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Search results 1601 to 1700 out of 20578 for Ca3

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Agtr2/?
Background: involves: 129P2/OlaHsd
Zygosity: ot
Has Mutant Allele: true
Publication  
First Author: Engin E
Year: 2016
Journal: Elife
Title: Modulation of anxiety and fear via distinct intrahippocampal circuits.
Volume: 5
Pages: e14120
Publication      
First Author: Viana da Silva S
Year: 2023
Journal: Neuron
Title: Localized APP expression results in progressive network dysfunction by disorganizing spike timing.
Publication    
First Author: Terauchi A
Year: 2016
Journal: Elife
Title: Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain.
Volume: 5
Allele
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 6; targeted mutation 1, Deltagen
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Transgene
Type: transgene
Organism: mouse, laboratory
Allele
Name: ubiquitin-like modifier activating enzyme 6; targeted mutation 1, Wade Harper
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Genotype
Symbol: Tg(Thy1-TARDBP)4Singh/Tg(Thy1-TARDBP)4Singh
Background: involves: C57BL/6J * SJL/J
Zygosity: hm
Has Mutant Allele: true
GO Term
GO Term
HT Experiment
Series Id: GSE16496
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Tg(UBC-Adk)1Bois/?
Background: B6;129P3-Adk Tg(UBC-Adk)1Bois
Zygosity: ot
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Man2b1/Man2b1
Background: involves: 129 * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Yao W
Year: 2019
Journal: Sci Rep
Title: The Familial dementia gene ITM2b/BRI2 facilitates glutamate transmission via both presynaptic and postsynaptic mechanisms.
Volume: 9
Issue: 1
Pages: 4862
Publication
First Author: Zhu Y
Year: 2017
Journal: J Neurosci
Title: Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation.
Volume: 37
Issue: 31
Pages: 7547-7559
Publication
First Author: Kilonzo K
Year: 2022
Journal: Transl Psychiatry
Title: Distinct contributions of GluA1-containing AMPA receptors of different hippocampal subfields to salience processing, memory and impulse control.
Volume: 12
Issue: 1
Pages: 102
Publication
First Author: Menten-Dedoyart C
Year: 2016
Journal: PLoS One
Title: Development and Validation of a New Mouse Model to Investigate the Role of SV2A in Epilepsy.
Volume: 11
Issue: 11
Pages: e0166525
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Ng D
Year: 2009
Journal: PLoS Biol
Title: Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.
Volume: 7
Issue: 2
Pages: e41
Protein Domain
Type: Family
Description: Neuropilin and tolloid-like protein 1 (Neto1) and 2 (Neto2) share an identical and unique domain structure representing a new subfamily of transmembrane proteins containing CUB (complement C1r/C1s, Uegf, Bmp1) and LDLa (low-density lipoprotein receptor class A) domains []. Neto1 and Neto2 display a complementary expression profile in the mouse brain [, ]. Fast excitatory synaptic transmission in the vertebrate brain is mediated by three classes of ionotropic glutamate receptors: AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors (AMPARs), NMDA (N-methyl-d-aspartate) receptors (NMDARs), and kainate receptors (KARs). Neto1 and Neto2 auxiliary subunits associate with kainate receptors (KARs) to modulate its function [, ]. Some studies also show that Neto1 and Neto2 associate with NMDA receptors (NMDARs) [, ], while one study does not []. Neto1 is required for synaptic plasticity and learning []. In mice, it is highly expressed in the hippocampal CA3 region, olfactory bulb and tubercle, caudate putamen, and neocortex in the adult brain [, , ].
Publication
First Author: Baek J
Year: 2019
Journal: Nature
Title: Neural circuits underlying a psychotherapeutic regimen for fear disorders.
Volume: 566
Issue: 7744
Pages: 339-343
Publication  
First Author: Harada C
Year: 2011
Journal: Nat Commun
Title: Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration.
Volume: 2
Pages: 189
Publication
First Author: White JA
Year: 2008
Journal: Learn Mem
Title: Conditional forebrain deletion of the L-type calcium channel Ca V 1.2 disrupts remote spatial memories in mice.
Volume: 15
Issue: 1
Pages: 1-5
Publication
First Author: McKinney BC
Year: 2008
Journal: Learn Mem
Title: L-type voltage-gated calcium channels in conditioned fear: a genetic and pharmacological analysis.
Volume: 15
Issue: 5
Pages: 326-34
Allele
Name: transgene insertion 1237, Eric R Kandel
Allele Type: Transgenic
Attribute String: Transactivator
Strain
Attribute String: targeted mutation, mutant strain, coisogenic
Allele
Name: transgene insertion 1, Guoping Feng
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 8, Guoping Feng
Allele Type: Transgenic
Attribute String: Reporter
Genotype
Symbol: Grin1/Grin1 Tg(Grik4-cre)G32-4Stl/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Grin2b/Grin2b Grik4/Grik4<+>
Background: C57BL/6-Grin2b Grik4
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Epha4/Epha4 Grik4/Grik4<+>
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Chrm1/Chrm1 Tg(Grik4-cre)G32-4Stl/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cacna1c/Cacna1c Tg(Camk2a-cre)1557Sva/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Reln/Reln
Background: involves: 129S4/SvJaeSor * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Dab1/Dab1
Background: involves: 129S4/SvJaeSor
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Dab1/Dab1
Background: involves: 129S4/SvJaeSor
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Pik3r4/Pik3r4 Emx1/Emx1<+>
Background: involves: 129S2/SvPas * C3H/HeH * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Neurod6/Neurod6<+> Pik3r4/Pik3r4
Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C3H/HeH * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: C3/C3
Background: B6.129S4-C3
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Uba6/Uba6 Tg(Nes-cre)1Kln/?
Background: B6.Cg-Uba6 Tg(Nes-cre)1Kln
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Haws ME
Year: 2012
Journal: Genes Brain Behav
Title: Region-specific deletions of RIM1 reproduce a subset of global RIM1α(-/-) phenotypes.
Volume: 11
Issue: 2
Pages: 201-13
Allele
Name: alpha tubulin acetyltransferase 1; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: transgene insertion 7, Virginia M-Y Lee
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Allele
Name: forkhead box G1; targeted mutation 1, Chunjie Zhao
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: prospero homeobox 1; targeted mutation 1.1, Fumio Matsuzaki
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
MP Term
MP Term
Genotype
Symbol: Gfap/Gfap Vim/Vim
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Fezf1/Fezf1 Fezf2/Fezf2<+>
Background: involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/?
Background: (B6.Cg-Tg(Camk2a-tTA)1Mmay x C3H/HeJ)F1
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/?
Background: (B6.Cg-Tg(Camk2a-tTA)1Mmay x CBA/J)F1
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/?
Background: (B6.Cg-Tg(Camk2a-tTA)1Mmay x DBA/1J)F1
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/?
Background: (B6.Cg-Tg(Camk2a-tTA)1Mmay x FVB/NJ)F1
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/? Fgf14/Fgf14<+>
Background: involves: 129/Sv * C57BL/6 * CBA * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/?
Background: involves: C3H/HeJ * C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/?
Background: (B6.Cg-Tg(Camk2a-tTA)1Mmay x C3H/HeJ)F1 x C3H/HeJ
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: He Y
Year: 2019
Journal: Nat Commun
Title: Amyloid β oligomers suppress excitatory transmitter release via presynaptic depletion of phosphatidylinositol-4,5-bisphosphate.
Volume: 10
Issue: 1
Pages: 1193
Publication
First Author: Szabo GG
Year: 2022
Journal: Neuron
Title: Ripple-selective GABAergic projection cells in the hippocampus.
Volume: 110
Issue: 12
Pages: 1959-1977.e9
Publication
First Author: Engin E
Year: 2015
Journal: J Neurosci
Title: Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference.
Volume: 35
Issue: 40
Pages: 13698-712
Publication
First Author: Straub C
Year: 2011
Journal: Nat Neurosci
Title: Distinct functions of kainate receptors in the brain are determined by the auxiliary subunit Neto1.
Volume: 14
Issue: 7
Pages: 866-73
Publication
First Author: Levenga J
Year: 2011
Journal: Neurobiol Learn Mem
Title: Subregion-specific dendritic spine abnormalities in the hippocampus of Fmr1 KO mice.
Volume: 95
Issue: 4
Pages: 467-72
Publication
First Author: Williams ME
Year: 2011
Journal: Neuron
Title: Cadherin-9 regulates synapse-specific differentiation in the developing hippocampus.
Volume: 71
Issue: 4
Pages: 640-55
Publication
First Author: Wenzel HJ
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Ultrastructural localization of zinc transporter-3 (ZnT-3) to synaptic vesicle membranes within mossy fiber boutons in the hippocampus of mouse and monkey.
Volume: 94
Issue: 23
Pages: 12676-81
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele
Name: angiotensin II receptor, type 2; targeted mutation 1, Tadashi Inagami
Allele Type: Targeted
Attribute String: Null/knockout
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
HT Experiment
Series Id: E-GEOD-67403
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Publication
First Author: Masino SA
Year: 2011
Journal: J Clin Invest
Title: A ketogenic diet suppresses seizures in mice through adenosine A₁ receptors.
Volume: 121
Issue: 7
Pages: 2679-83
Strain
Attribute String: targeted mutation, transgenic, mutant stock
Publication
First Author: Palchykova S
Year: 2010
Journal: J Neurosci
Title: Manipulation of adenosine kinase affects sleep regulation in mice.
Volume: 30
Issue: 39
Pages: 13157-65
Publication
First Author: Fedele DE
Year: 2005
Journal: Brain
Title: Astrogliosis in epilepsy leads to overexpression of adenosine kinase, resulting in seizure aggravation.
Volume: 128
Issue: Pt 10
Pages: 2383-95
Publication  
First Author: Singer P
Year: 2012
Journal: Neuroscience
Title: Working memory and the homeostatic control of brain adenosine by adenosine kinase.
Volume: 213
Pages: 81-92
Publication  
First Author: Wu M
Year: 2013
Journal: Neuroscience
Title: Opiate-induced changes in brain adenosine levels and narcotic drug responses.
Volume: 228
Pages: 235-42
Publication
First Author: Gebril HM
Year: 2023
Journal: Sci Rep
Title: Developmental and foliation changes due to dysregulation of adenosine kinase in the cerebellum.
Volume: 13
Issue: 1
Pages: 19831
Publication
First Author: Yee BK
Year: 2007
Journal: Eur J Neurosci
Title: Transgenic overexpression of adenosine kinase in brain leads to multiple learning impairments and altered sensitivity to psychomimetic drugs.
Volume: 26
Issue: 11
Pages: 3237-52
Publication
First Author: Shimizu K
Year: 2007
Journal: Cell
Title: Proteolytic degradation of SCOP in the hippocampus contributes to activation of MAP kinase and memory.
Volume: 128
Issue: 6
Pages: 1219-29
Publication
First Author: Yasuda T
Year: 2009
Journal: J Neurochem
Title: Effects of UCH-L1 on alpha-synuclein over-expression mouse model of Parkinson's disease.
Volume: 108
Issue: 4
Pages: 932-44
Publication
First Author: Liu Q
Year: 2011
Journal: PLoS Biol
Title: Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system.
Volume: 9
Issue: 1
Pages: e1000575
Publication
First Author: Serrano ME
Year: 2019
Journal: PLoS One
Title: Anxiety-like features and spatial memory problems as a consequence of hippocampal SV2A expression.
Volume: 14
Issue: 6
Pages: e0217882
Publication
First Author: Domenici MR
Year: 2006
Journal: J Neurosci
Title: Cannabinoid receptor type 1 located on presynaptic terminals of principal neurons in the forebrain controls glutamatergic synaptic transmission.
Volume: 26
Issue: 21
Pages: 5794-9
Publication
First Author: Patriarchi T
Year: 2016
Journal: EMBO J
Title: Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor.
Volume: 35
Issue: 12
Pages: 1330-45
Strain
Attribute String: mutant strain, transgenic
Publication
First Author: Havekes R
Year: 2008
Journal: Neurobiol Learn Mem
Title: Transgenic inhibition of neuronal calcineurin activity in the forebrain facilitates fear conditioning, but inhibits the extinction of contextual fear memories.
Volume: 89
Issue: 4
Pages: 595-8
Publication
First Author: Tong G
Year: 2008
Journal: J Neurophysiol
Title: Modulation of NMDA receptor properties and synaptic transmission by the NR3A subunit in mouse hippocampal and cerebrocortical neurons.
Volume: 99
Issue: 1
Pages: 122-32
Publication
First Author: Pitzer C
Year: 2010
Journal: J Neurochem
Title: The hematopoietic factor granulocyte-colony stimulating factor improves outcome in experimental spinal cord injury.
Volume: 113
Issue: 4
Pages: 930-42
Strain
Attribute String: transgenic, mutant stock
Publication      
First Author: Feng G
Year: 2010
Journal: MGI Direct Data Submission
Title: DDS for Tg(Thy1-COP3/EYFP)1Gfng
Genotype
Symbol: Camk2a/Camk2a Tg(Grik4-cre)G32-4Stl/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf Tg(Camk2a-cre)1557Sva/?
Background: involves: 129S1/Sv * 129T2/SvEms * 129X1/SvJ * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Grik4/Grik4<+> Grin1/Grin1
Background: involves: C57BL/6N
Zygosity: cn
Has Mutant Allele: true