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Search results 1501 to 1600 out of 1990 for Gk

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Type Details Score
Publication
27422518 | J:244707
First Author: Bachmanov AA
Year: 2016
Journal: Adv Nutr
Title: Genetics of Amino Acid Taste and Appetite.
Volume: 7
Issue: 4
Pages: 806S-22S
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Publication
28866049 | J:252262
 
First Author: Rodrigues BA
Year: 2017
Journal: Neurosci Lett
Title: Overexpression of Mitogen-activated protein kinase phosphatase-3 (MKP-3) reduces FoxO1 phosphorylation in mice hypothalamus.
Volume: 659
Pages: 14-17
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Publication
29158510 | J:360312
First Author: Pal B
Year: 2017
Journal: Nat Commun
Title: Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling.
Volume: 8
Issue: 1
Pages: 1627
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Publication
28966122 | J:255088
First Author: Harikumar A
Year: 2017
Journal: Stem Cell Reports
Title: An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells.
Volume: 9
Issue: 4
Pages: 1304-1314
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Publication
29380422 | J:258725
First Author: Meares GP
Year: 2018
Journal: Glia
Title: MicroRNA-31 is required for astrocyte specification.
Volume: 66
Issue: 5
Pages: 987-998
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Publication
30661928 | J:274688
First Author: Ericksen RE
Year: 2019
Journal: Cell Metab
Title: Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression.
Volume: 29
Issue: 5
Pages: 1151-1165.e6
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Publication
31727780 | J:285062
 
First Author: du Pré MF
Year: 2020
Journal: J Exp Med
Title: B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2.
Volume: 217
Issue: 2
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Publication
32029227 | J:285388
 
First Author: Barnes TM
Year: 2020
Journal: Mol Metab
Title: Identification of the leptin receptor sequences crucial for the STAT3-Independent control of metabolism.
Volume: 32
Pages: 168-175
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Publication
31393851 | J:293785
First Author: Kumar D
Year: 2019
Journal: J Clin Invest
Title: Degradation of splicing factor SRSF3 contributes to progressive liver disease.
Volume: 129
Issue: 10
Pages: 4477-4491
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Publication
30613274 | J:295646
First Author: Li X
Year: 2018
Journal: Theranostics
Title: Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice.
Volume: 8
Issue: 21
Pages: 5960-5971
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Publication
32989093 | J:303629
First Author: de Barros SC
Year: 2020
Journal: J Immunol
Title: Pleiotropic Roles of VEGF in the Microenvironment of the Developing Thymus.
Volume: 205
Issue: 9
Pages: 2423-2436
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Publication
36824462 | J:361243
 
First Author: Warwick T
Year: 2023
Journal: Front Physiol
Title: Acute injury to the mouse carotid artery provokes a distinct healing response.
Volume: 14
Pages: 1125864
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Publication
28115703 | J:341751
First Author: Peng YJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Complementary roles of gasotransmitters CO and H2S in sleep apnea.
Volume: 114
Issue: 6
Pages: 1413-1418
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Publication
36920307 | J:340628
 
First Author: Abdulla HD
Year: 2023
Journal: J Exp Med
Title: Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition.
Volume: 220
Issue: 6
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Publication
34187545 | J:356125
First Author: Pal B
Year: 2021
Journal: Breast Cancer Res
Title: Single cell transcriptome atlas of mouse mammary epithelial cells across development.
Volume: 23
Issue: 1
Pages: 69
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Publication
23969857 | -
 
First Author: Khedgikar V
Year: 2013
Journal: Cell Death Dis
Title: Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone.
Volume: 4
Pages: e778
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Publication
1350780 | -
First Author: Li W
Year: 1992
Journal: J Bacteriol
Title: Proline biosynthesis in Saccharomyces cerevisiae: molecular analysis of the PRO1 gene, which encodes gamma-glutamyl kinase.
Volume: 174
Issue: 12
Pages: 4148-56
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Protein Domain
IPR005417 | ZO
Type: Family
Description: The zona occuldens proteins (ZO-1, ZO-2 and ZO-3) are a family of TJ- associated proteins that function as cross-linkers, anchoring the TJ strand proteins to the actin-based cytoskeleton []. Each protein contains three PDZ (postsynaptic density, disc-large, ZO-1) domains, a single SH3 (Src Homology-3) domain and a GK (guanylate kinase) domain, the presence of whichidentifies them as members of the membrane-associated guanylate kinase (MAGUK) protein family. They also share an acidic domain at the C-terminal region of the molecules not found in other MAGUK proteins. It has been demonstrated that the first PDZ domain is involved in binding the C-terminal-Y-V motif of claudins []. By contrast, the occludin-binding domain ofZO-1 has been shown to lie in the GK and acidic domains []. Although the precise location of the actin-binding motif has not been elucidated, it appears to be within the C-terminal half of the molecules, since transfection of this region into fibroblasts induces co-localisation of ZO-1 and ZO-2 with actin fibres.
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Protein Domain
IPR008145 | GK/Ca_channel_bsu
Type: Domain
Description: This entry represents a domain found in guanylate kinase () and in L-type calcium channel.Guanylate kinase () (GK) []catalyzes the ATP-dependent phosphorylation of GMP into GDP. It is essential for recycling GMP and indirectly, cGMP. In prokaryotes (such as Escherichia coli), lower eukaryotes(such as yeast) and in vertebrates, GK is a highly conserved monomeric protein of about 200 amino acids. GK has been shown [, , ]to be structurally similar to protein A57R (or SalG2R) from various strains of Vaccinia virus.L-type calcium channnels are formed from different alpha-1 subunit isoforms that determine the pharmacological properties of the channel, since they form the drug binding domain. Other properties, such as gating voltage-dependence, G protein modulation and kinase susceptibility, are influenced by alpha-2, delta and beta subunits.
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Publication
141272 | J:5824
First Author: Coleman DL
Year: 1977
Journal: Biochem Genet
Title: Genetic control of glucokinase activity in mice.
Volume: 15
Issue: 3-4
Pages: 297-305
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HT Experiment
E-GEOD-12748 | Weighted Gene Coexpression Network Analysis Identifies Biomarkers in Glycerol Kinase Deficient Mice
Series Id: GSE12748
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
26803617 | J:230816
First Author: Diener S
Year: 2016
Journal: Mamm Genome
Title: Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia.
Volume: 27
Issue: 3-4
Pages: 111-21
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Publication
15650770 | J:95952
First Author: Angelillo-Scherrer A
Year: 2005
Journal: J Clin Invest
Title: Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.
Volume: 115
Issue: 2
Pages: 237-46
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Publication
10783391 | J:70880
First Author: Board PG
Year: 2000
Journal: J Biol Chem
Title: Identification, characterization, and crystal structure of the Omega class glutathione transferases.
Volume: 275
Issue: 32
Pages: 24798-806
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Publication
24462369 | -
First Author: Lim SC
Year: 2014
Journal: Am J Hum Genet
Title: A founder mutation in PET100 causes isolated complex IV deficiency in Lebanese individuals with Leigh syndrome.
Volume: 94
Issue: 2
Pages: 209-22
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Publication
25633418 | J:246164
First Author: Khan MP
Year: 2015
Journal: Diabetes
Title: Pathophysiological Mechanism of Bone Loss in Type 2 Diabetes Involves Inverse Regulation of Osteoblast Function by PGC-1α and Skeletal Muscle Atrogenes: AdipoR1 as a Potential Target for Reversing Diabetes-Induced Osteopenia.
Volume: 64
Issue: 7
Pages: 2609-23
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Publication
17932568 | J:127400
First Author: Sun J
Year: 2007
Journal: J Clin Invest
Title: Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice.
Volume: 117
Issue: 11
Pages: 3359-68
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Publication
19633655 | J:152187
First Author: Liu J
Year: 2009
Journal: Nat Med
Title: Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.
Volume: 15
Issue: 8
Pages: 940-5
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Publication
29739755 | J:280006
First Author: Laguna-Fernandez A
Year: 2018
Journal: Circulation
Title: ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages.
Volume: 138
Issue: 16
Pages: 1693-1705
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Publication
21821913 | J:178258
First Author: Wang J
Year: 2011
Journal: J Clin Invest
Title: IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice.
Volume: 121
Issue: 9
Pages: 3564-77
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Publication
27183216 | J:239720
First Author: Cherepanova OA
Year: 2016
Journal: Nat Med
Title: Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective.
Volume: 22
Issue: 6
Pages: 657-65
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Publication
29880490 | J:284967
First Author: Centa M
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Acute Loss of Apolipoprotein E Triggers an Autoimmune Response That Accelerates Atherosclerosis.
Volume: 38
Issue: 8
Pages: e145-e158
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Publication
32674599 | J:318676
First Author: Alencar GF
Year: 2020
Journal: Circulation
Title: Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
Volume: 142
Issue: 21
Pages: 2045-2059
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Publication
24488984 | J:221696
First Author: Hilgendorf I
Year: 2014
Journal: Circulation
Title: Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity.
Volume: 129
Issue: 16
Pages: 1677-87
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Publication
16462800 | J:105800
First Author: Ait-Oufella H
Year: 2006
Journal: Nat Med
Title: Natural regulatory T cells control the development of atherosclerosis in mice.
Volume: 12
Issue: 2
Pages: 178-80
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Publication
25223984 | J:234151
First Author: Sage AP
Year: 2014
Journal: Circulation
Title: MHC Class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity.
Volume: 130
Issue: 16
Pages: 1363-73
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Publication
26950239 | J:258638
First Author: Xin A
Year: 2016
Journal: Nat Immunol
Title: A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet.
Volume: 17
Issue: 4
Pages: 422-32
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Publication
25092171 | J:218470
First Author: Wang J
Year: 2014
Journal: Biochim Biophys Acta
Title: Cathepsin G activity lowers plasma LDL and reduces atherosclerosis.
Volume: 1842
Issue: 11
Pages: 2174-83
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Publication
15197138 | J:102201
First Author: Pan JH
Year: 2004
Journal: Circulation
Title: Macrophage migration inhibitory factor deficiency impairs atherosclerosis in low-density lipoprotein receptor-deficient mice.
Volume: 109
Issue: 25
Pages: 3149-53
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Publication
23426179 | J:196393
First Author: Klingenberg R
Year: 2013
Journal: J Clin Invest
Title: Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis.
Volume: 123
Issue: 3
Pages: 1323-34
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Publication
21959219 | J:196562
First Author: Levin MC
Year: 2011
Journal: Circ Res
Title: Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation.
Volume: 109
Issue: 11
Pages: 1210-8
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Publication
20697023 | J:178588
First Author: Sun J
Year: 2010
Journal: Circulation
Title: Deficiency of antigen-presenting cell invariant chain reduces atherosclerosis in mice.
Volume: 122
Issue: 8
Pages: 808-20
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Publication
32004476 | J:286269
First Author: Yurdagul A Jr
Year: 2020
Journal: Cell Metab
Title: Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury.
Volume: 31
Issue: 3
Pages: 518-533.e10
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Publication
31130511 | J:280247
First Author: Lee S
Year: 2019
Journal: Cell Host Microbe
Title: A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis.
Volume: 25
Issue: 6
Pages: 845-857.e5
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Publication
30523786 | J:272601
First Author: Fu NY
Year: 2018
Journal: Dev Cell
Title: Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence.
Volume: 47
Issue: 5
Pages: 629-644.e8
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Publication
30930118 | J:274188
First Author: Rios AC
Year: 2019
Journal: Cancer Cell
Title: Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging.
Volume: 35
Issue: 4
Pages: 618-632.e6
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Publication
28775312 | J:253596
First Author: Alsøe L
Year: 2017
Journal: Sci Rep
Title: Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.
Volume: 7
Issue: 1
Pages: 7199
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Publication
31235962 | J:298791
First Author: Abdel-Gadir A
Year: 2019
Journal: Nat Med
Title: Microbiota therapy acts via a regulatory T cell MyD88/RORγt pathway to suppress food allergy.
Volume: 25
Issue: 7
Pages: 1164-1174
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Publication
11526474 | J:103960
First Author: Akbarian S
Year: 2001
Journal: Mol Psychiatry
Title: Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawal.
Volume: 6
Issue: 5
Pages: 593-604
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Publication
19770271 | J:152376
First Author: Tachdjian R
Year: 2009
Journal: J Exp Med
Title: Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma.
Volume: 206
Issue: 10
Pages: 2191-204
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Publication
17179084 | J:119997
First Author: Rubio-Aliaga I
Year: 2007
Journal: Genetics
Title: A genetic screen for modifiers of the delta1-dependent notch signaling function in the mouse.
Volume: 175
Issue: 3
Pages: 1451-63
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Publication
26690703 | J:231182
First Author: Eiymo Mwa Mpollo MS
Year: 2016
Journal: J Clin Invest
Title: Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13.
Volume: 126
Issue: 2
Pages: 571-84
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Publication
25730472 | J:274440
First Author: Fu NY
Year: 2015
Journal: Nat Cell Biol
Title: EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival.
Volume: 17
Issue: 4
Pages: 365-75
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Publication
32796837 | J:303340
First Author: Stevens ML
Year: 2020
Journal: Nat Commun
Title: Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk.
Volume: 11
Issue: 1
Pages: 4092
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Publication
32271879 | J:289392
 
First Author: Badhai J
Year: 2020
Journal: J Exp Med
Title: Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice.
Volume: 217
Issue: 6
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Publication
22329990 | J:182513
First Author: Wills-Karp M
Year: 2012
Journal: J Exp Med
Title: Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection.
Volume: 209
Issue: 3
Pages: 607-22
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Publication
34533976 | J:350747
First Author: Zhan Y
Year: 2021
Journal: Sci Immunol
Title: Differential requirement for the Polycomb repressor complex 2 in dendritic cell and tissue-resident myeloid cell homeostasis.
Volume: 6
Issue: 63
Pages: eabf7268
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Publication
30712876 | J:359967
First Author: Jin C
Year: 2019
Journal: Cell
Title: Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.
Volume: 176
Issue: 5
Pages: 998-1013.e16
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Publication
33984270 | J:308557
First Author: Ravi A
Year: 2021
Journal: Dev Cell
Title: PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay.
Volume: 56
Issue: 11
Pages: 1661-1676.e10
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Publication
31395607 | J:280046
First Author: Tandon M
Year: 2019
Journal: Cancer Res
Title: Prolactin Promotes Fibrosis and Pancreatic Cancer Progression.
Volume: 79
Issue: 20
Pages: 5316-5327
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Publication
28678006 | J:253558
   
First Author: Redhu NS
Year: 2017
Journal: Elife
Title: Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor.
Volume: 6
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Publication
26701909 | J:269070
   
First Author: Etemadi N
Year: 2015
Journal: Elife
Title: TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1.
Volume: 4
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Publication
18577706 | J:138893
First Author: Cohen PA
Year: 2008
Journal: Blood
Title: STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells.
Volume: 112
Issue: 5
Pages: 1832-43
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Publication
22796522 | J:193668
First Author: Sodhi CP
Year: 2012
Journal: Gastroenterology
Title: Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice.
Volume: 143
Issue: 3
Pages: 708-718.e5
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Publication
23319735 | J:193318
First Author: Commandeur S
Year: 2013
Journal: J Immunol
Title: An unbiased genome-wide Mycobacterium tuberculosis gene expression approach to discover antigens targeted by human T cells expressed during pulmonary infection.
Volume: 190
Issue: 4
Pages: 1659-71
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Publication
21768356 | J:176025
First Author: Croker BA
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1.
Volume: 108
Issue: 32
Pages: 13135-40
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Publication
39405291 | J:357552
First Author: McRae HM
Year: 2024
Journal: PLoS Genet
Title: Loss of PHF6 causes spontaneous seizures, enlarged brain ventricles and altered transcription in the cortex of a mouse model of the Börjeson-Forssman-Lehmann intellectual disability syndrome.
Volume: 20
Issue: 10
Pages: e1011428
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Publication
18475271 | J:149207
First Author: Lu A
Year: 2008
Journal: Mol Psychiatry
Title: Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior.
Volume: 13
Issue: 11
Pages: 1028-42
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Publication
26826102 | J:241103
First Author: Oaks AW
Year: 2017
Journal: Cereb Cortex
Title: Cc2d1a Loss of Function Disrupts Functional and Morphological Development in Forebrain Neurons Leading to Cognitive and Social Deficits.
Volume: 27
Issue: 2
Pages: 1670-1685
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Publication
36641753 | J:332921
First Author: Kueh AJ
Year: 2023
Journal: Cell Rep
Title: Stem cell plasticity, acetylation of H3K14, and de novo gene activation rely on KAT7.
Volume: 42
Issue: 1
Pages: 111980
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Publication
30307073 | J:296496
First Author: Yang JQ
Year: 2019
Journal: Clin Exp Allergy
Title: Rational targeting Cdc42 restrains Th2 cell differentiation and prevents allergic airway inflammation.
Volume: 49
Issue: 1
Pages: 92-107
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Publication
37450601 | J:338364
First Author: Schwarz MM
Year: 2023
Journal: Sci Adv
Title: Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice.
Volume: 9
Issue: 28
Pages: eadh2264
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Publication
28775125 | J:248308
First Author: Xiao X
Year: 2017
Journal: Diabetes
Title: SMAD3/Stat3 Signaling Mediates β-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis-Related Diabetes.
Volume: 66
Issue: 10
Pages: 2646-2658
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Publication
35545089 | J:324824
First Author: Park H
Year: 2022
Journal: Cell
Title: PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease.
Volume: 185
Issue: 11
Pages: 1943-1959.e21
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Publication
31366886 | J:279485
First Author: Vrahnas C
Year: 2019
Journal: Nat Commun
Title: Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone.
Volume: 10
Issue: 1
Pages: 3436
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Publication
20357110 | J:159387
First Author: Brigman JL
Year: 2010
Journal: J Neurosci
Title: Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning.
Volume: 30
Issue: 13
Pages: 4590-600
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Publication
28500878 | J:249734
 
First Author: Fontaine SN
Year: 2017
Journal: Neurobiol Aging
Title: Identification of changes in neuronal function as a consequence of aging and tauopathic neurodegeneration using a novel and sensitive magnetic resonance imaging approach.
Volume: 56
Pages: 78-86
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Publication
33108272 | J:319908
   
First Author: Millman DJ
Year: 2020
Journal: Elife
Title: VIP interneurons in mouse primary visual cortex selectively enhance responses to weak but specific stimuli.
Volume: 9
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Publication
18849970 | J:143599
First Author: Bredemeyer AL
Year: 2008
Journal: Nature
Title: DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes.
Volume: 456
Issue: 7223
Pages: 819-23
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Publication
21613355 | J:328798
First Author: Pojoga LH
Year: 2011
Journal: J Clin Endocrinol Metab
Title: Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension.
Volume: 96
Issue: 8
Pages: E1288-92
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Publication
25319415 | J:216674
First Author: Holmes ML
Year: 2014
Journal: EMBO J
Title: Peripheral natural killer cell maturation depends on the transcription factor Aiolos.
Volume: 33
Issue: 22
Pages: 2721-34
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Publication
21930782 | J:178780
First Author: Asselin-Labat ML
Year: 2011
Journal: Mol Cell Biol
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