Type |
Details |
Score |
Strain |
Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Trp53/Trp53 |
Background: |
involves: C3H * C57BL/6J * NIH |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Trp53/Trp53 |
Background: |
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Rbx1/Rbx1 |
Background: |
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1a/Cdkn1a Cdkn1b/Cdkn1b |
Background: |
involves: 129S1/Sv * 129S2/SvPas |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ccnd3/Ccnd3 Cdkn1b/Cdkn1b |
Background: |
involves: 129S4/SvJaeSor |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Tg(TG-TPR/NTRK1)#Rstn/? |
Background: |
involves: 129S4/SvJaeSor * C3H * C57BL/6 * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b<+> Tg(TG-TPR/NTRK1)#Rstn/? |
Background: |
involves: 129S4/SvJaeSor * C3H * C57BL/6 * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Kit/Kit |
Background: |
involves: 129S1/Sv * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b<+> Kit/Kit |
Background: |
involves: 129S1/Sv * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Stmn1/Stmn1 |
Background: |
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, targeted mutation, congenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ccnd1/Ccnd1 Cdkn1b/Cdkn1b |
Background: |
involves: 129 * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Nkx3-1/Nkx3-1 |
Background: |
involves: 129S4/SvJaeSor * C57BL/6 * FVB/N |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Tg(KRT5-CDK4)2303Mlrp/? |
Background: |
involves: 129S4/SvJae * C57BL/6 * FVB * SENCAR * SSIN |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Cdkn2c/Cdkn2c |
Background: |
involves: 129/Sv * 129S1/Sv * C57BL/6 * DBA/2 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Men1/Men1<+> |
Background: |
involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1c/Cdkn1c<+> |
Background: |
involves: 129P2/OlaHsd * C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Men1/Men1 |
Background: |
involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1c/Cdkn1c<+> |
Background: |
B6.129P2-Cdkn1c |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b<+> Vsx2/Vsx2 |
Background: |
involves: 129 * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b<+> Ptch1/Ptch1<+> |
Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Ptch1/Ptch1<+> |
Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Fang JS |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. |
Volume: |
8 |
Issue: |
1 |
Pages: |
2149 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qi CF |
Year: |
2006 |
Journal: |
Leuk Res |
Title: |
Expression of the cyclin-dependent kinase inhibitor p27 and its deregulation in mouse B cell lymphomas. |
Volume: |
30 |
Issue: |
2 |
Pages: |
153-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shao J |
Year: |
2015 |
Journal: |
Exp Hematol Oncol |
Title: |
p27(KIP1) and PTEN cooperate in myeloproliferative neoplasm tumor suppression in mice. |
Volume: |
5 |
|
Pages: |
17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suddason T |
Year: |
2016 |
Journal: |
Cell Cycle |
Title: |
Genetic insights into Map3k-dependent proliferative expansion of T cells. |
Volume: |
15 |
Issue: |
15 |
Pages: |
1956-60 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, targeted mutation, transgenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Tg(MMTV-vHaras)SH1Led/? |
Background: |
involves: 129S4/SvJaeSor * C57BL/6J * CD-1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b<+> Crebbp/Crebbp Tg(MMTV-cre)4Mam/? |
Background: |
involves: 129 * C57BL/6 * CBA * FVB |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdk2/Cdk2 Cdk4/Cdk4 Cdkn1b/Cdkn1b |
Background: |
involves: 129S1/Sv * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b Pten/Pten Tg(TPO-cre)1Shk/? |
Background: |
129S1.Cg-Cdkn1b Tg(TPO-cre)1Shk Pten |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b<+> Pten/Pten Tg(TPO-cre)1Shk/? |
Background: |
129S1.Cg-Cdkn1b Tg(TPO-cre)1Shk Pten |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Roumelioti F |
Year: |
2024 |
Journal: |
Elife |
Title: |
Mir221/222 drive synovial hyperplasia and arthritis by targeting cell cycle inhibitors and chromatin remodeling components. |
Volume: |
13 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Emmen JM |
Year: |
2005 |
Journal: |
Endocrinology |
Title: |
In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER){alpha} and ER{beta} null mice indicate a role for ER{beta} in follicular maturation. |
Volume: |
146 |
Issue: |
6 |
Pages: |
2817-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watanabe H |
Year: |
2022 |
Journal: |
JBMR Plus |
Title: |
Transcription Factor Hematopoietically Expressed Homeobox Protein (Hhex) Negatively Regulates Osteoclast Differentiation by Controlling Cyclin-Dependent Kinase Inhibitors. |
Volume: |
6 |
Issue: |
4 |
Pages: |
e10608 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li F |
Year: |
2008 |
Journal: |
Biol Reprod |
Title: |
Involvement of cyclin D3, CDKN1A (p21), and BIRC5 (Survivin) in interleukin 11 stimulation of decidualization in mice. |
Volume: |
78 |
Issue: |
1 |
Pages: |
127-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
An J |
Year: |
2011 |
Journal: |
FASEB J |
Title: |
Krüppel-like factor 4 (KLF4) directly regulates proliferation in thymocyte development and IL-17 expression during Th17 differentiation. |
Volume: |
25 |
Issue: |
10 |
Pages: |
3634-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shizu R |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice. |
Volume: |
8 |
Issue: |
4 |
Pages: |
e61802 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okuda M |
Year: |
1997 |
Journal: |
Gene |
Title: |
Cloning and chromosome mapping of the feline genes p21WAF1 and p27Kip1. |
Volume: |
198 |
Issue: |
1-2 |
Pages: |
141-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith AP |
Year: |
2003 |
Journal: |
Comp Med |
Title: |
Switching of melanocyte pigmentation associated with pituitary pars intermedia tumors in Rb+/- and p27-/- female mice with yellow pelage. |
Volume: |
53 |
Issue: |
1 |
Pages: |
75-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bencivenga D |
Year: |
2017 |
Journal: |
Cancer Lett |
Title: |
p27Kip1 and human cancers: A reappraisal of a still enigmatic protein. |
Volume: |
403 |
|
Pages: |
354-365 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fan L |
Year: |
2020 |
Journal: |
Endocrinology |
Title: |
MiR-221/222 Inhibit Insulin Production of Pancreatic β-Cells in Mice. |
Volume: |
161 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dong W |
Year: |
2022 |
Journal: |
Front Pharmacol |
Title: |
Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome. |
Volume: |
13 |
|
Pages: |
783706 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ccnd3/Ccnd3 Cdkn1b/Cdkn1b Rb1/Rb1 Tg(Mx1-cre)1Cgn/? |
Background: |
involves: 129S4/SvJaeSor * C57BL/6 * CBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cdkn1b/Cdkn1b<+> Plekha5/? Pum1/Pum1 |
Background: |
involves: 129 * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Sachdeva R |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Transgenesis-mediated reproductive dysfunction and tumorigenesis: effects of immunological neutralization. |
Volume: |
7 |
Issue: |
11 |
Pages: |
e51125 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wiedemann T |
Year: |
2016 |
Journal: |
Mol Cell Endocrinol |
Title: |
Animal models of multiple endocrine neoplasia. |
Volume: |
421 |
|
Pages: |
49-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo Y |
Year: |
2019 |
Journal: |
Gastroenterology |
Title: |
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6. |
Volume: |
157 |
Issue: |
3 |
Pages: |
744-759.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le JA |
Year: |
2012 |
Journal: |
Biol Reprod |
Title: |
Generation of mice expressing only the long form of the prolactin receptor reveals that both isoforms of the receptor are required for normal ovarian function. |
Volume: |
86 |
Issue: |
3 |
Pages: |
86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
221
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Function or Process or Component Unknown following Literature Review |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY) |
Year: |
2005 |
Journal: |
Database Download |
Title: |
MGI download of GENSAT transgene data |
|
|
|
|
•
•
•
•
•
|