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Search results 1501 to 1600 out of 4141 for Mtor

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Type Details Score
Publication
25339766 | J:219230
First Author: Teng CF
Year: 2015
Journal: J Virol
Title: Activation of ATP citrate lyase by mTOR signal induces disturbed lipid metabolism in hepatitis B virus pre-S2 mutant tumorigenesis.
Volume: 89
Issue: 1
Pages: 605-14
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Publication
28963352 | J:252286
First Author: Malone CF
Year: 2017
Journal: Cancer Discov
Title: mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors.
Volume: 7
Issue: 12
Pages: 1450-1463
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Publication
25436981 | J:317517
First Author: Andrade-Vieira R
Year: 2014
Journal: Oncotarget
Title: Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss.
Volume: 5
Issue: 24
Pages: 12738-52
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Publication
23246963 | J:204879
First Author: Montero JC
Year: 2014
Journal: Oncogene
Title: Active kinase profiling, genetic and pharmacological data define mTOR as an important common target in triple-negative breast cancer.
Volume: 33
Issue: 2
Pages: 148-56
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Publication
22859719 | J:194652
First Author: Sun ZJ
Year: 2012
Journal: Clin Cancer Res
Title: Chemopreventive and chemotherapeutic actions of mTOR inhibitor in genetically defined head and neck squamous cell carcinoma mouse model.
Volume: 18
Issue: 19
Pages: 5304-13
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Publication
24466367 | J:264441
First Author: Mohammed A
Year: 2013
Journal: Transl Oncol
Title: Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling.
Volume: 6
Issue: 6
Pages: 649-59
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Publication
32873626 | J:300748
First Author: Feng G
Year: 2020
Journal: Mol Cancer Res
Title: G-Protein-Coupled Estrogen Receptor 1 Promotes Gender Disparities in Hepatocellular Carcinoma via Modulation of SIN1 and mTOR Complex 2 Activity.
Volume: 18
Issue: 12
Pages: 1863-1875
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Interaction Experiment
Takai H (2010)
Description: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
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Interaction Experiment
Linares JF (2013)
Description: K63 Polyubiquitination and Activation of mTOR by the p62-TRAF6 Complex in Nutrient-Activated Cells.
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Interaction Experiment
Sofer A (2005)
Description: Regulation of mTOR and cell growth in response to energy stress by REDD1.
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Interaction Experiment
Meffre J (2012)
Description: 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.
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Interaction Experiment
Zhang H (2003)
Description: Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR.
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Interaction Experiment
Guo F (2013)
Description: mTOR regulates DNA damage response through NF-B-mediated FANCD2 pathway in hematopoietic cells.
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Interaction Experiment
Smithson LJ (2016)
Description: Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.
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Publication
27879318 | J:238485
First Author: Dai Q
Year: 2017
Journal: J Biol Chem
Title: Inactivation of Regulatory-associated Protein of mTOR (Raptor)/Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in Osteoclasts Increases Bone Mass by Inhibiting Osteoclast Differentiation in Mice.
Volume: 292
Issue: 1
Pages: 196-204
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Protein
K7N6X2
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: false
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Publication
16886599 | J:116033
First Author: Affara NI
Year: 2006
Journal: Anticancer Res
Title: Activation of Akt and mTOR in CD34+/K15+ keratinocyte stem cells and skin tumors during multi-stage mouse skin carcinogenesis.
Volume: 26
Issue: 4B
Pages: 2805-20
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Publication
17178906 | J:119075
First Author: Teis D
Year: 2006
Journal: J Cell Biol
Title: p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis.
Volume: 175
Issue: 6
Pages: 861-8
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HT Experiment
E-GEOD-67723 | Network analysis of gene expression in mice provides new evidence of involvement of the mTOR pathway in antipsychotic-induced extrapyramidal symptoms
Series Id: GSE67723
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
22457330 | J:234588
First Author: Menon S
Year: 2012
Journal: Sci Signal
Title: Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice.
Volume: 5
Issue: 217
Pages: ra24
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Publication
29626114 | J:261588
First Author: Chiang ACA
Year: 2018
Journal: J Exp Med
Title: Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice.
Volume: 215
Issue: 5
Pages: 1349-1364
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Publication
34216687 | J:310246
 
First Author: Meeusen B
Year: 2021
Journal: Cancer Lett
Title: PPP2R4 dysfunction promotes KRAS-mutant lung adenocarcinoma development and mediates opposite responses to MEK and mTOR inhibition.
Volume: 520
Pages: 57-67
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Publication
16298682 | J:104013
First Author: Ha T
Year: 2005
Journal: Free Radic Biol Med
Title: Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo.
Volume: 39
Issue: 12
Pages: 1570-80
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Publication
27942591 | J:290948
First Author: Agarwal S
Year: 2016
Journal: JCI Insight
Title: mTOR inhibition and BMP signaling act synergistically to reduce muscle fibrosis and improve myofiber regeneration.
Volume: 1
Issue: 20
Pages: e89805
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Publication
25931147 | J:223322
First Author: Malla R
Year: 2015
Journal: Biochem Pharmacol
Title: Genetic ablation of PRAS40 improves glucose homeostasis via linking the AKT and mTOR pathways.
Volume: 96
Issue: 1
Pages: 65-75
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Publication
29514215 | J:261411
First Author: Danyukova T
Year: 2018
Journal: Hum Mol Genet
Title: Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation.
Volume: 27
Issue: 10
Pages: 1711-1722
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Publication
22539746 | J:186679
First Author: Thomas HE
Year: 2012
Journal: Sci Transl Med
Title: mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.
Volume: 4
Issue: 139
Pages: 139ra84
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Publication
26523512 | J:233201
First Author: Zhang D
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Propofol promotes cell apoptosis via inhibiting HOTAIR mediated mTOR pathway in cervical cancer.
Volume: 468
Issue: 4
Pages: 561-7
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Publication
29217683 | J:258298
First Author: Steinmetz AB
Year: 2018
Journal: J Neurosci
Title: Insulin-Like Growth Factor II Targets the mTOR Pathway to Reverse Autism-Like Phenotypes in Mice.
Volume: 38
Issue: 4
Pages: 1015-1029
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Publication
33353667 | J:322044
First Author: Lin R
Year: 2021
Journal: Biol Psychiatry
Title: Persistently Elevated mTOR Complex 1-S6 Kinase 1 Disrupts DARPP-32-Dependent D1 Dopamine Receptor Signaling and Behaviors.
Volume: 89
Issue: 11
Pages: 1058-1072
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Allele
Lamtor3<+> | MGI:2435887
   
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 3; wild type
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Allele
Lamtor5<+> | MGI:3048632
   
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5; wild type
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Allele
Mlst8<+> | MGI:3605342
 
Name: MTOR associated protein, LST8 homolog (S. cerevisiae); wild type
Allele Type: Not Specified
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Allele
Lamtor2<+> | MGI:3605398
 
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 2; wild type
Allele Type: Not Specified
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Allele
Lamtor1<+> | MGI:5430806
 
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 1; wild type
Allele Type: Not Specified
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Allele
Lamtor4<+> | MGI:5442406
 
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 4; wild type
Allele Type: Not Specified
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Protein Coding Gene
MGP_CAROLIEiJ_G0031628 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034192 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034099 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034166 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033877 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1921597 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034686 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033204 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033850 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034006 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033949 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034095 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033996 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034704 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023226 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032746 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5788875
Assay Type: RT-PCR
Annotation Date: 2016-08-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5788896
Age: postnatal adult
Image: 1
Specimen Label: Brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5788875
Assay Type: RT-PCR
Annotation Date: 2016-08-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5788896
Age: postnatal adult
Image: 1
Specimen Label: Kidney
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5788875
Assay Type: RT-PCR
Annotation Date: 2016-08-16
Strength: Present
Sex: Male
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5788896
Age: postnatal adult
Image: 1
Specimen Label: Cerebellum
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5788875
Assay Type: RT-PCR
Annotation Date: 2016-08-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5788896
Age: postnatal adult
Image: 1
Specimen Label: Liver
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5788875
Assay Type: RT-PCR
Annotation Date: 2016-08-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5788896
Age: postnatal adult
Image: 1
Specimen Label: Spinal Cord
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5788875
Assay Type: RT-PCR
Annotation Date: 2016-08-16
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5788896
Age: postnatal adult
Image: 1
Specimen Label: Lung
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5788875
Assay Type: RT-PCR
Annotation Date: 2016-08-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5788896
Age: postnatal adult
Image: 1
Specimen Label: Testis
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5788875
Assay Type: RT-PCR
Annotation Date: 2016-08-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5788896
Age: postnatal adult
Image: 1
Specimen Label: Spleen
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5788875
Assay Type: RT-PCR
Annotation Date: 2016-08-16
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5788896
Age: postnatal adult
Image: 1
Specimen Label: Heart
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:4416902
Assay Type: RNA in situ
Annotation Date: 2023-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7549160
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5788880
Assay Type: RNA in situ
Annotation Date: 2016-08-16
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5788903
Age: postnatal adult
Image: 1C right panel
Specimen Label: 1C right panel
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5788880
Assay Type: RNA in situ
Annotation Date: 2016-08-16
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5788903
Age: postnatal adult
Image: 1C middle panel
Note: Low level of expression, although expression in hippocampus is apparent.
Specimen Label: 1C middle panel
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5788880
Assay Type: RNA in situ
Annotation Date: 2016-08-16
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1603922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5788903
Age: embryonic day 14.5
Image: 1C left panel
Note: Authors state expression virtually undetectable at this developmental time point.
Specimen Label: 1C left panel
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4416902
Assay Type: RNA in situ
Annotation Date: 2023-11-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7549160
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
20543138 | J:175339
First Author: Kantidakis T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1.
Volume: 107
Issue: 26
Pages: 11823-8
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Publication
16567633 | J:108293
First Author: Shillingford JM
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease.
Volume: 103
Issue: 14
Pages: 5466-71
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Publication
12504590 | J:81245
First Author: Onda H
Year: 2002
Journal: Mol Cell Neurosci
Title: Tsc2 null murine neuroepithelial cells are a model for human tuber giant cells, and show activation of an mTOR pathway.
Volume: 21
Issue: 4
Pages: 561-74
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Publication
31939616 | J:296757
First Author: Huang Q
Year: 2020
Journal: Int J Mol Med
Title: Loss of LAMTOR1 in pancreatic β‑cells increases glucose‑stimulated insulin secretion in mice.
Volume: 45
Issue: 1
Pages: 23-32
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Publication
28723898 | J:253142
First Author: Zhang CS
Year: 2017
Journal: Nature
Title: Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.
Volume: 548
Issue: 7665
Pages: 112-116
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Publication
28223137 | -
First Author: Tam RC
Year: 2017
Journal: Exp Cell Res
Title: Human CLEC16A regulates autophagy through modulating mTOR activity.
Volume: 352
Issue: 2
Pages: 304-312
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Publication
23982838 | J:214500
First Author: Chung SH
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Laser capture microdissection-directed profiling of glycolytic and mTOR pathways in areas of selectively ablated Müller cells in the murine retina.
Volume: 54
Issue: 10
Pages: 6578-85
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Publication
27731330 | J:242601
 
First Author: Kimura T
Year: 2016
Journal: Nat Commun
Title: Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals.
Volume: 7
Pages: 13130
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Publication
31337951 | J:293660
First Author: Yang QC
Year: 2019
Journal: Int J Med Sci
Title: Increased Expression of LAMTOR5 Predicts Poor Prognosis and Is Associated with Lymph Node Metastasis of Head and Neck Squamous Cell Carcinoma.
Volume: 16
Issue: 6
Pages: 783-792
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Publication
19446321 | -
First Author: Peterson TR
Year: 2009
Journal: Cell
Title: DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival.
Volume: 137
Issue: 5
Pages: 873-86
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Protein
Q9JHS3
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0025670 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027919 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027876 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027842 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027889 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027618 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1929467 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028332 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027734 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027844 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027733 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028390 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026798 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027154 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027119 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026625 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
17254543 | J:123362
First Author: Brahma A
Year: 2007
Journal: Arch Biochem Biophys
Title: Regulation of protein phosphorylation within the MKK1-ERK2 complex by MP1 and the MP1*P14 heterodimer.
Volume: 460
Issue: 1
Pages: 85-91
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