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Search results 1601 to 1700 out of 1952 for Cdkn2a

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Type Details Score
Protein Coding Gene
MGP_BALBcJ_G0018218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1261797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018668 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017594 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018004 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018111 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018187 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018129 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017369 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017641 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017455 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017164 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9730623 | J:49773
First Author: Laes JF
Year: 1998
Journal: Cytogenet Cell Genet
Title: Assignment of the cyclin-dependent kinase inhibitor genes Cdkn2a and Cdkn2b to rat chromosome bands 5q32-->q34 and 5q31-->q33, respectively by fluorescence in situ hybridization, using small PCR-generated probes.
Volume: 81
Issue: 3-4
Pages: 290-1
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Allele
Cdkn2aipnl<Gt(AC0187)Wtsi> | MGI:3863817
 
Name: CDKN2A interacting protein N-terminal like; gene trap AC0187, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Cdkn2aipnl<Gt(CC0088)Wtsi> | MGI:3870267
 
Name: CDKN2A interacting protein N-terminal like; gene trap CC0088, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Cdkn2aipnl<Gt(E175A04)Wrst> | MGI:3917039
 
Name: CDKN2A interacting protein N-terminal like; gene trap E175A04, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Cdkn2aipnl<tm1a(KOMP)Wtsi> | MGI:4362329
Name: CDKN2A interacting protein N-terminal like; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cdkn2aipnl<tm1e(KOMP)Wtsi> | MGI:4365148
Name: CDKN2A interacting protein N-terminal like; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cdkn2aipnl<tm1b(KOMP)Wtsi> | MGI:5548411
Name: CDKN2A interacting protein N-terminal like; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cdkn2aipnl<em1Gpt> | MGI:7296719
Name: CDKN2A interacting protein N-terminal like; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cdkn2aipnl<em2Gpt> | MGI:7376343
Name: CDKN2A interacting protein N-terminal like; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:7835667 | C57BL/6N-Cdkn2aip<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7840015 | C57BL/6N-Cdkn2aip<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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DO Term
DOID:0111511 | melanoma and neural system tumor syndrome
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Strain
MGI:6345632 | C57BL/6N-Cdkn2aipnl<tm1a(KOMP)Wtsi>/Mmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:7571040 | C57BL/6NTac-Cdkn2aipnl<tm1a(KOMP)Wtsi>/WtsiOrl
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:6335415 | C57BL/6NTac-Cdkn2aipnl<tm1a(KOMP)Wtsi>/Wtsi
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:5557731 | C57BL/6N-Cdkn2aipnl<tm1b(KOMP)Wtsi>/WtsiOulu
Attribute String: coisogenic, targeted mutation
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Strain
MGI:5797176 | C57BL/6N-Cdkn2aipnl<tm1b(KOMP)Wtsi>/Wtsi
Attribute String: coisogenic, targeted mutation
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Strain
MGI:7381355 | C57BL/6JGpt-Cdkn2aipnl<em2Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Cdkn2aip/Cdkn2aip<+>
Background: C57BL/6NJ-Cdkn2aip/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2aipnl/Cdkn2aipnl
Background: C57BL/6N-Cdkn2aipnl/Wtsi
Zygosity: hm
Has Mutant Allele: true
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Allele
Cdkn2a<em1Smoc> | MGI:6724362
Name: cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cdkn2a<em2Smoc> | MGI:6724363
Name: cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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DO Term
DOID:0080877 | astrocytoma, IDH-mutant, grade 4
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Allele
Tg(TTR-p19Cdkn2a)2Tvd | MGI:3835332
Name: transgene insertion 2, Terry Van Dyke
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6428403 | C57BL/6JSmoc-Cdkn2A<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
16582619 | -
First Author: Tompkins V
Year: 2006
Journal: Cell Cycle
Title: Identification of novel ARF binding proteins by two-hybrid screening.
Volume: 5
Issue: 6
Pages: 641-6
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Publication
17962191 | J:128918
First Author: Montalbano J
Year: 2007
Journal: J Biol Chem
Title: RBEL1 is a novel gene that encodes a nucleocytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer.
Volume: 282
Issue: 52
Pages: 37640-9
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Protein Domain
IPR040385 | RABL6
Type: Family
Description: Rab-like protein 6 (RABL6 or RBEL1) is one of several proteins identified as binding partners of the ARF tumour suppressor, which protects against cancer through protein-protein interactions, interacting with CDKN2A []. RABL6 binds GTP and is found either in the cytoplasm or the nucleus depending in the isoform; isoform 1 is O-glycosylated and cytoplasmic [].
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Strain
MGI:3835334 | B6;D2-Tg(TTR-p19Cdkn2a)2Tvd/Mmnc
Attribute String: transgenic, mutant stock
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Allele
Cdkn2a<tm1.1(cre)Dvb> | MGI:6727119
Name: cyclin dependent kinase inhibitor 2A; targeted mutation 1.1, Dmitry V Bulavin
Allele Type: Targeted
Attribute String: Recombinase, Reporter
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Allele
Cdkn2a<tm2.1(cre/ERT2)Dvb> | MGI:6727120
Name: cyclin dependent kinase inhibitor 2A; targeted mutation 2.1, Dmitry V Bulavin
Allele Type: Targeted
Attribute String: Inducible, Recombinase, Reporter
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Genotype
Genotype
Symbol: Tg(TTR-p19Cdkn2a)2Tvd/?
Background: involves: C57BL/6J * DBA/2J
Zygosity: ot
Has Mutant Allele: true
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Allele
Cdkn2a<tm1Cjs> | MGI:1926877
Name: cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Del(4Cdkn2a-Cdkn2b)2Brn | MGI:3767464
Name: deletion, Chr 4, Anton Berns 2
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cdkn2a<tm4Cjs> | MGI:3842647
Name: cyclin dependent kinase inhibitor 2A; targeted mutation 4, Charles J Sherr
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tg(Cdkn2a-EGFP)GR30Gsat | MGI:4846932
Name: transgene insertion GR30, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Cdkn2a<em4Smoc> | MGI:7262697
Name: cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Cdkn2a<em5Smoc> | MGI:7288908
Name: cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 5, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cdkn2a<em1(flpo,HBEGF/mCherry)Jpmb> | MGI:7514135
Name: cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 1, Juan Pedro Martinez-Barbera
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence, Recombinase, Reporter
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Protein Domain
IPR042015 | MTF2_PHD2
Type: Domain
Description: This entry represents to the second PHD finger found in MTF2.MTF2 (also known as PCL2), complexes with the polycomb repressive complex-2 (PRC2) in embryonic stem cells and regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation []. It recruits the PRC2 complex to the inactive X chromosome and target loci in embryonic stem cells []. Moreover, MTF2 is required for PRC2-mediated Hox cluster repression []. It activates the Cdkn2a gene and promotes cellular senescence, thus suppressing the catalytic activity of PRC2 locally. MTF2 consists of an N-terminal Tudor domain followed by two PHD fingers, and a C-terminal MTF2 domain.
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Protein Domain
IPR042014 | MTF2_PHD1
Type: Domain
Description: This entry represents the first PHD finger found in MTF2.MTF2 (also known as PCL2), complexes with the polycomb repressive complex-2 (PRC2) in embryonic stem cells and regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation []. It recruits the PRC2 complex to the inactive X chromosome and target loci in embryonic stem cells []. Moreover, MTF2 is required for PRC2-mediated Hox cluster repression []. It activates the Cdkn2a gene and promotes cellular senescence, thus suppressing the catalytic activity of PRC2 locally. MTF2 consists of an N-terminal Tudor domain followed by two PHD fingers, and a C-terminal MTF2 domain.
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Publication
27699227 | J:265488
First Author: Hashimoto M
Year: 2016
Journal: JCI Insight
Title: Elimination of p19ARF-expressing cells enhances pulmonary function in mice.
Volume: 1
Issue: 12
Pages: e87732
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Publication
20144788 | J:157068
First Author: Walker E
Year: 2010
Journal: Cell Stem Cell
Title: Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.
Volume: 6
Issue: 2
Pages: 153-66
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Publication
21367819 | J:171509
First Author: Casanova M
Year: 2011
Journal: Development
Title: Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells.
Volume: 138
Issue: 8
Pages: 1471-82
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HT Experiment
GSE185154 | CDKN2A-CDK4-E2F3 dependent oxidative skeletal muscle fiber transition in myogenesis, movement, and metabolism
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:3618472 | B6.129-Cdkn2a<tm1Cjs>/Nci
Attribute String: mutant strain, targeted mutation, congenic
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Strain
MGI:5795640 | B6.129X1-Cdkn2a<tm1Cjs>/KaiJ
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:6331816 | B6.129X1-CdKn2a<tm1Cjs>/Apb
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:3618493 | B6;129-Cdkn2a<tm1Cjs>/Nci
Attribute String: targeted mutation, mutant stock
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Allele
Del(4Cdkn2a-Cdkn2b)1Brn | MGI:3790457
Name: deletion, Chr 4, Anton Berns 1
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:6144437 | B6.129S1-Cdkn2a<tm4Cjs>/Nci
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5538629 | B6.129S1-Cdkn2a<tm4Cjs>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5003700 | STOCK Tg(Cdkn2a-EGFP)GR30Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Allele
Cdkn2a<tm1(cre/ERT2)Mkt> | MGI:6726124
Name: cyclin dependent kinase inhibitor 2A; targeted mutation 1, Makoto Nakanishi
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Strain
MGI:6428404 | C57BL/6JSmoc-Cdkn2a<em4Smoc>
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(4Cdkn2a-Cdkn2b)2Brn/Del(4Cdkn2a-Cdkn2b)2Brn
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(4Cdkn2a-Cdkn2b)2Brn/+
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a
Background: involves: 129X1/SvJ * C57BL/6 * NIH/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+>
Background: involves: 129X1/SvJ * C57BL/6 * NIH/OlaHsd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Kat5/Kat5<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a
Background: involves: 129S1/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a
Background: involves: 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Tacstd2/Tacstd2
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:5892144 | B6.129X1-Dmtf1<tm1Cjs> Cdkn2a<tm1Cjs>/KaiJ
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Tg(Cdkn2a-HBEGF*,-luc)#Masug | MGI:6201264
Name: transgene insertion, Masataka Sugimoto
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Modified isoform(s), Reporter
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Allele
Tg(Cdkn2a-CASP8*,-EGFP)3Jvd | MGI:6467525
Name: transgene insertion 3, Jan MA van Deursen
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Allele
Tg(Cdkn2a-CASP8*,-EGFP)5Jvd | MGI:6467527
Name: transgene insertion 5, Jan MA van Deursen
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Allele
Tg(Cdkn2a/luc/RFP/TK)1Cmps | MGI:6766435
Name: transgene insertion 1, Judith Campisi
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Trp53/Trp53
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(4Cdkn2a-Cdkn2b)1Brn/Del(4Cdkn2a-Cdkn2b)1Brn
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(4Cdkn2a-Cdkn2b)1Brn/+
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Tgfb2/Tgfb2
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Tgfb2/Tgfb2<+>
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
28262675 | J:244308
 
First Author: Lefebure M
Year: 2017
Journal: Nat Commun
Title: Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.
Volume: 8
Pages: 14581
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Protein
Q5U3K5
Organism: Mus musculus/domesticus
Length: 725  
Fragment?: false
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Allele
Cdkn2a<tm3(cre)Cjs> | MGI:3842628
Name: cyclin dependent kinase inhibitor 2A; targeted mutation 3, Charles J Sherr
Allele Type: Targeted
Attribute String: Recombinase
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Strain
MGI:7781325 | C57BL/6JSmoc-Cdkn2a<em4Smoc> Kras<em4Smoc> Tg(Pdx1-cre)1Smoc/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Pdgfrb/Pdgfrb
Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Trp53/Trp53
Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * NIH/OlaHsd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Tg(GFAP-TVA)5Hev/?
Background: involves: 129X1/SvJ * BALB/c * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Rb1/Rb1
Background: involves: 129S2/SvPas * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Publication
26198641 | J:224447
 
First Author: Pencik J
Year: 2015
Journal: Nat Commun
Title: STAT3 regulated ARF expression suppresses prostate cancer metastasis.
Volume: 6
Pages: 7736
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Publication
26997276 | J:234877
First Author: Tamayo-Orrego L
Year: 2016
Journal: Cell Rep
Title: Evasion of Cell Senescence Leads to Medulloblastoma Progression.
Volume: 14
Issue: 12
Pages: 2925-37
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Publication
32025000 | J:291017
First Author: Sethi NS
Year: 2020
Journal: Nat Genet
Title: Early TP53 alterations engage environmental exposures to promote gastric premalignancy in an integrative mouse model.
Volume: 52
Issue: 2
Pages: 219-230
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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