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Search results 1501 to 1600 out of 1665 for Nkx2-2

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Type Details Score
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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HT Experiment
E-MTAB-3350 | Gene expression profiling of wild-type, Nkx2.2 null, NeuroD null and Nkx2.2/NeuroD double KO E13.5 pancreata
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE80444 | RNA-Seq analysis of E15.5 pancreas of both whole body Nkx2.2 mutant embryos and endocrine progenitor specific Nkx2.2 mutant embryos
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE79723 | RNA-Seq analysis of the pancreatic islets of beta cell specific adult Nkx2.2 mutant mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
E-MTAB-3353 | Whole transcriptome analysis of pancreatic ghrelin cells in WT and Nkx2.2 KO mouse embryo
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-78902 | RNAseq analysis of the colon of intestine-specific adult Nkx2.2 mutant mice
Series Id: GSE78902
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Sample
Nkx2-2 NULL Embryos Rep2
 
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Curation Status: Curated
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
10818213 | J:80573
First Author: Wang CC
Year: 2000
Journal: Mamm Genome
Title: Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals.
Volume: 11
Issue: 6
Pages: 466-8
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Publication
7649395 | J:28311
First Author: Neubüser A
Year: 1995
Journal: Dev Biol
Title: Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1.
Volume: 170
Issue: 2
Pages: 701-16
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Publication
8358169 | J:12925
First Author: Wallin J
Year: 1993
Journal: Mamm Genome
Title: A new Pax gene, Pax-9, maps to mouse chromosome 12.
Volume: 4
Issue: 7
Pages: 354-8
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Publication
11452312 | -
First Author: Dann CE
Year: 2001
Journal: Nature
Title: Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.
Volume: 412
Issue: 6842
Pages: 86-90
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Publication
10938085 | J:65512
First Author: Watada H
Year: 2000
Journal: J Biol Chem
Title: Transcriptional and translational regulation of beta-cell differentiation factor Nkx6.1.
Volume: 275
Issue: 44
Pages: 34224-30
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Protein
P97299
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
11042159 | J:68323
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
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Publication
10349636 | J:80645
 
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
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Publication
11076861 | J:68324
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
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Publication
16141073 | -
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
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Protein
Q8K3N8
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: true
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Protein
Q3UUM9
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
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Protein
Q9JKR0
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: true
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Protein
Q3UI35
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
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Protein
Q3URZ4
Organism: Mus musculus/domesticus
Length: 273  
Fragment?: false
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Publication
10656762 | J:60407
First Author: Ladher RK
Year: 2000
Journal: Dev Biol
Title: Cloning and expression of the Wnt antagonists Sfrp-2 and Frzb during chick development.
Volume: 218
Issue: 2
Pages: 183-98
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Publication
18322270 | -
First Author: Bovolenta P
Year: 2008
Journal: J Cell Sci
Title: Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease.
Volume: 121
Issue: Pt 6
Pages: 737-46
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Publication
17471511 | -
First Author: Bhat RA
Year: 2007
Journal: J Cell Biochem
Title: Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function.
Volume: 102
Issue: 6
Pages: 1519-28
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Protein Domain
IPR041764 | SFRP2_CRD
Type: Domain
Description: The cysteine-rich-domain (CRD) is an essential part of the secreted frizzled related protein 2 (SFRP2), which has a role in development of the neural system, eyes, muscles and limbs. As a Wnt antagonist, SFRP2 regulates Nkx2.2 expression in the ventral spinal cord and anteroposterior axis elongation [].In general, SFRPs antagonize the activation of Wnt signaling by binding to the CRD domains of frizzled (Fz) proteins, thereby preventing Wnt proteins from binding to these receptors. SFRPs are also known to have functions unrelated to Wnt, as enhancers of procollagen cleavage by the TLD proteinases []. SFRPs and Fz proteins both contain CRD domains, but SFRPs lack the seven-pass transmembrane domain which is an integral part of Fzs [, ].
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Publication
9671740 | J:49339
First Author: Wilm B
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Targeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency.
Volume: 95
Issue: 15
Pages: 8692-7
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Publication
7875377 | J:23331
First Author: Dietrich S
Year: 1995
Journal: Dev Biol
Title: undulated phenotypes suggest a role of Pax-1 for the development of vertebral and extravertebral structures.
Volume: 167
Issue: 2
Pages: 529-48
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Publication
7607069 | J:20965
First Author: Timmons PM
Year: 1994
Journal: Development
Title: Expression and function of Pax 1 during development of the pectoral girdle.
Volume: 120
Issue: 10
Pages: 2773-85
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Allele
Pax1<Un-s> | MGI:1856225
 
Name: paired box 1; undulated short tail
Allele Type: Spontaneous
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Strain
MGI:3845979 | B6.CC57BR-Pax1<Un-s>
Attribute String: congenic, spontaneous mutation
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Publication
9719926 | J:48723
First Author: Sakharova NIu
Year: 1998
Journal: Genetika
Title: [Non-Mendelian inheritance of the Un(s) mutant gene in mice].
Volume: 34
Issue: 6
Pages: 816-24
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Publication
- | J:13667
 
First Author: Ferguson JM
Year: 1975
Journal: Mouse News Lett
Title: cy linkage.
Volume: 52
Pages: 31
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Publication
8026324 | J:18196
First Author: Wallin J
Year: 1994
Journal: Development
Title: The role of Pax-1 in axial skeleton development.
Volume: 120
Issue: 5
Pages: 1109-21
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Publication
- | J:13467
 
First Author: Blandova ZK
Year: 1967
Journal: Mouse News Lett
Title: Un
Volume: 36
Pages: 57
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Publication
- | J:13676
 
First Author: Blandova ZK
Year: 1975
Journal: Mouse News Lett
Title: Sut allelic with un
Volume: 52
Pages: 43
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Publication
8187635 | J:16332
First Author: Koseki H
Year: 1993
Journal: Development
Title: A role for Pax-1 as a mediator of notochordal signals during the dorsoventral specification of vertebrae.
Volume: 119
Issue: 3
Pages: 649-60
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Publication
8565834 | J:30819
First Author: Wallin J
Year: 1996
Journal: Development
Title: Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation.
Volume: 122
Issue: 1
Pages: 23-30
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Publication
34884468 | J:316482
 
First Author: Kouwenhoven WM
Year: 2021
Journal: Int J Mol Sci
Title: Nkx2.9 Contributes to Mid-Hindbrain Patterning by Regulation of mdDA Neuronal Cell-Fate and Repression of a Hindbrain-Specific Cell-Fate.
Volume: 22
Issue: 23
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Publication
18565209 | J:160742
 
First Author: Pla P
Year: 2008
Journal: Neural Dev
Title: Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors.
Volume: 3
Pages: 14
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Publication
29897331 | J:264162
   
First Author: Kaucka M
Year: 2018
Journal: Elife
Title: Signals from the brain and olfactory epithelium control shaping of the mammalian nasal capsule cartilage.
Volume: 7
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Publication
35294885 | J:324831
First Author: Lewis AE
Year: 2022
Journal: Cell Rep
Title: Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting.
Volume: 38
Issue: 11
Pages: 110510
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Publication
30045859 | J:263902
 
First Author: May M
Year: 2018
Journal: Biol Open
Title: Cell tracking in vitro reveals that the extracellular matrix glycoprotein Tenascin-C modulates cell cycle length and differentiation in neural stem/progenitor cells of the developing mouse spinal cord.
Volume: 7
Issue: 7
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Publication
15888661 | J:98336
First Author: Vernay B
Year: 2005
Journal: J Neurosci
Title: Otx2 regulates subtype specification and neurogenesis in the midbrain.
Volume: 25
Issue: 19
Pages: 4856-67
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Publication
23823474 | J:199239
First Author: Magnuson MA
Year: 2013
Journal: Cell Metab
Title: Pancreas-specific Cre driver lines and considerations for their prudent use.
Volume: 18
Issue: 1
Pages: 9-20
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Publication
18004726 | J:133545
First Author: Gupta A
Year: 2008
Journal: Prostate
Title: Neuroendocrine differentiation in the 12T-10 transgenic prostate mouse model mimics endocrine differentiation of pancreatic beta cells.
Volume: 68
Issue: 1
Pages: 50-60
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Publication
25191843 | J:355036
First Author: Maeda M
Year: 2014
Journal: PLoS One
Title: Transcriptome profiling of spinal muscular atrophy motor neurons derived from mouse embryonic stem cells.
Volume: 9
Issue: 9
Pages: e106818
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Publication
31038233 | J:277744
First Author: Ge X
Year: 2019
Journal: Glia
Title: Stage-dependent regulation of oligodendrocyte development and enhancement of myelin repair by dominant negative Master-mind 1 protein.
Volume: 67
Issue: 9
Pages: 1654-1666
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Publication
38419656 | J:345593
 
First Author: Rhodes CT
Year: 2024
Journal: Front Cell Neurosci
Title: Loss of Ezh2 in the medial ganglionic eminence alters interneuron fate, cell morphology and gene expression profiles.
Volume: 18
Pages: 1334244
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Allele
Tg(Nkx2-2*-cre)1Mtse | MGI:5290102
Name: transgene insertion 1, Michael P Matise
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Nkx2-1-icre/ERT2)1Kess | MGI:5430921
Name: transgene insertion 1, Nicoletta Kessaris
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Tg(Nkx2-2-cre/ERT2)1Wdr | MGI:5430928
Name: transgene insertion 1, William D Richardson
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Nkx2-2<tm4.1(cre/EGFP)Suss> | MGI:5538250
Name: NK2 homeobox 2; targeted mutation 4.1, Lori Sussel
Allele Type: Targeted
Attribute String: Null/knockout, Recombinase
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Strain
MGI:5617039 | B6.129S6(Cg)-Nkx2-2<tm4.1(cre/EGFP)Suss>/J
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Nkx2-2<tm1(icre)Aholz> | MGI:5818052
Name: NK2 homeobox 2; targeted mutation 1, Andreas Holz
Allele Type: Targeted
Attribute String: Null/knockout, Recombinase
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Allele
Nkx2-2<tm1.1(icre)Aholz> | MGI:5818053
Name: NK2 homeobox 2; targeted mutation 1.1, Andreas Holz
Allele Type: Targeted
Attribute String: Null/knockout, Recombinase
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Publication
30532991 | J:273404
First Author: Stancill JS
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences.
Volume: 316
Issue: 2
Pages: E196-E209
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Allele
Nkx2-1<em1(cre/ERT2)Smoc> | MGI:6728813
Name: NK2 homeobox 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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Allele
Nkx2-2<tm6.1(Ccre,Nkk2-2)Suss> | MGI:6780118
Name: NK2 homeobox 2; targeted mutation 6.1, Lori Sussel
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Gt(ROSA)26Sor<tm14(Rr209*-lacZ)Amc> | MGI:7327544
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 14, Andrew P McMahon
Allele Type: Targeted
Attribute String: Reporter
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Allele
Gt(ROSA)26Sor<tm12(Rr209-lacZ)Amc> | MGI:7327534
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 12, Andrew P McMahon
Allele Type: Targeted
Attribute String: Reporter
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Allele
Gt(ROSA)26Sor<tm13(Rr209-lacZ/GFP)Amc> | MGI:7327535
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 13, Andrew P McMahon
Allele Type: Targeted
Attribute String: Reporter
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Allele
Tg(Rr209-lacZ)3e.1Mtse | MGI:7327549
Name: transgene insertion 3e.1, Michael P Matise
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr209*-lacZ)3e.1deltaGliMtse | MGI:7327550
Name: transgene insertion 3e.1deltaGli, Michael P Matise
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr209*-lacZ)3e.1deltaTcfMtse | MGI:7327552
Name: transgene insertion 3e.1deltaTcf, Michael P Matise
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr209*-lacZ)3e.2deltaTcfMtse | MGI:7327553
Name: transgene insertion 3e.2deltaTcf, Michael P Matise
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: B6.CC57BR-Pax1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkx2-2/Nkx2-2<+>
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1<+>
Background: involves: CC57BR/MvY
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: involves: CC57BR/MvY
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: involves: C57BL/6 * CC57BR/MvY
Zygosity: hm
Has Mutant Allele: true
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Publication
16814281 | J:114582
First Author: Cassiani-Ingoni R
Year: 2006
Journal: Exp Neurol
Title: Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation.
Volume: 201
Issue: 2
Pages: 349-58
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Publication
18192873 | J:134561
First Author: Hamblet NS
Year: 2008
Journal: Pancreas
Title: The Reg family member INGAP is a marker of endocrine patterning in the embryonic pancreas.
Volume: 36
Issue: 1
Pages: 1-9
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Publication
20020058 | J:155951
First Author: Yang J
Year: 2009
Journal: PLoS One
Title: P21cip-overexpression in the mouse beta cells leads to the improved recovery from streptozotocin-induced diabetes.
Volume: 4
Issue: 12
Pages: e8344
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Publication
21750032 | J:175542
First Author: Anderson KR
Year: 2011
Journal: Development
Title: The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration.
Volume: 138
Issue: 15
Pages: 3213-24
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Publication
23000619 | J:192751
 
First Author: Garay LI
Year: 2012
Journal: Neuroscience
Title: Progesterone down-regulates spinal cord inflammatory mediators and increases myelination in experimental autoimmune encephalomyelitis.
Volume: 226
Pages: 40-50
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Publication
14576336 | J:201714
First Author: Smith SB
Year: 2004
Journal: Mol Endocrinol
Title: Neurogenin3 activates the islet differentiation program while repressing its own expression.
Volume: 18
Issue: 1
Pages: 142-9
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Publication
28397780 | J:252020
 
First Author: Xue M
Year: 2017
Journal: Nat Commun
Title: Computational identification of mutually exclusive transcriptional drivers dysregulating metastatic microRNAs in prostate cancer.
Volume: 8
Pages: 14917
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Publication
32882218 | J:301092
First Author: Mei ZL
Year: 2020
Journal: Exp Cell Res
Title: CSN6 aggravates Ang II-induced cardiomyocyte hypertrophy via inhibiting SIRT2.
Volume: 396
Issue: 1
Pages: 112245
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Genotype
Genotype
Symbol: Pax1/Pax1<+>
Background: involves: C57BL/6 * CC57BR/MvY
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1<+> Etn2/Etn2<+>
Background: involves: C57BL/6 * C57BL/6ByJ * CC57BR/MvY
Zygosity: cx
Has Mutant Allele: true
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GXD Expression
GXD Expression
     
Probe: MGI:5642284
Assay Type: RT-PCR
Annotation Date: 2015-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:5642286
Age: embryonic day 18.5
Specimen Label: Nkx2.2 KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5642285
Assay Type: RT-PCR
Annotation Date: 2015-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:5642287
Age: embryonic day 18.5
Specimen Label: Nkx2.2 KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6433769
Assay Type: RT-PCR
Annotation Date: 2020-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750321
Stage: TS21
Assay Id: MGI:6433810
Age: embryonic day 13.5
Image: S1
Specimen Label: e13.5 Nkx2.2 KO
Detected: true
Specimen Num: 2
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