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Search results 1601 to 1700 out of 2672 for Mapt

0.018s
Type Details Score
Genotype
Symbol: Tg(Prnp-MAPT)43Vle/Tg(Prnp-MAPT)43Vle
Background: involves: C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT)1Vln/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT)1Vln/Tg(Thy1-MAPT)1Vln
Background: involves: FVB
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT)2Vln/Tg(Thy1-MAPT)2Vln
Background: involves: FVB
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT)5Vln/Tg(Thy1-MAPT)5Vln
Background: involves: FVB
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-MAPT*P301S)PS19Vle/Tg(Prnp-MAPT*P301S)PS19Vle
Background: involves: C3H * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-MAPT*P301S)PS19Vle/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Mapt/Mapt
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT)1Vln/?
Background: FVB/N-Tg(Thy1-MAPT)1Vln
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Mapt/Mapt
Background: FVB.Cg-Mapt
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT*)1Avil/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Mapt-MAPT*)#Hanr/?
Background: involves: BALB/c * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Tuba1-MAPT)14Vle/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Mapt/Mapt
Background: B6.Cg-Mapt
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Unc5d/Unc5d
Background: involves: 129S/SvEv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-MAPT*P301S)PS19Vle/?
Background: B6.Cg-Tg(Prnp-MAPT*P301S)PS19Vle
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT*)1Avil/Tg(Thy1-MAPT*)1Avil
Background: involves: C57BL/6 * CBA
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-MAPT)7Vle/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-MAPT*)2652Gds/?
Background: B6.Cg-Tg(Prnp-MAPT*)2652Gds
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-MAPT*)2652Gds/Tg(Prnp-MAPT*)2652Gds
Background: B6.Cg-Tg(Prnp-MAPT*)2652Gds
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Mapt/Mapt
Background: B6.Cg-Mapt
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nos1ap/Nos1ap Tg(Prnp-MAPT*P301S)PS19Vle/?
Background: involves: C57BL/6 * C3H
Zygosity: cx
Has Mutant Allele: true
HT Experiment
Series Id: GSE68890
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Uusi-Rauva K
Year: 2008
Journal: Exp Cell Res
Title: Novel interactions of CLN3 protein link Batten disease to dysregulation of fodrin-Na+, K+ ATPase complex.
Volume: 314
Issue: 15
Pages: 2895-905
Allele
Name: transgene insertion 183, Jurgen Gotz
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Brody AH
Year: 2022
Journal: Mol Neurodegener
Title: Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy.
Volume: 17
Issue: 1
Pages: 32
Allele
Name: transgene insertion 22, Katharina Schindowski
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Takahashi H
Year: 2024
Journal: Nat Commun
Title: Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase.
Volume: 15
Issue: 1
Pages: 1434
Publication
First Author: Sultanakhmetov G
Year: 2024
Journal: Brain Commun
Title: Mark4 ablation attenuates pathological phenotypes in a mouse model of tauopathy.
Volume: 6
Issue: 3
Pages: fcae136
Publication  
First Author: Dunn-Meynell AA
Year: 2019
Journal: Front Aging Neurosci
Title: In vivo Bioluminescence Imaging Used to Monitor Disease Activity and Therapeutic Response in a Mouse Model of Tauopathy.
Volume: 11
Pages: 252
Publication
First Author: Woo JA
Year: 2017
Journal: Hum Mol Genet
Title: Enhanced tau pathology via RanBP9 and Hsp90/Hsc70 chaperone complexes.
Volume: 26
Issue: 20
Pages: 3973-3988
Publication
First Author: Ono M
Year: 2022
Journal: Aging Cell
Title: Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy.
Volume: 21
Issue: 7
Pages: e13615
Allele
Name: transgene insertion 30, Katharina Schindowski
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 1, Gerard Schellenberg
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: transgenic, mutant strain, congenic
Publication
First Author: Gahring LC
Year: 2017
Journal: PLoS One
Title: Lung epithelial response to cigarette smoke and modulation by the nicotinic alpha 7 receptor.
Volume: 12
Issue: 11
Pages: e0187773
Strain
Attribute String: transgenic, coisogenic
Strain
Attribute String: transgenic, mutant strain, congenic
Strain
Attribute String: congenic, other
Strain
Attribute String: congenic, other
Genotype
Symbol: Tg(Prnp-MAPT*P301L)#Ruvi/Tg(Prnp-MAPT*P301L)#Ruvi
Background: involves: C3HeB/FeJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/?
Background: involves: C57BL/6 * FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-MAPT*K274Q*K281Q)1Lgn/?
Background: involves: C57BL/6 * FVB/N
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Khan SS
Year: 2018
Journal: Acta Neuropathol
Title: Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons.
Volume: 136
Issue: 4
Pages: 589-605
Publication
First Author: Plachta N
Year: 2007
Journal: Nat Neurosci
Title: Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells.
Volume: 10
Issue: 6
Pages: 712-9
Publication
First Author: Lee S
Year: 2014
Journal: J Neurosci
Title: Opposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathway.
Volume: 34
Issue: 37
Pages: 12538-46
Publication
First Author: Barbero-Camps E
Year: 2018
Journal: Autophagy
Title: Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion.
Volume: 14
Issue: 7
Pages: 1129-1154
Publication
First Author: Suenaga K
Year: 2012
Journal: PLoS One
Title: Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brain.
Volume: 7
Issue: 3
Pages: e33218
Publication  
First Author: Vargas-Caballero M
Year: 2017
Journal: Front Neurosci
Title: Wild-Type, but Not Mutant N296H, Human Tau Restores Aβ-Mediated Inhibition of LTP in Tau-/- mice.
Volume: 11
Pages: 201
Publication
First Author: Carvalho K
Year: 2019
Journal: Brain
Title: Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor.
Volume: 142
Issue: 11
Pages: 3636-3654
Publication
First Author: Wisely EV
Year: 2014
Journal: Hum Mol Genet
Title: Genetic suppression of β2-adrenergic receptors ameliorates tau pathology in a mouse model of tauopathies.
Volume: 23
Issue: 15
Pages: 4024-34
Publication
First Author: Marino C
Year: 2024
Journal: Alzheimers Dement
Title: APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation.
Volume: 20
Issue: 2
Pages: 819-836
Publication
First Author: Litvinchuk A
Year: 2018
Journal: Neuron
Title: Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease.
Volume: 100
Issue: 6
Pages: 1337-1353.e5
Strain
Attribute String: transgenic, mutant strain, congenic
Publication
First Author: Engel T
Year: 2008
Journal: Neuroscience
Title: Hippocampal neuronal subpopulations are differentially affected in double transgenic mice overexpressing frontotemporal dementia and parkinsonism linked to chromosome 17 tau and glycogen synthase kinase-3beta.
Volume: 157
Issue: 4
Pages: 772-80
Publication
First Author: Wang B
Year: 2014
Journal: J Neurosci Res
Title: Low-dose total-body carbon-ion irradiations induce early transcriptional alteration without late Alzheimer's disease-like pathogenesis and memory impairment in mice.
Volume: 92
Issue: 7
Pages: 915-26
Publication
First Author: Carroll JC
Year: 2011
Journal: J Neurosci
Title: Chronic stress exacerbates tau pathology, neurodegeneration, and cognitive performance through a corticotropin-releasing factor receptor-dependent mechanism in a transgenic mouse model of tauopathy.
Volume: 31
Issue: 40
Pages: 14436-49
Publication
First Author: Hou TY
Year: 2020
Journal: J Neurochem
Title: Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease.
Volume: 154
Issue: 4
Pages: 441-457
Publication
First Author: Platt B
Year: 2011
Journal: PLoS One
Title: Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1.
Volume: 6
Issue: 11
Pages: e27068
Publication  
First Author: Zheng XY
Year: 2022
Journal: Front Aging Neurosci
Title: Levetiracetam alleviates cognitive decline in Alzheimer's disease animal model by ameliorating the dysfunction of the neuronal network.
Volume: 14
Pages: 888784
Publication
First Author: Ji B
Year: 2008
Journal: J Neurosci
Title: Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies.
Volume: 28
Issue: 47
Pages: 12255-67
Publication
First Author: Jyoti A
Year: 2015
Journal: Neurobiol Aging
Title: Progressive age-related changes in sleep and EEG profiles in the PLB1Triple mouse model of Alzheimer's disease.
Volume: 36
Issue: 10
Pages: 2768-84
Publication  
First Author: Domise M
Year: 2016
Journal: Sci Rep
Title: AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo.
Volume: 6
Pages: 26758
Allele
Name: transgene insertion 1, Frank M LaFerla
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Bajracharya R
Year: 2021
Journal: Acta Neuropathol Commun
Title: Tau antibody isotype induces differential effects following passive immunisation of tau transgenic mice.
Volume: 9
Issue: 1
Pages: 42
Publication
First Author: Pennanen L
Year: 2004
Journal: Neurobiol Dis
Title: Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice.
Volume: 15
Issue: 3
Pages: 500-9
Publication
First Author: Deters N
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Substrate-specific reduction of PP2A activity exaggerates tau pathology.
Volume: 379
Issue: 2
Pages: 400-5
Publication
First Author: Lee SH
Year: 2016
Journal: Cell Rep
Title: Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement.
Volume: 16
Issue: 6
Pages: 1690-1700
Publication  
First Author: Müller-Thomsen L
Year: 2020
Journal: Neurobiol Aging
Title: Consequences of hyperphosphorylated tau on the morphology and excitability of hippocampal neurons in aged tau transgenic mice.
Volume: 93
Pages: 109-123
Publication  
First Author: Köhler C
Year: 2017
Journal: Brain Res
Title: Distribution of spleen tyrosine kinase and tau phosphorylated at tyrosine 18 in a mouse model of tauopathy and in the human hippocampus.
Volume: 1677
Pages: 1-13
Publication  
First Author: Köhler C
Year: 2010
Journal: Brain Res
Title: Analysis of the cholinergic pathology in the P301L tau transgenic pR5 model of tauopathy.
Volume: 1347
Pages: 111-24
Publication
First Author: Pennanen L
Year: 2006
Journal: Genes Brain Behav
Title: Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice.
Volume: 5
Issue: 5
Pages: 369-79
Publication  
First Author: Klingebiel M
Year: 2017
Journal: Brain Res
Title: Analysis of ribosomal protein S6 baseline phosphorylation and effect of tau pathology in the murine brain and human hippocampus.
Volume: 1659
Pages: 121-135
Publication  
First Author: Morcinek K
Year: 2013
Journal: Brain Res
Title: Pattern of tau hyperphosphorylation and neurotransmitter markers in the brainstem of senescent tau filament forming transgenic mice.
Volume: 1497
Pages: 73-84
Publication
First Author: Bi M
Year: 2011
Journal: PLoS One
Title: Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice.
Volume: 6
Issue: 12
Pages: e26860
Publication
First Author: Bodea LG
Year: 2017
Journal: Aging Cell
Title: Accelerated aging exacerbates a pre-existing pathology in a tau transgenic mouse model.
Volume: 16
Issue: 2
Pages: 377-386
Publication
First Author: Meng L
Year: 2022
Journal: Aging Cell
Title: A synapsin â…  cleavage fragment contributes to synaptic dysfunction in Alzheimer's disease.
Volume: 21
Issue: 5
Pages: e13619
Publication
First Author: McAvoy KM
Year: 2019
Journal: PLoS One
Title: Cell-autonomous and non-cell autonomous effects of neuronal BIN1 loss in vivo.
Volume: 14
Issue: 8
Pages: e0220125
Publication
First Author: Jiang L
Year: 2019
Journal: Acta Neuropathol
Title: TIA1 regulates the generation and response to toxic tau oligomers.
Volume: 137
Issue: 2
Pages: 259-277
Publication  
First Author: LeBlang CJ
Year: 2020
Journal: Front Neurosci
Title: Reduction of the RNA Binding Protein TIA1 Exacerbates Neuroinflammation in Tauopathy.
Volume: 14
Pages: 285
Publication
First Author: Apicco DJ
Year: 2019
Journal: Cell Rep
Title: Dysregulation of RNA Splicing in Tauopathies.
Volume: 29
Issue: 13
Pages: 4377-4388.e4
Publication
First Author: Apicco DJ
Year: 2018
Journal: Nat Neurosci
Title: Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo.
Volume: 21
Issue: 1
Pages: 72-80
Publication
First Author: Sanchez-Mico MV
Year: 2021
Journal: Glia
Title: Amyloid-β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease.
Volume: 69
Issue: 4
Pages: 997-1011
Publication
First Author: Min SW
Year: 2015
Journal: Nat Med
Title: Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
Volume: 21
Issue: 10
Pages: 1154-62
Strain
Attribute String: transgenic, mutant strain, congenic
Publication  
First Author: Schindowski K
Year: 2008
Journal: Genes Brain Behav
Title: Neurogenesis and cell cycle-reactivated neuronal death during pathogenic tau aggregation.
Volume: 7 Suppl 1
Pages: 92-100
Publication
First Author: Ahmed T
Year: 2015
Journal: Neurobiol Aging
Title: Rescue of impaired late-phase long-term depression in a tau transgenic mouse model.
Volume: 36
Issue: 2
Pages: 730-9
Publication  
First Author: Zappettini S
Year: 2019
Journal: Front Cell Neurosci
Title: Caffeine Consumption During Pregnancy Accelerates the Development of Cognitive Deficits in Offspring in a Model of Tauopathy.
Volume: 13
Pages: 438
Publication
First Author: Van der Jeugd A
Year: 2011
Journal: Neurobiol Learn Mem
Title: Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission.
Volume: 95
Issue: 3
Pages: 296-304
Publication
First Author: Laurent C
Year: 2014
Journal: Neurobiol Aging
Title: Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology.
Volume: 35
Issue: 9
Pages: 2079-90
Publication
First Author: Audouard E
Year: 2016
Journal: Am J Pathol
Title: High-Molecular-Weight Paired Helical Filaments from Alzheimer Brain Induces Seeding of Wild-Type Mouse Tau into an Argyrophilic 4R Tau Pathology in Vivo.
Volume: 186
Issue: 10
Pages: 2709-22
Publication  
First Author: Gomez-Murcia V
Year: 2020
Journal: Neurobiol Aging
Title: Hyperexcitability and seizures in the THY-Tau22 mouse model of tauopathy.
Volume: 94
Pages: 265-270
Publication
First Author: Zheng J
Year: 2020
Journal: Acta Neuropathol Commun
Title: Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy.
Volume: 8
Issue: 1
Pages: 25
Publication  
First Author: Baltissen D
Year: 2023
Journal: Front Cell Neurosci
Title: APPsα rescues CDK5 and GSK3β dysregulation and restores normal spine density in Tau transgenic mice.
Volume: 17
Pages: 1106176
Publication  
First Author: Leboucher A
Year: 2019
Journal: Neurobiol Dis
Title: Brain insulin response and peripheral metabolic changes in a Tau transgenic mouse model.
Volume: 125
Pages: 14-22
Publication
First Author: Burlot MA
Year: 2015
Journal: Hum Mol Genet
Title: Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology.
Volume: 24
Issue: 21
Pages: 5965-76
Publication
First Author: Leboucher A
Year: 2013
Journal: Diabetes
Title: Detrimental effects of diet-induced obesity on Ï„ pathology are independent of insulin resistance in Ï„ transgenic mice.
Volume: 62
Issue: 5
Pages: 1681-8
Publication
First Author: Chang CP
Year: 2021
Journal: Acta Neuropathol Commun
Title: Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy.
Volume: 9
Issue: 1
Pages: 112
Publication
First Author: Varangot A
Year: 2023
Journal: Cell Death Dis
Title: Modulations of the neuronal trafficking of tissue-type plasminogen activator (tPA) influences glutamate release.
Volume: 14
Issue: 1
Pages: 34
Publication  
First Author: Van der Jeugd A
Year: 2013
Journal: Behav Brain Res
Title: Observations in THY-Tau22 mice that resemble behavioral and psychological signs and symptoms of dementia.
Volume: 242
Pages: 34-9