| Type |
Details |
Score |
| Genotype |
| Symbol: |
Mecp2/Mecp2<+> |
| Background: |
B6.129(FVB)-Mecp2 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE32870 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE24286 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, mutant stock |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2 |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2<+> |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 * CBA |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
involves: 129P2/OlaHsd |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2<+> |
| Background: |
involves: 129P2/OlaHsd |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
involves: 129P2/OlaHsd * C57BL/6J * FVB/N |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
involves: 129P2/OlaHsd * FVB |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
involves: 129P2/OlaHsd * 129S6/SvEvTac |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2 |
| Background: |
involves: 129S6/SvEvTac * 129/SvJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2<+> |
| Background: |
involves: 129S6/SvEvTac * C57BL/6 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
involves: 129S6/SvEvTac * C57BL/6 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
involves: 129S6/SvEvTac * 129/SvJ |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
B6.129P2(C)-Mecp2/J |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2<+> |
| Background: |
B6.129P2(C)-Mecp2/J |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
involves: 129P2/OlaHsd * CD-1 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? |
| Background: |
involves: 129P2/OlaHsd * C57BL/6J |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2 |
| Background: |
involves: 129P2/OlaHsd |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2<+> |
| Background: |
B6.129(FVB)-Mecp2 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2<+> |
| Background: |
B6.129(FVB)-Mecp2 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2 |
| Background: |
B6.129P2(C)-Mecp2/J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
172
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
189
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
482
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE52261 |
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? Tg(MECP2)1Hzo/? |
| Background: |
involves: 129P2/OlaHsd * FVB |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? Tg(MECP2*R270X/GFP)AHzo/? |
| Background: |
involves: 129P2/OlaHsd * FVB |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? Sum1/Sum1<+> |
| Background: |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? Sum2/Sum2<+> |
| Background: |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? Sum4/Sum4<+> |
| Background: |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? Sum5/Sum5<+> |
| Background: |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Del(2Dlx1-Dlx2)1Jlr/+ Mecp2/? |
| Background: |
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
554
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
554
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mapt/Mapt<+> Mecp2/Mecp2<+> |
| Background: |
involves: 129S4/SvJae * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mbd2/Mbd2 Mecp2/? |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? Tg(MECP2*G273X/GFP)AHzo/? |
| Background: |
involves: 129P2/OlaHsd * FVB |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/? Sqle/Sqle<+> |
| Background: |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2 |
| Background: |
B6.129(FVB)-Mecp2 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mecp2/Mecp2 |
| Background: |
B6.129(FVB)-Mecp2 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Witteveen JS |
| Year: |
2016 |
| Journal: |
Nat Genet |
| Title: |
Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity. |
| Volume: |
48 |
| Issue: |
8 |
| Pages: |
877-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mastrototaro G |
| Year: |
2021 |
| Journal: |
Front Cell Dev Biol |
| Title: |
TBL1XR1 Ensures Balanced Neural Development Through NCOR Complex-Mediated Regulation of the MAPK Pathway. |
| Volume: |
9 |
|
| Pages: |
641410 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carrette LLG |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A mixed modality approach towards Xi reactivation for Rett syndrome and other X-linked disorders. |
| Volume: |
115 |
| Issue: |
4 |
| Pages: |
E668-E675 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Apulei J |
| Year: |
2019 |
| Journal: |
Cereb Cortex |
| Title: |
Non-cell Autonomous OTX2 Homeoprotein Regulates Visual Cortex Plasticity Through Gadd45b/g. |
| Volume: |
29 |
| Issue: |
6 |
| Pages: |
2384-2395 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lewis JD |
| Year: |
1992 |
| Journal: |
Cell |
| Title: |
Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. |
| Volume: |
69 |
| Issue: |
6 |
| Pages: |
905-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kameshita I |
| Year: |
2008 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Cyclin-dependent kinase-like 5 binds and phosphorylates DNA methyltransferase 1. |
| Volume: |
377 |
| Issue: |
4 |
| Pages: |
1162-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park J |
| Year: |
2018 |
| Journal: |
Nucleic Acids Res |
| Title: |
Long non-coding RNA ChRO1 facilitates ATRX/DAXX-dependent H3.3 deposition for transcription-associated heterochromatin reorganization. |
| Volume: |
46 |
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22 |
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11759-11775 |
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•
•
•
•
|
| Publication |
| First Author: |
Glaich O |
| Year: |
2019 |
| Journal: |
Nat Commun |
| Title: |
DNA methylation directs microRNA biogenesis in mammalian cells. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
5657 |
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•
•
•
|
| Publication |
| First Author: |
Zhang J |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
m(5)C methylated lncRncr3-MeCP2 interaction restricts miR124a-initiated neurogenesis. |
| Volume: |
15 |
| Issue: |
1 |
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5136 |
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•
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2010 |
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J Neurosci |
| Title: |
Histone methylation regulates memory formation. |
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Subbanna S |
| Year: |
2018 |
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Front Mol Neurosci |
| Title: |
CB1R-Mediated Activation of Caspase-3 Causes Epigenetic and Neurobehavioral Abnormalities in Postnatal Ethanol-Exposed Mice. |
| Volume: |
11 |
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45 |
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Boggio EM |
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2016 |
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Neuroscience |
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Visual impairment in FOXG1-mutated individuals and mice. |
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| Year: |
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| Journal: |
Eur J Hum Genet |
| Title: |
Imbalance of excitatory/inhibitory synaptic protein expression in iPSC-derived neurons from FOXG1(+/-) patients and in foxg1(+/-) mice. |
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2018 |
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Learn Mem |
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miR-132 couples the circadian clock to daily rhythms of neuronal plasticity and cognition. |
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The Cell Adhesion Molecule L1 Interacts with Methyl CpG Binding Protein 2 via Its Intracellular Domain. |
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Hum Mol Genet |
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The long non-coding RNA NEAT1 is elevated in polyglutamine repeat expansion diseases and protects from disease gene-dependent toxicities. |
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Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice. |
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Aging Cell |
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Hyperoxygenation revitalizes Alzheimer's disease pathology through the upregulation of neurotrophic factors. |
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Memory formation and retention are affected in adult miR-132/212 knockout mice. |
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Biochim Biophys Acta |
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Role of DNA methylation and methyl-DNA binding proteins in the repression of 5-lipoxygenase promoter activity. |
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Aberrant DNA hypermethylation patterns lead to transcriptional silencing of tumor suppressor genes in UVB-exposed skin and UVB-induced skin tumors of mice. |
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Neuroscience |
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Ethanol induced acetylation of histone at G9a exon1 and G9a-mediated histone H3 dimethylation leads to neurodegeneration in neonatal mice. |
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PLoS One |
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Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis. |
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Sci Rep |
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Alleviative effects of fluoxetine on depressive-like behaviors by epigenetic regulation of BDNF gene transcription in mouse model of post-stroke depression. |
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Proc Natl Acad Sci U S A |
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Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic. |
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PLoS One |
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Oxidative burden and mitochondrial dysfunction in a mouse model of Rett syndrome. |
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