| Type |
Details |
Score |
| Strain |
| Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schonbrunn A |
| Year: |
1978 |
| Journal: |
J Biol Chem |
| Title: |
Characterization of functional receptors for somatostatin in rat pituitary cells in culture. |
| Volume: |
253 |
| Issue: |
18 |
| Pages: |
6473-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jahed A |
| Year: |
2005 |
| Journal: |
Auton Neurosci |
| Title: |
The influences of p75 neurotrophin receptor and brain-derived neurotrophic factor in the sympathetic innervation of target tissues during murine postnatal development. |
| Volume: |
118 |
| Issue: |
1-2 |
| Pages: |
32-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Erck C |
| Year: |
2005 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A vital role of tubulin-tyrosine-ligase for neuronal organization. |
| Volume: |
102 |
| Issue: |
22 |
| Pages: |
7853-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Samraj AN |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A red meat-derived glycan promotes inflammation and cancer progression. |
| Volume: |
112 |
| Issue: |
2 |
| Pages: |
542-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chan MF |
| Year: |
2013 |
| Journal: |
J Cell Sci |
| Title: |
Protective effects of matrix metalloproteinase-12 following corneal injury. |
| Volume: |
126 |
| Issue: |
Pt 17 |
| Pages: |
3948-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tamura A |
| Year: |
1996 |
| Journal: |
Cell Immunol |
| Title: |
Inhibition of apoptosis and augmentation of lymphoproliferation in bcl-2 transgenic Fas/Fas ligand-defective mice. |
| Volume: |
168 |
| Issue: |
2 |
| Pages: |
220-8 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
CarBa is the A subunit of 2-aminobiphenyl-2,3-diol 1,2-dioxygenase, which catalyzes the oxidization and subsequent ring-opening of 2-aminophenyl-2,3-diol. It is a key enzyme in the carbazole degradation pathway isolated from bacterial strains with carbazole degradation ability. The enzyme is a heterotetramer composed of two A and two B subunits. CarB belongs to the class III extradiol dioxygenase family, composed of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon. Although the enzyme was originally isolated as a meta-cleavage enzyme for 2'-aminobiphenyl-2,3-diol involved in carbazole degradation, the enzyme has also shown high specificity for 2,3-dihydroxybiphenyl []. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry represents CbsA, a novel, highly glycosylated, mono-haem cytochrome b558/566 found in Sulfolobus acidocaldarius and several other members of the Sulfolobales, a branch of the Crenarchaeota [, ]. Encoded at the same locus as CbsA are: CbsB, a hydrophobic protein, SoxL, a Rieske iron-sulphur protein, SoxN, a predicted membrane-bound b-type cytochrome b, and OdsN, a protein of unknown function. Transcriptional studies suggest that these proteins may form a complex analogous to the cytochrome bc1 complex. The redox-active subunits of this complex would consist of CbsA, SoxL and SoxN, while CbsB and OdsN would be additional non-redox-active subunits. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cîrciumaru A |
| Year: |
2023 |
| Journal: |
Biomolecules |
| Title: |
Anti-Citrullinated Protein Antibody Reactivity towards Neutrophil-Derived Antigens: Clonal Diversity and Inter-Individual Variation. |
| Volume: |
13 |
| Issue: |
4 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lemmer ER |
| Year: |
2000 |
| Journal: |
Cytogenet Cell Genet |
| Title: |
Genomic structure and chromosome location of the mouse RelA p65 gene (Rela). |
| Volume: |
89 |
| Issue: |
1-2 |
| Pages: |
129-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zawerton A |
| Year: |
2019 |
| Journal: |
Am J Hum Genet |
| Title: |
De Novo SOX4 Variants Cause a Neurodevelopmental Disease Associated with Mild Dysmorphism. |
| Volume: |
104 |
| Issue: |
2 |
| Pages: |
246-259 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Puri V |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Cidea is associated with lipid droplets and insulin sensitivity in humans. |
| Volume: |
105 |
| Issue: |
22 |
| Pages: |
7833-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mumau MD |
| Year: |
2018 |
| Journal: |
J Immunol |
| Title: |
Identification of a Multipotent Progenitor Population in the Spleen That Is Regulated by NR4A1. |
| Volume: |
200 |
| Issue: |
3 |
| Pages: |
1078-1087 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsushima Y |
| Year: |
1983 |
| Journal: |
Jpn J Zootech Sci |
| Title: |
Genetic analysis of mouse tear protein system-1 (Mtp-1) |
| Volume: |
54 |
| Issue: |
4 |
| Pages: |
269-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen CC |
| Year: |
2002 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A role for ASIC3 in the modulation of high-intensity pain stimuli. |
| Volume: |
99 |
| Issue: |
13 |
| Pages: |
8992-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Luque RM |
| Year: |
2007 |
| Journal: |
Endocrinology |
| Title: |
Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using mouse models and a cell line. |
| Volume: |
148 |
| Issue: |
10 |
| Pages: |
4601-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Georgel P |
| Year: |
2005 |
| Journal: |
Infect Immun |
| Title: |
A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria. |
| Volume: |
73 |
| Issue: |
8 |
| Pages: |
4512-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuma A |
| Year: |
2008 |
| Journal: |
Autophagy |
| Title: |
Chromosomal mapping of the GFP-LC3 transgene in GFP-LC3 mice. |
| Volume: |
4 |
| Issue: |
1 |
| Pages: |
61-2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mahavadi S |
| Year: |
2017 |
| Journal: |
PLoS One |
| Title: |
Diabetes-induced oxidative stress mediates upregulation of RhoA/Rho kinase pathway and hypercontractility of gastric smooth muscle. |
| Volume: |
12 |
| Issue: |
7 |
| Pages: |
e0178574 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Antal MC |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant. |
| Volume: |
105 |
| Issue: |
7 |
| Pages: |
2433-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hienola A |
| Year: |
2004 |
| Journal: |
Mol Cell Neurosci |
| Title: |
HB-GAM inhibits proliferation and enhances differentiation of neural stem cells. |
| Volume: |
26 |
| Issue: |
1 |
| Pages: |
75-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hamilton A |
| Year: |
2012 |
| Journal: |
Brain Res |
| Title: |
The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease. |
| Volume: |
1449 |
|
| Pages: |
83-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coutinho A |
| Year: |
1978 |
| Journal: |
Immunogenetics |
| Title: |
Genetic basis for unresponsiveness to lipopolysaccharide in C57BL/10Cr mice. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
17-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Holz A |
| Year: |
2000 |
| Journal: |
J Immunol |
| Title: |
Neither B lymphocytes nor antibodies directed against self antigens of the islets of Langerhans are required for development of virus-induced autoimmune diabetes. |
| Volume: |
165 |
| Issue: |
10 |
| Pages: |
5945-53 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1704
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamak A |
| Year: |
2020 |
| Journal: |
iScience |
| Title: |
Loss of Asb2 Impairs Cardiomyocyte Differentiation and Leads to Congenital Double Outlet Right Ventricle. |
| Volume: |
23 |
| Issue: |
3 |
| Pages: |
100959 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gesteira TF |
| Year: |
2017 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation. |
| Volume: |
58 |
| Issue: |
11 |
| Pages: |
4407-4421 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bernard-Valnet R |
| Year: |
2016 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice. |
| Volume: |
113 |
| Issue: |
39 |
| Pages: |
10956-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suresh A |
| Year: |
2017 |
| Journal: |
Cereb Cortex |
| Title: |
Relationship Between Synaptic AMPAR and Spine Dynamics: Impairments in the FXS Mouse. |
| Volume: |
27 |
| Issue: |
8 |
| Pages: |
4244-4256 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Durkin ME |
| Year: |
1997 |
| Journal: |
FEBS Lett |
| Title: |
Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation. |
| Volume: |
411 |
| Issue: |
2-3 |
| Pages: |
296-300 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Franco A Jr |
| Year: |
1990 |
| Journal: |
Nature |
| Title: |
Calcium entry through stretch-inactivated ion channels in mdx myotubes. |
| Volume: |
344 |
| Issue: |
6267 |
| Pages: |
670-3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pajvani UB |
| Year: |
2005 |
| Journal: |
Nat Med |
| Title: |
Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy. |
| Volume: |
11 |
| Issue: |
7 |
| Pages: |
797-803 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sommermann T |
| Year: |
2020 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis. |
| Volume: |
117 |
| Issue: |
25 |
| Pages: |
14421-14432 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jacks A |
| Year: |
2003 |
| Journal: |
Structure |
| Title: |
Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element. |
| Volume: |
11 |
| Issue: |
7 |
| Pages: |
833-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
DeMattos RB |
| Year: |
2002 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease. |
| Volume: |
99 |
| Issue: |
16 |
| Pages: |
10843-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Noble A |
| Year: |
1998 |
| Journal: |
J Immunol |
| Title: |
Suppression of immune responses by CD8 cells. II. Qa-1 on activated B cells stimulates CD8 cell suppression of T helper 2 responses. |
| Volume: |
160 |
| Issue: |
2 |
| Pages: |
566-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Christensen A |
| Year: |
2019 |
| Journal: |
FASEB J |
| Title: |
APOE genotype affects metabolic and Alzheimer-related outcomes induced by Western diet in female EFAD mice. |
| Volume: |
33 |
| Issue: |
3 |
| Pages: |
4054-4066 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Robinson ML |
| Year: |
1995 |
| Journal: |
Development |
| Title: |
Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice. |
| Volume: |
121 |
| Issue: |
2 |
| Pages: |
505-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Walt A |
| Year: |
2002 |
| Journal: |
J Bacteriol |
| Title: |
The fixA and fixB genes are necessary for anaerobic carnitine reduction in Escherichia coli. |
| Volume: |
184 |
| Issue: |
14 |
| Pages: |
4044-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Weidemann A |
| Year: |
2002 |
| Journal: |
Biochemistry |
| Title: |
A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing. |
| Volume: |
41 |
| Issue: |
8 |
| Pages: |
2825-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Luo Y |
| Year: |
2015 |
| Journal: |
J Pathol |
| Title: |
A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells. |
| Volume: |
236 |
| Issue: |
3 |
| Pages: |
384-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Y |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
A role for protein inhibitor of activated STAT1 (PIAS1) in lipogenic regulation through SUMOylation-independent suppression of liver X receptors. |
| Volume: |
287 |
| Issue: |
45 |
| Pages: |
37973-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Murakami DM |
| Year: |
2002 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Evidence for vestibular regulation of autonomic functions in a mouse genetic model. |
| Volume: |
99 |
| Issue: |
26 |
| Pages: |
17078-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kallies A |
| Year: |
2009 |
| Journal: |
Immunity |
| Title: |
Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses. |
| Volume: |
31 |
| Issue: |
2 |
| Pages: |
283-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Roy A |
| Year: |
2014 |
| Journal: |
Cereb Cortex |
| Title: |
Lhx2 regulates the development of the forebrain hem system. |
| Volume: |
24 |
| Issue: |
5 |
| Pages: |
1361-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kroner A |
| Year: |
2009 |
| Journal: |
PLoS One |
| Title: |
PD-1 regulates neural damage in oligodendroglia-induced inflammation. |
| Volume: |
4 |
| Issue: |
2 |
| Pages: |
e4405 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chanda B |
| Year: |
2013 |
| Journal: |
Cell |
| Title: |
Retinoic acid signaling is essential for embryonic hematopoietic stem cell development. |
| Volume: |
155 |
| Issue: |
1 |
| Pages: |
215-27 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morohoshi A |
| Year: |
2019 |
| Journal: |
Dev Biol |
| Title: |
The ubiquitin ligase subunit β-TrCP in Sertoli cells is essential for spermatogenesis in mice. |
| Volume: |
445 |
| Issue: |
2 |
| Pages: |
178-188 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kokkotou E |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Melanin-concentrating hormone as a mediator of intestinal inflammation. |
| Volume: |
105 |
| Issue: |
30 |
| Pages: |
10613-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leduc MS |
| Year: |
2016 |
| Journal: |
Am J Med Genet A |
| Title: |
CRIPT exonic deletion and a novel missense mutation in a female with short stature, dysmorphic features, microcephaly, and pigmentary abnormalities. |
| Volume: |
170 |
| Issue: |
8 |
| Pages: |
2206-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ongherth A |
| Year: |
2015 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
p63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts. |
| Volume: |
88 |
|
| Pages: |
39-54 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Nucleoside diphosphate-linked moiety X motif 19 (NUDT19 or RP2p) is a coenzyme A diphosphatase. It hydrolases CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters. Medium and long-chain fatty-acyl-CoA esters are the primary substrates. The protein contains a nudix hydrolase domain, a CoA-binding domain and a peroxisomal targeting signal at the C terminus, and activity in the mouse kidney is restricted to peroxisomes. The enzyme is active at pH 9 or above and requires Mn2+or Mg2+ions [].There are numerous uncharacterized bacterial and archaeal homologues. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schwartz C |
| Year: |
2015 |
| Journal: |
Blood |
| Title: |
Eosinophil-specific deletion of IκBα in mice reveals a critical role of NF-κB-induced Bcl-xL for inhibition of apoptosis. |
| Volume: |
125 |
| Issue: |
25 |
| Pages: |
3896-904 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mencacci A |
| Year: |
2000 |
| Journal: |
Infect Immun |
| Title: |
Interleukin 18 restores defective Th1 immunity to Candida albicans in caspase 1-deficient mice. |
| Volume: |
68 |
| Issue: |
9 |
| Pages: |
5126-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Milanesi A |
| Year: |
2016 |
| Journal: |
Endocrinology |
| Title: |
Thyroid Hormone Receptor α Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury. |
| Volume: |
157 |
| Issue: |
1 |
| Pages: |
4-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reynolds AE |
| Year: |
2015 |
| Journal: |
J Immunol |
| Title: |
Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. |
| Volume: |
194 |
| Issue: |
1 |
| Pages: |
231-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nicholson-Weller A |
| Year: |
1999 |
| Journal: |
Curr Opin Immunol |
| Title: |
C1q-binding proteins and C1q receptors. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
42-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jais A |
| Year: |
2016 |
| Journal: |
Cell |
| Title: |
Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity. |
| Volume: |
165 |
| Issue: |
4 |
| Pages: |
882-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zembrzycki A |
| Year: |
2007 |
| Journal: |
Neural Dev |
| Title: |
Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain. |
| Volume: |
2 |
|
| Pages: |
8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Seeler JS |
| Year: |
1998 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment. |
| Volume: |
95 |
| Issue: |
13 |
| Pages: |
7316-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muñoz-Bravo JL |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity. |
| Volume: |
11 |
| Issue: |
10 |
| Pages: |
e0164714 |
|
•
•
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•
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