| Type |
Details |
Score |
| ncRNA Gene |
| Type: |
ncRNA_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| ncRNA Gene |
| Type: |
ncRNA_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| ncRNA Gene |
| Type: |
ncRNA_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| ncRNA Gene |
| Type: |
ncRNA_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| ncRNA Gene |
| Type: |
ncRNA_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6473344 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3574128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6476702 |
| Age: |
postnatal week 14 |
| Image: |
7b left |
| Note: |
Coexpressed with Chat in starburst amacrines. |
| Specimen Label: |
7b left |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6473344 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1915528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6476702 |
| Age: |
postnatal week 14 |
| Image: |
7b left |
| Note: |
Coexpressed with Chat in starburst amacrines. |
| Specimen Label: |
7b left |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6473344 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3573928 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6476702 |
| Age: |
postnatal week 14 |
| Image: |
7b left |
| Note: |
Coexpressed with Chat in starburst amacrines. |
| Specimen Label: |
7b left |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 2, Michael I Kotlikoff |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Collin T |
| Year: |
2005 |
| Journal: |
J Neurosci |
| Title: |
Developmental changes in parvalbumin regulate presynaptic Ca2+ signaling. |
| Volume: |
25 |
| Issue: |
1 |
| Pages: |
96-107 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5646162 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2017-12-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716828 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6099125 |
| Age: |
postnatal adult |
| Image: |
4N |
| Note: |
Authors report co-localization with Chat in most starburst amacrine cells. |
| Specimen Label: |
4N |
| Detected: |
true |
| Specimen Num: |
40 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7427775 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7427794 |
| Age: |
postnatal adult |
| Image: |
2A,B,D |
| Note: |
Expression co-localized with that of Chat in spinal motor neurons. |
| Specimen Label: |
2A,B,D |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
854
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Transgene |
| Type: |
transgene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7450795 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3538622 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7450905 |
| Age: |
embryonic day 14.5 |
| Image: |
6K |
| Note: |
Nwd2 was expressed in the habenula earlier than Chat labeling was detected. |
| Specimen Label: |
6K |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5780337 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2016-07-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187820 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:5780425 |
| Age: |
embryonic day 12.5 |
|
| Note: |
Expression in small pockets of chat appear to be trophoblast glycogen cells. |
| Specimen Label: |
Day 12 placental labyrinth |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7450795 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3554728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7450905 |
| Age: |
postnatal day 14 |
| Image: |
6N |
| Note: |
Expression in the ventral medial habenula overlapped with Chat expression in cholinergic neurons. |
| Specimen Label: |
6N |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7450795 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3554728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7450905 |
| Age: |
postnatal day 14 |
| Image: |
6N |
| Note: |
Expression of Nwd2 in dorsal medial habenula was devoid of Chat expression. |
| Specimen Label: |
6N |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7450795 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3554728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7450905 |
| Age: |
postnatal adult |
| Image: |
6Q |
| Note: |
Expression in the ventral medial habenula overlapped with Chat expression in cholinergic neurons. |
| Specimen Label: |
6Q |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7450795 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-04-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3554728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7450905 |
| Age: |
postnatal adult |
| Image: |
6Q |
| Note: |
Expression of Nwd2 in dorsal medial habenula was devoid of Chat expression. |
| Specimen Label: |
6Q |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7709272 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-08-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3704921 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:7709294 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Co-expression with Chat RNA in motor neurons in wild type embryos. |
| Specimen Label: |
5c |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Allele |
| Name: |
choline O-acetyltransferase; targeted mutation 1, Fred H Gage |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
choline O-acetyltransferase; targeted mutation 1.1, Joshua R Sanes |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159039 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164673 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with all. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159082 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164676 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with all. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159150 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164659 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP, Calb1 and Nos1 and partial co-expression with Npy and CHaT. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159113 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164668 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP, Calb1 and Nos1 and partial co-expression with Npy and CHaT. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159162 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164711 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and CGRP and partial co-expression with Calb1, Nos1, Npy and CHaT. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159059 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164678 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP, Calb1 and NPY and partial co-expression with Nos1 and CHaT. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159107 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164658 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP and NPY and partial co-expression with Calb1, Nos1 and CHaT. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159047 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164653 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP and NPY and partial co-expression with Calb1, Nos1 and CHaT. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5760020 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164657 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, no co-expression with CGRP, and partial-coexpression with the rest. |
| Specimen Label: |
Table 3B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159152 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164660 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with NPY and partial co-expression with the rest. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159084 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164661 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and NPY and partial co-expression with the rest. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159139 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164664 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and NPY and partial co-expression with the rest. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159111 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164667 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with CGRP and NPY and partial co-expression with the rest. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159115 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164670 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and NPY and partial co-expression with the rest. |
| Specimen Label: |
Table 3A |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Chat/Chat |
| Background: |
involves: 129S2/SvPas * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Chat/Chat |
| Background: |
Not Specified |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Allele |
| Name: |
choline O-acetyltransferase; endonuclease-mediated mutation 1,Bradford B Lowell |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
choline O-acetyltransferase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159099 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164656 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, partial co-expression with Nos1 and CHaT and no co-expression with the rest. |
| Specimen Label: |
Table 3B |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159109 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164666 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and CGRP, partial co-expression with Nos1 and CHaT and no co-expression with Calb1 and NPY. |
| Specimen Label: |
Table 3B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2677714 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164669 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th, CGRP, Calb1 and NPY, partial co-expression with CHaT and no co-expression with Nos1. |
| Specimen Label: |
Table 3B |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159056 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6164674 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with CGRP, Calb1 and NPY, partial co-expression with Nos1 and CHaT and no co-expression with Th. |
| Specimen Label: |
Table 3B |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159063 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6189228 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and CGRP, partial co-expression with Nos1 and CHaT and no co-expression with Calb1 and NPY. |
| Specimen Label: |
Table 3B |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159063 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6189229 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and CGRP, partial co-expression with Nos1 and CHaT and no co-expression with Calb1 and NPY. |
| Specimen Label: |
Table 3B |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6159063 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-07-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2692226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6189230 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Co-expression analysis was done with neurotransmitters and neuropeptides: TH, NPY and ChAT (in the stomach) and CGRP, Calb1, and Nos1 (in the small intestine). Co-expression was seen with Th and CGRP, partial co-expression with Nos1 and CHaT and no co-expression with Calb1 and NPY. |
| Specimen Label: |
Table 3B |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion SZ28, GENSAT Project at Rockefeller University |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Hannah Monyer |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yi F |
| Year: |
2015 |
| Journal: |
Front Synaptic Neurosci |
| Title: |
Hippocampal "cholinergic interneurons" visualized with the choline acetyltransferase promoter: anatomical distribution, intrinsic membrane properties, neurochemical characteristics, and capacity for cholinergic modulation. |
| Volume: |
7 |
|
| Pages: |
4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Perez-Medina AL |
| Year: |
2019 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Optogenetic analysis of neuromuscular transmission in the colon of ChAT-ChR2-YFP BAC transgenic mice. |
| Volume: |
317 |
| Issue: |
5 |
| Pages: |
G569-G579 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cui LJ |
| Year: |
2020 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
nGnG Amacrine Cells and Brn3b-negative M1 ipRGCs are Specifically Labeled in the ChAT-ChR2-EYFP Mouse. |
| Volume: |
61 |
| Issue: |
2 |
| Pages: |
14 |
|
•
•
•
•
•
|
| Allele |
| Name: |
choline O-acetyltransferase; targeted mutation 1, Bradford B Lowell |
| Allele Type: |
Targeted |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion GM24, GENSAT Project at Rockefeller University |
| Allele Type: |
Transgenic |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, transgenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transgenic, mutant stock |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hu R |
| Year: |
2016 |
| Journal: |
Front Neuroanat |
| Title: |
Whole-Brain Monosynaptic Afferent Inputs to Basal Forebrain Cholinergic System. |
| Volume: |
10 |
|
| Pages: |
98 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schlamp CL |
| Year: |
2013 |
| Journal: |
Mol Vis |
| Title: |
Evaluation of the percentage of ganglion cells in the ganglion cell layer of the rodent retina. |
| Volume: |
19 |
|
| Pages: |
1387-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Witten IB |
| Year: |
2010 |
| Journal: |
Science |
| Title: |
Cholinergic interneurons control local circuit activity and cocaine conditioning. |
| Volume: |
330 |
| Issue: |
6011 |
| Pages: |
1677-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bensussen S |
| Year: |
2020 |
| Journal: |
iScience |
| Title: |
A Viral Toolbox of Genetically Encoded Fluorescent Synaptic Tags. |
| Volume: |
23 |
| Issue: |
7 |
| Pages: |
101330 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Won L |
| Year: |
2014 |
| Journal: |
J Neurosci |
| Title: |
Striatal cholinergic cell ablation attenuates L-DOPA induced dyskinesia in Parkinsonian mice. |
| Volume: |
34 |
| Issue: |
8 |
| Pages: |
3090-4 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transgenic, mutant stock |
|
•
•
•
•
•
|
| Allele |
| Name: |
choline O-acetyltransferase; targeted mutation 2, Bradford B Lowell |
| Allele Type: |
Targeted |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion DW167, Nathaniel Heintz |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, Sukumar Vijayaraghavan |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Publication |
| First Author: |
von Engelhardt J |
| Year: |
2007 |
| Journal: |
J Neurosci |
| Title: |
Functional characterization of intrinsic cholinergic interneurons in the cortex. |
| Volume: |
27 |
| Issue: |
21 |
| Pages: |
5633-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schütz B |
| Year: |
2008 |
| Journal: |
Neuroscience |
| Title: |
Sweat gland innervation is pioneered by sympathetic neurons expressing a cholinergic/noradrenergic co-phenotype in the mouse. |
| Volume: |
156 |
| Issue: |
2 |
| Pages: |
310-8 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 22, Marthe Howard |
| Allele Type: |
Transgenic |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dhanasobhon D |
| Year: |
2021 |
| Journal: |
Neurobiol Dis |
| Title: |
Enhanced analgesic cholinergic tone in the spinal cord in a mouse model of neuropathic pain. |
| Volume: |
155 |
|
| Pages: |
105363 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gritton HJ |
| Year: |
2019 |
| Journal: |
Nat Neurosci |
| Title: |
Unique contributions of parvalbumin and cholinergic interneurons in organizing striatal networks during movement. |
| Volume: |
22 |
| Issue: |
4 |
| Pages: |
586-597 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zemel D |
| Year: |
2022 |
| Journal: |
Cell Rep |
| Title: |
Dopamine depletion selectively disrupts interactions between striatal neuron subtypes and LFP oscillations. |
| Volume: |
38 |
| Issue: |
3 |
| Pages: |
110265 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, mutant stock |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, targeted mutation, congenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, transgenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Görlich A |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Reexposure to nicotine during withdrawal increases the pacemaking activity of cholinergic habenular neurons. |
| Volume: |
110 |
| Issue: |
42 |
| Pages: |
17077-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grybko MJ |
| Year: |
2011 |
| Journal: |
Eur J Neurosci |
| Title: |
A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons. |
| Volume: |
33 |
| Issue: |
10 |
| Pages: |
1786-98 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Chat/? |
| Background: |
involves: 129S6/SvEvTac |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yung KK |
| Year: |
1994 |
| Journal: |
Brain Res |
| Title: |
Alterations in acetylcholinesterase and choline acetyltransferase activities and neuropeptide levels in the ventral spinal cord of the Wobbler mouse during inherited motoneuron disease. |
| Volume: |
638 |
| Issue: |
1-2 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yeo TT |
| Year: |
1997 |
| Journal: |
J Neurosci |
| Title: |
Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation. |
| Volume: |
17 |
| Issue: |
20 |
| Pages: |
7594-605 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reardon C |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Lymphocyte-derived ACh regulates local innate but not adaptive immunity. |
| Volume: |
110 |
| Issue: |
4 |
| Pages: |
1410-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Azzouz M |
| Year: |
1999 |
| Journal: |
Neuroreport |
| Title: |
Compensatory mechanism of motor defect in SOD1 transgenic mice by overactivation of striatal cholinergic neurons. |
| Volume: |
10 |
| Issue: |
5 |
| Pages: |
1013-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Perez SE |
| Year: |
2007 |
| Journal: |
Neurobiol Dis |
| Title: |
Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse. |
| Volume: |
28 |
| Issue: |
1 |
| Pages: |
3-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yuan Y |
| Year: |
2013 |
| Journal: |
Neurosci Lett |
| Title: |
Mef2 promotes spine elimination in absence of δ-catenin. |
| Volume: |
536 |
|
| Pages: |
10-3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Calvo-Enrique L |
| Year: |
2023 |
| Journal: |
Front Mol Neurosci |
| Title: |
Enhanced TrkA signaling impairs basal forebrain-dependent behavior. |
| Volume: |
16 |
|
| Pages: |
1266983 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
AlQot HE |
| Year: |
2024 |
| Journal: |
Sci Rep |
| Title: |
Primate-specific 82-kDa choline acetyltransferase attenuates progression of Alzheimer's disease-like pathology in the APP(NL-G-F) knock-in mouse model. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
27614 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li LZ |
| Year: |
2019 |
| Journal: |
Neurosci Bull |
| Title: |
Rac1 Modulates Excitatory Synaptic Transmission in Mouse Retinal Ganglion Cells. |
| Volume: |
35 |
| Issue: |
4 |
| Pages: |
673-687 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang ML |
| Year: |
2020 |
| Journal: |
Cell Death Dis |
| Title: |
Rac1 conditional deletion attenuates retinal ganglion cell apoptosis by accelerating autophagic flux in a mouse model of chronic ocular hypertension. |
| Volume: |
11 |
| Issue: |
9 |
| Pages: |
734 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion A, Hidemi Misawa |
| Allele Type: |
Transgenic |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion K, Hidemi Misawa |
| Allele Type: |
Transgenic |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, Hidemi Misawa |
| Allele Type: |
Transgenic |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lewis RG |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
Dopaminergic Control of Striatal Cholinergic Interneurons Underlies Cocaine-Induced Psychostimulation. |
| Volume: |
31 |
| Issue: |
3 |
| Pages: |
107527 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kharkwal G |
| Year: |
2016 |
| Journal: |
Neuron |
| Title: |
Parkinsonism Driven by Antipsychotics Originates from Dopaminergic Control of Striatal Cholinergic Interneurons. |
| Volume: |
91 |
| Issue: |
1 |
| Pages: |
67-78 |
|
•
•
•
•
•
|