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Search results 1501 to 1600 out of 2191 for MBP

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Type Details Score
Publication  
First Author: Schemmert S
Year: 2019
Journal: Neurobiol Dis
Title: Deceleration of the neurodegenerative phenotype in pyroglutamate-Aβ accumulating transgenic mice by oral treatment with the Aβ oligomer eliminating compound RD2.
Volume: 124
Pages: 36-45
Publication
First Author: Wirth S
Year: 2024
Journal: Glia
Title: Astrocytic uptake of posttranslationally modified amyloid-β leads to endolysosomal system disruption and induction of pro-inflammatory signaling.
Volume: 72
Issue: 8
Pages: 1451-1468
Publication
First Author: Smith KM
Year: 2012
Journal: J Immunol
Title: miR-29ab1 deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis.
Volume: 189
Issue: 4
Pages: 1567-76
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Hoffmann A
Year: 2019
Journal: Brain Pathol
Title: Oligodendroglial α-synucleinopathy-driven neuroinflammation in multiple system atrophy.
Volume: 29
Issue: 3
Pages: 380-396
Publication
First Author: Schneider Y
Year: 2024
Journal: Acta Neuropathol Commun
Title: Distinct forebrain regions define a dichotomous astrocytic profile in multiple system atrophy.
Volume: 12
Issue: 1
Pages: 1
Publication
First Author: Ettle B
Year: 2016
Journal: Acta Neuropathol
Title: α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy.
Volume: 132
Issue: 1
Pages: 59-75
Publication  
First Author: Lambrecht V
Year: 2020
Journal: Exp Neurol
Title: Quantitative susceptibility mapping depicts severe myelin deficit and iron deposition in a transgenic model of multiple system atrophy.
Volume: 329
Pages: 113314
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Valera E
Year: 2014
Journal: Glia
Title: Antidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of multiple system atrophy.
Volume: 62
Issue: 2
Pages: 317-37
Publication
First Author: Kleene R
Year: 2021
Journal: J Neurochem
Title: Revisiting the proteolytic processing of cell adhesion molecule L1.
Volume: 157
Issue: 4
Pages: 1102-1117
Strain
Attribute String: mutant strain, endonuclease-mediated mutation
Strain
Attribute String: endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Tg(CAG-p35)1Miur/? Tg(Mbp-cre)29Miur/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-EGFP-CAT-DTA)2Masa/? Tg(Mbp-cre,CAG-EGFP)53Masa/?
Background: involves: C3H * C3H/HeN * C57BL/6 * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-EGFP-CAT-lacZ)144-5Masa/? Tg(Mbp-cre,CAG-EGFP)53Masa/?
Background: involves: C3H * C3H/HeN * C57BL/6 * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Tg(TPO-cre)1Shk/?
Background: 129S1.Cg-Pten Tg(TPO-cre)1Shk
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn1b/Cdkn1b Pten/Pten Tg(TPO-cre)1Shk/?
Background: 129S1.Cg-Cdkn1b Tg(TPO-cre)1Shk Pten
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn1b/Cdkn1b<+> Pten/Pten Tg(TPO-cre)1Shk/?
Background: 129S1.Cg-Cdkn1b Tg(TPO-cre)1Shk Pten
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe/? Tg(TPO-cre)1Shk/?
Background: involves: FVB/NCr * FVB/NJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Trib2/Trib2
Background: involves: C57BL/6 * DBA/1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Igh/Igh Igk/Igk
Background: involves: 129S6/SvEvTac * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Igh/Igh Igk/Igk
Background: involves: 129S6/SvEvTac * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Igh/Igh
Background: involves: 129S6/SvEvTac * C57BL/6N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Mbp-SNCA)29Ema/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Mbp-SNCA)1Ema/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Pmp2/Pmp2
Background: involves: C57BL/6 * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Trp53/Trp53 Tg(TPO-cre)1Shk/?
Background: 129.Cg-Tg(TPO-cre)1Shk Trp53 Pten
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kras/Kras<+> Tg(TPO-cre)1Shk/?
Background: 129.Cg-Kras Tg(Tpo-cre)1Shk
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Prkar1a/Prkar1a Tg(TPO-cre)1Shk/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/NCr
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Tg(TPO-cre)1Shk/?
Background: involves: 129 * FVB/NCr
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-EGFP-CAT-lacZ)144-5Masa/? Tg(Mbp-cre,CAG-EGFP)53Masa/?
Background: involves: C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kras/Kras Tg(TPO-cre)1Shk/?
Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6N * FVB/NCr
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tbx3/Tbx3 Tg(TPO-cre)1Shk/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Sharff AJ
Year: 1993
Journal: Biochemistry
Title: Refined 1.8-A structure reveals the mode of binding of beta-cyclodextrin to the maltodextrin binding protein.
Volume: 32
Issue: 40
Pages: 10553-9
Publication
First Author: Sharff AJ
Year: 1992
Journal: Biochemistry
Title: Crystallographic evidence of a large ligand-induced hinge-twist motion between the two domains of the maltodextrin binding protein involved in active transport and chemotaxis.
Volume: 31
Issue: 44
Pages: 10657-63
Publication
First Author: Kamionka A
Year: 2001
Journal: FEMS Microbiol Lett
Title: Bacillus subtilis contains a cyclodextrin-binding protein which is part of a putative ABC-transporter.
Volume: 204
Issue: 1
Pages: 55-60
Protein Domain
Type: Family
Description: Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. Most of the bacterial ABC (ATP-binding cassette) importers are composed of one or two transmembrane permease proteins, one or two nucleotide-binding proteins and a highly specific periplasmic solute-binding protein. In Gram-negative bacteria the solute-binding proteins are dissolved in the periplasm, while in archaea and Gram-positive bacteria, their solute-binding proteins are membrane-anchored lipoproteins [, ].This entry includes maltodextrin binding proteins and cyclodextrin-binding proteins (also known as galactooligosaccharide-binding proteins) from bacteria and archaea.Maltodextrin binding protein (MBP) is the primary component of bacterial high-affinity active transport and chemotaxis []. It is a monomeric protein, with 2 globular domains separated by a 2- or 3-stranded hinge. MBP binds and transports linear oligosaccharides (of up to 7 glucosyl units), as well as 2 cyclic maltodextrins which, although binding tightly, cannot be transported nor initiate a chemotactic response []. It is thought that the hinge region is critical for the correct functioning of MBP, not just in the binding and recognition of sugars,but also in allowing and maintaining the integrity of initiation of both active transport and chemotaxis [].The cyclodextrin-binding protein CYCB (also known as galactooligosaccharide-binding protein GANS) from Bacillus subtilis has been characterised. It is part of the ABC transporter complex GanPQS involved in the uptake of galactooligosaccharides and it has a role in galactan degradation [, ].
Publication
First Author: Inoue T
Year: 1990
Journal: J Biol Chem
Title: Isolation of complementary DNAs encoding a cerebellum-enriched nuclear factor I family that activates transcription from the mouse myelin basic protein promoter.
Volume: 265
Issue: 31
Pages: 19065-70
Publication
First Author: Steplewski A
Year: 1995
Journal: Gene
Title: Regulation of mouse myelin basic protein gene transcription by a sequence-specific single-stranded DNA-binding protein in vitro.
Volume: 154
Issue: 2
Pages: 215-8
Publication
First Author: Graf D
Year: 2001
Journal: Mamm Genome
Title: Evolutionary conservation, developmental expression, and genomic mapping of mammalian Twisted gastrulation.
Volume: 12
Issue: 7
Pages: 554-60
Publication
First Author: Dautigny A
Year: 1986
Journal: Nature
Title: The structural gene coding for myelin-associated proteolipid protein is mutated in jimpy mice.
Volume: 321
Issue: 6073
Pages: 867-9
Publication
First Author: Oliveira-dos-Santos AJ
Year: 1999
Journal: J Immunol
Title: CD28 costimulation is crucial for the development of spontaneous autoimmune encephalomyelitis.
Volume: 162
Issue: 8
Pages: 4490-5
Publication  
First Author: Hosokawa M
Year: 2019
Journal: iScience
Title: Loss of RNA-Binding Protein Sfpq Causes Long-Gene Transcriptopathy in Skeletal Muscle and Severe Muscle Mass Reduction with Metabolic Myopathy.
Volume: 13
Pages: 229-242
Publication
First Author: Hedtjärn M
Year: 2005
Journal: Neurosci Lett
Title: White matter injury in the immature brain: role of interleukin-18.
Volume: 373
Issue: 1
Pages: 16-20
Publication
First Author: Cao Y
Year: 2012
Journal: J Genet
Title: Genomic dissection and prioritizing of candidate genes of QTL for regulating spontaneous arthritis on chromosome 1 in mice deficient for interleukin-1 receptor antagonist.
Volume: 91
Issue: 2
Pages: 119-28
Publication
First Author: Goverman J
Year: 1993
Journal: Cell
Title: Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity.
Volume: 72
Issue: 4
Pages: 551-60
Publication
First Author: Shimizu T
Year: 2013
Journal: Biochem Genet
Title: Genetic mapping of agenesis of the third molars in mice.
Volume: 51
Issue: 9-10
Pages: 728-36
Publication  
First Author: Xie YY
Year: 2021
Journal: Front Cell Dev Biol
Title: Clemastine Ameliorates Myelin Deficits via Preventing Senescence of Oligodendrocytes Precursor Cells in Alzheimer's Disease Model Mouse.
Volume: 9
Pages: 733945
Publication
First Author: Meister M
Year: 2015
Journal: J Invest Dermatol
Title: Self-Antigen Presentation by Keratinocytes in the Inflamed Adult Skin Modulates T-Cell Auto-Reactivity.
Volume: 135
Issue: 8
Pages: 1996-2004
Publication  
First Author: Hu Z
Year: 2018
Journal: Front Neurosci
Title: Silencing miR-150 Ameliorates Experimental Autoimmune Encephalomyelitis.
Volume: 12
Pages: 465
Publication
First Author: Mastronardi FG
Year: 1996
Journal: J Neurosci Res
Title: Loss of myelin basic protein cationicity in DM20 transgenic mice is dosage dependent.
Volume: 44
Issue: 4
Pages: 301-7
Publication
First Author: Fischer M
Year: 2017
Journal: Mamm Genome
Title: Large deletion on the Y-chromosome long arm (Yq) of C57BL/6JBomTac inbred mice.
Volume: 28
Issue: 1-2
Pages: 31-37
Publication
First Author: Sakuraba Y
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Molecular characterization of ENU mouse mutagenesis and archives.
Volume: 336
Issue: 2
Pages: 609-16
Publication
First Author: Yang H
Year: 2016
Journal: Acta Biochim Biophys Sin (Shanghai)
Title: Mup-knockout mice generated through CRISPR/Cas9-mediated deletion for use in urinary protein analysis.
Volume: 48
Issue: 5
Pages: 468-73
Publication
First Author: Cox RD
Year: 1993
Journal: Mamm Genome
Title: Detailed physical and genetic mapping in the region of plasminogen, D17Rp17e, and quaking.
Volume: 4
Issue: 12
Pages: 687-94
Publication
First Author: Duong TT
Year: 1994
Journal: J Neuroimmunol
Title: Effect of anti-interferon-gamma monoclonal antibody treatment on the development of experimental allergic encephalomyelitis in resistant mouse strains.
Volume: 53
Issue: 1
Pages: 101-7
Publication
First Author: Sobel RA
Year: 1994
Journal: Neurochem Res
Title: Minireview: autoimmune responses to myelin proteolipid protein.
Volume: 19
Issue: 8
Pages: 915-21
Publication
First Author: Fritz RB
Year: 1995
Journal: J Neuroimmunol
Title: Thymic expression of the golli-myelin basic protein gene in the SJL/J mouse.
Volume: 57
Issue: 1-2
Pages: 93-9
Publication
First Author: Pitchekian-Halabi H
Year: 1996
Journal: J Neuroimmunol
Title: Strain-related differences in the ability of T lymphocytes to recognize proteins encoded by the golli-myelin basic protein gene.
Volume: 68
Issue: 1-2
Pages: 121-9
Publication
First Author: Fritz RB
Year: 1996
Journal: J Neurosci Res
Title: Active and passive experimental autoimmune encephalomyelitis in strain 129/J (H-2b) mice.
Volume: 45
Issue: 4
Pages: 471-4
Publication
First Author: Kim JY
Year: 2003
Journal: J Neurosci
Title: The role of ErbB2 signaling in the onset of terminal differentiation of oligodendrocytes in vivo.
Volume: 23
Issue: 13
Pages: 5561-71
Publication
First Author: Radja F
Year: 2003
Journal: J Virol
Title: Oligodendrocyte-specific expression of human immunodeficiency virus type 1 Nef in transgenic mice leads to vacuolar myelopathy and alters oligodendrocyte phenotype in vitro.
Volume: 77
Issue: 21
Pages: 11745-53
Publication
First Author: Wagner LA
Year: 2007
Journal: Blood
Title: EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression.
Volume: 109
Issue: 12
Pages: 5191-8
Publication
First Author: Hamabe-Horiike T
Year: 2021
Journal: Sci Rep
Title: Glial cell type-specific gene expression in the mouse cerebrum using the piggyBac system and in utero electroporation.
Volume: 11
Issue: 1
Pages: 4864
Protein
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: true
Publication
First Author: Watzlawick H
Year: 2016
Journal: J Bacteriol
Title: Role of the ganSPQAB Operon in Degradation of Galactan by Bacillus subtilis.
Volume: 198
Issue: 20
Pages: 2887-96
Publication
First Author: Casu C
Year: 2020
Journal: Haematologica
Title: Minihepcidins improve ineffective erythropoiesis and splenomegaly in a new mouse model of adult β-thalassemia major.
Volume: 105
Issue: 7
Pages: 1835-1844
Publication
First Author: Rork TH
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Adenosine A2A receptor activation reduces infarct size in the isolated, perfused mouse heart by inhibiting resident cardiac mast cell degranulation.
Volume: 295
Issue: 5
Pages: H1825-33
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: transgenic, mutant stock, spontaneous mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication    
First Author: Veltrop M
Year: 2013
Journal: PLoS Curr
Title: Generation of embryonic stem cells and mice for duchenne research.
Volume: 5
Publication
First Author: Lala-Tabbert N
Year: 2016
Journal: Stem Cells Transl Med
Title: Induction of CCAAT/Enhancer-Binding Protein β Expression With the Phosphodiesterase Inhibitor Isobutylmethylxanthine Improves Myoblast Engraftment Into Dystrophic Muscle.
Volume: 5
Issue: 4
Pages: 500-10
Publication
First Author: Madaro L
Year: 2019
Journal: PLoS Genet
Title: Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
Volume: 15
Issue: 10
Pages: e1008408
Publication
First Author: Hamid T
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: TNF receptor signaling inhibits cardiomyogenic differentiation of cardiac stem cells and promotes a neuroadrenergic-like fate.
Volume: 311
Issue: 5
Pages: H1189-H1201
Publication
First Author: Kurkjian C
Year: 2012
Journal: Infect Immun
Title: Alveolar macrophages in neonatal mice are inherently unresponsive to Pneumocystis murina infection.
Volume: 80
Issue: 8
Pages: 2835-46
Publication
First Author: Nishimura T
Year: 2021
Journal: Cell Stem Cell
Title: Generation of Functional Organs Using a Cell-Competitive Niche in Intra- and Inter-species Rodent Chimeras.
Volume: 28
Issue: 1
Pages: 141-149.e3
Publication
First Author: Zhu X
Year: 2014
Journal: J Immunol
Title: Scavenger receptor function of mouse Fcγ receptor III contributes to progression of atherosclerosis in apolipoprotein E hyperlipidemic mice.
Volume: 193
Issue: 5
Pages: 2483-95
Publication
First Author: Cortez-Retamozo V
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Origins of tumor-associated macrophages and neutrophils.
Volume: 109
Issue: 7
Pages: 2491-6
Publication
First Author: Cortez-Retamozo V
Year: 2013
Journal: Immunity
Title: Angiotensin II drives the production of tumor-promoting macrophages.
Volume: 38
Issue: 2
Pages: 296-308
Publication
First Author: Van Eck M
Year: 2007
Journal: Circ Res
Title: Important role for bone marrow-derived cholesteryl ester transfer protein in lipoprotein cholesterol redistribution and atherosclerotic lesion development in LDL receptor knockout mice.
Volume: 100
Issue: 5
Pages: 678-85
Publication
First Author: Cabinian A
Year: 2018
Journal: Gut
Title: Gut symbiotic microbes imprint intestinal immune cells with the innate receptor SLAMF4 which contributes to gut immune protection against enteric pathogens.
Volume: 67
Issue: 5
Pages: 847-859
Publication
First Author: Miller KA
Year: 2009
Journal: Cancer Res
Title: Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo.
Volume: 69
Issue: 8
Pages: 3689-94
Publication
First Author: Kusakabe T
Year: 2006
Journal: Mol Endocrinol
Title: Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid.
Volume: 20
Issue: 8
Pages: 1796-809
Publication
First Author: Chaney KE
Year: 2020
Journal: Cancer Res
Title: Cdkn2a Loss in a Model of Neurofibroma Demonstrates Stepwise Tumor Progression to Atypical Neurofibroma and MPNST.
Volume: 80
Issue: 21
Pages: 4720-4730
Publication
First Author: Huang X
Year: 2010
Journal: Blood Cells Mol Dis
Title: Erythropoietin receptor signaling regulates both erythropoiesis and megakaryopoiesis in vivo.
Volume: 44
Issue: 1
Pages: 1-6
Publication
First Author: Carmi Y
Year: 2013
Journal: J Immunol
Title: The role of IL-1β in the early tumor cell-induced angiogenic response.
Volume: 190
Issue: 7
Pages: 3500-9
Publication
First Author: Hisatomi T
Year: 2008
Journal: J Clin Invest
Title: HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice.
Volume: 118
Issue: 6
Pages: 2025-38
Publication  
First Author: Ren XS
Year: 2024
Journal: Int J Mol Sci
Title: Hematopoietic Growth Factors Regulate the Entry of Monocytes into the Adult Brain via Chemokine Receptor CCR5.
Volume: 25
Issue: 16
Publication
First Author: Tian D
Year: 2023
Journal: Theranostics
Title: TCRαβ(+)NK1.1(-)CD4(-)CD8(-) double-negative T cells inhibit central and peripheral inflammation and ameliorate ischemic stroke in mice.
Volume: 13
Issue: 3
Pages: 896-909
Publication
First Author: Kusakabe T
Year: 2004
Journal: Genesis
Title: Thyrocyte-specific expression of Cre recombinase in transgenic mice.
Volume: 39
Issue: 3
Pages: 212-6
Strain
Attribute String: mutant stock, targeted mutation, transgenic
Publication
First Author: Prinz M
Year: 2004
Journal: J Neurosci
Title: Intrinsic resistance of oligodendrocytes to prion infection.
Volume: 24
Issue: 26
Pages: 5974-81
Publication
First Author: Knauf JA
Year: 2018
Journal: J Clin Invest
Title: Hgf/Met activation mediates resistance to BRAF inhibition in murine anaplastic thyroid cancers.
Volume: 128
Issue: 9
Pages: 4086-4097
Publication
First Author: Li H
Year: 2011
Journal: PLoS One
Title: Activation of PPARγ in myeloid cells promotes lung cancer progression and metastasis.
Volume: 6
Issue: 12
Pages: e28133
Publication
First Author: Furuhashi M
Year: 2008
Journal: J Clin Invest
Title: Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice.
Volume: 118
Issue: 7
Pages: 2640-50
Publication
First Author: Shimamura M
Year: 2018
Journal: PLoS One
Title: Mouse models of sporadic thyroid cancer derived from BRAFV600E alone or in combination with PTEN haploinsufficiency under physiologic TSH levels.
Volume: 13
Issue: 8
Pages: e0201365