: involves: 129S4/SvJae * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hdac1/Hdac1 Hdac2/Hdac2 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129 * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Drosha/Drosha<+> Tg(Six2-EGFP/cre)1Amc/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Publication
17537789 | J:122521
First Author: Park JS
Year: 2007
Journal: Development
Title: Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development.
Volume: 134
Issue: 13
Pages: 2533-9
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Publication
19797679 | J:172930
First Author: Liu Z
Year: 2009
Journal: Genome Res
Title: Rapid identification of homologous recombinants and determination of gene copy number with reference/query pyrosequencing (RQPS).
Volume: 19
Issue: 11
Pages: 2081-9
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Publication
22792366 | J:189643
First Author: Maezawa Y
Year: 2012
Journal: PLoS One
Title: A new Cre driver mouse line, Tcf21/Pod1-Cre, targets metanephric mesenchyme.
Volume: 7
Issue: 7
Pages: e40547
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Publication
18371453 | J:148456
First Author: Humphreys BD
Year: 2008
Journal: Cell Stem Cell
Title: Intrinsic epithelial cells repair the kidney after injury.
Volume: 2
Issue: 3
Pages: 284-91
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Publication
27591083 | J:255143
First Author: Rasouly HM
Year: 2016
Journal: Kidney Int
Title: Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.
Volume: 90
Issue: 6
Pages: 1262-1273
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Publication
29945864 | J:264141
 
First Author: Zhang L
Year: 2018
Journal: Development
Title: EED, a member of the polycomb group, is required for nephron differentiation and the maintenance of nephron progenitor cells.
Volume: 145
Issue: 14
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Publication
29895697 | J:265138
First Author: Dionne LK
Year: 2018
Journal: J Cell Biol
Title: Centrosome amplification disrupts renal development and causes cystogenesis.
Volume: 217
Issue: 7
Pages: 2485-2501
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Publication
37276970 | J:337132
 
First Author: Hiremath C
Year: 2023
Journal: Dev Biol
Title: Rap1 regulates lumen continuity via Afadin in renal epithelia.
Volume: 501
Pages: 20-27
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Publication
38876267 | J:353091
 
First Author: Feola K
Year: 2024
Journal: Mol Metab
Title: Hepatic ketogenesis is not required for starvation adaptation in mice.
Volume: 86
Pages: 101967
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Publication
28154200 | J:289471
First Author: Weide T
Year: 2017
Journal: J Am Soc Nephrol
Title: Pals1 Haploinsufficiency Results in Proteinuria and Cyst Formation.
Volume: 28
Issue: 7
Pages: 2093-2107
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