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Search results 1501 to 1600 out of 6869 for Nodal

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Type Details Score
GXD Expression
Probe: MGI:4885902
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945245
Age: postnatal day 7
Image: g00724 P7
Note: Expression was region specific and scattered.
Specimen Label: g00724 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4885902
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945245
Age: embryonic day 15.5
Image: g00724 E15.5
Specimen Label: g00724 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4885902
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945245
Age: embryonic day 15.5
Image: g00724 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00724 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4885902
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945245
Age: postnatal day 7
Image: g00724 P7
Note: Expression was region specific and scattered.
Specimen Label: g00724 P7
Detected: true
Specimen Num: 3
Genotype
Symbol: Nodal/Nodal<+> Tg(Rr443-Lefty1,-lacZ)36Hmd/?
Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6N) or (involves: 129S1/Sv * 129T2/SvEms * 129X1/SvJ)
Zygosity: cx
Has Mutant Allele: true
Allele
Name: nodal growth differentiation factor; targeted mutation 1, Michael R Kuehn
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph, Reporter
Allele
Name: nodal growth differentiation factor; targeted mutation 1, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: nodal growth differentiation factor; targeted mutation 1.2, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Modified regulatory region, Null/knockout
Allele
Name: nodal growth differentiation factor; targeted mutation 1.1, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Modified regulatory region, Null/knockout
Allele
Name: nodal growth differentiation factor; targeted mutation 2, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Modified regulatory region, Null/knockout
Allele
Name: nodal growth differentiation factor; targeted mutation 3, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Modified regulatory region, Null/knockout
Allele
Name: nodal growth differentiation factor; targeted mutation 1, Hiroshi Hamada
Allele Type: Targeted
Attribute String: Hypomorph, Modified regulatory region
Allele
Name: nodal growth differentiation factor; targeted mutation 4, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Hypomorph, Modified regulatory region
Allele
Name: nodal growth differentiation factor; targeted mutation 5, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: nodal growth differentiation factor; targeted mutation 6, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: nodal growth differentiation factor; targeted mutation 1.1, Hiroshi Hamada
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: nodal growth differentiation factor; targeted mutation 1, Daniel B Constam
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: nodal growth differentiation factor; targeted mutation 1.1, Daniel B Constam
Allele Type: Targeted
Attribute String: Inserted expressed sequence
Allele
Name: nodal growth differentiation factor; targeted mutation 2, Michael R Kuehn
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele  
Name: nodal modulator 1; gene trap D158D02, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap Ex612, BayGenomics
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap OST122914, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: nodal modulator 1; gene trap OST304485, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap OST329036, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: nodal modulator 1; gene trap EUCG0005d03, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Allele
Name: nodal growth differentiation factor; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: nodal growth differentiation factor; targeted mutation 1.1, Yumiko Saga
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: nodal growth differentiation factor; targeted mutation 2, Hiroshi Hamada
Allele Type: Targeted
Attribute String: Reporter
Allele
Name: nodal growth differentiation factor; targeted mutation 2.1, Hiroshi Hamada
Allele Type: Targeted
Attribute String: Not Specified
Allele
Name: nodal modulator 1; endonuclease-mediated mutation 1, Manuel Sanchez-Martin
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready
Allele
Name: nodal growth differentiation factor; targeted mutation 5.1, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: nodal growth differentiation factor; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele
Name: nodal modulator 1; endonuclease-mediated mutation 5, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: nodal modulator 1; endonuclease-mediated mutation 1, Institute of Molecular Genetics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: nodal growth differentiation factor; targeted mutation 3.1, Hiroshi Hamada
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: nodal growth differentiation factor; targeted mutation 3.2, Hiroshi Hamada
Allele Type: Targeted
Attribute String: Not Specified
MP Term
Allele
Name: kinesin family member 3A; targeted mutation 1, Nobutaka Hirokawa
Allele Type: Targeted
Attribute String: Null/knockout
CL Term
GO Term
GXD Expression  
Probe: MGI:5316990
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-05-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5316996
Age: embryonic day 7.75
Note: Staining is present in embryonic node cilia in the nodal pit and crown.
Specimen Label: 1E
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1895541
Assay Type: RNA in situ
Annotation Date: 2018-05-17
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:6156813
Age: embryonic day 7.75-8.0
Image: 4Be
Note: Expression was severely down-regulated in the node and nodal cilia in the mutant.
Specimen Label: 4Be
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:1895541
Assay Type: RNA in situ
Annotation Date: 2018-05-17
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:6156813
Age: embryonic day 7.75-8.0
Image: 4Be'
Note: Expression was severely down-regulated in the node and nodal cilia in the mutant.
Specimen Label: 4Be'
Detected: true
Specimen Num: 10
GXD Expression
Probe: MGI:1901450
Assay Type: RNA in situ
Annotation Date: 2018-05-17
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:6156834
Age: embryonic day 7.75-8.0
Image: 4Bf
Note: Expression was severely down-regulated in the node and nodal cilia in the mutant.
Specimen Label: 4Bf
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1908788
Assay Type: RNA in situ
Annotation Date: 2018-05-17
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:6156840
Age: embryonic day 7.75-8.0
Image: 4Bg
Note: Expression was severely down-regulated in the node and nodal cilia in the mutant.
Specimen Label: 4Bg
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6156527
Assay Type: RNA in situ
Annotation Date: 2018-05-17
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:6156860
Age: embryonic day 7.75-8.0
Image: 4Bh
Note: Expression was severely down-regulated in the node and nodal cilia in the mutant.
Specimen Label: 4Bh
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6256461
Assay Type: Immunohistochemistry
Annotation Date: 2018-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:6256466
Age: embryonic day 8.0
Image: 2E lower
Note: Reduced number of nodal cilia and surface area than that of wild-type.
Specimen Label: 2E lower
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6414925
Assay Type: RNA in situ
Annotation Date: 2020-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Patchy
Stage: TS12
Assay Id: MGI:6415017
Age: embryonic day 8.0
Image: 5b
Note: Same patchy expression we detected in the embryos lacking nodal flow (summarized in Table 3).
Specimen Label: 5b
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: A hypomorphic mutation of Nodal (D600) has no phenotypic consequence in the heterozygote.
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Embryos heterozygous for a null allele of Nodal have no phenotype.
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Embryos homozygous for the D600 allele of Nodal exhibit a spectrum of defects, including no phenotype.
Specimen Label: 1F
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Decreasing Nodal function on the Zic2 Ku background leads to moderate or severe truncation.
Specimen Label: 1I
Specimen Num: 9
GXD Expression  
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: A hypomorphic mutation of Nodal (D600) has no phenotypic consequence in the heterozygote.
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Embryos heterozygous for a null allele of Nodal have no phenotype.
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Embryos homozygous for the D600 allele of Nodal exhibit a spectrum of defects, including no phenotype.
Specimen Label: 1F
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Decreasing Nodal function on the Zic2 Ku background leads to moderate or severe truncation.
Specimen Label: 1I
Specimen Num: 9
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160729
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:6150455
Age: embryonic day 6.5
Image: 1A
Note: Enriched expression was found in the gastrulating nodal tissue and primitive streak.
Specimen Label: 1A
Detected: true
Specimen Num: 1
Genotype
Symbol: Nodal/Nodal
Background: either: (involves: 129S1/Sv * FVB/N) or (involves: 129S1/Sv * C57BL/6J * FVB/N)
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Nodal/Nodal
Background: involves: 129S1/Sv
Zygosity: ht
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GO Term
CL Term
CL Term
MP Term
Allele
Name: transgene insertion 3, Hiroshi Hamada
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 5, Hiroshi Hamada
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 82, Hiroshi Hamada
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: transgenic, mutant stock
Allele
Name: transgene insertion 34, Hiroshi Hamada
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Allele
Name: transgene insertion 1, Hiroshi Hamada
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: coisogenic, mutant strain
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant stock
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant stock
Strain
Attribute String: mutant stock, targeted mutation
Allele  
Name: nodal growth differentiation factor; gene trap P082E01, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap G020G07, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap G060C07, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P031D01, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap IST12883D4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap G024G11, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap W202B05, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap G020F07, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap G056G06, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap Q008F03, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P031C10, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P033A11, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P031E08, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P031E04, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P031D05, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P031A06, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P033H10, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P032E11, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P033E04, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P033G02, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P033F04, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P032G01, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: nodal growth differentiation factor; gene trap P032G07, German Gene Trap Consortium
Allele Type: Gene trapped