| Type |
Details |
Score |
| Genotype |
| Symbol: |
Hand1/Hand1<+> Tg(Mef2c-cre)2Blk/? |
| Background: |
Not Specified |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mef2c-cre)2Blk/? |
| Background: |
involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mef2c-cre)2Blk/? |
| Background: |
involves: 129S4/SvJaeSor |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Myog-cre)1Eno/? |
| Background: |
involves: 129S4/SvJaeSor |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
167
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
159
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
155
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
170
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
182
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
177
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
110
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Y |
| Year: |
2021 |
| Journal: |
FASEB J |
| Title: |
Cystathionine gamma-lyase/H2 S signaling facilitates myogenesis under aging and injury condition. |
| Volume: |
35 |
| Issue: |
5 |
| Pages: |
e21511 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Quattrocelli M |
| Year: |
2019 |
| Journal: |
JCI Insight |
| Title: |
Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming. |
| Volume: |
4 |
| Issue: |
24 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Biressi S |
| Year: |
2008 |
| Journal: |
Cell Death Differ |
| Title: |
The homeobox gene Arx is a novel positive regulator of embryonic myogenesis. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
94-104 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Loers G |
| Year: |
2022 |
| Journal: |
Int J Mol Sci |
| Title: |
The Cell Adhesion Molecule L1 Interacts with Methyl CpG Binding Protein 2 via Its Intracellular Domain. |
| Volume: |
23 |
| Issue: |
7 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takahashi A |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Autocrine regulation of mesenchymal progenitor cell fates orchestrates tooth eruption. |
| Volume: |
116 |
| Issue: |
2 |
| Pages: |
575-580 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
van Oort RJ |
| Year: |
2006 |
| Journal: |
Circulation |
| Title: |
MEF2 activates a genetic program promoting chamber dilation and contractile dysfunction in calcineurin-induced heart failure. |
| Volume: |
114 |
| Issue: |
4 |
| Pages: |
298-308 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lim CK |
| Year: |
2021 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Dimethyl sulfoxide (DMSO) enhances direct cardiac reprogramming by inhibiting the bromodomain of coactivators CBP/p300. |
| Volume: |
160 |
|
| Pages: |
15-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pattison MJ |
| Year: |
2020 |
| Journal: |
Biosci Rep |
| Title: |
Loss of Mef2D function enhances TLR induced IL-10 production in macrophages. |
| Volume: |
40 |
| Issue: |
8 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Medrano JL |
| Year: |
2017 |
| Journal: |
J Biol Chem |
| Title: |
The transcription factor MEF2A fine-tunes gene expression in the atrial and ventricular chambers of the adult heart. |
| Volume: |
292 |
| Issue: |
51 |
| Pages: |
20975-20988 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nam YJ |
| Year: |
2014 |
| Journal: |
Development |
| Title: |
Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors. |
| Volume: |
141 |
| Issue: |
22 |
| Pages: |
4267-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cannon MV |
| Year: |
2015 |
| Journal: |
EMBO Mol Med |
| Title: |
Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization. |
| Volume: |
7 |
| Issue: |
9 |
| Pages: |
1229-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Amat R |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD. |
| Volume: |
284 |
| Issue: |
33 |
| Pages: |
21872-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Paul P |
| Year: |
2019 |
| Journal: |
PLoS One |
| Title: |
Dopamine receptor antagonists as potential therapeutic agents for ADPKD. |
| Volume: |
14 |
| Issue: |
5 |
| Pages: |
e0216220 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bonnet N |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Regulation of beta catenin signaling and parathyroid hormone anabolic effects in bone by the matricellular protein periostin. |
| Volume: |
109 |
| Issue: |
37 |
| Pages: |
15048-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kikuchi M |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice. |
| Volume: |
11 |
| Issue: |
7 |
| Pages: |
e0159375 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Barker SJ |
| Year: |
2021 |
| Journal: |
Sci Transl Med |
| Title: |
MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration. |
| Volume: |
13 |
| Issue: |
618 |
| Pages: |
eabd7695 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baertschi S |
| Year: |
2007 |
| Journal: |
FEBS J |
| Title: |
Mice with a targeted disruption of the Fgfrl1 gene die at birth due to alterations in the diaphragm. |
| Volume: |
274 |
| Issue: |
23 |
| Pages: |
6241-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GarcÃa-Padilla C |
| Year: |
2019 |
| Journal: |
Biochim Biophys Acta Gene Regul Mech |
| Title: |
Differential chamber-specific expression and regulation of long non-coding RNAs during cardiac development. |
| Volume: |
1862 |
| Issue: |
10 |
| Pages: |
194435 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aoto K |
| Year: |
2015 |
| Journal: |
Dev Biol |
| Title: |
Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells. |
| Volume: |
402 |
| Issue: |
1 |
| Pages: |
3-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shi L |
| Year: |
2024 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Downregulation of Wtap causes dilated cardiomyopathy and heart failure. |
| Volume: |
188 |
|
| Pages: |
38-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skerjanc IS |
| Year: |
1998 |
| Journal: |
J Biol Chem |
| Title: |
Myocyte enhancer factor 2C and Nkx2-5 up-regulate each other's expression and initiate cardiomyogenesis in P19 cells. |
| Volume: |
273 |
| Issue: |
52 |
| Pages: |
34904-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Iezzi S |
| Year: |
2002 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. |
| Volume: |
99 |
| Issue: |
11 |
| Pages: |
7757-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Du Y |
| Year: |
2005 |
| Journal: |
Blood |
| Title: |
Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis. |
| Volume: |
106 |
| Issue: |
7 |
| Pages: |
2498-505 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thai MV |
| Year: |
1998 |
| Journal: |
J Biol Chem |
| Title: |
Myocyte enhancer factor 2 (MEF2)-binding site is required for GLUT4 gene expression in transgenic mice. Regulation of MEF2 DNA binding activity in insulin-deficient diabetes. |
| Volume: |
273 |
| Issue: |
23 |
| Pages: |
14285-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Roque-RamÃrez B |
| Year: |
2014 |
| Journal: |
Dev Dyn |
| Title: |
Expression pattern of mRNA A and mRNA B of alpha sarcoglycan gene during mouse embryonic development and regulation of their expression by myogenic and cardiogenic transcription factors. |
| Volume: |
243 |
| Issue: |
11 |
| Pages: |
1416-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vitali C |
| Year: |
2015 |
| Journal: |
Cancer Res |
| Title: |
SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias. |
| Volume: |
75 |
| Issue: |
11 |
| Pages: |
2387-99 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu M |
| Year: |
2016 |
| Journal: |
Gene |
| Title: |
MicroRNA-29c overexpression inhibits proliferation and promotes apoptosis and differentiation in P19 embryonal carcinoma cells. |
| Volume: |
576 |
| Issue: |
1 Pt 2 |
| Pages: |
304-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jeong MH |
| Year: |
2016 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
A Shh coreceptor Cdo is required for efficient cardiomyogenesis of pluripotent stem cells. |
| Volume: |
93 |
|
| Pages: |
57-66 |
|
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•
•
•
•
|
| Publication |
| First Author: |
Ackert-Bicknell CL |
| Year: |
2010 |
| Journal: |
J Bone Miner Res |
| Title: |
Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map. |
| Volume: |
25 |
| Issue: |
8 |
| Pages: |
1808-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun N |
| Year: |
2019 |
| Journal: |
J Biol Chem |
| Title: |
Effects of histone deacetylase inhibitor Scriptaid and parathyroid hormone on osteocyte functions and metabolism. |
| Volume: |
294 |
| Issue: |
25 |
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9722-9733 |
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•
•
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| First Author: |
Hirai H |
| Year: |
2018 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
Direct Reprogramming of Fibroblasts Into Smooth Muscle-Like Cells With Defined Transcription Factors-Brief Report. |
| Volume: |
38 |
| Issue: |
9 |
| Pages: |
2191-2197 |
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•
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| First Author: |
Shen Y |
| Year: |
2023 |
| Journal: |
Stem Cells |
| Title: |
Uncovering the Heterogeneity of Cardiac Lin-KIT+ Cells: A scRNA-seq Study on the Identification of Subpopulations. |
| Volume: |
41 |
| Issue: |
10 |
| Pages: |
958-970 |
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•
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| First Author: |
Olson DP |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake. |
| Volume: |
107 |
| Issue: |
16 |
| Pages: |
7598-603 |
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•
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| First Author: |
Francou A |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
Epithelial tension in the second heart field promotes mouse heart tube elongation. |
| Volume: |
8 |
|
| Pages: |
14770 |
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•
•
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| First Author: |
Liu Y |
| Year: |
2012 |
| Journal: |
Dev Biol |
| Title: |
β-Catenin stabilization in skeletal muscles, but not in motor neurons, leads to aberrant motor innervation of the muscle during neuromuscular development in mice. |
| Volume: |
366 |
| Issue: |
2 |
| Pages: |
255-67 |
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•
•
•
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| First Author: |
McCulley DJ |
| Year: |
2008 |
| Journal: |
Dev Dyn |
| Title: |
BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development. |
| Volume: |
237 |
| Issue: |
11 |
| Pages: |
3200-9 |
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•
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•
•
•
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| Publication |
| First Author: |
Seya D |
| Year: |
2021 |
| Journal: |
Dev Growth Differ |
| Title: |
A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis. |
| Volume: |
63 |
| Issue: |
1 |
| Pages: |
82-92 |
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•
•
•
•
•
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| Publication |
| First Author: |
Delgado I |
| Year: |
2014 |
| Journal: |
Hepatology |
| Title: |
GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice. |
| Volume: |
59 |
| Issue: |
6 |
| Pages: |
2358-70 |
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•
•
•
•
•
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| Publication |
| First Author: |
Gensch N |
| Year: |
2008 |
| Journal: |
Development |
| Title: |
Different autonomous myogenic cell populations revealed by ablation of Myf5-expressing cells during mouse embryogenesis. |
| Volume: |
135 |
| Issue: |
9 |
| Pages: |
1597-604 |
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•
•
•
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| Publication |
| First Author: |
Firulli BA |
| Year: |
2017 |
| Journal: |
Cardiovasc Res |
| Title: |
The HAND1 frameshift A126FS mutation does not cause hypoplastic left heart syndrome in mice. |
| Volume: |
113 |
| Issue: |
14 |
| Pages: |
1732-1742 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu W |
| Year: |
2017 |
| Journal: |
Sci Signal |
| Title: |
Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance. |
| Volume: |
10 |
| Issue: |
489 |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Briggs LE |
| Year: |
2016 |
| Journal: |
Dev Dyn |
| Title: |
Wnt/β-catenin and sonic hedgehog pathways interact in the regulation of the development of the dorsal mesenchymal protrusion. |
| Volume: |
245 |
| Issue: |
2 |
| Pages: |
103-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leung C |
| Year: |
2014 |
| Journal: |
J Am Heart Assoc |
| Title: |
Rac1 signaling is critical to cardiomyocyte polarity and embryonic heart development. |
| Volume: |
3 |
| Issue: |
5 |
| Pages: |
e001271 |
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•
•
•
•
•
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| Publication |
| First Author: |
Hasumi H |
| Year: |
2012 |
| Journal: |
J Natl Cancer Inst |
| Title: |
Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN. |
| Volume: |
104 |
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22 |
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1750-64 |
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•
•
•
•
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| Publication |
| First Author: |
Wang X |
| Year: |
2017 |
| Journal: |
Dev Biol |
| Title: |
Endothelium in the pharyngeal arches 3, 4 and 6 is derived from the second heart field. |
| Volume: |
421 |
| Issue: |
2 |
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108-117 |
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•
•
•
•
|
| Publication |
| First Author: |
DÃaz Del Moral S |
| Year: |
2021 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Deletion of the Wilms' Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development. |
| Volume: |
9 |
|
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683861 |
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•
•
•
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| First Author: |
Arroyo N |
| Year: |
2021 |
| Journal: |
JCI Insight |
| Title: |
GATA4 induces liver fibrosis regression by deactivating hepatic stellate cells. |
| Volume: |
6 |
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23 |
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•
•
•
•
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| First Author: |
Huang X |
| Year: |
2022 |
| Journal: |
J Biol Chem |
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The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms. |
| Volume: |
298 |
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1 |
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•
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Delgado-OlguÃn P |
| Year: |
2012 |
| Journal: |
Nat Genet |
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Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis. |
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Leung C |
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2015 |
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J Am Heart Assoc |
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Rac1 Signaling Is Required for Anterior Second Heart Field Cellular Organization and Cardiac Outflow Tract Development. |
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1 |
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•
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| First Author: |
Zhao K |
| Year: |
2022 |
| Journal: |
Development |
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LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. |
| Volume: |
149 |
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6 |
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•
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Zheng M |
| Year: |
2021 |
| Journal: |
Int J Mol Sci |
| Title: |
Bmp Signaling Regulates Hand1 in a Dose-Dependent Manner during Heart Development. |
| Volume: |
22 |
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18 |
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•
•
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Lee KY |
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EMBO Mol Med |
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Compound loss of muscleblind-like function in myotonic dystrophy. |
| Volume: |
5 |
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12 |
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1887-900 |
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•
•
•
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| Publication |
| First Author: |
Thomas JD |
| Year: |
2017 |
| Journal: |
Genes Dev |
| Title: |
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy. |
| Volume: |
31 |
| Issue: |
11 |
| Pages: |
1122-1133 |
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•
•
•
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| First Author: |
Wu J |
| Year: |
2011 |
| Journal: |
Cell Metab |
| Title: |
The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex. |
| Volume: |
13 |
| Issue: |
2 |
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160-9 |
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•
•
•
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| Publication |
| First Author: |
Engleka KA |
| Year: |
2012 |
| Journal: |
Circ Res |
| Title: |
Islet1 derivatives in the heart are of both neural crest and second heart field origin. |
| Volume: |
110 |
| Issue: |
7 |
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922-6 |
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•
•
•
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| First Author: |
Jang C |
| Year: |
2016 |
| Journal: |
Nat Med |
| Title: |
A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. |
| Volume: |
22 |
| Issue: |
4 |
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•
•
•
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| First Author: |
Dubé JJ |
| Year: |
2015 |
| Journal: |
Am J Physiol Endocrinol Metab |
| Title: |
Adipose triglyceride lipase deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in mice. |
| Volume: |
308 |
| Issue: |
10 |
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E879-90 |
|
•
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| Publication |
| First Author: |
Nishino T |
| Year: |
2023 |
| Journal: |
Nat Cardiovasc Res |
| Title: |
Single Cell Multimodal Analyses Reveal Epigenomic and Transcriptomic Basis for Birth Defects in Maternal Diabetes. |
| Volume: |
2 |
| Issue: |
12 |
| Pages: |
1190-1203 |
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•
•
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| Publication |
| First Author: |
Edwards W |
| Year: |
2023 |
| Journal: |
Development |
| Title: |
The Tbx20-TLE interaction is essential for the maintenance of the second heart field. |
| Volume: |
150 |
| Issue: |
21 |
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•
•
•
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| Publication |
| First Author: |
Xu M |
| Year: |
2021 |
| Journal: |
Development |
| Title: |
The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. |
| Volume: |
148 |
| Issue: |
8 |
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•
•
•
•
|
| Genotype |
| Symbol: |
Bmp4/? Gt(ROSA)26Sor/? Tg(Mef2c-cre)2Blk/? |
| Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Rac1/Rac1 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mef2c-cre)2Blk/? |
| Background: |
involves: 129 * BALB/c * C57BL/6 * C57BL/6J |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kmt2d/Kmt2d<+> Tg(Mef2c-cre)2Blk/? |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kmt2d/Kmt2d Tg(Mef2c-cre)2Blk/? |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Smo/Smo Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mef2c-cre)2Blk/? |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mef2c-cre)2Blk/? Wdr1/Wdr1<+> |
| Background: |
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mef2c-cre)2Blk/? Wdr1/Wdr1 |
| Background: |
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
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| Publication |
| First Author: |
Kao HY |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Mechanism for nucleocytoplasmic shuttling of histone deacetylase 7. |
| Volume: |
276 |
| Issue: |
50 |
| Pages: |
47496-507 |
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•
•
•
•
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| Publication |
| First Author: |
Yan C |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains. |
| Volume: |
276 |
| Issue: |
14 |
| Pages: |
10870-8 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Wang DZ |
| Year: |
1999 |
| Journal: |
Development |
| Title: |
Requirement of a novel gene, Xin, in cardiac morphogenesis. |
| Volume: |
126 |
| Issue: |
6 |
| Pages: |
1281-94 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Boccanegra B |
| Year: |
2023 |
| Journal: |
Front Immunol |
| Title: |
Growth hormone secretagogues modulate inflammation and fibrosis in mdx mouse model of Duchenne muscular dystrophy. |
| Volume: |
14 |
|
| Pages: |
1119888 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jung-Ching Lin J |
| Year: |
2005 |
| Journal: |
J Med Sci |
| Title: |
Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin. |
| Volume: |
25 |
| Issue: |
5 |
| Pages: |
215-222 |
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•
•
•
•
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| Publication |
| First Author: |
Wilson EM |
| Year: |
2004 |
| Journal: |
Mol Biol Cell |
| Title: |
Permissive roles of phosphatidyl inositol 3-kinase and Akt in skeletal myocyte maturation. |
| Volume: |
15 |
| Issue: |
2 |
| Pages: |
497-505 |
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•
•
•
•
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| Publication |
| First Author: |
Caño-Carrillo S |
| Year: |
2024 |
| Journal: |
Int J Mol Sci |
| Title: |
Mef2c- and Nkx2-5-Divergent Transcriptional Regulation of Chick WT1_76127 and Mouse Gm14014 lncRNAs and Their Implication in Epicardial Cell Migration. |
| Volume: |
25 |
| Issue: |
23 |
|
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•
•
•
•
•
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| Publication |
| First Author: |
Celona B |
| Year: |
2017 |
| Journal: |
Elife |
| Title: |
Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106. |
| Volume: |
6 |
|
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•
•
•
•
•
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| Publication |
| First Author: |
Roux M |
| Year: |
2015 |
| Journal: |
Dev Biol |
| Title: |
Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development. |
| Volume: |
406 |
| Issue: |
2 |
| Pages: |
247-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liang D |
| Year: |
2014 |
| Journal: |
Dev Biol |
| Title: |
Mesodermal expression of integrin α5β1 regulates neural crest development and cardiovascular morphogenesis. |
| Volume: |
395 |
| Issue: |
2 |
| Pages: |
232-44 |
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•
•
•
•
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| Publication |
| First Author: |
Peterson JC |
| Year: |
2018 |
| Journal: |
Dis Model Mech |
| Title: |
Bicuspid aortic valve formation: Nos3 mutation leads to abnormal lineage patterning of neural crest cells and the second heart field. |
| Volume: |
11 |
| Issue: |
10 |
|
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•
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| Publication |
| First Author: |
Eley L |
| Year: |
2024 |
| Journal: |
Dis Model Mech |
| Title: |
eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling. |
| Volume: |
17 |
| Issue: |
1 |
|
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•
•
•
•
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| Publication |
| First Author: |
El Robrini N |
| Year: |
2016 |
| Journal: |
Dev Dyn |
| Title: |
Cardiac outflow morphogenesis depends on effects of retinoic acid signaling on multiple cell lineages. |
| Volume: |
245 |
| Issue: |
3 |
| Pages: |
388-401 |
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•
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•
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| Publication |
| First Author: |
Suzuki A |
| Year: |
2018 |
| Journal: |
Development |
| Title: |
WNT/β-catenin signaling plays a crucial role in myoblast fusion through regulation of nephrin expression during development. |
| Volume: |
145 |
| Issue: |
23 |
|
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•
•
•
•
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| Publication |
| First Author: |
Keenan ID |
| Year: |
2012 |
| Journal: |
FEBS Lett |
| Title: |
Origin of non-cardiac endothelial cells from an Isl1+ lineage. |
| Volume: |
586 |
| Issue: |
13 |
| Pages: |
1790-4 |
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| Publication |
| First Author: |
Li S |
| Year: |
2005 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice. |
| Volume: |
102 |
| Issue: |
4 |
| Pages: |
1082-7 |
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•
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| Publication |
| First Author: |
Hu J |
| Year: |
2018 |
| Journal: |
Dev Biol |
| Title: |
WDR1-regulated actin dynamics is required for outflow tract and right ventricle development. |
| Volume: |
438 |
| Issue: |
2 |
| Pages: |
124-137 |
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| Publication |
| First Author: |
Gittenberger-de Groot AC |
| Year: |
2020 |
| Journal: |
PLoS One |
| Title: |
Pulmonary ductal coarctation and left pulmonary artery interruption; pathology and role of neural crest and second heart field during development. |
| Volume: |
15 |
| Issue: |
5 |
| Pages: |
e0228478 |
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| Publication |
| First Author: |
Hoffmann AD |
| Year: |
2014 |
| Journal: |
PLoS Genet |
| Title: |
Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation. |
| Volume: |
10 |
| Issue: |
10 |
| Pages: |
e1004604 |
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| Publication |
| First Author: |
Plummer NW |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Development of the mammalian axial skeleton requires signaling through the Gα(i) subfamily of heterotrimeric G proteins. |
| Volume: |
109 |
| Issue: |
52 |
| Pages: |
21366-71 |
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| First Author: |
Blondelle J |
| Year: |
2019 |
| Journal: |
Commun Biol |
| Title: |
Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism. |
| Volume: |
2 |
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| Pages: |
178 |
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