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Search results 1601 to 1700 out of 2733 for C6

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Type Details Score
Publication
6436243 | J:72469
First Author: Farrell SO
Year: 1984
Journal: J Biol Chem
Title: Properties of purified carnitine acyltransferases of mouse liver peroxisomes.
Volume: 259
Issue: 21
Pages: 13089-95
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Publication
8111631 | J:34988
First Author: Mellon SH
Year: 1993
Journal: Brain Res
Title: Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain.
Volume: 629
Issue: 2
Pages: 283-92
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Publication
19519661 | J:282605
First Author: Machová E
Year: 2009
Journal: J Neurochem
Title: Detection of choline transporter-like 1 protein CTL1 in neuroblastoma x glioma cells and in the CNS, and its role in choline uptake.
Volume: 110
Issue: 4
Pages: 1297-309
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Publication
23876310 | J:334005
First Author: Oya M
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Vesicular nucleotide transporter is involved in ATP storage of secretory lysosomes in astrocytes.
Volume: 438
Issue: 1
Pages: 145-51
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Publication
36002575 | J:335673
First Author: Stafford CA
Year: 2022
Journal: Nature
Title: Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
Volume: 609
Issue: 7927
Pages: 590-596
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Publication
11146111 | J:67108
First Author: Tanaka M
Year: 2000
Journal: Brain Res Mol Brain Res
Title: Promoter analysis and characteristics of the 5'-untranslated region of the mouse glial cell line-derived neurotrophic factor gene.
Volume: 85
Issue: 1-2
Pages: 91-102
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Publication
11684090 | J:72404
First Author: Hur J
Year: 2001
Journal: FEBS Lett
Title: Induction of caspase-11 by inflammatory stimuli in rat astrocytes: lipopolysaccharide induction through p38 mitogen-activated protein kinase pathway.
Volume: 507
Issue: 2
Pages: 157-62
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Publication
11785964 | J:73928
First Author: Satoh K
Year: 2002
Journal: Biochem Biophys Res Commun
Title: A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by beta-amyloid.
Volume: 290
Issue: 2
Pages: 756-62
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Publication
10712606 | J:61124
First Author: Faraonio R
Year: 2000
Journal: Eur J Biochem
Title: Characterization of cis-acting elements in the promoter of the mouse metallothionein-3 gene. Activation of gene expression during neuronal differentiation of P19 embryonal carcinoma cells.
Volume: 267
Issue: 6
Pages: 1743-53
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Publication
10873583 | J:62890
First Author: Clubb BH
Year: 2000
Journal: Biochem Biophys Res Commun
Title: The 300-kDa intermediate filament-associated protein (IFAP300) is a hamster plectin ortholog.
Volume: 273
Issue: 1
Pages: 183-7
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Publication
10970092 | J:64012
First Author: Yu JX
Year: 2000
Journal: Immunogenetics
Title: Molecular cloning of the C6A form cDNA of the mouse sixth complement component: functional integrity despite the absence of factor I modules.
Volume: 51
Issue: 10
Pages: 779-87
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Publication
3086867 | J:31017
First Author: Itoh H
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.
Volume: 83
Issue: 11
Pages: 3776-80
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Publication
8302156 | J:52068
First Author: Ding D
Year: 1993
Journal: Brain Res Mol Brain Res
Title: Glial cell-specific expression of the serotonin 2 receptor gene: selective reactivation of a repressed promoter.
Volume: 20
Issue: 3
Pages: 181-91
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Publication
7828219 | J:23187
First Author: Korkalainen MK
Year: 1995
Journal: Chem Biol Interact
Title: Comparison of expression of aldehyde dehydrogenase 3 and CYP1A1 in dominant and recessive aryl hydrocarbon hydroxylase-deficient mutant mouse hepatoma cells.
Volume: 94
Issue: 2
Pages: 121-34
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Publication
9379850 | J:42420
First Author: Qian Y
Year: 1997
Journal: Brain Res Mol Brain Res
Title: A Menkes P-type ATPase involved in copper homeostasis in the central nervous system of the rat.
Volume: 48
Issue: 1
Pages: 60-6
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Publication
9524193 | J:46838
First Author: Luegmayr E
Year: 1998
Journal: J Histochem Cytochem
Title: 1,25-Dihydroxy vitamin D3 and tri-iodothyronine stimulate the expression of a protein immunologically related to osteocalcin.
Volume: 46
Issue: 4
Pages: 477-86
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Publication
9687544 | J:49502
First Author: Qian Y
Year: 1998
Journal: J Nutr
Title: Copper efflux from murine microvascular cells requires expression of the menkes disease Cu-ATPase.
Volume: 128
Issue: 8
Pages: 1276-82
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Publication
11790776 | J:75469
First Author: Stout CE
Year: 2002
Journal: J Biol Chem
Title: Intercellular calcium signaling in astrocytes via ATP release through connexin hemichannels.
Volume: 277
Issue: 12
Pages: 10482-8
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Publication
12123838 | J:78198
First Author: Woo HJ
Year: 2002
Journal: FEBS Lett
Title: Escherichia coli 6-pyruvoyltetrahydropterin synthase ortholog encoded by ygcM has a new catalytic activity for conversion of sepiapterin to 7,8-dihydropterin.
Volume: 523
Issue: 1-3
Pages: 234-8
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Publication
14576192 | J:88676
First Author: Hammer F
Year: 2004
Journal: Endocrinology
Title: Transcriptional regulation of P450scc gene expression in the embryonic rodent nervous system.
Volume: 145
Issue: 2
Pages: 901-12
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Publication
16899228 | J:112708
First Author: Wang Y
Year: 2006
Journal: Biochem Pharmacol
Title: Modulation of mitochondrial metabolic function by phorbol 12-myristate 13-acetate through increased mitochondrial translocation of protein kinase Calpha in C2C12 myocytes.
Volume: 72
Issue: 7
Pages: 881-92
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Publication
1400499 | J:2906
First Author: Alam J
Year: 1992
Journal: J Biol Chem
Title: Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene.
Volume: 267
Issue: 30
Pages: 21894-900
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Publication
19121369 | J:146554
First Author: Takarada T
Year: 2009
Journal: Neurosci Lett
Title: Transactivation by Runt related factor-2 of matrix metalloproteinase-13 in astrocytes.
Volume: 451
Issue: 2
Pages: 99-104
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Publication
19995903 | J:159423
First Author: Furmanski AL
Year: 2010
Journal: J Immunol
Title: Peptide-specific, TCR-alpha-driven, coreceptor-independent negative selection in TCR alpha-chain transgenic mice.
Volume: 184
Issue: 2
Pages: 650-7
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Publication
22332887 | J:184292
First Author: Prudencio M
Year: 2012
Journal: J Neurochem
Title: A novel variant of human superoxide dismutase 1 harboring amyotrophic lateral sclerosis-associated and experimental mutations in metal-binding residues and free cysteines lacks toxicity in vivo.
Volume: 121
Issue: 3
Pages: 475-85
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Publication
22287125 | J:187866
First Author: Lee CM
Year: 2012
Journal: Int J Cancer
Title: Optical imaging of MMP expression and cancer progression in an inflammation-induced colon cancer model.
Volume: 131
Issue: 8
Pages: 1846-53
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Publication
22579584 | J:192993
First Author: Sassa T
Year: 2012
Journal: Biochim Biophys Acta
Title: A shift in sphingolipid composition from C24 to C16 increases susceptibility to apoptosis in HeLa cells.
Volume: 1821
Issue: 7
Pages: 1031-7
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Publication
27932310 | J:243051
 
First Author: Voulalas PJ
Year: 2017
Journal: Neuroscience
Title: Loss of dopamine D1 receptors and diminished D1/5 receptor-mediated ERK phosphorylation in the periaqueductal gray after spinal cord lesion.
Volume: 343
Pages: 94-105
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Publication
22041901 | J:327839
First Author: Huang J
Year: 2011
Journal: J Biol Chem
Title: Type II arginine methyltransferase PRMT5 regulates gene expression of inhibitors of differentiation/DNA binding Id2 and Id4 during glial cell differentiation.
Volume: 286
Issue: 52
Pages: 44424-32
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Publication
36450356 | J:340485
First Author: Faouzi A
Year: 2023
Journal: Nature
Title: Structure-based design of bitopic ligands for the µ-opioid receptor.
Volume: 613
Issue: 7945
Pages: 767-774
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Publication
17062636 | J:117129
First Author: Suraweera N
Year: 2006
Journal: Hum Mol Genet
Title: Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.
Volume: 15
Issue: 23
Pages: 3429-35
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Publication
19168680 | J:144016
First Author: Ribes V
Year: 2009
Journal: Development
Title: Early mouse caudal development relies on crosstalk between retinoic acid, Shh and Fgf signalling pathways.
Volume: 136
Issue: 4
Pages: 665-76
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Publication
16495310 | J:144140
First Author: Hill TP
Year: 2006
Journal: Development
Title: Multiple roles of mesenchymal beta-catenin during murine limb patterning.
Volume: 133
Issue: 7
Pages: 1219-29
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Publication
26904955 | J:277959
First Author: Catela C
Year: 2016
Journal: Cell Rep
Title: Hox Proteins Coordinate Motor Neuron Differentiation and Connectivity Programs through Ret/Gfrα Genes.
Volume: 14
Issue: 8
Pages: 1901-15
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Publication
23892084 | J:204470
First Author: Inagawa M
Year: 2013
Journal: Mech Dev
Title: Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.
Volume: 130
Issue: 11-12
Pages: 519-31
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Publication
29379870 | J:262472
 
First Author: Edmond M
Year: 2017
Journal: eNeuro
Title: Topoisomerase IIβ Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs.
Volume: 4
Issue: 6
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Publication
30959515 | J:283357
First Author: Nowotschin S
Year: 2019
Journal: Nature
Title: The emergent landscape of the mouse gut endoderm at single-cell resolution.
Volume: 569
Issue: 7756
Pages: 361-367
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Publication
28188179 | J:247259
First Author: Naruse C
Year: 2017
Journal: FASEB J
Title: New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.
Volume: 31
Issue: 6
Pages: 2252-2266
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Protein
Q80YG3
Organism: Mus musculus/domesticus
Length: 406  
Fragment?: false
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Protein
A0A0A6YWH8
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
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Protein
Q0VDQ8
Organism: Mus musculus/domesticus
Length: 404  
Fragment?: false
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Protein
Q8C939
Organism: Mus musculus/domesticus
Length: 346  
Fragment?: true
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Protein
A2APT9
Organism: Mus musculus/domesticus
Length: 773  
Fragment?: false
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Protein
Q91XA8
Organism: Mus musculus/domesticus
Length: 350  
Fragment?: false
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Protein
Q9D2D9
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
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Protein
Q4G5Y1
Organism: Mus musculus/domesticus
Length: 406  
Fragment?: false
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Protein
Q921I2
Organism: Mus musculus/domesticus
Length: 584  
Fragment?: false
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Protein
Q3USL1
Organism: Mus musculus/domesticus
Length: 350  
Fragment?: false
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Protein
Q6PAR0
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: false
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Protein
A0A0N4SWA7
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
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Protein
Q6PE06
Organism: Mus musculus/domesticus
Length: 444  
Fragment?: false
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Protein
Q8K2U3
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: true
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Protein
V9GXV2
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: false
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Protein
Q3TQM4
Organism: Mus musculus/domesticus
Length: 41  
Fragment?: true
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Protein
Q8C7K3
Organism: Mus musculus/domesticus
Length: 692  
Fragment?: true
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Protein
Q811G7
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: true
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Protein
Q8R577
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: true
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Protein
G3UZG5
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
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Protein
Q8R334
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: false
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Protein
A0A0J9YTT4
Organism: Mus musculus/domesticus
Length: 313  
Fragment?: true
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Protein
A0A338P686
Organism: Mus musculus/domesticus
Length: 280  
Fragment?: true
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Protein
E9Q9M9
Organism: Mus musculus/domesticus
Length: 605  
Fragment?: false
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Protein
G8JL41
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
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Protein
A0A0G2JEQ1
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: true
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Protein
Q9CSA7
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
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Protein
G3X961
Organism: Mus musculus/domesticus
Length: 584  
Fragment?: false
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Protein
Q06BK5
Organism: Mus musculus/domesticus
Length: 361  
Fragment?: false
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Protein
G3UYQ6
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: false
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Protein
A0A286YD60
Organism: Mus musculus/domesticus
Length: 1263  
Fragment?: false
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Protein
F6UW85
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: true
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Protein
G3UZ63
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
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Protein
Q3UWT3
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
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Protein
B2RUK8
Organism: Mus musculus/domesticus
Length: 350  
Fragment?: false
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Protein
A0A087WQT3
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: true
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Protein
A4VCI8
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: true
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Protein
Q05BR3
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Protein
Q8BL42
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
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Protein Domain
IPR020863 | MACPF_CS
Type: Conserved_site
Description: The membrane attack complex/perforin (MACPF) domain is conserved in bacteria, fungi, mammals and plants. It was originally identified and named as being common to five complement components (C6, C7, C8-alpha, C8-beta, and C9) and perforin. These molecules perform critical functions in innate and adaptive immunity. The MAC family proteins and perforin are known to participate in lytic pore formation. In response to pathogen infection, a sequential and highly specific interaction between the constituent elements occurs to form transmembrane channels which are known as the membrane-attack complex (MAC).Only a few other MACPF proteins have been characterised and several are thought to form pores for invasion or protection [, , ]. Examples are proteins from malarial parasites [], the cytolytic toxins from sea anemones [], and proteins that provide plant immunity [, ]. Functionally uncharacterised MACPF proteins are also evident in pathogenic bacteria such as Chlamydia spp []and Photorhabdus luminescens (Xenorhabdus luminescens) [].The MACPF domain is commonly found to be associated with other N- and C-terminal domains, such as TSP1 (see ), LDLRA (see ), EGF-like (see ),Sushi/CCP/SCR (see ), FIMAC or C2 (see ). They probably control or target MACPF function [, ]. The MACPF domain oligomerizes, undergoes conformational change, and is required for lytic activity.The MACPF domain consists of a central kinked four-stranded antiparallel beta sheet surrounded by alpha helices and beta strands, forming two structural segments. Overall, the MACPF domain hasa thin L-shaped appearance. MACPF domains exhibit limited sequence similarity but contain a signature [YW]-G-[TS]-H-[FY]-x(6)-G-G motif [, , ].Some proteins known to contain a MACPF domain are listed below:Vertebrate complement proteins C6 to C9. Complement factors C6 to C9 assemble to form a scaffold, the membrane attack complex (MAC), that permits C9 polymerisation into pores that lyse Gram-negative pathogens [, ].Vertebrate perforin. It is delivered by natural killer cells and cytotoxic T lymphocytes and forms oligomeric pores (12 to 18 monomers) in the plasma membrane of either virus-infected or transformed cells.Arabidopsis thaliana (Mouse-ear cress) constitutively activated cell death 1 (CAD1) protein. It is likely to act as a mediator that recognises plant signals for pathogen infection [].Arabidopsis thaliana (Mouse-ear cress) necrotic spotted lesions 1 (NSL1) protein [].Venomous sea anemone Phyllodiscus semoni (Night anemone) toxins PsTX-60A and PsTX-60B [].Venomous sea anemone Actineria villosa (Okinawan sea anemone) toxin AvTX-60A [].Plasmodium sporozoite microneme protein essential for cell traversal 2 (SPECT2). It is essential for the membrane-wounding activity of the sporozoite and is involved in its traversal of the sinusoidal cell layer prior to hepatocyte-infection [].P. luminescens Plu-MACPF. Although nonlytic, it was shown to bind to cell membranes [].Chlamydial putative uncharacterised protein CT153 [].
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Protein Domain
IPR020864 | MACPF
Type: Domain
Description: The membrane attack complex/perforin (MACPF) domain is conserved in bacteria, fungi, mammals and plants. It was originally identified and named as being common to five complement components (C6, C7, C8-alpha, C8-beta, and C9) and perforin. These molecules perform critical functions in innate and adaptive immunity. The MAC family proteins and perforin are known to participate in lytic pore formation. In response to pathogen infection, a sequential and highly specific interaction between the constituent elements occurs to form transmembrane channels which are known as the membrane-attack complex (MAC).Only a few other MACPF proteins have been characterised and several are thought to form pores for invasion or protection [, , ]. Examples are proteins from malarial parasites [], the cytolytic toxins from sea anemones [], and proteins that provide plant immunity [, ]. Functionally uncharacterised MACPF proteins are also evident in pathogenic bacteria such as Chlamydia spp []and Photorhabdus luminescens (Xenorhabdus luminescens) [].The MACPF domain is commonly found to be associated with other N- and C-terminal domains, such as TSP1 (see ), LDLRA (see ), EGF-like (see ),Sushi/CCP/SCR (see ), FIMAC or C2 (see ). They probably control or target MACPF function [, ]. The MACPF domain oligomerizes, undergoes conformational change, and is required for lytic activity.The MACPF domain consists of a central kinked four-stranded antiparallel beta sheet surrounded by alpha helices and beta strands, forming two structural segments. Overall, the MACPF domain has a thin L-shaped appearance. MACPF domainsexhibit limited sequence similarity but contain a signature [YW]-G-[TS]-H-[FY]-x(6)-G-G motif [, , ].Some proteins known to contain a MACPF domain are listed below:Vertebrate complement proteins C6 to C9. Complement factors C6 to C9 assemble to form a scaffold, the membrane attack complex (MAC), that permits C9 polymerisation into pores that lyse Gram-negative pathogens [, ].Vertebrate perforin. It is delivered by natural killer cells and cytotoxic T lymphocytes and forms oligomeric pores (12 to 18 monomers) in the plasma membrane of either virus-infected or transformed cells.Arabidopsis thaliana (Mouse-ear cress) constitutively activated cell death 1 (CAD1) protein. It is likely to act as a mediator that recognises plant signals for pathogen infection [].Arabidopsis thaliana (Mouse-ear cress) necrotic spotted lesions 1 (NSL1) protein [].Venomous sea anemone Phyllodiscus semoni (Night anemone) toxins PsTX-60A and PsTX-60B [].Venomous sea anemone Actineria villosa (Okinawan sea anemone) toxin AvTX-60A [].Plasmodium sporozoite microneme protein essential for cell traversal 2 (SPECT2). It is essential for the membrane-wounding activity of the sporozoite and is involved in its traversal of the sinusoidal cell layer prior to hepatocyte-infection [].P. luminescens Plu-MACPF. Although nonlytic, it was shown to bind to cell membranes [].Chlamydial putative uncharacterised protein CT153 [].
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Protein Coding Gene
MGI:96186 | Hoxb5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0017028 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019005 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018973 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018946 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96186 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019398 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018731 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018839 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018828 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018909 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018855 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019438 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018085 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018363 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018158 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017874 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
2889591 | J:8869
First Author: Krumlauf R
Year: 1987
Journal: Development
Title: Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1.
Volume: 99
Issue: 4
Pages: 603-17
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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