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Search results 1501 to 1600 out of 2260 for Erbb2

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Type Details Score
Allele
Name: transgene insertion NYPD10, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion NYPD11, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion YB2, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion YB6, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion YD5, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion YD6, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion YC, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion YE4, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion YE7, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion YE, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Cheng X
Year: 2023
Journal: Cancer Res
Title: Breast Cancer Mutations HER2V777L and PIK3CAH1047R Activate the p21-CDK4/6-Cyclin D1 Axis to Drive Tumorigenesis and Drug Resistance.
Volume: 83
Issue: 17
Pages: 2839-2857
Publication  
First Author: Wang J
Year: 2022
Journal: Cancers (Basel)
Title: HER2-Displaying M13 Bacteriophages induce Therapeutic Immunity against Breast Cancer.
Volume: 14
Issue: 16
Publication
First Author: Castagnoli L
Year: 2014
Journal: Cancer Res
Title: Activated d16HER2 homodimers and SRC kinase mediate optimal efficacy for trastuzumab.
Volume: 74
Issue: 21
Pages: 6248-59
Genotype
Symbol: Tg(MMTVneu)202Mul/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Erbb2/Erbb2<+> Erbb3/Erbb3<+> Nrg1/Nrg1<+>
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTVneu)202Mul/?
Background: FVB/N-Tg(MMTVneu)202Mul
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Erbb2/Erbb2<+> Tg(MMTV-cre)7Mul/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTV-Erbb2)NK1Mul/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTV-Erbb2)NK1Mul/Tg(MMTV-Erbb2)NK1Mul
Background: involves: 129 * C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Erbb2/Erbb2<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Erbb2/Erbb2
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Shc1/Shc1 Tg(MMTV-Erbb2*,-cre)1Mul/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTV-Erbb2)NK1Mul/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Stk11/Stk11 Tg(MMTV-Erbb2*,-cre)1Mul/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTV-Erbb2)NK1Mul/?
Background: FVB/N-Tg(MMTV-Erbb2)NK1Mul
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Rossi C
Year: 2008
Journal: Eur J Cancer
Title: Intestinal tumour chemoprevention with the antioxidant lipoic acid stimulates the growth of breast cancer.
Volume: 44
Issue: 17
Pages: 2696-704
Publication
First Author: Su S
Year: 2018
Journal: Cell
Title: Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages.
Volume: 175
Issue: 2
Pages: 442-457.e23
Publication  
First Author: Podsypanina K
Year: 2004
Journal: BMC Med
Title: Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype.
Volume: 2
Pages: 24
Publication
First Author: McLaughlin SK
Year: 2013
Journal: Cancer Cell
Title: The RasGAP gene, RASAL2, is a tumor and metastasis suppressor.
Volume: 24
Issue: 3
Pages: 365-78
Publication
First Author: Vaillant F
Year: 2008
Journal: Cancer Res
Title: The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis.
Volume: 68
Issue: 19
Pages: 7711-7
Publication
First Author: Rajkumar L
Year: 2007
Journal: Breast Cancer Res
Title: Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models.
Volume: 9
Issue: 1
Pages: R12
Publication
First Author: Wu X
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.
Volume: 111
Issue: 38
Pages: 13870-5
Publication
First Author: Subbaramaiah K
Year: 2006
Journal: Cancer Res
Title: HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism.
Volume: 66
Issue: 10
Pages: 5504-11
Publication
First Author: Jeong J
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer.
Volume: 113
Issue: 3
Pages: E282-90
Publication
First Author: Facciponte JG
Year: 2007
Journal: Eur J Immunol
Title: Hsp110 and Grp170, members of the Hsp70 superfamily, bind to scavenger receptor-A and scavenger receptor expressed by endothelial cells-I.
Volume: 37
Issue: 8
Pages: 2268-79
Publication
First Author: Ciampricotti M
Year: 2011
Journal: J Pathol
Title: Development of metastatic HER2(+) breast cancer is independent of the adaptive immune system.
Volume: 224
Issue: 1
Pages: 56-66
Publication  
First Author: Sangaletti S
Year: 2019
Journal: Front Immunol
Title: SPARC Is a New Myeloid-Derived Suppressor Cell Marker Licensing Suppressive Activities.
Volume: 10
Pages: 1369
Strain
Attribute String: mutant strain, transgenic
Strain
Attribute String: congenic, transgenic
Publication
First Author: Pannellini T
Year: 2006
Journal: J Immunol
Title: Timely DNA vaccine combined with systemic IL-12 prevents parotid carcinomas before a dominant-negative p53 makes their growth independent of HER-2/neu expression.
Volume: 176
Issue: 12
Pages: 7695-703
Strain
Attribute String: mutant strain, transgenic
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Publication
First Author: Liu S
Year: 2018
Journal: Cancer Res
Title: HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance.
Volume: 78
Issue: 8
Pages: 2040-2051
Publication
First Author: Spiotto MT
Year: 2010
Journal: Cancer Res
Title: Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth.
Volume: 70
Issue: 1
Pages: 78-88
Publication
First Author: La Merrill M
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat.
Volume: 296
Issue: 1
Pages: E203-10
Publication
First Author: Youngblood VM
Year: 2016
Journal: Cancer Res
Title: The Ephrin-A1/EPHA2 Signaling Axis Regulates Glutamine Metabolism in HER2-Positive Breast Cancer.
Volume: 76
Issue: 7
Pages: 1825-36
Publication
First Author: Hannesdóttir L
Year: 2013
Journal: Eur J Immunol
Title: Lapatinib and doxorubicin enhance the Stat1-dependent antitumor immune response.
Volume: 43
Issue: 10
Pages: 2718-29
Publication
First Author: Rennhack JP
Year: 2019
Journal: Nat Commun
Title: Integrated analyses of murine breast cancer models reveal critical parallels with human disease.
Volume: 10
Issue: 1
Pages: 3261
Publication
First Author: Heckman-Stoddard BM
Year: 2009
Journal: Breast Cancer Res
Title: Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression.
Volume: 11
Issue: 4
Pages: R61
Publication
First Author: Boggio K
Year: 2000
Journal: Cancer Res
Title: Ability of systemic interleukin-12 to hamper progressive stages of mammary carcinogenesis in HER2/neu transgenic mice.
Volume: 60
Issue: 2
Pages: 359-64
Publication
First Author: Di Carlo E
Year: 1999
Journal: Lab Invest
Title: Analysis of mammary carcinoma onset and progression in HER-2/neu oncogene transgenic mice reveals a lobular origin.
Volume: 79
Issue: 10
Pages: 1261-9
Publication
First Author: Quaglino E
Year: 2010
Journal: Cancer Res
Title: A better immune reaction to Erbb-2 tumors is elicited in mice by DNA vaccines encoding rat/human chimeric proteins.
Volume: 70
Issue: 7
Pages: 2604-12
Publication
First Author: Srijakotre N
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis.
Volume: 117
Issue: 45
Pages: 28056-28067
Publication
First Author: Rudolph-Owen LA
Year: 1998
Journal: Cancer Res
Title: The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis.
Volume: 58
Issue: 23
Pages: 5500-6
Publication
First Author: De Lorenzo MS
Year: 2014
Journal: Aging Cell
Title: 'Reduced malignancy as a mechanism for longevity in mice with adenylyl cyclase type 5 disruption'.
Volume: 13
Issue: 1
Pages: 102-10
Publication
First Author: Hannesdóttir L
Year: 2012
Journal: Int J Dev Biol
Title: MMTV-neu mice deficient in STAT1 are susceptible to develop ovarian teratomas.
Volume: 56
Issue: 4
Pages: 279-83
Publication
First Author: Balamurugan K
Year: 2010
Journal: EMBO J
Title: The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis.
Volume: 29
Issue: 24
Pages: 4106-17
Publication
First Author: Lenferink AE
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice.
Volume: 97
Issue: 17
Pages: 9609-14
Publication
First Author: Cardiff RD
Year: 1995
Journal: Cancer Lett
Title: Comparative pathology of mammary tumorigenesis in transgenic mice.
Volume: 90
Issue: 1
Pages: 13-9
Publication
First Author: Laine A
Year: 2013
Journal: Cancer Discov
Title: Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.
Volume: 3
Issue: 2
Pages: 182-97
Publication
First Author: Lee S
Year: 2018
Journal: Oncogene
Title: Na+,HCO3--cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice.
Volume: 37
Issue: 41
Pages: 5569-5584
Publication
First Author: Chiodoni C
Year: 2006
Journal: J Exp Med
Title: Triggering CD40 on endothelial cells contributes to tumor growth.
Volume: 203
Issue: 11
Pages: 2441-50
Publication
First Author: Ritland SR
Year: 1997
Journal: Cancer Res
Title: Loss of heterozygosity analysis in primary mammary tumors and lung metastases of MMTV-MTAg and MMTV-neu transgenic mice.
Volume: 57
Issue: 16
Pages: 3520-5
Publication
First Author: Little JL
Year: 2014
Journal: Oncogene
Title: A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice.
Volume: 33
Issue: 4
Pages: 411-20
Publication
First Author: Hüsemann Y
Year: 2008
Journal: Cancer Cell
Title: Systemic spread is an early step in breast cancer.
Volume: 13
Issue: 1
Pages: 58-68
Publication
First Author: Saha A
Year: 2010
Journal: Cell Immunol
Title: Dendritic cells pulsed with an anti-idiotype antibody mimicking Her-2/neu induced protective antitumor immunity in two lines of Her-2/neu transgenic mice.
Volume: 263
Issue: 1
Pages: 9-21
Publication  
First Author: Balamurugan K
Year: 2013
Journal: Nat Commun
Title: FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.
Volume: 4
Pages: 1662
Publication
First Author: Nørgaard P
Year: 1999
Journal: Clin Cancer Res
Title: Treatment with farnesyl-protein transferase inhibitor induces regression of mammary tumors in transforming growth factor (TGF) alpha and TGF alpha/neu transgenic mice by inhibition of mitogenic activity and induction of apoptosis.
Volume: 5
Issue: 1
Pages: 35-42
Publication
First Author: Boggio K
Year: 1998
Journal: J Exp Med
Title: Interleukin 12-mediated prevention of spontaneous mammary adenocarcinomas in two lines of Her-2/neu transgenic mice.
Volume: 188
Issue: 3
Pages: 589-96
Publication
First Author: Yang Y
Year: 2021
Journal: Cell Rep
Title: Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer.
Volume: 34
Issue: 10
Pages: 108822
Publication
First Author: Taneja P
Year: 2010
Journal: Cancer Res
Title: Critical roles of DMP1 in human epidermal growth factor receptor 2/neu-Arf-p53 signaling and breast cancer development.
Volume: 70
Issue: 22
Pages: 9084-94
Publication
First Author: Kim S
Year: 2012
Journal: PLoS One
Title: A phenotypic mouse model of basaloid breast tumors.
Volume: 7
Issue: 2
Pages: e30979
Publication
First Author: Asrani K
Year: 2013
Journal: Mol Cancer Res
Title: The HER2- and heregulin β1 (HRG)-inducible TNFR superfamily member Fn14 promotes HRG-driven breast cancer cell migration, invasion, and MMP9 expression.
Volume: 11
Issue: 4
Pages: 393-404
Publication
First Author: Niemeyer CC
Year: 1999
Journal: Int J Cancer
Title: Preneoplastic mammary tumor markers: Cripto and Amphiregulin are overexpressed in hyperplastic stages of tumor progression in transgenic mice.
Volume: 81
Issue: 4
Pages: 588-91
Publication
First Author: Tracey N
Year: 2020
Journal: Breast Cancer Res Treat
Title: HO-1 drives autophagy as a mechanism of resistance against HER2-targeted therapies.
Volume: 179
Issue: 3
Pages: 543-555
Publication
First Author: Levi L
Year: 2013
Journal: Cancer Res
Title: Genetic ablation of the fatty acid-binding protein FABP5 suppresses HER2-induced mammary tumorigenesis.
Volume: 73
Issue: 15
Pages: 4770-80
Publication
First Author: Miller AV
Year: 2013
Journal: PLoS One
Title: Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.
Volume: 8
Issue: 4
Pages: e60685
Publication
First Author: Lehembre F
Year: 2008
Journal: EMBO J
Title: NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherin.
Volume: 27
Issue: 19
Pages: 2603-15
Publication
First Author: Leng X
Year: 2009
Journal: Cancer Res
Title: Inhibition of lipocalin 2 impairs breast tumorigenesis and metastasis.
Volume: 69
Issue: 22
Pages: 8579-84
Publication  
First Author: Deblois G
Year: 2016
Journal: Nat Commun
Title: ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer.
Volume: 7
Pages: 12156
Publication
First Author: Jacob JB
Year: 2023
Journal: iScience
Title: Identification of actionable targets for breast cancer intervention using a diversity outbred mouse model.
Volume: 26
Issue: 4
Pages: 106320
Publication
First Author: Huo Y
Year: 2016
Journal: Cell Rep
Title: An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter.
Volume: 15
Issue: 10
Pages: 2089-2096
Allele
Name: transgene insertion, Joaquin Arribas
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Genotype
Symbol: Erbb2/Erbb2 Tg(ACTA1-cre)1Mll/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Egr2/Egr2<+> Erbb2/Erbb2
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdc25a/Cdc25a<+> Tg(MMTV-Erbb2)NK1Mul/?
Background: involves: 129/Sv * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTVneu)202Mul/? Tg(Trp53R172H)8512Jmr/?
Background: C.FVB-Tg(MMTVneu)202Mul Tg(Trp53R172H)8512Jmr
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTVneu)202Mul/? Tg(Trp53R172H)8512Jmr/?
Background: involves: FVB
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTVneu)202Mul/? Tg(MMTVTGFA)29Rjc/?
Background: involves: C57BL/6 * DBA/2 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Akt1/Akt1 Tg(MMTV-Erbb2)NK1Mul/Tg(MMTV-Erbb2)NK1Mul
Background: involves: 129 * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Stat1/Stat1 Tg(MMTV-Erbb2*,-cre)1Mul/?
Background: involves: 129S/SvEv * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(MMTV-Erbb2*)NDL2-5Mul/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Rasal2/Rasal2 Tg(MMTVneu)202Mul/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Mtdh/Mtdh Tg(MMTVneu)202Mul/?
Background: FVB.Cg-Mtdh Tg(MMTVneu)202Mul
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Huang P
Year: 2024
Journal: Cell Host Microbe
Title: Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK.
Volume: 32
Issue: 8
Pages: 1365-1379.e10
Publication
First Author: He J
Year: 2023
Journal: Sci Adv
Title: Inactivation of the tumor suppressor gene Apc synergizes with H. pylori to induce DNA damage in murine gastric stem and progenitor cells.
Volume: 9
Issue: 46
Pages: eadh0322
Publication
First Author: Grossmann KS
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development.
Volume: 106
Issue: 39
Pages: 16704-9
Publication
First Author: Muta Y
Year: 2018
Journal: Nat Commun
Title: Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine.
Volume: 9
Issue: 1
Pages: 2174
Publication
First Author: Meyer D
Year: 1995
Journal: Nature
Title: Multiple essential functions of neuregulin in development.
Volume: 378
Issue: 6555
Pages: 386-90
Publication
First Author: Fledrich R
Year: 2019
Journal: Nat Commun
Title: NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies.
Volume: 10
Issue: 1
Pages: 1467