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Search results 1501 to 1600 out of 5471 for Tyr

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0.017s

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Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Ins2/Ins2
Background: C.B6N-Ins2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2<+>
Background: C.B6N-Ins2
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2<+>
Background: involves: C57BL/6NSlc
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fkrp/Fkrp Sox1/Sox1<+>
Background: involves: C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fance/Fance
Background: FVB/N-Fance/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arb2a/Arb2a<+>
Background: involves: FVB/N
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arb2a/Arb2a
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
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Protein
Q9DBC0
Organism: Mus musculus/domesticus
Length: 667  
Fragment?: false
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Protein
B9EJ24
Organism: Mus musculus/domesticus
Length: 667  
Fragment?: false
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Protein
A4FUU9
Organism: Mus musculus/domesticus
Length: 503  
Fragment?: true
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Protein
S4R1U9
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
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Publication
30270044 | -
First Author: Sreelatha A
Year: 2018
Journal: Cell
Title: Protein AMPylation by an Evolutionarily Conserved Pseudokinase.
Volume: 175
Issue: 3
Pages: 809-821.e19
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Publication
24751718 | -
First Author: Han SJ
Year: 2014
Journal: PLoS One
Title: Characterization of mammalian selenoprotein o: a redox-active mitochondrial protein.
Volume: 9
Issue: 4
Pages: e95518
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Publication
21326359 | -
First Author: Barnett C
Year: 2011
Journal: Biochem Cell Biol
Title: WSTF does it all: a multifunctional protein in transcription, repair, and replication.
Volume: 89
Issue: 1
Pages: 12-23
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Publication
15840573 | -
First Author: Choowongkomon K
Year: 2005
Journal: J Biol Chem
Title: A structural model for the membrane-bound form of the juxtamembrane domain of the epidermal growth factor receptor.
Volume: 280
Issue: 25
Pages: 24043-52
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Publication
15173825 | -
First Author: Hubbard SR
Year: 2004
Journal: Nat Rev Mol Cell Biol
Title: Juxtamembrane autoinhibition in receptor tyrosine kinases.
Volume: 5
Issue: 6
Pages: 464-71
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Publication
17912370 | -
First Author: Louie GV
Year: 2007
Journal: PLoS One
Title: Structure and reaction mechanism of basil eugenol synthase.
Volume: 2
Issue: 10
Pages: e993
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Protein Domain
IPR017200 | PqqE-like
Type: Family
Description: This entry represents coenzyme PQQ biosynthesis protein E, which is a prototypical peptide-cyclising radical SAM enzyme. It links a Tyr to a Glu as the first step in the biosynthesis of pyrrolo-quinoline-quinone (coenzyme PQQ) from the precursor peptide PqqA. PQQ is required for some glucose dehydrogenases and alcohol dehydrogenases.This entry also includes some other radical SAM enzymes, such as tungsten-containing aldehyde ferredoxin oxidoreductase cofactor-modifying protein, adoMet-dependent heme synthase []and Fe-coproporphyrin III synthase [].
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Protein Domain
IPR044912 | Egfr_JX_dom
Type: Homologous_superfamily
Description: Receptor tyrosine kinases (RTKs) are transmembrane receptors thathave intrinsic, cytoplasmic tyrosine kinase activity. Juxtamembrane regions in RTKs have been shown to play important regulatory functions. Their kinase activity is generally autoinhibited by its JX domain in the absence of ligand-stimulated tyrosine phosphorylation, due to the inhibitory Tyr phosphorylation sites found in the JX domain []. This superfamily represents the JX domain of the EGF receptor [].
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Protein Domain
IPR003846 | SelO
Type: Family
Description: SelO and its homologues are widespread among most eukaryotic taxa, and are also common in many major bacterial taxa. SelO is a conserved pseudokinase that transfers AMP from ATP to Ser, Thr, and Tyr residues on protein substrates (AMPylation). It contains a protein kinase fold with ATP flipped in the active site []. In eukaryotes, it is a mitochondrial protein that may be involved in redox biology [].
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Protein Domain
IPR037375 | BAZ1B_Bromo
Type: Domain
Description: BAZ1B (also known as Williams-Beuren syndrome transcription factor, WSTF) is a component of the WICH complex (WSTF-ISWI ATP-dependent chromatin-remodelling complex). It has intrinsic tyrosine kinase activity by means of a domain that shares no sequence homology to any known kinase fold. It has been shown to phosphorylate Tyr 142 of H2A []. It is involved in chromatin assembly, RNA polymerase I and III gene regulation, vitamin D metabolism, and DNA repair [].
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Protein Domain
IPR045312 | PCBER-like
Type: Domain
Description: Phenylcoumaran benzylic ether reductases and pinoresinol-lariciresinol reductases are NADPH-dependent aromatic alcohol reductases, and are atypical members of the SDR (short-chain dehydrogenase/reductase) family. Other proteins containing this domain are identified as eugenol synthase []. These proteins contain an N-terminal characteristic of NAD(P)-binding proteins and a small C-terminal domain presumed to be involved in substrate binding, but they do not have the conserved active site Tyr residue typically found in SDRs [].
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Publication
11850825 | J:74729
First Author: Wilhelmsen K
Year: 2002
Journal: Oncogene
Title: C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus.
Volume: 21
Issue: 7
Pages: 1079-89
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Publication
15286659 | J:116246
First Author: Lee C
Year: 2004
Journal: Nature
Title: Structural basis for inhibition of the replication licensing factor Cdt1 by geminin.
Volume: 430
Issue: 7002
Pages: 913-7
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Publication
20107910 | J:184817
First Author: Qi S
Year: 2011
Journal: Mol Biol Rep
Title: A mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) is highly expressed in retina that exhibits a large area of intrinsic disorder.
Volume: 38
Issue: 5
Pages: 2869-77
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Publication
9538257 | J:47241
First Author: Hori S
Year: 1998
Journal: J Biochem
Title: Purification and characterization of myonase from X-chromosome linked muscular dystrophic mouse skeletal muscle.
Volume: 123
Issue: 4
Pages: 650-8
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Publication
18669639 | J:142316
First Author: Zhang YY
Year: 2008
Journal: J Biol Chem
Title: Enzymatic activity and substrate specificity of mitogen-activated protein kinase p38alpha in different phosphorylation states.
Volume: 283
Issue: 39
Pages: 26591-601
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Publication
12604616 | J:82957
First Author: Kovalenko D
Year: 2003
Journal: J Biol Chem
Title: Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.
Volume: 278
Issue: 16
Pages: 14087-91
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Publication
9891090 | J:52243
First Author: Tournier C
Year: 1999
Journal: Mol Cell Biol
Title: The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases.
Volume: 19
Issue: 2
Pages: 1569-81
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Publication
12624093 | J:83279
First Author: Kishimoto H
Year: 2003
Journal: J Biol Chem
Title: Different properties of SEK1 and MKK7 in dual phosphorylation of stress-induced activated protein kinase SAPK/JNK in embryonic stem cells.
Volume: 278
Issue: 19
Pages: 16595-601
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Publication
16911521 | J:302450
First Author: Su D
Year: 2006
Journal: FEBS J
Title: Three mammalian cytochromes b561 are ascorbate-dependent ferrireductases.
Volume: 273
Issue: 16
Pages: 3722-34
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Publication
17123648 | J:118530
First Author: Peng J
Year: 2006
Journal: Biochim Biophys Acta
Title: Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain.
Volume: 1759
Issue: 11-12
Pages: 562-72
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Publication
12594516 | J:82334
First Author: Bates SH
Year: 2003
Journal: Nature
Title: STAT3 signalling is required for leptin regulation of energy balance but not reproduction.
Volume: 421
Issue: 6925
Pages: 856-9
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Publication
11123925 | J:292526
First Author: Sbrissa D
Year: 2000
Journal: Biochemistry
Title: PIKfyve lipid kinase is a protein kinase: downregulation of 5'-phosphoinositide product formation by autophosphorylation.
Volume: 39
Issue: 51
Pages: 15980-9
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Publication
9867848 | J:51814
First Author: Huber M
Year: 1999
Journal: J Biol Chem
Title: The carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cells.
Volume: 274
Issue: 1
Pages: 335-44
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Publication
11574907 | J:72440
First Author: Newton JM
Year: 2001
Journal: Am J Hum Genet
Title: Mutations in the human orthologue of the mouse underwhite gene (uw) underlie a new form of oculocutaneous albinism, OCA4.
Volume: 69
Issue: 5
Pages: 981-8
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Publication
9452421 | J:45715
First Author: Wang J
Year: 1998
Journal: J Biol Chem
Title: Insulin-like growth factor-I receptor and insulin receptor association with a Src homology-2 domain-containing putative adapter.
Volume: 273
Issue: 6
Pages: 3136-9
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Publication
18544649 | J:136305
First Author: Guillermet-Guibert J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.
Volume: 105
Issue: 24
Pages: 8292-7
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Publication
23506116 | J:214894
First Author: Fuchigami T
Year: 2013
Journal: Genes Cells
Title: Dab1-mediated colocalization of multi-adaptor protein CIN85 with Reelin receptors, ApoER2 and VLDLR, in neurons.
Volume: 18
Issue: 5
Pages: 410-24
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Publication
12930721 | J:86672
First Author: Lundwall A
Year: 2003
Journal: Biol Reprod
Title: Molecular cloning of complementary DNA encoding mouse seminal vesicle-secreted protein SVS I and demonstration of homology with copper amine oxidases.
Volume: 69
Issue: 6
Pages: 1923-30
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Publication
11907037 | J:76851
First Author: Sun Y
Year: 2002
Journal: J Biol Chem
Title: Characterization and expression of L-amino acid oxidase of mouse milk.
Volume: 277
Issue: 21
Pages: 19080-6
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Publication
11111077 | J:66553
First Author: Tansey TR
Year: 2000
Journal: Biochim Biophys Acta
Title: Structure and regulation of mammalian squalene synthase.
Volume: 1529
Issue: 1-3
Pages: 49-62
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Publication
20739468 | J:171565
First Author: Trantow CM
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Microarray analysis of iris gene expression in mice with mutations influencing pigmentation.
Volume: 52
Issue: 1
Pages: 237-48
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Publication
15060160 | J:89896
First Author: Guyonneau L
Year: 2004
Journal: Mol Cell Biol
Title: Melanocytes and pigmentation are affected in dopachrome tautomerase knockout mice.
Volume: 24
Issue: 8
Pages: 3396-403
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Publication
16400036 | J:104432
First Author: Deeb RS
Year: 2006
Journal: Am J Pathol
Title: Inducible nitric oxide synthase mediates prostaglandin h2 synthase nitration and suppresses eicosanoid production.
Volume: 168
Issue: 1
Pages: 349-62
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Publication
25143441 | J:267164
First Author: Patton DT
Year: 2014
Journal: J Immunol
Title: The survival and differentiation of pro-B and pre-B cells in the bone marrow is dependent on IL-7Rα Tyr449.
Volume: 193
Issue: 7
Pages: 3446-55
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Publication
34819582 | J:327809
First Author: Manek R
Year: 2021
Journal: Sci Rep
Title: Blood phenylalanine reduction reverses gene expression changes observed in a mouse model of phenylketonuria.
Volume: 11
Issue: 1
Pages: 22886
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Publication
25432929 | J:221979
First Author: Sonoshita M
Year: 2015
Journal: Cancer Discov
Title: Promotion of colorectal cancer invasion and metastasis through activation of NOTCH-DAB1-ABL-RHOGEF protein TRIO.
Volume: 5
Issue: 2
Pages: 198-211
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Publication
17998387 | J:128517
First Author: Alcázar I
Year: 2007
Journal: J Exp Med
Title: Phosphoinositide 3-kinase gamma participates in T cell receptor-induced T cell activation.
Volume: 204
Issue: 12
Pages: 2977-87
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Publication
12923053 | J:84894
First Author: Kim S
Year: 2003
Journal: Genes Dev
Title: Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation.
Volume: 17
Issue: 16
Pages: 1979-91
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Publication
24107965 | J:202754
First Author: Kokkinaki M
Year: 2013
Journal: J Neurosci
Title: Klotho regulates retinal pigment epithelial functions and protects against oxidative stress.
Volume: 33
Issue: 41
Pages: 16346-59
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Publication
18292512 | J:131542
First Author: Owaki T
Year: 2008
Journal: J Immunol
Title: STAT3 is indispensable to IL-27-mediated cell proliferation but not to IL-27-induced Th1 differentiation and suppression of proinflammatory cytokine production.
Volume: 180
Issue: 5
Pages: 2903-11
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Publication
27076121 | J:234800
First Author: Triaca V
Year: 2016
Journal: Aging Cell
Title: NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease.
Volume: 15
Issue: 4
Pages: 661-72
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Publication
29531172 | J:261432
First Author: Veleeparambil M
Year: 2018
Journal: J Immunol
Title: Constitutively Bound EGFR-Mediated Tyrosine Phosphorylation of TLR9 Is Required for Its Ability To Signal.
Volume: 200
Issue: 8
Pages: 2809-2818
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Publication
19834457 | J:155360
First Author: Taniguchi S
Year: 2009
Journal: EMBO J
Title: Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour.
Volume: 28
Issue: 23
Pages: 3717-29
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Publication
10601245 | J:125134
First Author: Krauss K
Year: 1999
Journal: J Biol Chem
Title: Integrin leukocyte function-associated antigen-1-mediated cell binding can be activated by clustering of membrane rafts.
Volume: 274
Issue: 52
Pages: 36921-7
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Publication
15816000 | J:97781
First Author: Baba T
Year: 2005
Journal: Eur J Immunol
Title: Dual regulation of BCR-mediated growth inhibition signaling by CD72.
Volume: 35
Issue: 5
Pages: 1634-42
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Publication
20371618 | J:162341
First Author: Kiyota T
Year: 2010
Journal: FASEB J
Title: CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice.
Volume: 24
Issue: 8
Pages: 3093-102
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Publication
19934005 | J:164159
First Author: Lloyd DJ
Year: 2010
Journal: Diabetes
Title: A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice.
Volume: 59
Issue: 2
Pages: 460-70
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Publication
25151118 | J:220104
 
First Author: Matté A
Year: 2014
Journal: Free Radic Biol Med
Title: The novel role of peroxiredoxin-2 in red cell membrane protein homeostasis and senescence.
Volume: 76
Pages: 80-8
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Publication
25128699 | J:217773
 
First Author: Mota SI
Year: 2014
Journal: Exp Neurol
Title: Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway.
Volume: 261
Pages: 698-709
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Publication
16452504 | J:105047
First Author: Jain S
Year: 2006
Journal: Genes Dev
Title: Critical and distinct roles for key RET tyrosine docking sites in renal development.
Volume: 20
Issue: 3
Pages: 321-33
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Publication
31562697 | J:284200
First Author: Flesher JL
Year: 2020
Journal: Pigment Cell Melanoma Res
Title: Delineating the role of MITF isoforms in pigmentation and tissue homeostasis.
Volume: 33
Issue: 2
Pages: 279-292
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Publication
22885232 | J:192490
 
First Author: Olausson P
Year: 2012
Journal: Neuroscience
Title: The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity.
Volume: 225
Pages: 1-8
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Publication
33790381 | J:305392
First Author: Singh K
Year: 2021
Journal: Sci Rep
Title: CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria.
Volume: 11
Issue: 1
Pages: 7254
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Publication
19029245 | J:145554
First Author: Van Kanegan MJ
Year: 2009
Journal: Mol Cell Biol
Title: The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation.
Volume: 29
Issue: 3
Pages: 662-74
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Publication
22084075 | J:180398
First Author: Means CK
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria.
Volume: 108
Issue: 48
Pages: E1227-35
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Publication
9154917 | J:40210
First Author: Rao PV
Year: 1997
Journal: Biochemistry
Title: Guinea pig and bovine zeta-crystallins have distinct functional characteristics highlighting replacements in otherwise similar structures.
Volume: 36
Issue: 18
Pages: 5353-62
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Publication
11390389 | J:175114
First Author: Sun J
Year: 2001
Journal: J Biol Chem
Title: c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1.
Volume: 276
Issue: 31
Pages: 28984-90
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Publication
26680585 | J:230032
First Author: Muthusamy BP
Year: 2015
Journal: PLoS Biol
Title: ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.
Volume: 13
Issue: 12
Pages: e1002325
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Publication
17956988 | J:248226
First Author: Lahm A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases.
Volume: 104
Issue: 44
Pages: 17335-40
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Publication
21223507 | J:200502
First Author: Igarashi J
Year: 2011
Journal: FEBS J
Title: Autophosphorylation of heme-regulated eukaryotic initiation factor 2α kinase and the role of the modification in catalysis.
Volume: 278
Issue: 6
Pages: 918-28
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Publication
18235994 | J:343403
First Author: Katane M
Year: 2008
Journal: Amino Acids
Title: Hyperactive mutants of mouse D-aspartate oxidase: mutagenesis of the active site residue serine 308.
Volume: 35
Issue: 1
Pages: 75-82
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Publication
2679557 | J:10069
First Author: Giri PR
Year: 1989
Journal: Biochem Biophys Res Commun
Title: Cloning and comparative mapping of a human class III (chi) alcohol dehydrogenase cDNA.
Volume: 164
Issue: 1
Pages: 453-60
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Publication
1409444 | J:2136
 
First Author: Shibahara S
Year: 1992
Journal: Pigment Cell Res
Title: Identification of mutations in the pigment cell-specific gene located at the brown locus in mouse.
Volume: Suppl 2
Pages: 90-5
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Publication
8288246 | J:15605
First Author: Koch-Nolte F
Year: 1993
Journal: Genomics
Title: Assignment of the human RT6 gene to 11q13 by PCR screening of somatic cell hybrids and in situ hybridization.
Volume: 18
Issue: 2
Pages: 404-6
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Publication
7513208 | J:17895
First Author: Tsujimura T
Year: 1994
Journal: Blood
Title: Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation.
Volume: 83
Issue: 9
Pages: 2619-26
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Publication
7528746 | J:22213
First Author: Haynes PA
Year: 1994
Journal: J Biol Chem
Title: The rat hepatic lectin 1 subunit of the rat asialoglycoprotein receptor is a phosphoprotein and contains phosphotyrosine.
Volume: 269
Issue: 52
Pages: 33146-51
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Publication
7703510 | J:23058
First Author: Ono M
Year: 1994
Journal: DNA Seq
Title: Molecular cloning of cDNA encoding the precursor for hamster hypothalamic growth hormone-releasing factor.
Volume: 5
Issue: 2
Pages: 93-102
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Publication
7559413 | J:29052
First Author: Arora KK
Year: 1995
Journal: J Biol Chem
Title: Effects of second intracellular loop mutations on signal transduction and internalization of the gonadotropin-releasing hormone receptor.
Volume: 270
Issue: 39
Pages: 22820-6
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Publication
7499190 | J:29770
First Author: Winston BW
Year: 1995
Journal: J Biol Chem
Title: Preferential involvement of MEK1 in the tumor necrosis factor-alpha-induced activation of p42mapk/erk2 in mouse macrophages.
Volume: 270
Issue: 46
Pages: 27391-4
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Publication
8626452 | J:31952
First Author: Chu Y
Year: 1996
Journal: J Biol Chem
Title: The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation.
Volume: 271
Issue: 11
Pages: 6497-501
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Publication
8631931 | J:31428
First Author: Moriyama Y
Year: 1996
Journal: J Biol Chem
Title: Role of aspartic acid 814 in the function and expression of c-kit receptor tyrosine kinase.
Volume: 271
Issue: 7
Pages: 3347-50
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Publication
9201930 | J:41172
First Author: Rousselot P
Year: 1997
Journal: Biochemistry
Title: Specific photoaffinity labeling of Tyr-49 on the light chain in the steroid-combining site of a mouse monoclonal anti-estradiol antibody using two epimeric 6alpha- and 6beta-(5-azido-2-nitrobenzoyl)amidoestradiol photoreagents.
Volume: 36
Issue: 25
Pages: 7860-8
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Publication
9299234 | J:43183
First Author: Kimura SH
Year: 1997
Journal: Genomics
Title: Structure, expression, and chromosomal localization of human GAK.
Volume: 44
Issue: 2
Pages: 179-87
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Publication
9893986 | J:52293
First Author: Buist A
Year: 1999
Journal: Biochemistry
Title: Restoration of potent protein-tyrosine phosphatase activity into the membrane-distal domain of receptor protein-tyrosine phosphatase alpha.
Volume: 38
Issue: 3
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