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Search results 1501 to 1600 out of 2672 for Mapt

0.017s
Type Details Score
Publication
First Author: Martinez P
Year: 2022
Journal: Nat Neurosci
Title: Bassoon contributes to tau-seed propagation and neurotoxicity.
Volume: 25
Issue: 12
Pages: 1597-1607
Publication  
First Author: Géraudie A
Year: 2023
Journal: Int J Mol Sci
Title: Effects of Low-Intensity Pulsed Ultrasound-Induced Blood-Brain Barrier Opening in P301S Mice Modeling Alzheimer's Disease Tauopathies.
Volume: 24
Issue: 15
Publication
First Author: Hou K
Year: 2024
Journal: Sci Adv
Title: D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer's disease.
Volume: 10
Issue: 18
Pages: eadl2991
Publication  
First Author: Collu R
Year: 2023
Journal: Biomed Pharmacother
Title: Angiotensin-converting enzyme inhibitors and statins therapies-induced changes in omics profiles in humans and transgenic tau mice.
Volume: 168
Pages: 115756
Publication
First Author: Yang T
Year: 2020
Journal: Acta Neuropathol Commun
Title: Small-molecule modulation of the p75 neurotrophin receptor inhibits a wide range of tau molecular pathologies and their sequelae in P301S tauopathy mice.
Volume: 8
Issue: 1
Pages: 156
Publication
First Author: Jiang L
Year: 2021
Journal: Mol Cell
Title: Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy.
Volume: 81
Issue: 20
Pages: 4209-4227.e12
Publication
First Author: Dumont M
Year: 2011
Journal: FASEB J
Title: Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice.
Volume: 25
Issue: 11
Pages: 4063-72
Publication
First Author: Jiang T
Year: 2015
Journal: Neurobiol Aging
Title: Silencing of TREM2 exacerbates tau pathology, neurodegenerative changes, and spatial learning deficits in P301S tau transgenic mice.
Volume: 36
Issue: 12
Pages: 3176-3186
Publication  
First Author: Burke K
Year: 2024
Journal: JASA Express Lett
Title: Auditory brainstem response audiometry in tauopathy mouse model of human Alzheimer's disease.
Volume: 4
Issue: 7
Publication
First Author: Tang SJ
Year: 2020
Journal: Acta Neuropathol Commun
Title: Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy.
Volume: 8
Issue: 1
Pages: 96
Publication
First Author: Rimal S
Year: 2023
Journal: EMBO Rep
Title: Reverse electron transfer is activated during aging and contributes to aging and age-related disease.
Volume: 24
Issue: 4
Pages: e55548
Publication    
First Author: Cecon E
Year: 2023
Journal: Elife
Title: Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells.
Volume: 12
Publication
First Author: Perea JR
Year: 2022
Journal: Sci Rep
Title: p38 activation occurs mainly in microglia in the P301S Tauopathy mouse model.
Volume: 12
Issue: 1
Pages: 2130
Publication
First Author: Parra Bravo C
Year: 2024
Journal: Mol Neurodegener
Title: Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.
Volume: 19
Issue: 1
Pages: 51
Publication
First Author: Cogut V
Year: 2024
Journal: J Alzheimers Dis
Title: Caloric Restriction Improves Spatial Learning Deficits in Tau Mice.
Volume: 98
Issue: 3
Pages: 925-940
Publication
First Author: El Fatimy R
Year: 2018
Journal: Acta Neuropathol
Title: MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways.
Volume: 136
Issue: 4
Pages: 537-555
Publication  
First Author: DeVos SL
Year: 2017
Journal: Sci Transl Med
Title: Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.
Volume: 9
Issue: 374
Publication
First Author: Prissette M
Year: 2022
Journal: Cell Rep
Title: Disruption of nuclear envelope integrity as a possible initiating event in tauopathies.
Volume: 40
Issue: 8
Pages: 111249
Publication
First Author: Hovakimyan A
Year: 2019
Journal: Sci Rep
Title: A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice.
Volume: 9
Issue: 1
Pages: 15455
Publication
First Author: Yoo CJ
Year: 2024
Journal: FEBS J
Title: Complement receptor 4 mediates the clearance of extracellular tau fibrils by microglia.
Volume: 291
Issue: 15
Pages: 3499-3520
Publication  
First Author: Schweig JE
Year: 2020
Journal: Neurosci Lett
Title: Neuronal Spleen tyrosine kinase (SYK) mediates cytokine release in Transgenic Tau P301S mice organotypic brain slice cultures.
Volume: 729
Pages: 134992
Publication
First Author: Wang P
Year: 2023
Journal: Cell Biosci
Title: PI3K-AKT activation resculpts integrin signaling to drive filamentous tau-induced proinflammatory astrogliosis.
Volume: 13
Issue: 1
Pages: 179
Publication
First Author: Williams JB
Year: 2023
Journal: Nat Commun
Title: Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model.
Volume: 14
Issue: 1
Pages: 91
Publication  
First Author: Zhong S
Year: 2023
Journal: Molecules
Title: Quercetagitrin Inhibits Tau Accumulation and Reverses Neuroinflammation and Cognitive Deficits in P301S-Tau Transgenic Mice.
Volume: 28
Issue: 9
Publication  
First Author: Yu H
Year: 2023
Journal: Front Aging Neurosci
Title: The Îł-Adducin 1-357 fragment promotes tau pathology.
Volume: 15
Pages: 1241750
Publication  
First Author: Yanamandra K
Year: 2017
Journal: Sci Transl Med
Title: Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy.
Volume: 9
Issue: 386
Publication
First Author: Onishi T
Year: 2021
Journal: Sci Rep
Title: A novel orally active HDAC6 inhibitor T-518 shows a therapeutic potential for Alzheimer's disease and tauopathy in mice.
Volume: 11
Issue: 1
Pages: 15423
Publication
First Author: Arouche-Delaperche L
Year: 2023
Journal: Acta Neuropathol Commun
Title: Dysfunction of the glutamatergic photoreceptor synapse in the P301S mouse model of tauopathy.
Volume: 11
Issue: 1
Pages: 5
Publication  
First Author: Cazzaro S
Year: 2022
Journal: Front Aging Neurosci
Title: Slingshot homolog-1 mediates the secretion of small extracellular vesicles containing misfolded proteins by regulating autophagy cargo receptors and actin dynamics.
Volume: 14
Pages: 933979
Publication  
First Author: Zupancic JM
Year: 2023
Journal: Front Immunol
Title: Quantitative flow cytometric selection of tau conformational nanobodies specific for pathological aggregates.
Volume: 14
Pages: 1164080
Publication  
First Author: Koga S
Year: 2014
Journal: Neurobiol Dis
Title: Effects of diet-induced obesity and voluntary exercise in a tauopathy mouse model: implications of persistent hyperleptinemia and enhanced astrocytic leptin receptor expression.
Volume: 71
Pages: 180-92
Publication
First Author: Zhang X
Year: 2024
Journal: PLoS Biol
Title: Bridging integrator 1 fragment accelerates tau aggregation and propagation by enhancing clathrin-mediated endocytosis in mice.
Volume: 22
Issue: 1
Pages: e3002470
Publication
First Author: Lang SC
Year: 2017
Journal: J Immunol
Title: Neurodegeneration Enhances the Development of Arthritis.
Volume: 198
Issue: 6
Pages: 2394-2402
Publication
First Author: Lecocq S
Year: 2018
Journal: PLoS One
Title: Aptamers as biomarkers for neurological disorders. Proof of concept in transgenic mice.
Volume: 13
Issue: 1
Pages: e0190212
Publication
First Author: Eteläinen TS
Year: 2023
Journal: Sci Transl Med
Title: A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy.
Volume: 15
Issue: 691
Pages: eabq2915
Publication
First Author: Pandey S
Year: 2022
Journal: Cell Rep
Title: Disease-associated oligodendrocyte responses across neurodegenerative diseases.
Volume: 40
Issue: 8
Pages: 111189
Publication
First Author: Ising C
Year: 2017
Journal: J Exp Med
Title: AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy.
Volume: 214
Issue: 5
Pages: 1227-1238
Publication
First Author: Liu M
Year: 2019
Journal: J Alzheimers Dis
Title: Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice.
Volume: 69
Issue: 4
Pages: 1077-1087
Publication  
First Author: Liu C
Year: 2024
Journal: JCI Insight
Title: PM2.5 triggers tau aggregation in a mouse model of tauopathy.
Volume: 9
Issue: 14
Publication
First Author: Wang Y
Year: 2017
Journal: Oncotarget
Title: COX-2 metabolic products, the prostaglandin I(2) and F(2α), mediate the effects of TNF-α and Zn(2+) in stimulating the phosphorylation of Tau.
Volume: 8
Issue: 59
Pages: 99296-99311
Publication
First Author: Barker SJ
Year: 2021
Journal: Sci Transl Med
Title: MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration.
Volume: 13
Issue: 618
Pages: eabd7695
Publication
First Author: Vemula P
Year: 2019
Journal: Amino Acids
Title: Altered brain arginine metabolism in a mouse model of tauopathy.
Volume: 51
Issue: 3
Pages: 513-528
Publication
First Author: Li Y
Year: 2017
Journal: J Alzheimers Dis
Title: Tau Pathology Promotes the Reorganization of the Extracellular Matrix and Inhibits the Formation of Perineuronal Nets by Regulating the Expression and the Distribution of Hyaluronic Acid Synthases.
Volume: 57
Issue: 2
Pages: 395-409
Publication
First Author: Dejanovic B
Year: 2018
Journal: Neuron
Title: Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.
Volume: 100
Issue: 6
Pages: 1322-1336.e7
Publication  
First Author: Sandusky-Beltran LA
Year: 2021
Journal: J Clin Invest
Title: Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology.
Volume: 131
Issue: 4
Publication  
First Author: Drieu A
Year: 2023
Journal: Life Sci Alliance
Title: Parenchymal border macrophages regulate tau pathology and tau-mediated neurodegeneration.
Volume: 6
Issue: 11
Publication
First Author: Paris D
Year: 2014
Journal: J Biol Chem
Title: The spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation.
Volume: 289
Issue: 49
Pages: 33927-44
Publication
First Author: Wang P
Year: 2017
Journal: Acta Neuropathol
Title: Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.
Volume: 133
Issue: 5
Pages: 731-749
Publication
First Author: Zhang X
Year: 2023
Journal: Nat Commun
Title: Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer's disease.
Volume: 14
Issue: 1
Pages: 6670
Publication
First Author: Zheng N
Year: 2025
Journal: Transl Psychiatry
Title: Electrophysiology-based screening identifies neuronal HtrA serine peptidase 2 (HTRA2) as a synaptic plasticity regulator participating in tauopathy.
Volume: 15
Issue: 1
Pages: 5
Publication
First Author: Ye J
Year: 2025
Journal: Mol Neurodegener
Title: Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis.
Volume: 20
Issue: 1
Pages: 5
Publication  
First Author: Perez-Garcia G
Year: 2023
Journal: Neurosci Lett
Title: BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPT(P301S) mouse model of tauopathy.
Volume: 797
Pages: 137080
Publication  
First Author: Vallés-Saiz L
Year: 2023
Journal: Int J Mol Sci
Title: Lamivudine (3TC), a Nucleoside Reverse Transcriptase Inhibitor, Prevents the Neuropathological Alterations Present in Mutant Tau Transgenic Mice.
Volume: 24
Issue: 13
Publication
First Author: Cascella R
Year: 2023
Journal: Ann Med
Title: An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature.
Volume: 55
Issue: 1
Pages: 72-88
Publication
First Author: Zhao S
Year: 2023
Journal: Neurotherapeutics
Title: Metformin Attenuates Tau Pathology in Tau-Seeded PS19 Mice.
Volume: 20
Issue: 2
Pages: 452-463
Publication
First Author: Sun Y
Year: 2020
Journal: J Neuroinflammation
Title: The behavioural and neuropathologic sexual dimorphism and absence of MIP-3α in tau P301S mouse model of Alzheimer's disease.
Volume: 17
Issue: 1
Pages: 72
Publication
First Author: Dumont M
Year: 2012
Journal: Hum Mol Genet
Title: Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice.
Volume: 21
Issue: 23
Pages: 5091-105
Publication
First Author: Sanders DW
Year: 2014
Journal: Neuron
Title: Distinct tau prion strains propagate in cells and mice and define different tauopathies.
Volume: 82
Issue: 6
Pages: 1271-88
Publication
First Author: Chalermpalanupap T
Year: 2018
Journal: J Neurosci
Title: Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.
Volume: 38
Issue: 1
Pages: 74-92
Publication
First Author: Giannopoulos PF
Year: 2018
Journal: Aging Cell
Title: Antileukotriene therapy by reducing tau phosphorylation improves synaptic integrity and cognition of P301S transgenic mice.
Volume: 17
Issue: 3
Pages: e12759
Publication
First Author: Stack C
Year: 2014
Journal: Hum Mol Genet
Title: Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity.
Volume: 23
Issue: 14
Pages: 3716-32
Publication
First Author: Xu D
Year: 2020
Journal: Nature
Title: Modulating TRADD to restore cellular homeostasis and inhibit apoptosis.
Volume: 587
Issue: 7832
Pages: 133-138
Publication
First Author: Li LJ
Year: 2024
Journal: Transl Neurodegener
Title: Neuronal double-stranded DNA accumulation induced by DNase II deficiency drives tau phosphorylation and neurodegeneration.
Volume: 13
Issue: 1
Pages: 39
Publication
First Author: Zhao X
Year: 2023
Journal: Sci Transl Med
Title: A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury.
Volume: 15
Issue: 713
Pages: eabo6889
Publication  
First Author: Soler H
Year: 2017
Journal: Neurobiol Aging
Title: The GABAergic septohippocampal connection is impaired in a mouse model of tauopathy.
Volume: 49
Pages: 40-51
Publication  
First Author: Llorens-Martin M
Year: 2011
Journal: Neuroscience
Title: Expression of frontotemporal dementia with parkinsonism associated to chromosome 17 tau induces specific degeneration of the ventral dentate gyrus and depressive-like behavior in mice.
Volume: 196
Pages: 215-27
Publication  
First Author: GarcĂ­a-Cabrero AM
Year: 2013
Journal: Neurobiol Dis
Title: Hyperexcitability and epileptic seizures in a model of frontotemporal dementia.
Volume: 58
Pages: 200-8
Publication
First Author: Terreros-Roncal J
Year: 2019
Journal: J Neurosci
Title: Activity-Dependent Reconnection of Adult-Born Dentate Granule Cells in a Mouse Model of Frontotemporal Dementia.
Volume: 39
Issue: 29
Pages: 5794-5815
Publication
First Author: Silveyra MX
Year: 2012
Journal: Neurobiol Aging
Title: Altered expression of brain acetylcholinesterase in FTDP-17 human tau transgenic mice.
Volume: 33
Issue: 3
Pages: 624.e23-34
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Rosenmann H
Year: 2008
Journal: Exp Neurol
Title: A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics.
Volume: 212
Issue: 1
Pages: 71-84
Allele
Name: transgene insertion 1, Gerard Schellenberg
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion, Ruben Vidal
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion, Eva-Maria Mandelkow
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Strain
Attribute String: transgenic, mutant strain, congenic
Strain
Attribute String: transgenic, mutant strain, congenic
Allele
Name: transgene insertion 1, Li Gan
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 286, Li Gan
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: cholinergic receptor, nicotinic, alpha polypeptide 7; targeted mutation 3.1, Scott W Rogers
Allele Type: Targeted
Attribute String: Reporter
Allele
Name: transgene insertion L1, Lennart Mucke
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: microtubule-associated protein tau; targeted mutation 1, Martyn Goulding
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
Strain
Attribute String: mutant strain, congenic, transgenic
Allele
Name: transgene insertion 530, Tong Li
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
Allele
Name: transchromosomal, human 17, line 1, Michael Koob; transchromosomal, human 17, line 1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Allele
Name: transchromosomal, human 17, line 1, Michael Koob; transchromosomal, human 17, line 1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transchromosomal, human 17, line 2, Michael Koob; transchromosomal, human 17, line 2, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: other, mutant strain, congenic
Allele
Name: transchromosomal, human 17, line 2, Michael Koob; transchromosomal, human 17, line 1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 220, Junji Hirota
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Allele
Name: transgene insertion U79, Junji Hirota
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Allele
Name: transgene insertion U29, Junji Hirota
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Allele
Name: transgene insertion U16, Junji Hirota
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Allele
Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 3, Harwell
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Inserted expressed sequence
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Mapt/Mapt
Background: involves: 129/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Mapt/Mapt<+>
Background: involves: 129/Sv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-MAPT)43Vle/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true