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Search results 1401 to 1500 out of 1661 for Stat1

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Type Details Score
Publication
First Author: Fong CH
Year: 2008
Journal: J Exp Med
Title: An antiinflammatory role for IKKbeta through the inhibition of "classical" macrophage activation.
Volume: 205
Issue: 6
Pages: 1269-76
Publication      
First Author: Holgado A
Year: 2023
Journal: J Allergy Clin Immunol
Title: A20 is a master switch of IL-33 signaling in macrophages and determines IL-33-induced lung immunity.
Publication
First Author: Kalim KW
Year: 2012
Journal: J Immunol
Title: Immunoproteasome subunit LMP7 deficiency and inhibition suppresses Th1 and Th17 but enhances regulatory T cell differentiation.
Volume: 189
Issue: 8
Pages: 4182-93
Publication
First Author: Dai L
Year: 2020
Journal: J Cell Mol Med
Title: SARI suppresses colitis-associated cancer development by maintaining MCP-1-mediated tumour-associated macrophage recruitment.
Volume: 24
Issue: 1
Pages: 189-201
Publication
First Author: Xi H
Year: 2001
Journal: Oncogene
Title: Impaired class II transactivator expression in mice lacking interferon regulatory factor-2.
Volume: 20
Issue: 31
Pages: 4219-27
Publication
First Author: Thomsen MK
Year: 2013
Journal: J Clin Invest
Title: JUNB/AP-1 controls IFN-γ during inflammatory liver disease.
Volume: 123
Issue: 12
Pages: 5258-68
Publication
First Author: Grisouard J
Year: 2016
Journal: Blood
Title: JAK2 exon 12 mutant mice display isolated erythrocytosis and changes in iron metabolism favoring increased erythropoiesis.
Volume: 128
Issue: 6
Pages: 839-51
Publication
First Author: Chen X
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages.
Volume: 109
Issue: 42
Pages: E2865-74
Publication
First Author: He B
Year: 2015
Journal: Mol Cell Biol
Title: Human Glucocorticoid Receptor β Regulates Gluconeogenesis and Inflammation in Mouse Liver.
Volume: 36
Issue: 5
Pages: 714-30
Publication
First Author: Choi SH
Year: 2014
Journal: J Clin Invest
Title: Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis.
Volume: 124
Issue: 6
Pages: 2472-82
Publication
First Author: Yang X
Year: 2008
Journal: Dev Biol
Title: Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia.
Volume: 321
Issue: 1
Pages: 64-76
Publication
First Author: You W
Year: 2023
Journal: BMC Biol
Title: GADD45A regulates subcutaneous fat deposition and lipid metabolism by interacting with Stat1.
Volume: 21
Issue: 1
Pages: 212
Publication  
First Author: Song YS
Year: 2023
Journal: Cells
Title: Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells.
Volume: 12
Issue: 2
Publication
First Author: Ferrand A
Year: 2005
Journal: Cancer Res
Title: Signaling pathways associated with colonic mucosa hyperproliferation in mice overexpressing gastrin precursors.
Volume: 65
Issue: 7
Pages: 2770-7
Publication
First Author: Cudejko C
Year: 2011
Journal: Blood
Title: p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.
Volume: 118
Issue: 9
Pages: 2556-66
Publication
First Author: Li W
Year: 2002
Journal: J Biol Chem
Title: STAT3 contributes to the mitogenic response of hepatocytes during liver regeneration.
Volume: 277
Issue: 32
Pages: 28411-7
Publication
First Author: Grisouard J
Year: 2015
Journal: Blood
Title: Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2-V617F mouse model of MPN.
Volume: 125
Issue: 13
Pages: 2131-40
Publication
First Author: Miller JC
Year: 2010
Journal: Infect Immun
Title: The Lyme disease spirochete Borrelia burgdorferi utilizes multiple ligands, including RNA, for interferon regulatory factor 3-dependent induction of type I interferon-responsive genes.
Volume: 78
Issue: 7
Pages: 3144-53
Publication
First Author: Yao A
Year: 2014
Journal: Neurotherapeutics
Title: Programmed death 1 deficiency induces the polarization of macrophages/microglia to the M1 phenotype after spinal cord injury in mice.
Volume: 11
Issue: 3
Pages: 636-50
Publication
First Author: Watanabe T
Year: 2010
Journal: J Clin Invest
Title: NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.
Volume: 120
Issue: 5
Pages: 1645-62
Publication
First Author: Beurel E
Year: 2013
Journal: J Immunol
Title: Regulation of Th1 cells and experimental autoimmune encephalomyelitis by glycogen synthase kinase-3.
Volume: 190
Issue: 10
Pages: 5000-11
Publication
First Author: Solaymani-Mohammadi S
Year: 2019
Journal: PLoS Pathog
Title: Interleukin 21 collaborates with interferon-γ for the optimal expression of interferon-stimulated genes and enhances protection against enteric microbial infection.
Volume: 15
Issue: 2
Pages: e1007614
Publication
First Author: Knobeloch KP
Year: 2005
Journal: Mol Cell Biol
Title: Reexamination of the role of ubiquitin-like modifier ISG15 in the phenotype of UBP43-deficient mice.
Volume: 25
Issue: 24
Pages: 11030-4
Publication
First Author: Zhen Y
Year: 2018
Journal: J Leukoc Biol
Title: Mechanism of Mer receptor tyrosine kinase inhibition of glomerular endothelial cell inflammation.
Volume: 103
Issue: 4
Pages: 709-717
Publication
First Author: Menon MP
Year: 2006
Journal: Blood
Title: Core erythropoietin receptor signals for late erythroblast development.
Volume: 107
Issue: 7
Pages: 2662-72
Publication
First Author: Yue T
Year: 2022
Journal: Cell Death Differ
Title: MBD2 acts as a repressor to maintain the homeostasis of the Th1 program in type 1 diabetes by regulating the STAT1-IFN-γ axis.
Volume: 29
Issue: 1
Pages: 218-229
Publication
First Author: Zhang Q
Year: 2011
Journal: J Interferon Cytokine Res
Title: The role of Tyk2 in regulation of breast cancer growth.
Volume: 31
Issue: 9
Pages: 671-7
Publication
First Author: Shakya R
Year: 2013
Journal: Cancer Res
Title: Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.
Volume: 73
Issue: 2
Pages: 885-96
Publication
First Author: Fagoonee S
Year: 2008
Journal: J Immunol
Title: Lack of plasma protein hemopexin dampens mercury-induced autoimmune response in mice.
Volume: 181
Issue: 3
Pages: 1937-47
Publication
First Author: He C
Year: 2015
Journal: Diabetes
Title: AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1.
Volume: 64
Issue: 12
Pages: 4285-97
Publication
First Author: Ní Gabhann J
Year: 2014
Journal: PLoS One
Title: Btk regulates macrophage polarization in response to lipopolysaccharide.
Volume: 9
Issue: 1
Pages: e85834
Publication
First Author: Mittal M
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury.
Volume: 113
Issue: 50
Pages: E8151-E8158
Publication      
First Author: Maglakelidze N
Year: 2022
Journal: J Invest Dermatol
Title: AIRE Deficiency Leads to the Development of Alopecia Areata‒Like Lesions in Mice.
Publication
First Author: Murphy TL
Year: 2000
Journal: Mol Cell Biol
Title: Role of the Stat4 N domain in receptor proximal tyrosine phosphorylation.
Volume: 20
Issue: 19
Pages: 7121-31
Publication
First Author: Samarajiwa SA
Year: 2014
Journal: J Immunol
Title: Soluble IFN receptor potentiates in vivo type I IFN signaling and exacerbates TLR4-mediated septic shock.
Volume: 192
Issue: 9
Pages: 4425-35
Publication
First Author: Kissig M
Year: 2017
Journal: EMBO J
Title: PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing.
Volume: 36
Issue: 11
Pages: 1528-1542
Publication
First Author: Musthafa A
Year: 2023
Journal: Kobe J Med Sci
Title: Acute Amelioration of Inflammatory Activity Caused by Endothelin-2 Deficiency during Acute Lung Injury.
Volume: 69
Issue: 3
Pages: E96-E105
Publication
First Author: D'Agostino J
Year: 2012
Journal: J Biol Chem
Title: Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes.
Volume: 287
Issue: 21
Pages: 17777-88
Publication
First Author: Mahajan S
Year: 2020
Journal: J Immunol
Title: Diacylglycerol Kinase ζ Regulates Macrophage Responses in Juvenile Arthritis and Cytokine Storm Syndrome Mouse Models.
Volume: 204
Issue: 1
Pages: 137-146
Publication
First Author: Kanagavelu S
Year: 2015
Journal: Mucosal Immunol
Title: TIR-domain-containing adapter-inducing interferon-β (TRIF) regulates Th17-mediated intestinal immunopathology in colitis.
Volume: 8
Issue: 2
Pages: 296-306
Publication
First Author: Shutinoski B
Year: 2016
Journal: Cell Death Differ
Title: K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.
Volume: 23
Issue: 10
Pages: 1628-37
Publication
First Author: Mun HS
Year: 2003
Journal: Microbiol Immunol
Title: Pathogenicity of Toxoplasma gondii through B-2 cell-mediated downregulation of host defense responses.
Volume: 47
Issue: 7
Pages: 533-42
Publication
First Author: Hayashi T
Year: 2007
Journal: J Immunol
Title: IFN-gamma protects cerulein-induced acute pancreatitis by repressing NF-kappa B activation.
Volume: 178
Issue: 11
Pages: 7385-94
Publication
First Author: Ohno T
Year: 2020
Journal: Biochem Biophys Res Commun
Title: TSLP is a negative regulator of RANKL-induced osteoclastogenesis.
Volume: 530
Issue: 3
Pages: 508-512
Publication
First Author: Sato Y
Year: 2014
Journal: Biochem Biophys Res Commun
Title: IL-27 affects helper T cell responses via regulation of PGE2 production by macrophages.
Volume: 451
Issue: 2
Pages: 215-21
Publication
First Author: de Almeida Nagata DE
Year: 2014
Journal: Am J Pathol
Title: IL-27R-mediated regulation of IL-17 controls the development of respiratory syncytial virus-associated pathogenesis.
Volume: 184
Issue: 6
Pages: 1807-18
Publication
First Author: Kanai K
Year: 2017
Journal: J Immunol
Title: IL-35 Suppresses Lipopolysaccharide-Induced Airway Eosinophilia in EBI3-Deficient Mice.
Volume: 198
Issue: 1
Pages: 119-127
Publication
First Author: Bourdeau A
Year: 2007
Journal: Blood
Title: TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}.
Volume: 109
Issue: 10
Pages: 4220-8
Publication  
First Author: Leonard MR
Year: 2024
Journal: JCI Insight
Title: Aiolos promotes CXCR3 expression on Th1 cells via positive regulation of IFN-γ/STAT1 signaling.
Volume: 10
Issue: 1
Publication
First Author: Wong KA
Year: 2004
Journal: Mol Cell Biol
Title: Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance sumoylation but are not essential for embryogenesis and adult life.
Volume: 24
Issue: 12
Pages: 5577-86
Publication
First Author: Agarwal P
Year: 2015
Journal: J Invest Dermatol
Title: Simvastatin prevents and reverses depigmentation in a mouse model of vitiligo.
Volume: 135
Issue: 4
Pages: 1080-1088
Publication
First Author: Hanada T
Year: 2005
Journal: J Immunol
Title: Induction of hyper Th1 cell-type immune responses by dendritic cells lacking the suppressor of cytokine signaling-1 gene.
Volume: 174
Issue: 7
Pages: 4325-32
Publication
First Author: Lu Y
Year: 2006
Journal: J Biol Chem
Title: Loss of SOCS3 gene expression converts STAT3 function from anti-apoptotic to pro-apoptotic.
Volume: 281
Issue: 48
Pages: 36683-90
Publication
First Author: Movahedi K
Year: 2008
Journal: Blood
Title: Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity.
Volume: 111
Issue: 8
Pages: 4233-44
Publication  
First Author: Wang J
Year: 2022
Journal: J Clin Invest
Title: Breast cancer cell-derived microRNA-155 suppresses tumor progression via enhancing immune cell recruitment and antitumor function.
Volume: 132
Issue: 19
Publication
First Author: Lee HJ
Year: 2007
Journal: Biochem Pharmacol
Title: Rosmarinic acid inhibits indoleamine 2,3-dioxygenase expression in murine dendritic cells.
Volume: 73
Issue: 9
Pages: 1412-21
Publication
First Author: Yamamoto Y
Year: 2018
Journal: Sci Rep
Title: Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through the regulation of IL-6/stat3 signalling.
Volume: 8
Issue: 1
Pages: 15917
Publication
First Author: Baban B
Year: 2005
Journal: Int Immunol
Title: A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation.
Volume: 17
Issue: 7
Pages: 909-19
Publication
First Author: Roth W
Year: 2004
Journal: J Immunol
Title: PIASy-deficient mice display modest defects in IFN and Wnt signaling.
Volume: 173
Issue: 10
Pages: 6189-99
Publication
First Author: Liu YC
Year: 2021
Journal: Mol Ther
Title: Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation.
Volume: 29
Issue: 1
Pages: 376-395
Publication
First Author: Li J
Year: 2024
Journal: Cancer Immunol Immunother
Title: Targeting metabolic sensing switch GPR84 on macrophages for cancer immunotherapy.
Volume: 73
Issue: 3
Pages: 52
Publication  
First Author: Parihar SP
Year: 2021
Journal: Front Immunol
Title: IL-4-Responsive B Cells Are Detrimental During Chronic Tuberculosis Infection in Mice.
Volume: 12
Pages: 611673
Publication  
First Author: Zhu Z
Year: 2023
Journal: EBioMedicine
Title: The S1P receptor 1 antagonist Ponesimod reduces TLR4-induced neuroinflammation and increases Aβ clearance in 5XFAD mice.
Volume: 94
Pages: 104713
Publication
First Author: Min-Oo G
Year: 2014
Journal: J Exp Med
Title: Cytomegalovirus generates long-lived antigen-specific NK cells with diminished bystander activation to heterologous infection.
Volume: 211
Issue: 13
Pages: 2669-80
Publication
First Author: Yoshimoto T
Year: 2008
Journal: J Immunol
Title: Antiproliferative activity of IL-27 on melanoma.
Volume: 180
Issue: 10
Pages: 6527-35
Publication
First Author: Haynes LD
Year: 2015
Journal: J Immunol
Title: Cardif (MAVS) Regulates the Maturation of NK Cells.
Volume: 195
Issue: 5
Pages: 2157-67
Publication
First Author: Gau D
Year: 2023
Journal: J Biol Chem
Title: Vascular endothelial profilin-1 drives a protumorigenic tumor microenvironment and tumor progression in renal cancer.
Volume: 299
Issue: 8
Pages: 105044
Publication
First Author: Panchanathan R
Year: 2010
Journal: J Immunol
Title: Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.
Volume: 185
Issue: 12
Pages: 7385-93
Publication
First Author: Kwon MC
Year: 2008
Journal: EMBO J
Title: Crif1 is a novel transcriptional coactivator of STAT3.
Volume: 27
Issue: 4
Pages: 642-53
Publication
First Author: Lawrence DW
Year: 2018
Journal: PLoS One
Title: Reduced inflammation and cytokine production in NKLAM deficient mice during Streptococcus pneumoniae infection.
Volume: 13
Issue: 3
Pages: e0194202
Publication
First Author: Lawrence DW
Year: 2019
Journal: PLoS One
Title: Mice deficient in NKLAM have attenuated inflammatory cytokine production in a Sendai virus pneumonia model.
Volume: 14
Issue: 9
Pages: e0222802
Publication
First Author: Hong XY
Year: 2020
Journal: Signal Transduct Target Ther
Title: STAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of FTDP-17.
Volume: 5
Issue: 1
Pages: 295
Publication
First Author: Meares GP
Year: 2013
Journal: J Immunol
Title: AMP-activated protein kinase restricts IFN-γ signaling.
Volume: 190
Issue: 1
Pages: 372-80
Publication
First Author: Carron C
Year: 2000
Journal: Blood
Title: TEL-JAK2 transgenic mice develop T-cell leukemia.
Volume: 95
Issue: 12
Pages: 3891-9
Publication
First Author: Arndt L
Year: 2018
Journal: J Biol Chem
Title: Tribbles homolog 1 deficiency modulates function and polarization of murine bone marrow-derived macrophages.
Volume: 293
Issue: 29
Pages: 11527-11536
Publication
First Author: Prutsch N
Year: 2019
Journal: Leukemia
Title: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.
Volume: 33
Issue: 3
Pages: 696-709
Publication
First Author: Barik S
Year: 2018
Journal: J Immunol
Title: IL-4 and IL-13 Guide Early Thymic Progenitors To Mature toward Dendritic Cells.
Volume: 201
Issue: 10
Pages: 2947-2958
Publication
First Author: Teijaro JR
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: S1PR1-mediated IFNAR1 degradation modulates plasmacytoid dendritic cell interferon-α autoamplification.
Volume: 113
Issue: 5
Pages: 1351-6
Publication
First Author: Baratin M
Year: 2001
Journal: Cancer Gene Ther
Title: Regression of primary hepatocarcinoma in cancer-prone transgenic mice by local interferon-gamma delivery is associated with macrophages recruitment and nitric oxide production.
Volume: 8
Issue: 3
Pages: 193-202
Publication
First Author: Schleicher U
Year: 2004
Journal: Eur J Immunol
Title: Control of Leishmania major in the absence of Tyk2 kinase.
Volume: 34
Issue: 2
Pages: 519-29
Publication
First Author: Malur M
Year: 2012
Journal: J Virol
Title: LGP2 downregulates interferon production during infection with seasonal human influenza A viruses that activate interferon regulatory factor 3.
Volume: 86
Issue: 19
Pages: 10733-8
Publication
First Author: Azuma YT
Year: 2010
Journal: Inflamm Bowel Dis
Title: Interleukin-19 protects mice from innate-mediated colonic inflammation.
Volume: 16
Issue: 6
Pages: 1017-28
Publication  
First Author: Wang Y
Year: 2020
Journal: Front Immunol
Title: HDAC6 Mediates Macrophage iNOS Expression and Excessive Nitric Oxide Production in the Blood During Endotoxemia.
Volume: 11
Pages: 1893
Publication
First Author: McCormack R
Year: 2020
Journal: J Immunol
Title: An Essential Role for Perforin-2 in Type I IFN Signaling.
Volume: 204
Issue: 8
Pages: 2242-2256
Publication
First Author: Radovanovic I
Year: 2014
Journal: J Immunol
Title: Genetic control of susceptibility to Candida albicans in SM/J mice.
Volume: 193
Issue: 3
Pages: 1290-300
Publication
First Author: Bills CJ
Year: 2023
Journal: Emerg Microbes Infect
Title: Mutations in SARS-CoV-2 variant nsp6 enhance type-I interferon antagonism.
Volume: 12
Issue: 1
Pages: 2209208
Publication
First Author: O'Connell P
Year: 2021
Journal: J Immunol
Title: SLAMF7 Signaling Reprograms T Cells toward Exhaustion in the Tumor Microenvironment.
Volume: 206
Issue: 1
Pages: 193-205
Publication
First Author: Hao W
Year: 2023
Journal: Cell Death Dis
Title: Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease.
Volume: 14
Issue: 10
Pages: 680
Publication
First Author: Liu H
Year: 2022
Journal: PLoS Pathog
Title: Free ISG15 inhibits Pseudorabies virus infection by positively regulating type I IFN signaling.
Volume: 18
Issue: 10
Pages: e1010921
Publication  
First Author: Li C
Year: 2022
Journal: Viruses
Title: Interferon-Stimulated Gene 15 Knockout in Mice Impairs IFNα-Mediated Antiviral Activity.
Volume: 14
Issue: 9
Publication
First Author: Zhu J
Year: 2022
Journal: EMBO Rep
Title: LincRNA-EPS impairs host antiviral immunity by antagonizing viral RNA-PKR interaction.
Volume: 23
Issue: 5
Pages: e53937
Publication
First Author: Hao A
Year: 2005
Journal: Mol Biol Cell
Title: The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities.
Volume: 16
Issue: 4
Pages: 1569-83
Publication
First Author: Peng B
Year: 2002
Journal: Mol Endocrinol
Title: CPAP is a novel stat5-interacting cofactor that augments stat5-mediated transcriptional activity.
Volume: 16
Issue: 9
Pages: 2019-33
Publication
First Author: Ma J
Year: 2003
Journal: J Biol Chem
Title: A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation.
Volume: 278
Issue: 31
Pages: 29252-60
Publication
First Author: Dadke S
Year: 2007
Journal: Nat Cell Biol
Title: Regulation of protein tyrosine phosphatase 1B by sumoylation.
Volume: 9
Issue: 1
Pages: 80-5
Publication
First Author: Alblas J
Year: 2005
Journal: Mol Cell Biol
Title: Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways.
Volume: 25
Issue: 16
Pages: 7181-92
Publication
First Author: Dell'Albani P
Year: 2001
Journal: J Neurosci Res
Title: JAK/STAT signaling pathway mediates cytokine-induced iNOS expression in primary astroglial cell cultures.
Volume: 65
Issue: 5
Pages: 417-24
Publication
First Author: Kurtzman AL
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Ubc9 interacts with a nuclear localization signal and mediates nuclear localization of the paired-like homeobox protein Vsx-1 independent of SUMO-1 modification.
Volume: 98
Issue: 10
Pages: 5602-7
Publication
First Author: Briken V
Year: 1995
Journal: Mol Cell Biol
Title: Interferon regulatory factor 1 is required for mouse Gbp gene activation by gamma interferon.
Volume: 15
Issue: 2
Pages: 975-82
Publication
First Author: Azam M
Year: 1995
Journal: EMBO J
Title: Interleukin-3 signals through multiple isoforms of Stat5.
Volume: 14
Issue: 7
Pages: 1402-11