| Type |
Details |
Score |
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jain D |
| Year: |
2017 |
| Journal: |
PLoS Genet |
| Title: |
rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline. |
| Volume: |
13 |
| Issue: |
8 |
| Pages: |
e1006964 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yan C |
| Year: |
2016 |
| Journal: |
Diabetologia |
| Title: |
A decrease in hepatic microRNA-9 expression impairs gluconeogenesis by targeting FOXO1 in obese mice. |
| Volume: |
59 |
| Issue: |
7 |
| Pages: |
1524-1532 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Veeranki S |
| Year: |
2015 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Hyperhomocysteinemia associated skeletal muscle weakness involves mitochondrial dysfunction and epigenetic modifications. |
| Volume: |
1852 |
| Issue: |
5 |
| Pages: |
732-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li C |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
T cell receptor (TCR) and transforming growth factor β (TGF-β) signaling converge on DNA (cytosine-5)-methyltransferase to control forkhead box protein 3 (foxp3) locus methylation and inducible regulatory T cell differentiation. |
| Volume: |
288 |
| Issue: |
26 |
| Pages: |
19127-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Peters SL |
| Year: |
2013 |
| Journal: |
Mol Cell Biol |
| Title: |
Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas. |
| Volume: |
33 |
| Issue: |
21 |
| Pages: |
4321-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dai HQ |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling. |
| Volume: |
538 |
| Issue: |
7626 |
| Pages: |
528-532 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schemmer J |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Transcription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice. |
| Volume: |
8 |
| Issue: |
8 |
| Pages: |
e71113 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang Y |
| Year: |
2012 |
| Journal: |
J Nutr |
| Title: |
A γ-tocopherol-rich mixture of tocopherols maintains Nrf2 expression in prostate tumors of TRAMP mice via epigenetic inhibition of CpG methylation. |
| Volume: |
142 |
| Issue: |
5 |
| Pages: |
818-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morey SR |
| Year: |
2006 |
| Journal: |
Cancer Res |
| Title: |
DNA methylation pathway alterations in an autochthonous murine model of prostate cancer. |
| Volume: |
66 |
| Issue: |
24 |
| Pages: |
11659-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gowher H |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II. |
| Volume: |
109 |
| Issue: |
7 |
| Pages: |
2370-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shirakawa T |
| Year: |
2013 |
| Journal: |
Development |
| Title: |
An epigenetic switch is crucial for spermatogonia to exit the undifferentiated state toward a Kit-positive identity. |
| Volume: |
140 |
| Issue: |
17 |
| Pages: |
3565-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Domingo-Gonzalez R |
| Year: |
2015 |
| Journal: |
Am J Physiol Lung Cell Mol Physiol |
| Title: |
Transforming growth factor-β induces microRNA-29b to promote murine alveolar macrophage dysfunction after bone marrow transplantation. |
| Volume: |
308 |
| Issue: |
1 |
| Pages: |
L86-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamaguchi S |
| Year: |
2013 |
| Journal: |
Nature |
| Title: |
Role of Tet1 in erasure of genomic imprinting. |
| Volume: |
504 |
| Issue: |
7480 |
| Pages: |
460-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Khudaverdyan N |
| Year: |
2024 |
| Journal: |
J Biol Chem |
| Title: |
The structure of DNA methyltransferase DNMT3C reveals an activity-tuning mechanism for DNA methylation. |
| Volume: |
300 |
| Issue: |
9 |
| Pages: |
107633 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Juriloff DM |
| Year: |
2000 |
| Journal: |
Hum Mol Genet |
| Title: |
Mouse models for neural tube closure defects. |
| Volume: |
9 |
| Issue: |
6 |
| Pages: |
993-1000 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Robertson KD |
| Year: |
1999 |
| Journal: |
Nucleic Acids Res |
| Title: |
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. |
| Volume: |
27 |
| Issue: |
11 |
| Pages: |
2291-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xie S |
| Year: |
1999 |
| Journal: |
Gene |
| Title: |
Cloning, expression and chromosome locations of the human DNMT3 gene family. |
| Volume: |
236 |
| Issue: |
1 |
| Pages: |
87-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Weisenberger DJ |
| Year: |
2002 |
| Journal: |
Gene |
| Title: |
Identification and characterization of alternatively spliced variants of DNA methyltransferase 3a in mammalian cells. |
| Volume: |
298 |
| Issue: |
1 |
| Pages: |
91-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lees-Murdock DJ |
| Year: |
2004 |
| Journal: |
Genomics |
| Title: |
Identification of 11 pseudogenes in the DNA methyltransferase gene family in rodents and humans and implications for the functional loci. |
| Volume: |
84 |
| Issue: |
1 |
| Pages: |
193-204 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Datta J |
| Year: |
2005 |
| Journal: |
Cancer Res |
| Title: |
Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells. |
| Volume: |
65 |
| Issue: |
23 |
| Pages: |
10891-900 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li H |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells. |
| Volume: |
281 |
| Issue: |
28 |
| Pages: |
19489-500 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nimura K |
| Year: |
2006 |
| Journal: |
Genes Cells |
| Title: |
Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation. |
| Volume: |
11 |
| Issue: |
10 |
| Pages: |
1225-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fan T |
| Year: |
2008 |
| Journal: |
Epigenetics |
| Title: |
DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development. |
| Volume: |
3 |
| Issue: |
3 |
| Pages: |
134-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fang X |
| Year: |
2016 |
| Journal: |
FASEB J |
| Title: |
Knockdown of DNA methyltransferase 3a alters gene expression and inhibits function of embryonic cardiomyocytes. |
| Volume: |
30 |
| Issue: |
9 |
| Pages: |
3238-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tovy A |
| Year: |
2017 |
| Journal: |
Genes Dev |
| Title: |
p53 is essential for DNA methylation homeostasis in naïve embryonic stem cells, and its loss promotes clonal heterogeneity. |
| Volume: |
31 |
| Issue: |
10 |
| Pages: |
959-972 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Termanis A |
| Year: |
2016 |
| Journal: |
Nucleic Acids Res |
| Title: |
The SNF2 family ATPase LSH promotes cell-autonomous de novo DNA methylation in somatic cells. |
| Volume: |
44 |
| Issue: |
16 |
| Pages: |
7592-604 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Luo G |
| Year: |
2019 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
DNA Methylation Regulates Corneal Epithelial Wound Healing by Targeting miR-200a and CDKN2B. |
| Volume: |
60 |
| Issue: |
2 |
| Pages: |
650-660 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou LY |
| Year: |
2019 |
| Journal: |
Cell Death Differ |
| Title: |
The circular RNA ACR attenuates myocardial ischemia/reperfusion injury by suppressing autophagy via modulation of the Pink1/ FAM65B pathway. |
| Volume: |
26 |
| Issue: |
7 |
| Pages: |
1299-1315 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Watanabe H |
| Year: |
2020 |
| Journal: |
FASEB J |
| Title: |
DNA methylation analysis of multiple imprinted DMRs in Sotos syndrome reveals IGF2-DMR0 as a DNA methylation-dependent, P0 promoter-specific enhancer. |
| Volume: |
34 |
| Issue: |
1 |
| Pages: |
960-973 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miura K |
| Year: |
2021 |
| Journal: |
Biol Reprod |
| Title: |
Generation of chimeric mice with spermatozoa fully derived from embryonic stem cells using a triple-target CRISPR method for Nanos3†. |
| Volume: |
104 |
| Issue: |
1 |
| Pages: |
223-233 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun W |
| Year: |
2020 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Virus-mediated Dnmt1 and Dnmt3a deletion disrupts excitatory synaptogenesis and synaptic function in primary cultured hippocampal neurons. |
| Volume: |
526 |
| Issue: |
2 |
| Pages: |
361-367 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zocher S |
| Year: |
2021 |
| Journal: |
EMBO J |
| Title: |
De novo DNA methylation controls neuronal maturation during adult hippocampal neurogenesis. |
| Volume: |
40 |
| Issue: |
18 |
| Pages: |
e107100 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pandey M |
| Year: |
2014 |
| Journal: |
Exp Mol Pathol |
| Title: |
Involvement of epigenetics and microRNA-29b in the urethane induced inception and establishment of mouse lung tumors. |
| Volume: |
96 |
| Issue: |
1 |
| Pages: |
61-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fanourgakis G |
| Year: |
2025 |
| Journal: |
Nat Commun |
| Title: |
DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos. |
| Volume: |
16 |
| Issue: |
1 |
| Pages: |
465 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
908
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
860
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
796
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park IY |
| Year: |
2005 |
| Journal: |
J Cell Biochem |
| Title: |
Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development. |
| Volume: |
94 |
| Issue: |
3 |
| Pages: |
585-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kutay H |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Reduced susceptibility of DNA methyltransferase 1 hypomorphic (Dnmt1N/+) mice to hepatic steatosis upon feeding liquid alcohol diet. |
| Volume: |
7 |
| Issue: |
8 |
| Pages: |
e41949 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bai S |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2. |
| Volume: |
25 |
| Issue: |
2 |
| Pages: |
751-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tang L |
| Year: |
2024 |
| Journal: |
Am J Physiol Cell Physiol |
| Title: |
DNA methylation of promoter region inhibits galectin-1 expression in BMSCs of aged mice. |
| Volume: |
326 |
| Issue: |
2 |
| Pages: |
C429-C441 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
107
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jiang BC |
| Year: |
2017 |
| Journal: |
J Neurosci |
| Title: |
Promoted Interaction of C/EBPα with Demethylated Cxcr3 Gene Promoter Contributes to Neuropathic Pain in Mice. |
| Volume: |
37 |
| Issue: |
3 |
| Pages: |
685-700 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jiang BC |
| Year: |
2018 |
| Journal: |
J Neurosci |
| Title: |
Demethylation of G-Protein-Coupled Receptor 151 Promoter Facilitates the Binding of Krüppel-Like Factor 5 and Enhances Neuropathic Pain after Nerve Injury in Mice. |
| Volume: |
38 |
| Issue: |
49 |
| Pages: |
10535-10551 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
740
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
421
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
421
 |
| Fragment?: |
false |
|
•
•
•
•
•
|