|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1501 to 1600 out of 1625 for Nfe2l2

<< First    < Previous  |  Next >    Last >>
0.029s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein
Q60795
Organism: Mus musculus/domesticus
Length: 597  
Fragment?: false
•
•
•
•
•
Allele
Keap1<tm2Mym> | MGI:3611748
Name: kelch-like ECH-associated protein 1; targeted mutation 2, Masayuki Yamamoto
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph
•
•
•
•
•
Publication
29486298 | J:268280
 
First Author: Rizzi N
Year: 2018
Journal: Neurobiol Dis
Title: In vivo imaging of early signs of dopaminergic neuronal death in an animal model of Parkinson's disease.
Volume: 114
Pages: 74-84
•
•
•
•
•
Protein Coding Gene
MGI:99523 | Prdx1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
P35700
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: false
•
•
•
•
•
Publication
27899606 | J:250245
First Author: Rizzi N
Year: 2017
Journal: Nucleic Acids Res
Title: Identification of novel loci for the generation of reporter mice.
Volume: 45
Issue: 6
Pages: e37
•
•
•
•
•
Strain
MGI:6279208 | B6.129P2-Keap1<tm2Mym>
Attribute String: targeted mutation, mutant strain, congenic
•
•
•
•
•
Publication
33149211 | J:300417
First Author: Tamatam CM
Year: 2020
Journal: Sci Rep
Title: Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice.
Volume: 10
Issue: 1
Pages: 19034
•
•
•
•
•
Publication
33318486 | J:303385
First Author: Oishi T
Year: 2020
Journal: NPJ Aging Mech Dis
Title: Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss.
Volume: 6
Issue: 1
Pages: 14
•
•
•
•
•
Publication
24224011 | J:209321
First Author: Xu J
Year: 2013
Journal: PLoS One
Title: Keap1-knockdown decreases fasting-induced fatty liver via altered lipid metabolism and decreased fatty acid mobilization from adipose tissue.
Volume: 8
Issue: 11
Pages: e79841
•
•
•
•
•
Allele
Tg(Actb-Nfe2l2,-EGFP)CMVSwnr | MGI:6095171
Name: transgene insertion CMV, Sabine Werner
Allele Type: Transgenic
Attribute String: Conditional ready, Constitutively active, Inserted expressed sequence, Modified isoform(s), Reporter
•
•
•
•
•
Genotype
Genotype
Symbol: Keap1/Keap1
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Keap1/Keap1<+>
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Keap1/Keap1
Background: B6.129P2-Keap1
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Protein Coding Gene
MGI:1336173 | Prkaa2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q8BRK8
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
•
•
•
•
•
Publication
31257023 | J:278348
First Author: Lignitto L
Year: 2019
Journal: Cell
Title: Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1.
Volume: 178
Issue: 2
Pages: 316-329.e18
•
•
•
•
•
Publication
37848024 | J:343571
First Author: Kim HJ
Year: 2023
Journal: Neuron
Title: Deep scRNA sequencing reveals a broadly applicable Regeneration Classifier and implicates antioxidant response in corticospinal axon regeneration.
Volume: 111
Issue: 24
Pages: 3953-3969.e5
•
•
•
•
•
Genotype
Genotype
Symbol: Keap1/Keap1
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Protein Coding Gene
MGI:1861437 | Gsk3b
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q9WV60
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
•
•
•
•
•
Publication
34298930 | J:322205
 
First Author: Eswaran S
Year: 2021
Journal: Int J Mol Sci
Title: Upregulation of Anti-Oxidative Stress Response Improves Metabolic Changes in L-Selectin-Deficient Mice but Does Not Prevent NAFLD Progression or Fecal Microbiota Shifts.
Volume: 22
Issue: 14
•
•
•
•
•
Publication
33857757 | J:337886
 
First Author: Onoki T
Year: 2021
Journal: Redox Biol
Title: Skeletal muscle-specific Keap1 disruption modulates fatty acid utilization and enhances exercise capacity in female mice.
Volume: 43
Pages: 101966
•
•
•
•
•
Strain
MGI:6279207 | B6.Cg-Keap1<tm2Mym> Speer6-ps1<Tg(Alb-cre)21Mgn>
Attribute String: targeted mutation, mutant strain, congenic
•
•
•
•
•
Genotype
Genotype
Symbol: Keap1/Keap1<+> Speer6-ps1/Speer6-ps1<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Keap1/Keap1 Speer6-ps1/Speer6-ps1<+>
Background: B6.Cg-Keap1 Speer6-ps1
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Publication
26391655 | J:262263
First Author: Grootaert MO
Year: 2015
Journal: Autophagy
Title: Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis.
Volume: 11
Issue: 11
Pages: 2014-2032
•
•
•
•
•
Publication
24253037 | J:207184
First Author: Cherry AD
Year: 2014
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor γ co-activator 1-α as a critical co-activator of the murine hepatic oxidative stress response and mitochondrial biogenesis in Staphylococcus aureus sepsis.
Volume: 289
Issue: 1
Pages: 41-52
•
•
•
•
•
Publication
36136587 | J:331715
 
First Author: Zhang W
Year: 2022
Journal: J Clin Invest
Title: SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity.
Volume: 132
Issue: 22
•
•
•
•
•
Publication
28334913 | J:242322
First Author: Moujalled D
Year: 2017
Journal: Hum Mol Genet
Title: TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.
Volume: 26
Issue: 9
Pages: 1732-1746
•
•
•
•
•
Publication
34870542 | J:317234
   
First Author: Chao X
Year: 2021
Journal: Autophagy
Title: An unexpected tumor suppressor role of SQSTM1/p62 in liver tumorigenesis.
Pages: 1-3
•
•
•
•
•
Publication
33618031 | J:314120
First Author: Wang H
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas.
Volume: 12
Issue: 1
Pages: 199-228
•
•
•
•
•
Publication
26933443 | J:356011
 
First Author: Ghosh S
Year: 2016
Journal: Nutr Metab (Lond)
Title: Short chain acyl-CoA dehydrogenase deficiency and short-term high-fat diet perturb mitochondrial energy metabolism and transcriptional control of lipid-handling in liver.
Volume: 13
Pages: 17
•
•
•
•
•
Publication
39083201 | J:357530
First Author: Ma X
Year: 2024
Journal: Sci China Life Sci
Title: The single-cell transcriptomic landscape of the topological differences in mammalian auditory receptors.
Volume: 67
Issue: 11
Pages: 2398-2410
•
•
•
•
•
Protein Coding Gene
MGI:1098280 | Crebbp
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
P45481
Organism: Mus musculus/domesticus
Length: 2441  
Fragment?: false
•
•
•
•
•
Publication
27663899 | J:237849
First Author: Jeong Y
Year: 2017
Journal: Cancer Discov
Title: Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance.
Volume: 7
Issue: 1
Pages: 86-101
•
•
•
•
•
Publication
24675090 | J:215356
First Author: Kensler KH
Year: 2014
Journal: Toxicol Sci
Title: Genetic or pharmacologic activation of Nrf2 signaling fails to protect against aflatoxin genotoxicity in hypersensitive GSTA3 knockout mice.
Volume: 139
Issue: 2
Pages: 293-300
•
•
•
•
•
Publication
24769730 | J:229860
First Author: Cazanave SC
Year: 2014
Journal: Cell Death Differ
Title: Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis.
Volume: 21
Issue: 8
Pages: 1303-12
•
•
•
•
•
Genotype
Genotype
Symbol: Keap1/Keap1 Speer6-ps1/Speer6-ps1<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Keap1/Keap1 Pten/Pten Speer6-ps1/Speer6-ps1<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Protein Coding Gene
MGI:1891829 | Rbx1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1276116 | Ep300
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
B2RWS6
Organism: Mus musculus/domesticus
Length: 2412  
Fragment?: false
•
•
•
•
•
Protein
P62878
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: false
•
•
•
•
•
Publication
35013236 | J:321355
First Author: Jiwaji Z
Year: 2022
Journal: Nat Commun
Title: Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
Volume: 13
Issue: 1
Pages: 135
•
•
•
•
•
Genotype
Genotype
Symbol: Keap1/Keap1 Nfe2l2/Nfe2l2 Pten/Pten Speer6-ps1/Speer6-ps1<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Keap1/Keap1 Nfe2l2/Nfe2l2<+> Pten/Pten Speer6-ps1/Speer6-ps1<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Protein Coding Gene
MGI:103575 | Skp1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1349658 | Cul1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q9WTX6
Organism: Mus musculus/domesticus
Length: 776  
Fragment?: false
•
•
•
•
•
Protein
Q9WTX5
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: false
•
•
•
•
•
Publication
35425962 | J:324033
First Author: Yousefi M
Year: 2022
Journal: Cancer Res
Title: Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities.
Volume: 82
Issue: 8
Pages: 1589-1602
•
•
•
•
•
Protein Coding Gene
MGI:1917497 | Psmd1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:104880 | Psmb6
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1916327 | Psmd11
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1347014 | Psmb3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:98858 | Psmd3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:105047 | Psmc5
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1914247 | Psmd12
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1347006 | Psma6
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:104883 | Psma3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:106054 | Psmc1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:104885 | Psma2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1913663 | Psmd6
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1914339 | Psmc6
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1194513 | Psmb5
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1096584 | Psmd2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:104884 | Psmb1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:107637 | Psmb7
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1913284 | Psmd14
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1098754 | Psmc3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1347070 | Psma7
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1929289 | Adrm1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1098257 | Psmb4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1347009 | Psma5
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1347045 | Psmb2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:109555 | Psmc2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1346093 | Psmc4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1888669 | Psmd8
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1347005 | Psma1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1345192 | Psmd13
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1351511 | Psmd7
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1347060 | Psma4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q9JKV1
Organism: Mus musculus/domesticus
Length: 407  
Fragment?: false
•
•
•
•
•
Protein
Q9R1P1
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: false
•
•
•
•
•
Protein
P99026
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: false
•
•
•
•
•
Protein
Q60692
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
•
•
•
•
•
Protein
P70195
Organism: Mus musculus/domesticus
Length: 277  
Fragment?: false
•
•
•
•
•
Protein
P46471
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: false
•
•
•
•
•
Protein
Q9R1P0
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
•
•
•
•
•
Protein
Q9WVJ2
Organism: Mus musculus/domesticus
Length: 376  
Fragment?: false
•
•
•
•
•
Protein
Q8BG32
Organism: Mus musculus/domesticus
Length: 422  
Fragment?: false
•
•
•
•
•
Protein
Q9Z2U0
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
•
•
•
•
•
Protein
P54775
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: false
•
•
•
•
•
Protein
P14685
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
•
•
•
•
•
Protein
Q9Z2U1
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: false
•
•
•
•
•
Protein
Q9R1P3
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
•
•
•
•
•
Protein
Q99JI4
Organism: Mus musculus/domesticus
Length: 389  
Fragment?: false
•
•
•
•
•
Protein
O70435
Organism: Mus musculus/domesticus
Length: 255  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom