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Details |
Score |
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Lee CK |
| Year: |
1999 |
| Journal: |
Science |
| Title: |
Gene expression profile of aging and its retardation by caloric restriction. |
| Volume: |
285 |
| Issue: |
5432 |
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•
•
•
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| Publication |
| First Author: |
Wei G |
| Year: |
2020 |
| Journal: |
Development |
| Title: |
Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation. |
| Volume: |
147 |
| Issue: |
17 |
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•
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Chen A |
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2022 |
| Journal: |
Cell |
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Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. |
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185 |
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10 |
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VanDunk C |
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J Neurosci |
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Larsen BM |
| Year: |
2015 |
| Journal: |
Development |
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Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation. |
| Volume: |
142 |
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22 |
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Gacem N |
| Year: |
2020 |
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Nat Commun |
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ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. |
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Kurz J |
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2022 |
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Development |
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Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. |
| Volume: |
149 |
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4 |
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Zhang Q |
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2018 |
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Cell Death Dis |
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Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification. |
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9 |
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Su-Feher L |
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2022 |
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Proc Natl Acad Sci U S A |
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Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia. |
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119 |
| Issue: |
15 |
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Long JE |
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2009 |
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J Comp Neurol |
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Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. |
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| First Author: |
Long JE |
| Year: |
2009 |
| Journal: |
Cereb Cortex |
| Title: |
Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. |
| Volume: |
19 Suppl 1 |
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i96-106 |
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| First Author: |
Prokopuk L |
| Year: |
2022 |
| Journal: |
Reproduction |
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An essential role for Polycomb Repressive Complex 2 in the mouse ovary. |
| Volume: |
163 |
| Issue: |
3 |
| Pages: |
167-182 |
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| First Author: |
Boroviak T |
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2014 |
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Nat Cell Biol |
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The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. |
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16 |
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6 |
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516-28 |
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| First Author: |
Perera SN |
| Year: |
2020 |
| Journal: |
Glia |
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Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. |
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68 |
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12 |
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Mayer C |
| Year: |
2018 |
| Journal: |
Nature |
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Developmental diversification of cortical inhibitory interneurons. |
| Volume: |
555 |
| Issue: |
7697 |
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457-462 |
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| First Author: |
Stevens JD |
| Year: |
2008 |
| Journal: |
Differentiation |
| Title: |
Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation. |
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76 |
| Issue: |
9 |
| Pages: |
1006-22 |
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•
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| First Author: |
Campbell GR |
| Year: |
2011 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling. |
| Volume: |
46 |
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2 |
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548-61 |
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Loo L |
| Year: |
2019 |
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Nat Commun |
| Title: |
Single-cell transcriptomic analysis of mouse neocortical development. |
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10 |
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1 |
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134 |
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| First Author: |
Sansom SN |
| Year: |
2009 |
| Journal: |
PLoS Genet |
| Title: |
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. |
| Volume: |
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Shimizu H |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. |
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10 |
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Tang F |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
Deterministic and stochastic allele specific gene expression in single mouse blastomeres. |
| Volume: |
6 |
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6 |
| Pages: |
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| First Author: |
Yokoyama S |
| Year: |
2009 |
| Journal: |
Dev Cell |
| Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
| Volume: |
17 |
| Issue: |
6 |
| Pages: |
836-48 |
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| First Author: |
Gray PA |
| Year: |
2004 |
| Journal: |
Science |
| Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
| Volume: |
306 |
| Issue: |
5705 |
| Pages: |
2255-7 |
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Thompson CL |
| Year: |
2014 |
| Journal: |
Neuron |
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A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
| Volume: |
83 |
| Issue: |
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| Pages: |
309-323 |
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Visel A |
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2004 |
| Journal: |
Nucleic Acids Res |
| Title: |
GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
| Volume: |
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| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2009 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
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GUDMAP Consortium |
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2004 |
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www.gudmap.org |
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GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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The Gene Ontology Consortium |
| Year: |
2014 |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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Magdaleno S |
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2006 |
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PLoS Biol |
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BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
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Science |
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The transcriptional landscape of the mammalian genome. |
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Nature |
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A conditional knockout resource for the genome-wide study of mouse gene function. |
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Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
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2008 |
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Database Download |
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Mouse Gene Trap Data Load from dbGSS |
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Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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PLoS Biol |
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A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
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Mouse Genome Informatics Scientific Curators |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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MGI Genome Annotation Group and UniGene Staff |
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Database Download |
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MGI-UniGene Interconnection Effort |
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2010 |
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Annotation inferences using phylogenetic trees |
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Mouse Genome Database and National Center for Biotechnology Information |
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Entrez Gene Load |
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Allen Institute for Brain Science |
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Allen Institute |
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Allen Brain Atlas: mouse riboprobes |
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Mouse Genome Informatics Scientific Curators |
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2009 |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
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Database Download |
| Title: |
Consensus CDS project |
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Mouse Genome Informatics Group |
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Database Procedure |
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Automatic Encodes (AutoE) Reference |
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Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
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Protein Ontology Association Load. |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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Obtaining and loading genome assembly coordinates from NCBI annotations |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6441778 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-07-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3518617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:6441783 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Microvascular networks over the brain were abnormal compared with control; but with no phenotype in vascular development. |
| Specimen Label: |
Hes1 KO not shown |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marinopoulou E |
| Year: |
2021 |
| Journal: |
iScience |
| Title: |
HES1 protein oscillations are necessary for neural stem cells to exit from quiescence. |
| Volume: |
24 |
| Issue: |
10 |
| Pages: |
103198 |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakahara F |
| Year: |
2014 |
| Journal: |
Blood |
| Title: |
Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells. |
| Volume: |
123 |
| Issue: |
25 |
| Pages: |
3932-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang T |
| Year: |
2019 |
| Journal: |
Mol Ther Nucleic Acids |
| Title: |
NPAS2 Contributes to Liver Fibrosis by Direct Transcriptional Activation of Hes1 in Hepatic Stellate Cells. |
| Volume: |
18 |
|
| Pages: |
1009-1022 |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
Role of Pax3 acetylation in the regulation of Hes1 and Neurog2. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang H |
| Year: |
2016 |
| Journal: |
Bone |
| Title: |
Use of Hes1-GFP reporter mice to assess activity of the Hes1 promoter in bone cells under chronic inflammation. |
| Volume: |
90 |
|
| Pages: |
80-9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-09-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760621 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:7720113 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Expressed in the apical and basal layers. Coexpressed with Hes1 in the apical cells. |
| Specimen Label: |
2Ca/c/e |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6471699 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-11-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3599820 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6471711 |
| Age: |
embryonic day 12.5 |
|
| Note: |
Authors report no difference among wildtype, Hes1 mutant, Prop1 mutant or double mutant pituitary. |
| Specimen Label: |
E12.5 Wildtype not shown |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6471699 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-11-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3599820 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6471711 |
| Age: |
embryonic day 12.5 |
|
| Note: |
Authors report no difference among wildtype, Hes1 mutant, Prop1 mutant or double mutant pituitary. |
| Specimen Label: |
E12.5 Prop1 mutant not shown |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6471699 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-11-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3599820 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6471711 |
| Age: |
embryonic day 12.5 |
|
| Note: |
Authors report no difference among wildtype, Hes1 mutant, Prop1 mutant or double mutant pituitary. |
| Specimen Label: |
E12.5 Double mutant not shown |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion E, Ryoichiro Kageyama |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion Del1, Ryoichiro Kageyama |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Itaru Imayoshi |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, transgenic |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion C, Ryoichiro Kageyama |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6471705 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-11-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1751822 |
| Pattern: |
Widespread |
| Stage: |
TS22 |
| Assay Id: |
MGI:6471720 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression not affected by loss of Hes1 or Prop individually or by loss of both at E14.5. |
| Specimen Label: |
E14.5 Double mutant not shown |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6471706 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-11-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1751822 |
| Pattern: |
Widespread |
| Stage: |
TS22 |
| Assay Id: |
MGI:6471722 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression not affected by loss of Hes1 or Prop individually or by loss of both at E14.5. |
| Specimen Label: |
E14.5 Prop1 mutant not shown |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6471706 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-11-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1751822 |
| Pattern: |
Widespread |
| Stage: |
TS22 |
| Assay Id: |
MGI:6471722 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression not affected by loss of Hes1 or Prop individually or by loss of both at E14.5. |
| Specimen Label: |
E14.5 Double mutant not shown |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6471705 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-11-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1751522 |
| Pattern: |
Widespread |
| Stage: |
TS22 |
| Assay Id: |
MGI:6471720 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression not affected by loss of Hes1 or Prop individually or by loss of both at E14.5. |
| Specimen Label: |
E14.5 Double mutant not shown |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6471706 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-11-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1751522 |
| Pattern: |
Widespread |
| Stage: |
TS22 |
| Assay Id: |
MGI:6471722 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression not affected by loss of Hes1 or Prop individually or by loss of both at E14.5. |
| Specimen Label: |
E14.5 Prop1 mutant not shown |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6471706 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-11-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1751522 |
| Pattern: |
Widespread |
| Stage: |
TS22 |
| Assay Id: |
MGI:6471722 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression not affected by loss of Hes1 or Prop individually or by loss of both at E14.5. |
| Specimen Label: |
E14.5 Double mutant not shown |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Masamizu Y |
| Year: |
2006 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Real-time imaging of the somite segmentation clock: revelation of unstable oscillators in the individual presomitic mesoderm cells. |
| Volume: |
103 |
| Issue: |
5 |
| Pages: |
1313-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang P |
| Year: |
2010 |
| Journal: |
Oncogene |
| Title: |
Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness. |
| Volume: |
29 |
| Issue: |
20 |
| Pages: |
2916-26 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Hagedorn Research Institute |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, Shin-Ichi Nishikawa |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
hes family bHLH transcription factor 1; targeted mutation 1, L Charles Murtaugh |
| Allele Type: |
Targeted |
| Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Itaru Imayoshi |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 12, Itaru Imayoshi |
| Allele Type: |
Targeted |
| Attribute String: |
Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Dct-Hes1)#Nshk/? |
| Background: |
Not Specified |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takashima Y |
| Year: |
2011 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Intronic delay is essential for oscillatory expression in the segmentation clock. |
| Volume: |
108 |
| Issue: |
8 |
| Pages: |
3300-5 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transgenic, mutant stock |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, mutant stock |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hes1/Hes1<+> |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hes1/Hes1 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hes1/Hes1<+> |
| Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
200
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
71
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
187
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
116
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hes1/Hes1<+> |
| Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
484
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
281
 |
| Fragment?: |
true |
|
•
•
•
•
•
|